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    Wyświetlanie 1-11 z 11
    Tytuł:
    Evaluation of differential serum expression of three factors and pulmonary function in patients with silicosis
    Autorzy:
    Zhu, Ying
    Duan, Xia Yu
    Cheng, Yun Qi
    Yao, Xin Jing
    Xu, Hong
    Zhang, Kui Sheng
    Li, Feng Shi
    Yang, Fang
    Liu, Liang He
    Yuan, Xiang Ju
    Powiązania:
    https://bibliotekanauki.pl/articles/2086531.pdf
    Data publikacji:
    2021-08-05
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    silicosis
    pulmonary function
    early diagnosis
    ROC
    PTPN2
    factor B
    Opis:
    ObjectivesSilicosis is a chronic occupational lung disease. As was previously found by the authors, some proteins increased in the lung tissue of activated rats, and protein tyrosine phosphatase non-receptor type 2 (PTPN2), factor B, and vaccinia-related kinase 1 (VRK1) showed highly differential expressions.Material and MethodsIn this study, serum and bronchoalveolar lavage fluid samples were collected from patients with silicosis and healthy people to verify the expression of PTPN2, factor B, and VRK1. The diagnostic value of differentially expressed proteins for silicosis was judged.ResultsThe expression levels of serum PTPN2, VRK1, and factor B in patients with silicosis were significantly higher than those in the control group (p < 0.01). Higher serum PTPN2 and factor B concentrations significantly and negatively correlated with the ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1/FVC), maximum vital capacity (VCmax), FEV1, and FVC, suggesting that the high expression of PTPN2 and factor B is associated with decreased pulmonary ventilation function and restrictive ventilatory impairment in patients with silicosis. All area under curve (AUC) measurements generated from single detection events were >0.744, with PTPN2 reaching the highest value (0.858). The AUC, sensitivity, and specificity for the combined diagnosis using factor B and PTPN2 were 0.907, 86.91% and 85.07%, respectively, for factor B and PTPN2. The 3 differentially expressed proteins are potential classes of predictive biomarkers for silicosis.ConclusionsRegarding the economy and test practicality, the best diagnostic combination is factor B and PTPN2 for the analysis of AUC, sensitivity and specificity.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2021, 34, 4; 527-540
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preparation and environmental toxicity of non-sintered ceramsite using coal gasification coarse slag
    Autorzy:
    Zhao, Shenwei
    Yao, Linying
    He, Haibin
    Zou, Yiping
    Hu, Lei
    Zhai, Yujia
    Yu, Yajing
    Jia, Jianli
    Powiązania:
    https://bibliotekanauki.pl/articles/205064.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    pollution
    coal gasification coarse slag
    waste control
    non-sintered ceramsite
    heavy metal fixation
    Opis:
    In this study, non-sintered ceramsite was prepared using coal gasification coarse slag obtained from a methanol plant. The basic performance and heavy metal leaching toxicity were analyzed. The results showed that seven out of nine non-sintered ceramsite groups were in accordance with the national standard of compressive strength (5 MPa), while only three groups met the national standard of water absorption index of less than 22%. The heavy metal concentrations in these three groups were found to be lower than that specified in National Class IV of surface water environment standards. The concentration of Cr was found to be 16.45 μg/L, which represents only 1% of the IV standard. The optimum mixing ratio, which showed high compressive strength (6.76 MPa) and low water absorption (20.12%), was found to be 73% coal gasification coarse slag, 15% cement, and 12% quartz sand. The characterization using Fourier transform infrared spectroscopy showed that the formation of gelatin in ceramsite enhances the performance of the ceramsite base and increases the immobilization of heavy metal. The study proved that the preparation of non-sintered ceramsite using coal gasification coarse slag reduces its environmental risk and achieves efficient utilization of the slag. Therefore, it can be concluded that it is a feasible and environmental friendly method for the disposal of coal slag.
