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Tytuł:
Development of Process Conditions for the Preparation of Copper Alloys Post-Production Chips for the Continuous Casting Process
Autorzy:
Malec, Witold
Cwolek, Beata
Brudny, Anna
Kulasa, Joanna
Marek, W.
Stolorz, K.
Wróbel, D.
Filipowicz, A.
Powiązania:
https://bibliotekanauki.pl/articles/27314152.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
waste
recycling
bronze
moisture of waste
continuous casting
odpady poprodukcyjne
recykling
brąz
wilgotność odpadów
odlewanie ciągłe
Opis:
The paper presents the results of research aimed at developing assumptions for the preparation of a charge in the form of fine scrap copper alloys (chips/shells) guaranteeing effective removal of impurities and obtaining a metal bath of the required metallurgical quality. The tests were conducted for tin-zinc-lead bronze of the CC499K grade. As part of the work, the characteristics of this type of waste available on the market were made in terms of quality and the possibility of their use for the production of both alloys and finished products, taking into account the elimination of harmful impurities that may ultimately affect the production process adversely. The subject of the work was the selection of appropriate waste cleaning methods in the form of an oily shell in the CC499K (CuZn5Sn5Pb2) grade and its drying in terms of increasing the use of impure waste from machining as scrap for direct melting. The waste was assessed in relation to individual parameters. The research was carried out on 3 groups of waste, with varying degrees of moisture.
Źródło:
Archives of Foundry Engineering; 2023, 23, 2; 43--50
1897-3310
2299-2944
Pojawia się w:
Archives of Foundry Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
InAs light-to-heavy hole effective mass ratio determined experimentally from mobility spectrum analysis
Autorzy:
Wróbel, Jarosław
Umana-Membreno, Gilberto A.
Boguski, Jacek
Złotnik, Sebastian
Kowalewski, Andrzej
Moszczyński, Paweł
Antoszewski, Jarek
Faraone, Lorenzo
Wróbel, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/2204210.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Stowarzyszenie Elektryków Polskich
Tematy:
indium arsenide
effective masses
energy band warping
magnetotransport
mobility spectrum analysis
Opis:
Careful selection of the physical model of the material for a specific doping and selected operating temperatures is a non-trivial task. In numerical simulations that optimize practical devices such as detectors or lasers architecture, this challenge can be very difficult. However, even for such a well-known material as a 5 μm thick layer of indium arsenide on a semiinsulating gallium arsenide substrate, choosing a realistic set of band structure parameters for valence bands is remarkable. Here, the authors test the applicability range of various models of the valence band geometry, using a series of InAs samples with varying levels of p-type doping. Carefully prepared and pretested the van der Pauw geometry samples have been used for magneto-transport data acquisition in the 20-300 K temperature range and magnetic fields up to ±15 T, combined with a mobility spectra analysis. It was shown that in a degenerate statistic regime, temperature trends of mobility for heavy- and light-holes are uncorrelated. It has also been shown that parameters of the valence band effective masses with warping effect inclusion should be used for selected acceptor dopant levels and range of temperatures.
Źródło:
Opto-Electronics Review; 2023, 31, Special Issue; art. no. e144567
1230-3402
Pojawia się w:
Opto-Electronics Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
New Ecological Cast Bronzes for Fittings Manufactured from Recycled Waste
Autorzy:
Malec, Witold
Cwolek, Beata
Brudny, Anna
Juszczyk, Barbara
Kulasa, Joanna
Hury, Anna
Marek, W.
Stolorz, K.
Wróbel, D.
Filipowicz, A.
