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    Wyświetlanie 1-6 z 6
    Tytuł:
    Content of selected heavy metals in campus of the Kielce University of Technology
    Zawartość wybranych metali ciężkich na terenie kampusu Politechniki Świętokrzyskiej
    Autorzy:
    Widłak, Małgorzata
    Dańczuk, Magdalena
    Nowak, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/387681.pdf
    Data publikacji:
    2019
    Wydawca:
    Towarzystwo Chemii i Inżynierii Ekologicznej
    Tematy:
    heavy metals
    urban soils
    toxic effects of metals
    pH
    organic matter
    metale ciężkie
    gleby miejskie
    toksyczne oddziaływanie metali
    materia organiczna
    Opis:
    The content of heavy metals in soils is a serious problem, especially in the case of agricultural soils. Metals are entering human body not only with animal and plant products but also through the skin and by inhalation. They can cause poisoning or chronic disease of the body. The aim of the study was to assess the contamination of green areas of the Kielce University of Technology by following metals Cd, Cu, Pb, Ni, Zn and Al, due to the location of the university and its campus. The range of tests performed including pH, iodine value, organic carbon, granulometry and metal content indicate the varied and significant pollution and varying degree of soil degradation. The results of the study also show that the analysed soils are formations of equally and varigrained, sand fractions. The lead concentration has been exceeded, in relation to the standards, in the sampling areas impacted by high traffic (point No. 6 located in area of Kielce University of Technology at Millennium PP7 avenue and playgrounds for volleyball).
    Zawartość metali ciężkich w glebach jest poważnym problemem, szczególnie w przypadku gleb użytkowanych rolniczo. Metale, do organizmu człowieka przedostają się nie tylko z produktami roślinnymi i zwierzęcymi, ale również przez skórę i wdychanie. Mogą wywoływać zatrucia lub przewlekłe stany chorobowe organizmu. Celem pracy była ocena zanieczyszczenia terenów zielonych Politechniki Świętokrzyskiej metalami Cd, Cu, Pb, Ni, Zn i Al ze względu na lokalizację uczelni i jej kampusu. Wykonany zakres badań uwzględniający pH, liczbę jodową, węgiel organiczny, granulometrię i zawartość metali wskazuje na zróżnicowane i znaczące zanieczyszczenie oraz różny stopień degradacji gleby. Wyniki pokazują również, że analizowane gleby to utwory równo- i różnoziarniste, frakcje piaskowe. Stężenie ołowiu zostało przekroczone, w stosunku do standardów, w miejscach o dużym oddziaływaniu ruchu samochodowego (punkt nr 6 zlokalizowany na terenach Politechniki Świętokrzyskiej oraz boiska do piłki siatkowej).
    Źródło:
    Ecological Chemistry and Engineering. A; 2019, 26, 1-2; 137-149
    1898-6188
    2084-4530
    Pojawia się w:
    Ecological Chemistry and Engineering. A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Application of Remote Sensing Techniques and Spectral Analyzes to Assess the Content of Heavy Metals in Soil – A Case Study of Barania Góra Reserve, Poland
    Autorzy:
    Sobura, Szymon
    Widłak, Małgorzata
    Hejmanowska, Beata
    Muszyńska, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/2174645.pdf
    Data publikacji:
    2022
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
    Tematy:
    remote sensing
    heavy metals
    Sentinel-2
    soil
    spectral indices
    Opis:
    The understanding of the spatial and temporal dynamics of farmland processes is essential to ensure the proper crop monitoring and early decision making needed to support efficient resource management in agriculture. By creating appropriate crop management strategies, one can increase harvest efficiency while reducing costs, waste, chemical spraying, and inhibiting the impact of biotic and abiotic factors on crop stress. Only reliable spatial information makes it possible to comprehend the influence of various factors on the environment. The main objective of the research presented in the paper was to assess the possibility of using maps of vegetation and soil indices, such as NDVI, SAVI, IRECI, CIred-edge, PSRI and HMSSI, calculated on the basis of images from the Sentinel-2 satellite, to qualitatively determine the increased amount of heavy metals in the soil in the areas of small agricultural plots around the Barania Góra nature reserve in Poland. The conducted pilot project shows that the spectral indices: NDVI, SAVI, IRECI, CIred-edge, PSRI, and HMSSI, calculated on the basis of images from Sentinel-2, have the potential to assess the content of nickel zinc, chromium and cobalt in the soil on agricultural plots. However, the confirmation of the obtained results requires continuation of the research.
