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    Wyświetlanie 1-3 z 3
    Tytuł:
    Persistence of long-term insulin independence after islet transplantation and two subsequent pregnancies
    Autorzy:
    Gondek, Sarah
    Ogledzinski, Mateusz
    Lin, William
    Milejczyk, Kamila
    Juengel, Braden
    Potter, Lisa
    Bachul, Piotr J.
    Basto, Lindsay
    Perea, Laurencia
    Wang, Ling-Jia
    Tibudan, Martin
    Witkowska, Zuzanna
    Barth, Rolf
    Fung, John
    Witkowski, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/2203248.pdf
    Data publikacji:
    2023-06-07
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    pregnancy
    insulin
    islet transplantation
    Opis:
    Pregnancy increases metabolic demand for insulin and may lead to the exhaustion of intraportally transplanted islets and post-gestational hyperglycemia. To prevent these complications, we implemented preemptive insulin supplementation during two subsequent pregnancies in an insulin-independent islet transplant recipient. This strategy resulted in optimal blood glucose control during the pregnancies, the preservation of the optimal islet graft function and the postpartum maintenance of long-term insulin independence.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2023, 6, 1; 9-13
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dealing with hypodysfibrinogenemia during pregnancy with a successful outcome
    Autorzy:
    Faflik, Zuzanna
    Witkowski, Michał
    Witkowska, Magdalena
    Smolewski, Piotr
    Robak, Tadeusz
    Powiązania:
    https://bibliotekanauki.pl/articles/2047810.pdf
    Data publikacji:
    2021-11-08
    Wydawca:
    Medical Education
    Tematy:
    hypodysfibrinogenemia
    pregnancy
    fibrynogen
    substitution
    Opis:
    Background: Fibrinogen is a protein playing pleiotropic role in human body. It is engaged in maintaining hemostasis. Congenital fibrinogen disorders comprise quantitative and qualitative fibrinogen anomalies. The symptoms range from bleeding, thrombosis to asymptomatic at all what is the most common case. Hypodysfibrinogenemia with lower level of fibrinogen of reduced activity, is the least common of all congenital fibrinogen disorders. Case report: A 31-year-old woman was reported at the 21 weeks of gestation, suffered from genital tract bleeding and there was a history of stillbirth. Clinical examination with no pathology, however laboratory tests revealed coagulation abnormalities due to prolonged thrombin test, decreased protein S and lower fibrinogen level (70 mg/dl). Autoimmune diseases were excluded and the diagnosis was widened with rotational thromboelastometry and genetic test for hypodysfibrinogenemia. The patient was treated with fibrinogen substitution and prophylactic dose of heparin throughout pregnancy and 2 weeks following labour. At 39 week of gestation Caesarean section was done, with no complications. Results: Genetic test revealed heterozygous mutation in fibrinogen gamma gene confirming hypodysfibrinogenemia. Due to bleeding manifestation in this patient of congenital fibrinogen disorders, fibrinogen substitution was implemented with heparin as a paranticoagulant prophylaxis, what turned out to be successful and enabled the patient to maintain the pregnancy. Conclusions: As hypodysfibrinogenemia symptoms are diverse the management is difficult and each patient’s therapy should be planned separately. Pregnancy may be the first time when congenital fibrinogen disorders reveal and it is especially challenging to prevent from obstetrical complications.
    Źródło:
    OncoReview; 2021, 11, 4; 102-105
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The early Bronze Age feature from Wilczyce, site 10, Sandomierz district– An interpretation of its functioning in light of multidimensional analysis.
    Autorzy:
    Jarosz, Paweł
    Boroń, Tomasz
    Witkowska, Barbara
    Winiarska-Kabacińska, Małgorzata
    Różańska-Tuta, Zuzanna
    Skrzyński, Grzegorz
    Osypińska, Marta
    Kerneder-Gubała, Katarzyna
    Szczepanek, Anita
    Sołodko, Anna
    Włodarczak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/2085854.pdf
    Data publikacji:
    2020
    Wydawca:
    Uniwersytet Rzeszowski. Instytut Archeologii Uniwersytetu Rzeszowskiego. Muzeum Okręgowe w Rzeszowie
    Tematy:
    Mierzanowice culture
    Sandomierz Upland
    funeral rite
    settlement feature
    Opis:
    The aim of this paper is to present the multidimensional characteristics of the feature number 4 at the site in Wilczyce located on the Sandomierz Upland. During exploration of the pit rich flint material, fragments of pottery vessels and animal bones were found and just above the bottom a “deposit” involved a human skull of the young female, two cattle mandibles, a sheep/goat tibia and astragalus, a damaged cattle scapula and radius, and a polishing stone were deposited. The C14 date obtained from the tooth from the cattle jaw was 3790 ± 35 BP. Based on the shape and the size of discovered feature it is possible to classify it as a typical storage pit but presence of “deposit” enable to postulate a ritual character of assemblage that reflect some kind of burial practices of the Mierzanowice culture. Rituals in the form of interring the dead or parts of their bodies can be found also in the Unietice culture so such features may indicate the emergence of a certain supra-regional and cross-cultural trend in the early Bronze Age
    Źródło:
    Analecta Archaeologica Ressoviensia; 2020, 15; 77-102
    2084-4409
    Pojawia się w:
    Analecta Archaeologica Ressoviensia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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