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    Wyświetlanie 1-5 z 5
    Tytuł:
    Model considering residual stiffness and stiffness discontinuity of bolted joints
    Autorzy:
    Wang, Sheng-Ao
    Zhu, Min
    Xu, Zi-Jian
    Guo, Ming
    Li, Biao
    Wu, Fei
    Powiązania:
    https://bibliotekanauki.pl/articles/2087050.pdf
    Data publikacji:
    2022
    Wydawca:
    Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
    Tematy:
    nonlinear dynamic behaviour
    Iwan model
    energy dissipation
    Opis:
    The nonlinear dynamic behavior has an important impact on energy dissipation and vibra- tion damping characteristics of bolted joints. Firstly, the development of tangential dynamic models is summarized and analyzed. Secondly, a five-parameter Iwan model based on a trun- cated power-law distribution is proposed. The backbone and hysteresis curves are obtained. Thirdly, normalized and dimensionless analysis is performed. On the basis of the above, a more concise four-parameter Iwan model with stiffness continuity is proposed. Finally, the validity of the model is verified by comparing the energy dissipation vs excitation force amplitude curve with the experimental data.
    Źródło:
    Journal of Theoretical and Applied Mechanics; 2022, 60, 1; 63--75
    1429-2955
    Pojawia się w:
    Journal of Theoretical and Applied Mechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Hereditary Equality of Domination and Exponential Domination in Subcubic Graphs
    Autorzy:
    Chen, Xue-Gang
    Wang, Yu-Feng
    Wu, Xiao-Fei
    Powiązania:
    https://bibliotekanauki.pl/articles/32324524.pdf
    Data publikacji:
    2021-11-01
    Wydawca:
    Uniwersytet Zielonogórski. Wydział Matematyki, Informatyki i Ekonometrii
    Tematy:
    dominating set
    exponential dominating set
    subcubic graphs
    Opis:
    Let γ(G) and γe(G) denote the domination number and exponential domination number of graph G, respectively. Henning et al., in [Hereditary equality of domination and exponential domination, Discuss. Math. Graph Theory 38 (2018) 275–285] gave a conjecture: There is a finite set ℱ of graphs such that a graph G satisfies (H) = γe(H) for every induced subgraph H of G if and only if G is ℱ-free. In this paper, we study the conjecture for subcubic graphs. We characterize the class ℱ by minimal forbidden induced subgraphs and prove that the conjecture holds for subcubic graphs.
    Źródło:
    Discussiones Mathematicae Graph Theory; 2021, 41, 4; 1067-1075
    2083-5892
    Pojawia się w:
    Discussiones Mathematicae Graph Theory
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cloning and characterization of the yak gene coding for calpastatin and in silico analysis of its putative product
    Autorzy:
    Zhang, Liping
    Ma, Binyun
    Wu, Jianping
    Fei, Chunhong
    Yang, Lian
    Wan, Hongling
    Powiązania:
    https://bibliotekanauki.pl/articles/1040417.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    calpastatin
    yak
    domain
    motif
    functional site
    calpaincalpastatin system
    Opis:
    The calcium-activated neutral proteases, μ- and m-calpain, along with their inhibitor, calpastatin, have been demonstrated to mediate a variety of Ca2+-dependent processes including signal transduction, cell proliferation, cell cycle progression, differentiation, apoptosis, membrane fusion, platelet activation and skeletal muscle protein degradation. The cDNA coding for yak calpastatin was amplified and cloned by RT-PCR to investigate and characterize the nucleotide/amino-acid sequence and to predict structure and function of the calpastatin. The present study suggests that the yak calpastatin gene encodes a protein of 786 amino acids that shares 99 % sequence identity with the amino-acid sequence of cattle calpastatin, and that the yak protein is composed of an N-terminal region (domains L and XL) and four repetitive homologous C-terminal domains (d1–d4), in which several prosite motifs are present including short peptide L54–64 (EVKPKEHTEPK in domain L) and GXXE/ DXTIPPXYR (in subdomain B), where X is a variable amino acid. Our results suggest the existence of other functional sites including potential phosphorylation sites for protein kinase C, cAMP- and cGMP-dependent protein kinase, casein kinase II, as well as N-myristoylation and amidation sites that play an important role in molecular regulation of the calpain/calpastatin system. The regulation of the calpain/calpastatin system is determined by the interaction between dIV and dVI in calpains and subdomains A, B, and C in calpastatin.