Powiązania:
https://bibliotekanauki.pl/articles/27314124.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
wastes
recycling
continuous casting
machining bronze
lead-free copper alloy
odpady
recykling
odlewanie ciągłe
obróbka brązu
bezołowiowy stop miedzi
Opis:
The article presents tests on a new lead-free bronze CuSn4Zn2PS, intended for fittings for contact with drinking water, in which the addition of lead was replaced with sulphur. The subject of the experimental work was the production of semi-finished products from this alloy based on the charge coming entirely from waste generated after machining. A specialized pilot line was used for the tests, and after cleaning, the waste was melted and then were continuously cast in the form of rods and hollow rods. The cleaning efficiency was assessed, and the manufactured semi-finished products were subjected to tests, including the assessment of the chemical and mechanical homogeneity and the structure of the test batch of the semi-finished casting products in terms of the possibility of manufacturing products meeting the requirements of technical specifications. The obtained results, both in terms of a stable chemical composition, homogeneous and reproducible mechanical properties, fully compliant with the specifications for fittings bronzes (CC499K), as well as the lack of faults of the obtained semi-finished products, despite a very large share of waste material, indicate the possibility of using the tested recycling method for the production of semi-products of sulphur bronze, which is an alloy that is relatively difficult to manufacture.
Źródło:
Archives of Foundry Engineering; 2023, 23, 1; 37--42
1897-3310
2299-2944
Pojawia się w:
Archives of Foundry Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The selected agrotechnical factors affecting the occurrence of black grass Alopecurus myosuroides in winter wheat crops in north-western Poland
Wybrane czynniki agrotechniczne wpływające na występowanie wyczyńca polnego Alopecurus myosuroides w uprawach pszenicy ozimej w północno-zachodniej Polsce
Autorzy:
Wróbel, M.
Jaroszewska, A.
Podsiadło, C.
Sobolewska, M.
Powiązania:
https://bibliotekanauki.pl/articles/29432357.pdf
Data publikacji:
2023
Wydawca:
Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
Źródło:
Agronomy Science; 2023, 78, 3; 147-159
2544-4476
2544-798X
Pojawia się w:
Agronomy Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Commercial Kevlar derived activated carbons for CO2 and C2H4 sorption
Autorzy:
Kaliszewski, M.
Zgrzebnicki, M.
Kałamaga, A.
Pinjara, S.
Wróbel, R. J.
Powiązania:
https://bibliotekanauki.pl/articles/1849281.pdf
Data publikacji:
2021
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
activated carbon
carbonaceous catalysts
autoxidation
alpha-pinene
iron particles
biomass
Opis:
The carbonaceous precursor was obtained via pyrolysis of commercial aramid polymer (Kevlar). Additionally the precursor was activated at 1000°C in CO2 atmosphere for different times. Obtained materials were characterised by BET; XPS; SEM and optical microscopy. The sorption capacities were determined by temperature swing adsorption performed in TGA apparatus for CO2 and C2H4 gases. The obtained materials exhibit high difference in sorption of these gases i.e. 1.5 and 2.8 mmol/g @30°C respectively and high SSA ~1600 m2/g what can be applied in separation applications. The highest uptakes were 1.8 and 3.1 mmol/g @30°C respectively. It was found that the presence of oxygen and nitrogen functional groups enhances C2H4/CO2 uptake ratio.
Źródło:
Polish Journal of Chemical Technology; 2021, 23, 2; 81-87
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of Molding Materials on the Self-Hardening of X46Cr13 Steel / Grey Cast Iron Bimetallic Castings
Autorzy:
Przyszlak, N.
Wróbel, T.
Dulska, A.
Powiązania:
https://bibliotekanauki.pl/articles/2049571.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
bimetallic casting
grey cast iron
tool steel
hardness
microstructure
Opis:
The paper presents the problem which concerning the technology of bimetallic castings in materials configuration: high-chromium steel as the working layer and grey cast iron as the base part. The aim of the studies was integrate the process of manufacturing of bimetallic casting with the heat treatment of hardening type of X46Cr13 steel insert by applying the mould with sandmix on a matrix of chromite sand. Range of studies included the chemical composition analysis, non-destructive ultrasonic tests to examine the quality of the permanent bond between the working layer (steel insert) and the base part (grey cast iron) of the bimetallic castings, hardness measurements as well as metallographic examinations performed on the optical and scanning electron microscopes. On the basis of obtained results was concluded that the self-hardening process occurred in the X46Cr13 steel working layer and in result of this the hardness on its surface equalled approx. 45HRC in case of the bimetallic castings with full permanent bond between both parts.