    Źródło:
    Archives of Environmental Protection; 2019, 45, 2; 84-90
    2083-4772
    2083-4810
    Pojawia się w:
    Archives of Environmental Protection
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Separation of magnesite and calcite based on flotation solution chemistry
    Autorzy:
    Yao, Jin
    Gong, Xiufeng
    Sun, Haoran
    He, Ruofan
    Yin, Wanzhong
    Powiązania:
    https://bibliotekanauki.pl/articles/2146910.pdf
    Data publikacji:
    2022
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    magnesite
    calcite
    reverse flotation
    Opis:
    The dissolution characteristics of minerals, dissolution of flotation agents in solutions, and equilibrium of dissociations and associations serve as the basis for determining the optimal conditions for the effective components of flotation agents and for evaluating the interaction between flotation agents and minerals. This basis provided the theoretical support for the flotation separation of minerals. Based on this, the flotation separation of magnesite and calcite was realized using sodium dihydrogen phosphate, also known as monosodium phosphate (MSP), as a regulator and dodecylamine (DDA) as a collector. When MSP was used in the DDA system, single-mineral and binary mixed-ore flotation tests revealed that the floatability of calcite was significantly greater than that of magnesite and the separation of magnesite and calcite was more effective, respectively. Zeta potential measurements showed that MSP-containing negative groups could selectively reduce the zeta potential of calcite and promote the adsorption of DDA-containing positive groups on the surface of the calcite. However, this effect was negligible on the zeta potential of magnesite. Due to the stronger affinity of MSP to Ca2+ than that to Mg2+, as demonstrated by Fourier transform infrared and X-ray photoelectron spectroscopy analyses, the MSP was adsorbed onto the surface of calcite primarily by hydrogen bonds rather than magnesite, which promoted the stronger adsorption of DDA-containing positive groups on the surface of the calcite. As a result, the differences in the floatability of magnesite and calcite were enlarged by MSP. Thus, MSP can be utilized an effective regulator for the efficient separation of magnesite from calcite via reverse flotation.
    Źródło:
    Physicochemical Problems of Mineral Processing; 2022, 58, 4; art. no. 149398
    1643-1049
    2084-4735
    Pojawia się w:
    Physicochemical Problems of Mineral Processing
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the influence of warning sounds in expressway tunnels on the mental state and attention of the driver
    Autorzy:
    Xiao, Yao
    Liang, Bo
    Wang, Tao
    Niu, Jiaan
    He, Shiyong
    Powiązania:
    https://bibliotekanauki.pl/articles/27312133.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    dźwięk ostrzegawczy
    tunel
    droga ekspresowa
    kierowca
    stan psychiczny
    charakterystyka wizualna
    warning sound
    expressway
    tunnel
    driver
    mental state
    visual characteristic
    Opis:
    In recent years, some expressway tunnels have started broadcasting warning sounds, such as fire alarms, to improve driver attention and traffic safety. However, there is few research on it, and in contrast to previous studies, we have considered different evaluation indices and through field measurement to determine the effectiveness of this practice. The characteristics of three warning sound signals, i.e., fire alarm, dynamic music, and voice command, in a tunnel were analyzed using MATLAB. Considering pupil diameter and blink duration as evaluation indexes, the change in the mental state of the driver after hearing a warning sound was analyzed. Based on Markov chain theory, the change in the gaze region and gaze shift of the driver under the condition of a warning sound was analyzed. Results shows fire alarms and voice commands can increase the mental load of drivers, but the degree of impact was not determined. Dynamic music does not affect the mental load of the driver. The fire alarm and dynamic music attracted the attention of the driver; conversely, as the voice command warns the driver to focus on safety, it did not impact the attention of the driver. The research results provide a scientific reference for the selection of warning sounds in expressway tunnels and new research ideas for the prevention of traffic injuries in expressway tunnels.
    Źródło:
    Archives of Civil Engineering; 2023, 69, 2; 623--636
    1230-2945
    Pojawia się w:
    Archives of Civil Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of nitrogen on growth parameters and photosynthetic characteristics of P. chinense Schneid. Seedlings in three soil types
    Autorzy:
    Wang, Meng-ying
    Wang, Ya-juan
    Ren, Hong-yu
    Yang, Yao
    Gu, Tao
    He, Jing-wen
    Gao, Shun
    Powiązania:
    https://bibliotekanauki.pl/articles/53893751.pdf
    Data publikacji:
    2023
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Opis:
    Soil type and nitrogen (N) are two important factors affecting plant growth and development, and photosynthetic physiological characteristics. However, there are still relatively few studies on the effects of N on P. chinense Schneid. seedlings under different types of soils. In this study, three soil types (red soil, alkaline purple soil, and acidic purple soil) and three N levels (50, 150 and 300 mg/plant) were used to investigate how N levels affected seedling growth, biomass accumulation distribution and photosynthetic characteristics under three soil types. The results showed that N may promote the growth of these seedlings and increase their height and basal stem under three soil types. The stem and leaf biomass, aerial biomass, total biomass, and rootshoot ratio showed significant differences. N increased chlorophyll content in leaves on alkaline purple soil and acidic purple soil, but inhibited chlorophyll synthesis on red soil. Under the same N application, the order for total biomass accumulation in seedlings was alkaline purple soil, red soil, and acid purple soil; for the net photosynthetic rate, it was red soil, acid purple soil, and alkaline purple soil. These results indicate that leaves might elevate the photosynthetic rate by increasing stomatal conductance, intercellular CO2 concentration, and transpiration rate, thereby promoting the growth of seedlings. In addition, soil type and nitrogen had a significant interaction effect on the growth and photosynthetic characteristics of P. chinense Schneid. seedlings. These findings will help screening for suitable soil types and nitrogen application levels for efficient cultivation of P. chinense Schneid. seedlings.