    Źródło:
    Acta Biochimica Polonica; 2010, 57, 1; 35-41
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Stigmasterol blocks cartilage degradation in rabbit model of osteoarthritis
    Autorzy:
    Chen, Wei-Ping
    Yu, Chong
    Hu, Peng-Fei
    Bao, Jia-Peng
    Tang, Jing-Li
    Wu, Li-Dong
    Powiązania:
    https://bibliotekanauki.pl/articles/1039645.pdf
    Data publikacji:
    2012
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    matrix metalloproteinases
    stigmasterol
    osteoarthritis
    Opis:
    Stigmasterol has been shown exihbit anti-osteoarthritic properties in vitro studies. However, the in vivo effects of stigmasterol on cartilage are still unclear. This study investigated the anti-osteoarthritic properties of stigmasterol on cartilage degradation in a rabbit model of osteoarthritis (OA). Twenty rabbits underwent bilateral anterior cruciate ligament transection (ACLT) to induce OA. Five rabbits were used as normal control. Two weeks after operation, the rabbits were randomly divided into two groups. Each group of 10 rabbits received intra-articular injection with 0.3 ml of stigmasterol in left knees and vehicle in right knees, once weekly. Group 1 was killed 6 weeks after ACLT and 2 were sacrificed 9 weeks after ACLT. The knee joints were assessed by gross morphology, histology and gene expression analysis. We found that expression of genes encoding matrix metalloproteinases (MMPs) was significantly higher while tissue inhibitors of metalloproteinase (TIMP)-1 was significantly lower in the both joints of the two OA groups compared to normal contrals. Stigmasterol reduced the cartilage degradation as assessed by histological analysis and markedly suppressed MMPs expression both in group 1 and group 2. Our results suggest that stigmasterol may be considered as a possible therapeutical agent in the treatment of OA.
    Źródło:
    Acta Biochimica Polonica; 2012, 59, 4; 537-541
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Temporal and spatial heterogeneity of the Ailaoshan–Song Ma–Song Chay ophiolitic mélange, and its significance on the evolution of Paleo-Tethys
    Autorzy:
    Lin, Wei
    Liu, Fei
    Wang, Ying
    Meng, Lingtong
    Faure, Michel
    Chu, Yang
    Nguyen, Vuong Van
    Wu, Qinying
    We, Wei
    Thu, Hoai Luong Thi
    Vu, Tich Van
    Powiązania:
    https://bibliotekanauki.pl/articles/24202127.pdf
    Data publikacji:
    2023
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
    Tematy:
    Tethys
    heterogeneity
    Vietnam
    Opis:
    The ophiolite is the direct evidence to restore the oceanic evolution, and it is used to identify the convergence boundary of the plates. Compared with ophiolite, ophiolitic mélange, especially its matrix, contains more information about the evolution of ocean. The evolution of eastern Paleo-Tethys, between the South China and Indochina blocks, recorded the whole process of rifting from Gondwana and their northward migration and convergence. To understand the tectonic implications from matrix of ophiolitic mélange, the Mesozoic Paleo-Tethys Ailaoshan–Song Ma–Song Chay suture zone located in the North Vietnam–Southeast Yunnan region acts as an ideal study area. Based on the structural geology, we reviewed previous zircon U-Pb dating and Lu-Hf isotopic analyses on the detrital zircon from the Ailaoshan–Song Ma–Song Chay ophiolitic mélange. Accordingly, we subdivide the matrix of these ophiolitic mélange into four parts (M1, M2, M3, and M4; Fig. 1). M1 is mainly located in the middle segment of the Ailaoshan–Song Ma belt. It shows age peaks of 440 Ma and 960 Ma with εHf(t) values of −19.6 ~ +10.3. M2 is mainly located in the NW segment of the Ailaoshan–Song Ma belt, showing a dominant age peak of ~260 Ma. Particularly, it has εHf(t) values of −28.9 ~ +8.1. M3 is mainly located in the SE segment of the Ailaoshan–Song Ma belt, showing the peaks at ~250 Ma, 440 Ma, and 960 Ma with εHf(t) values of −21.9 ~ +10.1. M4 is mainly located in the Song Chay belt, showing the peaks at ~310 Ma, 470 Ma, 610 Ma, 770 Ma, and 965 Ma with εHf(t) values of −28.2 ~ +10.8. The geochronological data of the detrital zircon from the matrix of the Ailaoshan– Song Ma–Song Chay ophiolitic mélange zone, documents a temporal heterogeneity between the M1, M2, M3, and M4 units, which formed at 310–270 Ma, 265–250 Ma, 245–240 Ma, and 310–255 Ma, respectively. The different components and provenances of each unit reflect a strike-parallel heterogeneity (Fig. 1). The M1 unit was mainly sourced from the Paleozoic sedimentary rocks of the Indochina Block (IB). The main provenance for the M2 unit is Emeishan Large Igneous Province (ELIP). The magmatic arc developed in the IB provided the materials for the M3 unit, and the detrital materials of the M4 were mainly sourced from the South China Block (SCB) (Fig. 1). The Cenozoic strike-slip deformation led to an inverted geometry of the M1, M2, and M3 units, accounting for a strike-perpendicular heterogeneity straight to the strike of the orogenic belt. The temporal, strike-parallel, and strike-perpendicular heterogeneity help us to decipher the tempo-spatial evolution of the Paleo-Tethys. The M1, M2, M3, and M4 units contain information from different evolutionary stages, likely recording the comprehensive history of the ancient oceanic basin. Importantly, our results demonstrate that both the active continental margin of the IB and the passive continental margin of the SCB acted as provenance sources that supplied significant amount of detrital material in the ophiolitic mélange matrix, indicating that the Paleo-Tethys Ocean was a “narrow” or “limited” ocean rather than the archipelagic ocean proposed before.
    Źródło:
    Geotourism / Geoturystyka; 2023, 1-2 (72-73); 42--43
    1731-0830
    Pojawia się w:
    Geotourism / Geoturystyka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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