Źródło:
Archives of Metallurgy and Materials; 2021, 66, 1; 43-50
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quality of life among patients from urban and rural areas with advanced age-related macular degeneration assessed using the NEI-VFQ-25
Autorzy:
Święch, A.
Dolar-Szczasny, J.
Wróbel-Dudzińska, D.
Kosior-Jarecka, E.
Mackiewicz, J.
Powiązania:
https://bibliotekanauki.pl/articles/28762776.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2021, 28, 2; 243-249
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of parents’ satisfaction with caring for children hospitalized in a pediatric ward – part 1
Autorzy:
Kremska, A.
Kołodziej, B.
Wróbel, R.
Kraśnianin, E.
Zych, B.
Ignac, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087605.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
personal satisfaction
parents
delivery of health care
patient care management
Opis:
Background: The quality of medical services offered is a factor that strongly determines patient satisfaction. Aim of the study: The aim of the study was to evaluate parent’s satisfaction with the care and conditions experienced during their child’s stay in a Pediatric Ward. Material and methods: The study involved 293 parents from two pediatric wards of the Clinical Provincial Hospital No. 2 in Rzeszow. The PASAT PEDIATRIA package was used as a research tool. Results: The functioning of the admission room was good. Parents of children on the Pediatric Ward ranked medical and nursing friendliness the highest (mean = 4.34 and 4.37, respectively), followed by the availability of doctors (mean = 3.97) and the amount of time they devoted to the patient’s family (mean = 3.97). Respondents assessed the ward best in terms of the cleanliness of the room (mean = 4.12) and the possibility of spending free time in an interesting way (mean = 4.07). Conclusions: Parents of children hospitalized in the Pediatric Ward were slightly more satisfied with nursing than medical care. Doctors should make every effort to improve the availability and amount of time devoted to the child’s family. The overall assessment of the conditions in the ward was “fairly good”, indicating the need for monitoring and improvement.
Źródło:
Medical Science Pulse; 2020, 14, 4; 18-24
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of the impact of sodium and potassium metabolism in women undergoing hysteroscopy due to pathological uterine bleeding
Autorzy:
Zielinski, P.
Szeszko, L.
Krupinska, J.
Wrobel, G.
Szeszko, A.
Oszukowski, P.
Powiązania:
https://bibliotekanauki.pl/articles/1192474.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
Tematy:
gynaecology
menstruation
menstrual disorders
abnormal uterine bleeding
kalium
natrium
endomentrial hyperplasia
endometrial polyp
heavy menstruation
uterine fibroids
Opis:
Monitoring the water and electrolyte balance is an integral part of diagnostics and designing an effective therapy of many diseases. Sodium and potassium play a crucial role in the diagnosis of water and electrolyte disorders. The study was conducted to demonstrate the relationship between the occurrence of electrolyte disturbances in women undergoing hysteroscopy due to pathological uterine bleeding. Medical records of 543 patients aged 21-88 (52.8±11.8 years) hospitalized in the Gynecology and Obstetrics Department of the Provincial Specialist Hospital in Biała Podlaska, who underwent hysteroscopic diagnostics due to pathological bleeding from the uterus were collected. 212 women (39.04%) were diagnosed with pathological bleeding from the uterus, 147 women (27.07%) had endomentrial hyperplasia, 104 women (19.15%) were diagnosed with an endometrial polyp, 62 women (11.42%) suffered from heavy menstruations and 18 women (3.3%) had uterine fibroids. The sodium and potassium concentrations were measured using an automated Cobas® 8000 analyzer (Roche). The average concentration of sodium in the serum was 139.84±2.13 mmol L-1 (χ 2 = 35.079; P<0.001), and the average potassium concentration was 4.44±0.37 mmol L-1 (χ 2 = 36.019; P<0.001). Higher values for sodium were recorded in the group of patients with adenomyosis (140.41±2.27 mmol L-1) and patients with uterine fibroids (140.11±1.94) mmol L-1). Statistically significant differences were found in mean sodium concentration values depending on the causes of patients’ hospitalization (H=33.914; P<0.001), and the biggest differences were between patients with ovulation disorders and patients with adenomyosis: 138.86±0.21 mmol L-1 vs. 140.41±2.27 mmol L-1 (Z=5.169; P<0.001). It seems important add measurements of sodium and potassium concentrations to the profile of tests performed in the diagnosis of gynaecological patients referred for hysteroscopy for the reasons presented in the study in order to reduce the risk of complications associated with the loss of these elements.