    Źródło:
    Journal of Elementology; 2023, 28, 2; 279-294
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molecular cloning, expression and characterization of Bmserpin-2 gene from Bombyx mori
    Autorzy:
    Pan, Ye
    Xia, Hengchuan
    Lü, Peng
    Chen, KePing
    Yao, Qin
    Chen, Huiqin
    Gao, Lu
    He, Yuanqing
    Wang, Lin
    Powiązania:
    https://bibliotekanauki.pl/articles/1040486.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    serpin-2
    Bombyx mori
    bioinformatics
    subcellular location
    qPCR
    Opis:
    Serpins are a broadly distributed family of protease inhibitors. In this study, the gene encoding Bombyx mori serpin-2 (Bmserpin-2) was cloned and expressed in E. coli. The Bmserpin-2 cDNA contains a 1125 bp open reading frame (ORF). The deduced protein has 374 amino-acid residues, contains a conserved SERPIN domain and shares extensive homology with other invertebrate serpins. RT-PCR analysis showed that Bmserpin-2 was expressed in all developmental stages of B. mori larvae and various larval tissues. Subcellular localization analysis indicated that Bmserpin-2 protein was located in the cytoplasm. Interestingly, real-time quantitative PCR revealed that the expression of Bmserpin-2 in the midgut of susceptible B. mori strain 306 significantly increased at 72 hours post inoculation (hpi) when infected with BmNPV. However, there was no significant increase of the Bmserpin-2 expression in resistant strain NB infected with BmNPV. Thus, our data indicates that Bmserpin-2 may be involved in B. mori antiviral response.
    Źródło:
    Acta Biochimica Polonica; 2009, 56, 4; 671-677
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Different Ignition Responses of Powdery and Bulky 1,3,5-Triamino-2,4,6-trinitrobenzene (TATB) Based Polymer-bonded Explosives under Ultra-high Voltage Electrostatic Discharge
    Autorzy:
    Lyu, Z.
    Long, X.
    Li, Z.
    Dai, X.
    Deng, C.
    He, S.
    Li, M.
    Yao, K.
    Wen, Y.
    Powiązania:
    https://bibliotekanauki.pl/articles/358240.pdf
    Data publikacji:
    2018
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
    Tematy:
    electrostatic spark sensitivity
    ultra-high voltage electrostatic discharge
    thermal effect
    electric field effect
    Opis:
    The electric spark induced ignition mechanism for explosives needs further study. The ignition of powdery and bulky TATB by electrostatic discharge (ESD) was investigated. Up to 200 kV ultra-high voltage ESD was applied to powdery and bulky explosives of two TATB-based polymer-bonded explosives (named PBX-1 and PBX-2). The results showed that the spark sensitivities of powdery and bulky explosives are extremely different for the same formulation. The 50% ignition voltages of powdery PBX-1 and PBX-2 were 10.8 kV and 8.5 kV, respectively, while the values for the bulky samples (tablets) were not less than 200 kV. Both heat and the electric field can be transmitted into the powdery samples, on the other hand only the electric field can be transmitted into the bulk samples. The electric field has a smaller contribution while the heat has a larger contribution to the ignition during an ESD, i.e., the thermal effect plays a main role in the ignition process. Our experimental results are in good agreement with recent results calculated by density functional theory.
    Źródło:
    Central European Journal of Energetic Materials; 2018, 15, 2; 283-298
    1733-7178
    Pojawia się w:
    Central European Journal of Energetic Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Improving Triggering Characteristics for a Surface-Flashover Triggered Vacuum Switch
    Autorzy:
    He, Z.
    Wang, L.
    Li, F.
    Yao, W.
    Dong, M.
    Zhao, C.
    Powiązania:
    https://bibliotekanauki.pl/articles/1807889.pdf
    Data publikacji:
    2009-06
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    52.80.Vp
    52.75.Kq
    52.25.Mq
    Opis:
    A surface-breakdown triggered vacuum switch with parallel disk electrodes and semiconductor surface flashover trigger electrode has many advantages, it is easy to be triggered and machined. The resistance of the trigger gap has been increased in terms of modifying the thickness of the semiconductor layer and improving coating process technology. The trigger gap resistance, trigger voltage and trigger waveforms were experimentally tested. The results show that the triggering characteristics can be improved by increasing the trigger resistance.
