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    Wyświetlanie 1-8 z 8
    Tytuł:
    Optimal expression and purification of sapelovirus A structural protein VP1, and its immunogenicity in mice
    Autorzy:
    Zhao, T.T.
    Cui, L.
    Chen, L.
    Li, J.J.
    Liang, Q.L.
    Wu, P.J.
    Yu, X.Q.
    Zhang, Z.H.
    Hua, X.G.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087686.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    sapelovirus A
    prokaryotic expression
    purification
    Źródło:
    Polish Journal of Veterinary Sciences; 2018, 21, 3; 573-579
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparative analysis of CpG islands in two genotypes of African swine fever virus
    Autorzy:
    Yu, Y.-Y.
    X, M.-S.
    Liu, Q.
    Powiązania:
    https://bibliotekanauki.pl/articles/16539329.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    African Swine Fever Virus (ASFV)
    genotype
    DNA methylation
    CpG island
    Opis:
    African swine fever (ASF) is an acute, hemorrhagic, and devastating viral infectious disease that causes important economic losses to the swine industry. Currently, there are no effective vaccines or drugs available. Epigenetic mechanisms, especially cytosine methylation of cytosine-phosphate-guanine (CpG) islands, have a significant impact on the life cycle of several viruses. Hence, drugs targeting DNA methylation may potentially be used for the treatment of ASF. Here, we selected the inner core, core shell, inner membrane, capsid, and external envelope membrane, to analyze the characteristics of CpG islands in the ASF virus (ASFV) genomes. Furthermore, we analyzed the promoters and CpG islands in the upstream regions of these genes. Results showed that the CpG islands of seven genes were conserved in the genomes of two genotype of ASFV strains, whereas the CpG islands of other genes were relatively conserved (ASFV strains differed mainly in the quantity of CpG islands). The different distribution of CpG islands in the genomes of different ASFV strains may affect their methylation status, which may in turn affect the regulation of viral gene expression, leading to different clinical outcomes. In addition, the predicted promoter regions based on the upstream sequences of most genes overlapped with CpG island positions. Methylation of the binding sites of the promoter regions inhibits the binding of the transcription factors to the promoters, thus inhibiting the activation of the promoters and limiting the synthesis of viral proteins. The results of this study provide a basis for exploring new antiviral therapeutic strategies from an epigenetic perspective.
    Źródło:
    Polish Journal of Veterinary Sciences; 2022, 25, 3; 455-462
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A Novel Through Capacity Model for One-way Channel Based on Characteristics of the Vessel Traffic Flow
    Autorzy:
    Nie, Y.
    Liu, K.
    Xin, X.
    Yu, Q.
    Powiązania:
    https://bibliotekanauki.pl/articles/115997.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Morski w Gdyni. Wydział Nawigacyjny
    Tematy:
    maritime traffic
    vessel traffic service (VTS)
    vessel traffic flow
    one-way channel
    mathematical model
    Automatic Identification System (AIS)
    Opis:
    Vessel traffic flow is a key parameter for channel-through capacity and is of great significance to vessel traffic management, channel and port design and navigational risk evaluation. Based on the study of parameters of characteristics of vessel traffic flow related to channel-through capacity, this paper puts forward a brand-new mathematical model for one-way channel-through capacity in which parameters of channel length, vessel arrival rate and velocity difference in different vessels are involved and a theoretical calculating mechanism for the channel-through capacity is provided. In order to verify availability and reliability of the model, extensive simulation studies have been carried out and based on the historical AIS data, an analytical case study on the Xiazhimen Channel validating the proposed model is presented. Both simulation studies and the case study show that the proposed model is valid and all relative parameters can be readjusted and optimized to further improve the channel-through capacity. Thus, all studies demonstrate that the model is valuable for channel design and vessel management.
    Źródło:
    TransNav : International Journal on Marine Navigation and Safety of Sea Transportation; 2017, 11, 3; 495-502
    2083-6473
    2083-6481
    Pojawia się w:
    TransNav : International Journal on Marine Navigation and Safety of Sea Transportation
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fiber-optic accelerometer based on a modal interferometer using a thin-core fiber
    Autorzy:
    Wang, X
    Wu, X
    Li, S
    Ge, Q
    He, T
    Yu, B
    Powiązania:
    https://bibliotekanauki.pl/articles/174927.pdf
    Data publikacji:
    2015
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    fiber-optic accelerometer
    modal interferometer
    thin-core fiber
    Opis:
    A compact fiber-optic accelerometer based on a modal interferometer, which is fabricated by misaligned splicing of a short section of a thin-core fiber between two sections of a standard single-mode fiber, is demonstrated experimentally. A spectrum analysis method is used to detect an acceleration signal rapidly. The experimental results show that the thin-core fiber-based fiber-optic accelerometer has a minimum detectable acceleration of 3.3×10–3g (g – gravitational acceleration), and a wide frequency response range from 10 to 1200 Hz. Moreover, the proposed accelerometer exhibits the advantages of low cost, simple structure and easy fabrication.