Źródło:
Journal of Elementology; 2020, 25, 3; 1199-1212
1644-2296
Pojawia się w:
Journal of Elementology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The relationship between study addiction and examination stress among students of music academies
Autorzy:
Atroszko, Paweł A.
Wróbel, Wiktor K.
Bereznowski, Piotr
Lawendowski, Rafał
Powiązania:
https://bibliotekanauki.pl/articles/2125136.pdf
Data publikacji:
2020-01-10
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
musicians
examination stress
learning engagement
personality
study addiction
workaholism
work addiction
Opis:
Previous studies have shown that study addiction is related to worse academic performance among music academy students as well as in the general population of students, suggesting that excessive examination stress may impair their performance on exams. The aim of this study was to investigate the relationship between the newly developed concept of “study addiction” and examination stress among students of music academies. Study addiction has been defined within the framework of theory and research on work addiction as a potential behavioral addiction. A cross-sectional correlational study was conducted, with a sample of 132 students of music academies in Poland. The Bergen Study Addiction Scale, assessing seven core addiction symptoms related to studying, was administered together with a commonly used measure of personality and single-item measures of examination stress and learning engagement. Multiple hierarchical regression analysis showed that study addiction was related to higher examination stress above and beyond personality traits. What is more, while study addiction showed a positive relationship with examination stress, learning engagement showed a negative association with examination stress. The results suggest that, among music academies students, study addiction is related to higher stress during exams and that study addiction and learning engagement are different constructs. Taking into account the relationship of study addiction with higher stress in situations of being evaluated, future studies are warranted that would link study addiction to music performance anxiety, which is one of the most widely studied phenomena in the psychology of music.
Źródło:
Roczniki Psychologiczne; 2019, 22, 2; 177-192
1507-7888
Pojawia się w:
Roczniki Psychologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of simulation-based training in neonatal cardiopulmonary resuscitation complicated by meconium aspiration syndrome
Autorzy:
Zych, B.
Błaż, W.
Muster, M.
Kraśnianin, E.
Wróbel, R.
Kremska, A.
Błajda, J.
Raba, G.
Powiązania:
https://bibliotekanauki.pl/articles/2087796.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
newborns
simulation
meconium aspiration syndrome
cardiopulmonary resuscitation
education
midwives
Opis:
Background: The use of simulation-based training is strategic in training medical staff. Aim of the study: The aim of the study was to assess the knowledge and skills of performing neonatal CPR (cardiopulmonary resuscitation) complicated by the presence of meconium in the respiratory tract in two groups of midwives (trained in the traditional tutorial-based model vs simulation-based training) with an interactive neonatal manikin. Material and methods: The knowledge and practical skills assessment was conducted in two groups of midwives. The knowledge of the participants was assessed using both a written test consisting of 25 control questions (5 questions on meconium aspiration syndrome, 20 on neonatal CPR) and practical skills including 12 activities (1-initial, 9-proper, 2-final). The complex “success” indicator was determined based on the effects of patient resuscitation (15 minutes of the scenario), and the reference point for knowledge and skills was to obtain a minimum of 70% correct answers/activities performed, evaluated by three independent experts. Results: In the knowledge test, the respondents scored 17.93 ± 3.11 points out of 25 (71.7%). Practical skills for all respondents were 17.57 ± 2.49 points out of 21 (83.66%), with a tendency to obtain higher points in cleaning of the airways and stimulation of the newborn, and lower for ventilation and the use of an alternative method of intubation. Despite the similar level of practical skills in both groups, only a higher statistical tendency was observed in three out of nine instrumented “proper activities” in the simulation trained midwives. Conclusions: The scenario used by us assessing the knowledge and skills of midwives taught in traditional tutorial-based and simulation-based training, indicates the advantage of acquiring individual competences in a short time using simulation-based training. This increasingly popular scientific model allows the acquisition of “invasive” competencies, but it requires further research.
