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Tytuł:
MGF360-12L of ASFV-SY18 is an immune-evasion protein that inhibits host type I IFN, NF-κB, and JAK/STAT pathways
Autorzy:
Chen, Q.
Wang, X.X.
Jiang, S.W.
Gao, X.T.
Huang, S.Y.
Liang, Y.
Jia, H.
Zhu, H.F.
Powiązania:
https://bibliotekanauki.pl/articles/16647496.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
African swine fever virus
MGF360-12L
type I IFN
NF-κB
JAK/STAT
Opis:
African swine fever virus (ASFV) causes feverous and hemorrhagic disease of domestic pigs and European wild boars with high mortality, yet no commercial vaccine is currently available. Several ASFV strains with natural deletion or gene-targeted knockout of multiple MGF360 and MGF505 genes are attenuated in vitro and in vivo, and can offer full protection against homologous challenge. However, the mechanisms underlying the protection are not fully understood. This study aims to investigate the effects of MGF360-12L of ASFV-SY18 on the cGAS-STING signaling pathway and explore the potential mechanisms. We identified that ASFV-SY18 MGF360-12L could inhibit cGAS-STING, TBK1, or IRF3-5D-stimulated IFN-β expression and ISRE activation. Specifically, MGF360-12L inhibits both the activation of PRD(III-I) in a dose-dependent manner, and suppresses the exogenous expression of TBK1 and IRF3-5D. MGF360-12L could block NF-κB activation induced by overexpression of cGAS-STING, TBK1, IKKβ. Downstream of the IFN-β signaling, MGF360-12L blocks the ISRE promoter activation by reducing total protein level of IRF9. Moreover, MGF360-12L protein can inhibit IFN-β-mediated antiviral effects. In conclusion, our findings suggest that MGF360-12L is a multifunctional immune-evasion protein that inhibits both the expression and effect of IFN-β, which could partially explain the attenuation of relevant gene-deleted ASFV strains, and shed light on the development of efficient ASFV live attenuated vaccines in the future.
Źródło:
Polish Journal of Veterinary Sciences; 2023, 26, 1; 119-130
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Modeling and experimental investigation of a controllable rotary fluid damper
Autorzy:
Cao, X.
Zhou, J.
Yu, M.
Wang, Y.
Powiązania:
https://bibliotekanauki.pl/articles/38697102.pdf
Data publikacji:
2023
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
controllable damper
rotary damper
parametric modeling
sensitivity analysis
damper design
Opis:
Controllable rotary fluid damper (CRFD) is an efficient and cheap energy dissipation device, which is used to reduce the impact of vibration in mechanical systems. In this paper, the CRFD controlled by a servo motor is developed to reduce the effects of vibrations in the helicopter flight control system. The dynamic mechanical characteristic of the CRFD is experimentally investigated by the MTS machine. Due to the complex factors such as high shear thinning rate and compressibility of the damping medium, inertia of moving parts and internal friction, the CRFD studied has highly nonlinear hysteresis characteristics. The accuracy of the damper modeling is of great significance for designing effective vibration reduction methods. Therefore, a new generalized viscous–nonlinear elastic model is proposed to track the mechanical characteristics of CRFD. On the basis of parameter sensitivity analysis, the proposed generalized viscous–nonlinear elastic model is modified. According to the identification results of the modified model, the main parameters are fitted as polynomial functions of motor rotation angle. Through error analysis between analytical torques and experimental torques, it is concluded that the modified generalized viscous–nonlinear elastic model has the smallest error compared with Kwok and Maxwell models, which indicates that the proposed modified model can accurately describe the mechanical characteristics of the CRFD under different working conditions.
Źródło:
Archives of Mechanics; 2023, 75, 4; 493-516
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Piezoelectric effect on thermoelastic Lamb waves in functionally graded plates
Autorzy:
Wang, X.
Ren, X.
Yu, J.
Zhou, H.
Zhang, X.
