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    Tytuł:
    The IOERT IntraLine accelerator : the development, current state, and future plans
    Autorzy:
    Adrich, P.
    Hanke, R.
    Kulczycka, E.
    Kosiński, K.
    Meglicki, B.
    Misiarz, A.
    Pławski, E.
    Staszczak, M.
    Swat, K.
    Syntfeld-Każuch, A.
    Wójtowicz, M.
    Wysocka-Rabin, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/148309.pdf
    Data publikacji:
    2016
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    radiotherapy
    mobile electron accelerator
    intraoperative electron radiation therapy (IOERT)
    Opis:
    Intraoperative electron radiation therapy (IOERT) is a cancer treatment method that combines oncologic surgery with electron beam radiotherapy. This method can reduce the duration of entire tumor treatment and increase its effectiveness. Moreover, shortening the treatment time signifi cantly reduces the cost and accessibility of the therapy. As a result of interdisciplinary research, an innovative accelerator for IOERT, the IntraLine, was developed. In the course of this work, four patent applications were fi led. Today, the work is half way through. In the near future, the device will be optimized. New mechanical design solutions will be developed. Mechanical optimization will signifi cantly reduce the weight of the device. Accelerators control system, which today is in the demo phase, will also be signifi cantly upgraded. This paper describes the stages of the IntraLine accelerator development, its current state and plans for the future R&D work, within the scope of our new Intra-Dose project.
    Źródło:
    Nukleonika; 2016, 61, 1; 3-9
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Monte Carlo study on a new concept of a scanning photon beam system for IMRT
    Autorzy:
    Wysocka-Rabin, A. M.
    Hartmann, G. H.
    Powiązania:
    https://bibliotekanauki.pl/articles/147603.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    Monte Carlo (MC) simulations
    medical accelerators
    intensity-modulated radiation therapy (IMRT)
    Opis:
    Intensity-modulated radiation therapy (IMRT) is almost exclusively realized using a multi-leaf collimator (MLC). In this work we investigated alternative approaches to realize an IMRT - scanning photon beam system. The technical realization of this concept required investigating the influence of various design parameters on the final small photon beam. This was done using Monte Carlo (MC) simulation methods. The resulting photon beam that is to be scanned should have a diameter well less than 10 mm at a source-surface distance (SSD), and the penumbra should be as small as possible. A first draft for this system, based on the PRIMUS 6 MV accelerator at DKFZ (Deutsches Krebsforshungszentrum), was proposed and modeled using the BEAMnrc/EGSnrc MC code. We then proposed and studied a new geometry of the source-target-collimator system. Calculations were done for 108 particles, using an electron energy cut-off (ECUT) = 0.7 MeV, and a photon energy cut-off (PCUT) = 0.01 MeV. The influence of different collimator parameters, different target construction and various incident electron beam characteristics was studied. Calculations of the dose absorbed in the water were performed for 8 different collimators at a distance of 40 cm from the collimator exit, which is the medical requirement. Results of the dose distribution calculations are presented as photon beam profiles with the values of full width at half-maximum (FWHM) and penumbra (PM) for every beam profile. The influence of target construction was studied for different thicknesses of target and material minimizing electron contamination. The influence of the following characteristics of the incident electron beam was also investigated: size of electron beam, energy, displacement of the beam from the axis of target-collimator system, shape of the electron beam profile. The field dose distribution of the photon beam was calculated for the collimators giving the beam profiles. Basing on the work performed in this investigation, it will be possible to define adequate parameters for the target-collimator system as well as on the scanning electron beam for new IMRT system.
    Źródło:
    Nukleonika; 2011, 56, 4; 291-297
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Simulation of computed tomography (CT) images using a Monte Carlo approach
    Autorzy:
    Wysocka-Rabin, A. M.
    Qamhiyeh, S.
    Jäkel, O.
    Powiązania:
    https://bibliotekanauki.pl/articles/147601.pdf
    Data publikacji:
    2011
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    X-ray tomography
    Monte Carlo (MC) method
    treatment planning
    hadrontherapy
    Opis:
    Heavy ion treatment planning uses an empirical scanner-dependent calibration relation between computed tomography (CT) numbers and ion range. Any deviation in the values of CT numbers will cause a drift in the calibration curve of the CT scanner, which can reduce the accuracy of treatment beam delivery. To reduce uncertainty in the empirical estimation of CT numbers, we developed a simulation that takes into consideration the geometry, composition, and physical process that underlie their measurement. This approach uses Monte Carlo (MC) simulations, followed by a simple filtered back-projection reconstruction. The MC code used is BEAMnrc/EGSnrc. With the manufacturer’s permission, we simulated the components (X-ray tube, associated filters and beam shapers) of a Siemens Emotion CT. We then generated an initial beam shape and spectra, and performed further simulations using the phantom with substitutes. We analyzed the resulting phase space file to calculate projections, taking into account the energy response of the CT detectors. Then, we applied a simple reconstruction algorithm to the calculated projections in order to receive the CT image.
    Źródło:
    Nukleonika; 2011, 56, 4; 299-304
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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