Źródło:
Medical Science Pulse; 2020, 14, 3; 25-30
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
With regard to the autonomy in maritime operations – hydrography and shipping, interlinked
Autorzy:
Wróbel, K.
Weintrit, A.
Powiązania:
https://bibliotekanauki.pl/articles/1841580.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Morski w Gdyni. Wydział Nawigacyjny
Tematy:
maritime operations
hydrography
shipping
ECDIS
autonomous vessels
marine hydrography
safe navigation
Opis:
With change being the only thing that is constant, modern world is undergoing a disruptive change to many aspects of everyday life. Covering 70% of our planet, oceans and industries connected with them are of no exception. The apparent drive towards autonomization in shipping will not only change the way vessels are navigated, but will affect virtually all services needed for the vessels to be navigated. These include not only the design of ships themselves, training of their crews, remote supervision of onboard processes, but also the extremely important - yet not always appreciated - domain that allows for a safe navigation: maritime hydrography. This paper discusses some insights on how the autonomous vessels and future hydrographers may benefit from each other.
Źródło:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation; 2020, 14, 3; 745-749
2083-6473
2083-6481
Pojawia się w:
TransNav : International Journal on Marine Navigation and Safety of Sea Transportation
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Women’s expectations and preferences for care of the newborn in the immediate postpartum period
Autorzy:
Kremska, A.
Zych, B.
Wróbel, R.
Kraśnianin, E.
Jeżowska, M.
Powiązania:
https://bibliotekanauki.pl/articles/2087970.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
perinatal care
expectations
midwife
standard
Opis:
Background: The Regulation of the Minister of Health issued on 16th August 2018 addressed the matter of the organizational standard of perinatal care which determines guidelines concerning care of the newborn baby, in which skin-to-skin contact and early breastfeeding are important. Aim of the study: The aim of this study is to explore women’s preferences concerning care of the newborn in the immediate postpartum period. Material and methods: 130 patients attending the Pro-Familia specialist hospital in Rzeszow participated in this research. The cohort consisted of pregnant women who had attended the doctor supervising their pregnancy before delivery. The research was carried out from March to April 2013 and the data collected was statistically analyzed, assuming a significance level of p<0.05. Results: Pregnant women most often expressed a preference of an accompanying person to cut the newborn’s umbilical cord (59.2%), with 23.1% preferring a member of the medical team to do so. The majority (89.2%) of pregnant women wanted their baby to be laid on their stomach immediately following delivery to ensure skin-to-skin contact. In terms of Apgar scoring, 69.2% of women expected information about the Apgar score of their newborn immediately after delivery. Most women (60%) wished their newborn to be given routine vaccinations for hepatitis B and tuberculosis (BCG). Patients most often declare that they want to breastfeed exclusively (77.7%), with 29.2% of women expressing a wish to obtain more information about breastfeeding and 31.5% wishing to consult with a lactation specialist. Conclusions: Pregnant women expect skin-to-skin contact immediately after delivery, the umbilical cord to be cut by an accompanying person and would like to be told their newborn’s Apgar score. The women studied prefer exclusively breastfeeding, and express a wish to obtain information regarding lactation, and expect to be able to consult with a lactation specialist.
Źródło:
Medical Science Pulse; 2020, 14, 2; 30-35
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antagonistic interaction of lacosamide with carbamazepine and valproate in the mouse tonic-clonic seizure model
Antagonistyczna interakcja lakozamidu z karbamazepiną i walproainianem w modelu drgawek toniczno-klonicznych u myszy
Autorzy:
Kondrat-Wróbel, M.W.
Załuska, K.
Walczak, A.
Panasiuk-Poterek, A.N.
Gut-Lepiech, A.
Wróblewska-Łuczka, P.
Łuszczki, J.J.