Leng, J
Powiązania:
https://bibliotekanauki.pl/articles/38695708.pdf
Data publikacji:
2023
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
thermoelastic wave
attenuation
FGM
piezoelectric effect
physical field distributions
Opis:
Based on the Lord–Shulman thermoelectric elasticity theory, the piezoelectric effect on the thermoelastic Lamb wave propagation in the functionally graded material (FGM) plate is investigated. The coupled wave equations are solved by employing the Legendre polynomial series approach (LSPA), which poses the advantages of small scale of eigenvalues matrix and a convenient solution. It can directly obtain the complex wave number solutions without iteration. The obtained complex solutions, which represent the wave propagation and attenuation, are compared with those available data. Numerical examples show that the influence of gradient is profound. Results indicate that the piezoelectric effects on attenuation with the open and closed circuit condition are consistent for the S0 and S1 modes, but are inconsistent for the A0 and A1 modes. Although the piezoelectric effect is weak on the dispersion and attenuation of thermal waves, it is notable for their physical field distributions. In addition, the relaxation time is critical to electric displacements of a thermal wave mode, but is not essential for those of Lamb-like modes. The results can be used for the optimization of thermo-electric-elastic coupling structures.
Źródło:
Archives of Mechanics; 2023, 75, 1-2; 3-26
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Shear properties of a honeycomb structure with zero Poisson’s ratio
Autorzy:
Song, L.
Sun, Y.
Han, Z.
Wang, T.
Wang, H.
Yin, C.
Shen, X.
Powiązania:
https://bibliotekanauki.pl/articles/38697109.pdf
Data publikacji:
2023
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
honeycomb structure
zero Poisson’s ratio
shear properties
small deformation
large deformation
Opis:
Honeycomb structures with zero Poisson’s ratio show promising potential for application in variable-sweep wing aircraft. The shear properties of these honeycomb structures serve as a crucial indicator of their morphing capacity. This paper derives the linear and non-linear shear properties of a honeycomb structure with zero Poisson’s ratio. A modified factor is introduced to establish a relationship between the linear and non-linear shear modulus of the honeycomb structure, simplifying the calculation method of the non-linear shear modulus. The validity of theoretical predictions is then confirmed using the finite element method Furthermore, the influences of the geometric parameters on the shear properties of the honeycomb structure with zero Poisson’s ratio are investigated, highlighting the varying contributions of these cell geometric parameters to the shear properties.
Źródło:
Archives of Mechanics; 2023, 75, 5; 521-541
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of organic supplementation to reduced rates of chemical fertilization on soil fertility of Zanthoxylum armatum
Autorzy:
Saba, T.
Liu, W.
Wang, J.
Saleem, F.
Kang, X.
Hui, W.
Gong, W.
Li, H.
Powiązania:
https://bibliotekanauki.pl/articles/2130175.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
fertilization
soil fertility
nutrient availability
organic manure
culturable microbes
Opis:
Soil acidification, fertility depletion, food insecurity, and environmental pollution all are consequences of the extensive use of chemical fertilizers (CF) in intensively managed plantations. Recent studies have shown that incorporating organic manure (OM) to partially replace CF can help to maintain productivity and soil health. There are no reports on integrated fertilizer management of Zanthoxylum armatum, for optimal ecological services and economic profitability. A pot experiment with Z. armatum was performed to investigate the possibility of incorporating OM in reducing CF use, enhancing soil fertility, and increasing plant growth. For this, seven treatments were designed: NPK, PK, NP, NK, OM, MNPK (50%NPK+50%OM), and control (CK, no fertilizer application). The results showed that NPK application significantly (P < 0.05) increased plant growth, soil nitrate-N, ammonium-N and available K compared to CK. However conventional CF application induced soil acidification. OM application raised the soil pH from 5.50 (CK) to 6.58 and significantly enhanced soil fertility by increasing alkali-hydrolysable N (2.3 times), ammonium-N (1.4 times), available P (4.3 times), the activity of invertase (1.5 times), catalase (2.8 times), acid phosphatase (1.5 times), and count of soil culturable microbes (2.9 times) compared to CK. Conversely, sole OM application did not result in optimum plant growth. Integrating OM with NPK (MNPK), on the other hand, not only provided the highest growth comprehensive value (0.84), but also substantially higher soil fertility comprehensive value (0.71) than traditional CF treatments. Correlation analysis also indicated a positive and significant correlation between soil microbes, enzyme activities and available nutrients. Therefore, OM+NPK could be an optimum measure to get maximum benefits regarding soil fertility, growth of Z. armatum, fertilizer savings and sustainable agroecology.
Źródło:
Dendrobiology; 2022, 87; 123-136
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular phylogeny of Populus (Salicaceae, Salicales) with focus on inter- and intrasectional relationships
Autorzy:
Du, S.
Hu, X.
Yang, Y.
Wang, Z.