    Źródło:
    Optica Applicata; 2015, 45, 3; 317-325
    0078-5466
    1899-7015
    Pojawia się w:
    Optica Applicata
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Converged ultra-wideband and multi-level wired signal downstream transport over single wavelength in wavelength-division multiplexing passive optical network
    Autorzy:
    Ma, H
    Wang, F.
    Wang, W.
    Zhang, X
    Yu, Q.
    Powiązania:
    https://bibliotekanauki.pl/articles/174929.pdf
    Data publikacji:
    2015
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    ultra-wideband (UWB)
    multi-level amplitude switch keying (M-ASK)
    wavelength-division multiplexing passive optical network (WDM-PON)
    Opis:
    Simultaneous providing services of ultra-wideband and wired signal over single wavelength can greatly decrease the complexity and reduce the costs of a wavelength-division multiplexing passive optical network. However, ultra-wideband signal occupies the spectrum range from 3.1 to 10.6 GHz, and a narrow idle frequency band (from 0 to 3.1 GHz) could be employed to transport wired signal with a limited rate. In this paper, we proposed a scheme to simultaneously provide ultra-wideband and wired services, in which the information rate of the wired signal is enhanced by employing a multi-level amplitude switch keying signal in the idle frequency band formed by ultra-wideband signal. In comparison with other advanced modulation formats used for wavelength-division multiplexing passive optical networks such as orthogonal frequency division multiplexing, multi-level amplitude switch keying signal can be easily received by using intensity modulation direct detection, which will greatly reduce the cost of end-users. Especially, if a multi-band ultra-wideband signal is substituted for the direct-sequence ultra-wideband signal, the available spectrum range to transport wired signal will be easily extended to 5 GHz as multi-band ultra-wideband signal has a narrower spectrum width and flexible center frequency, so 4-amplitude switch keying signal with a rate of 5 Gbaud will achieve an information rate of 10 Gbit/s.
    Źródło:
    Optica Applicata; 2015, 45, 4; 433-445
    0078-5466
    1899-7015
    Pojawia się w:
    Optica Applicata
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of the microcrack shape, size and direction on the poroelastic behaviors of a single osteon: a finite element study
    Autorzy:
    Cen, H-P.
    Wu, X-G.
    Yu, W-L.
    Liu, Q-Z.
    Yia, Y-M.
    Powiązania:
    https://bibliotekanauki.pl/articles/306642.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    poroelastyczność
    mikropęknięcie
    elementy skończone
    osteon
    poroelasticity
    microcrack
    finite element
    Opis:
    In this work, a finite element study is proposed by using the Comsol Multiphysics software to evaluate the effects of microcrack shape, size and direction on the poroelastic behaviors of a single osteon. Methods: This finite element model is established by using the Comsol Multiphysics software, and we just focus on the comparison of the influences of those microcrack geometric parameters on the osteonal fluid pressure and velocity. Results: The results show that: (1) microcracks in the osteon wall can induce a release of the fluid pressure, but enlarge the velocity in this region; (2) equal-area microcrack with ellipsoid-like shape produced a larger fluid pressure and velocity fields in the osteon than that of rectangular shape; (3) in the elliptic microcracks, the longer of the length (major semi-axis) induces a smaller fluid pressure and velocity amplitudes, whereas the width (minor axis) has little effect; (4) the direction of the microcracks (major axial direction) has an limited influence area around about 1/15 of the osteon cross-sectional area. Conclusions: This model permits the linking of the external loads and microcracks to the osteonal fluid pressure and velocity, which can be used for other purpose associate microcracks with the mechanotransduction and bone remodeling.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2016, 18, 1; 3-10
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pharmacokinetics of the recombinant ovine interferon-tau in lambs
    Autorzy:
    Zhao, J.
    Yu, H.Y.
    Zhao, Y.
    Li, S.Q.
    Fu, X.L.
    Zhou, W.
    Xia, B.B.
    Wang, M.L.
    Chen, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087588.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    bioavailability
    ovine interferon-τ
    cytopathic effect inhibition assay
    pharmacokinetic study
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 1; 75-82
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    17 beta-estradiol affects proliferation and apoptosis of canine bone marrow mesenchymal stem cells in vitro
    Autorzy:
    Zhou, Z.-H.
    Gu, C.-W.
    Li, J.
    Huang, X.-Y.
    Deng, J.-Q.
    Shen, L.-H.
    Cao, S.-Z.
    Deng, J.-L.
    Zuo, Z.-C.
    Wang, Y.
    Ma, X.-P.
    Ren, Z.-H.
    Yu, S.-M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087308.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    apoptosis
    bone marrow mesenchymal stem cells (BMSCs)
    canine
    proliferation
    17 beta-estradiol (E2)
    Źródło:
    Polish Journal of Veterinary Sciences; 2020, 23, 2; 235-245
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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