Powiązania:
https://bibliotekanauki.pl/articles/2053463.pdf
Data publikacji:
2019
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
antiepileptic drugs
isobolography
maximal electroshock
three-drug combination
antagonism
leki przeciwpadaczkowe
izobolografia
elektrowstrząsy
kombinacja trzech leków
antagonizm
Opis:
Background. It is estimated that approximately 1% of people worldwide suffer from epilepsy. Currently available antiepileptic drugs (AEDs) are able to control epileptic seizures in about 70% of cases. In the remaining patients (30%), the application of two or three AEDs in combination is necessary for effective seizure management. The goal of this work was to characterize the interaction of three AEDs: lacosamide (LCM), carbamazepine (CBZ) and valproate (VPA) at the fixed-ratio of 1:1:1 in the mouse tonic-clonic seizure model. Material and methods. Male albino Swiss mice, after receiving a combination of LCM, CBZ and VPA, were challenged with electric current to evoke tonic hind limb extension (seizure activity). Protection of the mice from tonic-clonic seizures was assessed by isobolographic analysis to determine the type of interaction occurring between these drugs. Results. Type I isobolographic analysis revealed that the combination of LCM, CBZ and VPA produced infra-additive (antagonistic) interaction in the mouse tonic-clonic seizure model. Conclusions. Since the three-drug mixture of LCM, CBZ a nd VPA exerted an antagonistic interaction in the tonic-clonic seizure test in mice, we would caution physicians against treating epilepsy patients with this unfavorable combination.
Wprowadzenie. Szacuje się, że około 1% osób na całym świecie cierpi na padaczkę. Obecnie dostępne leki przeciwpadaczkowe pozwalają na opanowanie napadów padaczkowych w około 70% przypadków. U pozostałych pacjentów z padaczką (30%) konieczne jest zastosowanie dwóch lub trzech leków przeciwpadaczkowych w kombinacji. Celem pracy było scharakteryzowanie interakcji między trzema lekami przeciwpadaczkowymi: lakozamidem (LCM), karbamazepiną (CBZ) i walproinianem (VPA) w stałym stosunku dawek 1:1:1 w modelu drgawek toniczno-klonicznych u myszy. Materiał i metody. Samce myszy albino Swiss, po otrzymaniu kombinacji LCM, CBZ i VPA, poddano działaniu prądu elektrycznego, aby wywołać toniczny wyprost kończyn tylnych (aktywność drgawkową). Ochronę myszy przed napadami toniczno-klonicznymi oszacowano za pomocą analizy izobolograficznej, aby określić typ interakcji zachodzącej między tymi lekami. Wyniki. Analiza izobolograficzna typu I ujawniła, że kombinacja LCM, CBZ i VPA powodowała oddziaływanie infra-addytywne (antagonistyczne) w modelu drgawek toniczno-klonicznych u myszy. Wnioski. Ponieważ trójlekowa mieszanina LCM, CBZ i VPA wywierała antagonistyczną interakcję w teście napadów toniczno-klonicznych u myszy, specjalne ostrzeżenie jest konieczne dla lekarzy, aby nie leczyć pacjentów z padaczką tą niekorzystną kombinacją.
Źródło:
Health Problems of Civilization; 2019, 13, 1; 92-98
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of the Stress Relaxation of Biodegradable Surgical Threads Made of Mg and Zn Alloys and Some Commercial Synthetic Materials
Autorzy:
Milenin, A.
Kustra, P.
Wróbel, M.
Paćko, M.
Byrska-Wójcik, D.
Powiązania:
https://bibliotekanauki.pl/articles/352186.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Ax30
Zn
surgical threads
relaxation
mechanical properties
Opis:
The mechanical properties of the commercial synthetic surgical threads (i.e., monofilament MonosynR and polyfilament PolysorbTM) and threads made of pure zinc and selected magnesium alloys were compared. Tensile and relaxation tests of fine fibers/wires without and with a surgical knot were performed on a Zwick 250 tensile machine and on the specially constructed tensile machine dedicated for ultra-thin samples. An about 50% decrease in the maximum tensile load was registered for both synthetic and Mg-based threads due to the presence of a surgical knot while only an about 10% decrease was documented for the zinc threads.
Źródło:
Archives of Metallurgy and Materials; 2019, 64, 3; 1139-1143
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
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