    Źródło:
    Geomatics and Environmental Engineering; 2022, 16, 4; 187--213
    1898-1135
    Pojawia się w:
    Geomatics and Environmental Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ionizing radiation affects protein composition of exosomes secreted in vitro from head and neck squamous cell carcinoma
    Autorzy:
    Jelonek, Karol
    Wojakowska, Anna
    Marczak, Lukasz
    Muer, Annika
    Tinhofer-Keilholz, Ingeborg
    Lysek-Gladysinska, Malgorzata
    Widlak, Piotr
    Pietrowska, Monika
    Powiązania:
    https://bibliotekanauki.pl/articles/1039103.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    exosomes
    head and neck cancer
    ionizing radiation
    proteome
    radiobiology
    Opis:
    Exosomes are membrane vesicles of endocytic origin that participate in inter-cellular communication. Environmental and physiological conditions affect composition of secreted exosomes, their abundance and potential influence on recipient cells. Here, we analyzed protein component of exosomes released in vitro from cells exposed to ionizing radiation (2Gy dose) and compared their content with composition of exosomes released from control not irradiated cells. Exosomes secreted from FaDu cells originating from human squamous head and neck cell carcinoma were analyzed using LC-MS/MS approach. We have found that exposure to ionizing radiation resulted in gross changes in exosomal cargo. There were 217 proteins identified in exosomes from control cells and 384 proteins identified in exosomes from irradiated cells, including 148 "common" proteins, 236 proteins detected specifically after irradiation and 69 proteins not detected after irradiation. Among proteins specifically overrepresented in exosomes from irradiated cells were those involved in transcription, translation, protein turnover, cell division and cell signaling. This indicated that exosomal cargo reflected radiation-induced changes in cellular processes like transient suppression of transcription and translation or stress-induced signaling.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 2; 265-272
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Panel of serum metabolites discriminates cancer patients and healthy participants of lung cancer screening - a pilot study
    Autorzy:
    Roś-Mazurczyk, Małgorzata
    Wojakowska, Anna
    Marczak, Łukasz
    Polański, Krzysztof
    Pietrowska, Monika
    Polanska, Joanna
    Dziadziuszko, Rafał
    Jassem, Jacek
    Rzyman, Witold
    Widlak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1038611.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    early detection
    lung cancer screening
    metabolomics
    serum biomarkers
    Opis:
    Introduction. Blood biomarkers may support early diagnosis of lung cancer by enabling pre-selection of candidates for computed tomography screening or discrimination between benign and malignant screening-detected nodules. We aimed to identify features of serum metabolome distinguishing individuals with early-detected lung cancer from healthy participants of the lung cancer screening program. Methods. Blood samples were collected in the course of a low-dose computed tomography screening program performed in the Gdansk district (Northern Poland). The analysis included 31 patients with screening-detected lung cancer and the pair-matched group of 92 healthy controls. The gas chromatography coupled to mass spectrometry (GC/MS) approach was used to identify and quantify small metabolites present in serum. Results. There were several metabolites detected in the sera whose abundances discriminated patients with lung cancer from controls. Majority of the differentiating components were downregulated in cancer samples, including amino acids, carboxylic acids and tocopherols, whereas benzaldehyde was the only compound significantly upregulated. A classifier including nine serum metabolites allowed separation of cancer and control samples with 100% sensitivity and 95% specificity. Conclusions. Signature of serum metabolites discriminating between cancer patients and healthy participants of the early lung cancer screening program was identified using a GC/MS metabolomics approach. This signature, though not validated in an independent dataset, deserves further investigation in a larger cohort study.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 3; 513-518
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ionizing radiation affects profile of serum metabolites: increased level of 3-hydroxybutyric acid in serum of cancer patients treated with radiotherapy
    Autorzy:
    Roś-Mazurczyk, Małgorzata
    Wojakowska, Anna
    Marczak, Łukasz
    Polański, Krzysztof
    Pietrowska, Monika
    Jelonek, Karol
    Domińczyk, Iwona
    Hajduk, Agata
    Rutkowski, Tomasz
    Składowski, Krzysztof
    Widłak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1038706.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    head and neck cancer
    mass spectrometry
    metabolomics
    radiation response
    serum metabolome
    Opis:
    Radiotherapy causes molecular changes observed at the level of body fluids, which are potential biomarker candidates for assessment of radiation exposure. Here we analyzed radiotherapy-induced changes in a profile of small metabolites detected in sera of head and neck cancer patients using the gas chromatography coupled with mass spectrometry approach. There were about 20 compounds, including carboxylic acids, sugars, amines and amino acids, whose levels significantly differed between pre-treatment and post-treatment samples. Among metabolites upregulated by radiotherapy there was 3-hydroxybutyric acid, whose level increased about three times in post-treatment samples. Moreover, compounds affected by irradiation were associated with several metabolic pathways, including protein biosynthesis and amino acid metabolism.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 1; 189-193
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Identification of serum proteome components associated with progression of non-small cell lung cancer
    Autorzy:
    Pietrowska, Monika
    Jelonek, Karol
    Michalak, Malwina
    Roś, Małgorzata
    Rodziewicz, Paweł
    Chmielewska, Klaudia
    Polański, Krzysztof
    Polańska, Joanna
    Gdowicz-Kłosok, Agnieszka
    Giglok, Monika
    Suwiński, Rafał
    Tarnawski, Rafał
    Dziadziuszko, Rafał
    Rzyman, Witold
    Widłak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1039297.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cancer staging
    early detection
    lung cancer
    proteomics
    serum biomarkers
    Opis:
    The aim of the present study was to perform comparative analysis of serum from patients with different stages of non-small cell lung cancer (NSCLC) using the three complementary proteomic approaches to identify proteome components associated with the progression of cancer. Serum samples were collected before any treatment from 200 patients with NSCLC, including 103 early stage, 64 locally advanced and 33 metastatic cancer samples, and from 200 donors without malignancy. The low-molecular-weight fraction of serum proteome was MALDI-profiled in all samples. Serum proteins were characterized using 2D-PAGE and LC-MS/MS approaches in a representative group of 30 donors. Several significant differences were detected between serum samples collected from patients with early stage cancer and patients with locally advanced cancer, as well as between patients with metastatic cancer and patients with local disease. Of note, serum components discriminating samples from early stage cancer and healthy persons were also detected. In general, about 70 differentiating serum proteins were identified, including inflammatory and acute phase proteins already reported to be associated with the progression of lung cancer (serum amyloid A or haptoglobin). Several differentiating proteins, including apolipoprotein H or apolipoprotein A1, were not previously associated with NSCLC. No significant differences in patterns of serum proteome components were detected between patients with adenocarcinoma and squamous cell carcinoma. In conclusion, we identified the biomarker candidates with potential importance for molecular proteomic staging of NSCLC. Additionally, several serum proteome components revealed their potential applicability in early detection of the lung cancer.
    Źródło:
    Acta Biochimica Polonica; 2014, 61, 2; 325-331
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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