    Źródło:
    Acta Physica Polonica A; 2009, 115, 6; 1019-1021
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sequence analysis of human cytomegalovirus US28 gene in low-passage clinical isolates from children and AIDS patients
    Autorzy:
    He, Rong
    Xia, Chang
    Ruan, Qiang
    Qi, Ying
    Ma, Yan-Ping
    Ji, Yao-Hua
    Guo, Jin-Jin
    Powiązania:
    https://bibliotekanauki.pl/articles/1039923.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    chemokine receptors
    cytomegalovirus
    genetic polymorphism
    US28
    Opis:
    Human cytomegalovirus (HCMV) is often a dangerous opportunistic pathogen that causes significant morbidity and mortality in newborn children and immunocompromised patients. The different symptoms and tissue tropisms of HCMV infection may result from genetic polymorphism. This study investigated the sequence variability of the HCMV US28 ORF, which shows sequence homology to the G protein-coupled receptor. HCMV isolated from suspected pediatric cases and isolates from AIDS patients were compared in order to examine the possible associations between polymorphisms and pathogenesis. Seventy children with suspected congenital HCMV infection, who suffered from jaundice (47), megacolon (10), and microcephaly (13), and 17 AIDS patients, were studied. Mutation was prevalent among the sequences of US28, with a focus on the two ends of US28. The important functional groups of US28 are highly conserved. An unrooted tree showed that all sequences from suspected congenitally infected infants and AIDS patients were divided into three groups. Comparison showed that most of the sequences (12/17) from pediatric patients were included in the first group (G1), whereas most of the sequences (11/17) from AIDS patients were included in the third group (G3). The specific high mutation sites in US28 from children were located at the C terminus of the protein, whereas those from AIDS patients were located at the N terminus. We demonstrated the existence of polymorphisms among the US28 genes of clinical isolates of HCMV from infants with suspected congenital infection. Comparison of US28 sequences from AIDS patients with those from children showed that both sequences have their own specific high mutation points.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 2; 231-236
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Numerical test on polystyrene tunnel seismic-isolation material
    Autorzy:
    He, J.
    Chen, W.
    Zhao, W.
    Huang, S.
    Yao, Y.
    Powiązania:
    https://bibliotekanauki.pl/articles/779643.pdf
    Data publikacji:
    2016
    Wydawca:
    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
    Tematy:
    polystyrene plastic foam
    constitutive model
    high intensity
    tunnel
    seismic-isolation layer
    Opis:
    Stress-strain mechanical properties of polystyrene foam plastic material were tested under different loading conditions. An empirical constitutive model for describing metal materials was proposed for the polystyrene plastic foam. The static and dynamic tests results show that the ductility and watertightness of the polystyrene plastic foam are significantly improved. At the same time, in order to check its seismic-isolation property, the high-performance foam concrete as filling materials of Galongla tunnel in Tibet was simulated by FEM. The simulated results show that the polystyrene plastic foam can remarkably decrease the stress and the plastic zone in final lining, so it can effectively reduce the seismic damage of the tunnel. Considering the seismic-isolation property and low price of polystyrene plastic foam, it is a good reference for the anti-seismic design of tunnels in high intensity zones.
    Źródło:
    Polish Journal of Chemical Technology; 2016, 18, 3; 122-127
    1509-8117
    1899-4741
    Pojawia się w:
    Polish Journal of Chemical Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An adaptive method based on PC-Kriging for system reliability analysis of truss structures
    Autorzy:
    Chen, Pengyu
    Zhao, Cunbao
    Yao, He
    Zhao, Shengnan
    Powiązania:
    https://bibliotekanauki.pl/articles/27312783.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
    Tematy:
    trade-off
    truss structures
    system reliability analysis
    global metamodel
    local metamodel
    representative failure modes
    Opis:
    In practice, a truss consists of a large number of members which makes it a complex system. This leads to difficulties to estimate the system reliability due to computational costs. An adaptive method is thereby proposed to deal with this issue. It constructs a global metamodel to quickly estimate the rough reliability index of a truss. According to the estimated reliability index, the differential evolution algorithm is performed to generate more samples located in an expanded domain so that more representative failure modes can be identified. Combined with AK-SYSi, local metamodels of representative failure mods are built, and updated through active learning. When the convergence criterion is satisfied, the results of system reliability analysis can be obtained. Eventually, two examples of truss structures are studied to illustrate the superiority of the proposed method in balancing accuracy and efficiency. The results indicate that the proposed method makes a good balance between accuracy and efficiency when it is applied to analyze the system reliability of the truss.
    Źródło:
    Eksploatacja i Niezawodność; 2023, 25, 3; art. no. 169497
    1507-2711
    Pojawia się w:
    Eksploatacja i Niezawodność
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-11 z 11

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