Powiązania:
https://bibliotekanauki.pl/articles/2130215.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Instytut Dendrologii PAN
Tematy:
molecular phylogeny
section Populus
section Tacamahaca
section Aigeiros
Opis:
The relationships among sections and species within each section in the genus Populus have attracted much attention from taxonomists and biologists. In this paper, we provide an overview of the current state of Populus phylogenetics and discuss the origin of some hybrid species. There has been some controversy surrounding the origin of the genus Populus in North America and subsequent dispersal and differentiation in other parts of the world. We present the most plausible scenario based on phylogenetic analysis and fossil records. Sections Abaso, Turanga and Populus are all monophyletic, whereas sections Aigeiros, Tacamahaca and Leucoidesshow some degree of polyphyly. Sections Abaso and Turanga are relatively primitive lineages in Populus. With the accumulation of sequencing data and new analytical tools, it will be possible to investigate more complicated issues concerning genus Populus within a phylogenetic framework.
Źródło:
Dendrobiology; 2022, 88; 56-69
1641-1307
Pojawia się w:
Dendrobiology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Peridynamic analysis of 2-dimensional deformation and fracture based on an improved technique of exerting traction on boundary surface
Autorzy:
Zhou, Z.
Yu, M.
Wang, X.
Huang, Z.
Powiązania:
https://bibliotekanauki.pl/articles/38695705.pdf
Data publikacji:
2022
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
peridynamics
peridynamic motion equation
adaptive dynamic relaxation
traction boundary conditions
Opis:
For 2-dimensional problems in peridynamics, the transfer functions of boundary traction are constructed. The peridynamic motion equation introducing the boundary traction is improved and used to solve some typical 2-dimensional deformation and fracture problems, including the uniaxial tension and pure bending of plate, and fracture of a plate with the small circular hole or central crack. The acquired numerical solutions are close to the analytical solutions of elasticity and numerical solutions given by the finite element method. The results show that the improved technique of exerting traction on a boundary surface is valid for calculating the deformation and failure of solid. It provides a new method and path for the analysis of traction boundary value problems in peridynamics.
Źródło:
Archives of Mechanics; 2022, 74, 6; 441-461
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Rapid screening of monoclonal antibodies against porcine circovirus type 2 using colloidal gold-based paper test
Autorzy:
Jin, Q.Y.
Feng, L.L.
Wang, Y.B.
Li, P.
Yang, J.F.
Teng, M.
Chai, S.J.
Xing, G.X.
Zhang, G.P.
Powiązania:
https://bibliotekanauki.pl/articles/16539073.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
porcine circovirus type 2 (PCV2)
screening of MAbs
paper test
Opis:
A proof of concept for using paper test as a suitable method in the production of monoclonal antibodies (MAbs) is reported. The paper test which detects antibodies against porcine circovirus type 2 (PCV2) using colloidal gold-labelled capsid protein as the antigen probe was applied exclusively in the screening of anti-PCV2 MAbs. It allowed the detection of 118 single cell clones within 30 min using naked eyes. MAbs with specific binding to authentic epitopes on the virus were selected using a blocking strategy in which the antibody was pre-incubated with PCV2 viral sample before applying to the test paper. Five hybridomas secreting MAbs against the capsid protein were obtained, with only three of them capable of binding to PCV2. The results were validated and confirmed using enzyme-linked immunosorbent assay and immunofluorescence assay. The paper test is simple, rapid, and independent on professional technicians and proves to be an excellent approach for the screening of MAbs against specific targets.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 1; 27-34
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Uniformity of electroelastic field within a three-phase anisotropic piezoelectric elliptical inhomogeneity in anti-plane shear
Autorzy:
Wang, X.
Schiavone, P.
Powiązania:
https://bibliotekanauki.pl/articles/38694715.pdf
Data publikacji:
2022
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
three-phase elliptical inhomogeneity
confocal ellipses
monoclinic piezoelectric material
transversely isotropic piezoelectric material
Stroh quartic formalism
real-form solution
Opis:
Using the Stroh quartic formalism, we prove that the internal electroelastic field is unconditionally uniform inside a three-phase anisotropic piezoelectric elliptical inhomogeneity with two confocal elliptical interfaces when the surrounding matrix is subjected to uniform remote anti-plane mechanical and in-plane electrical loading. The inhomogeneity and the matrix comprise monoclinic piezoelectric materials with symmetry plane at x3 = 0 and with poling in the x3-direction; the intermediate interphase layer is a transversely isotropic piezoelectric material with poling in the x3-direction. Moreover, we obtain the internal uniform electroelastic field inside the elliptical inhomogeneity and the non-uniform electroelastic field in the interphase layer in real-form in terms of the fundamental piezoelectricity matrices for both the inhomogeneity and the matrix and the generalized Barnett–Lothe tensors for both the interphase layer and the matrix.
Źródło:
Archives of Mechanics; 2022, 74, 2-3; 143-156
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A screw dislocation located outside, inside or on the interface of a parabolic elastic inhomogeneity
Autorzy:
Wang, X.
Schiavone, P.
Powiązania:
https://bibliotekanauki.pl/articles/38627364.pdf
Data publikacji:
2021
Wydawca:
Instytut Podstawowych Problemów Techniki PAN
Tematy:
screw dislocation
parabolic elastic inhomogeneity
superposition
conformal mapping
analytic continuation
Opis:
Using conformal mapping techniques, superposition and analytic continuation, we derive analytic solutions to the problem of a screw dislocation interacting with a parabolic elastic inhomogeneity. The screw dislocation can be located anywhere either in the surrounding matrix or in the parabolic inhomogeneity or simply on the parabolic interface itself. We obtain explicit expressions for the two analytic functions in the image plane characterizing the elastic fields describing displacement and stresses in the two-phase composite. Using the Peach-Koehler formula, we also obtain the image force acting on the screw dislocation. The analytic function defined in the parabolic inhomogeneity in the physical plane can be interpreted in terms of real and image screw dislocations for any location of the real screw dislocation.
Źródło:
Archives of Mechanics; 2021, 73, 3; 219-235
0373-2029
Pojawia się w:
Archives of Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibacterial spectrum of four compounds from yeasts in koumiss
Autorzy:
Chen, Y.J.
Du, C.G.
Guo, Y.Q.
Zhao, Y.F.
Aorigele, C.
Wang, C.J.
Simujide, H.
Aqima, W.
Zhang, X.Y.
Powiązania:
https://bibliotekanauki.pl/articles/2087160.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Kluyveromyces marxianus
Saccharomyces cerevisiae
Escherichia coli
minimum inhibition concentration
minimum bactericidal concentration
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 2; 167-173
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibiofilm activity against Staphylococcus aureus and content analysis of Taraxacum Officinale phenolic extract
Autorzy:
Xu, P.
Xu, X.B.
Khan, A.
Fotina, T.
Wang, S.H.
Powiązania:
https://bibliotekanauki.pl/articles/2087162.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Taraxacum Officinale
phenolic
antibacterial mechanism
HPLC
Staphylococcus aureus
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 2; 243-251
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Development of a SYBR Green I real-time PCR assay for detection of novel porcine parvovirus 7
Autorzy:
Li, Y.D.
Yu, Z.D.
Bai, C.X.
Zhang, D.
Sun, P.
Peng, M.L
Liu, H.
Wang, J.
Wang, Y.
Powiązania:
https://bibliotekanauki.pl/articles/2087207.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Capsid gene
PPV7
SYBR Green I real-time PCR
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 1; 43-49
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fatigue life prediction for Ni-based superalloy GH4169 considering machined surface roughness and residual stress effects
Autorzy:
Wu, Z. R.
Wang, S. Q.
Yang, X.
Pan, L.
Song, Y. D.
Powiązania:
https://bibliotekanauki.pl/articles/1839712.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
surface roughness
residual stress
fatigue crack
life prediction
GH4169
Opis:
Establishing a fatigue life prediction model considering the machined surface state is of great significance to improve fatigue life prediction accuracy. Fatigue tests with different machined surface states of GH4169 alloy were conducted firstly. The influence of surface state parameters on the fatigue life was analyzed. Then, the machined surface stress concentration factor and residual stress were introduced into the fatigue crack initiation and propagation models. Finally, the fatigue life prediction model of GH4169 material considering the surface states was established. The prediction results based on the proposed model are almost within a factor of two scatter band of the test results.
Źródło:
Journal of Theoretical and Applied Mechanics; 2021, 59, 2; 215-226
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Genetic analysis of 38 double-flowered amaryllis (Hippeastrum hybridum) cultivars based on SRAP markers
Autorzy:
Xiong, M.
Yang, S.
Wang, Y.
Chen, D.
Wang, X.
Zhou, D.
Wei, Z.
Powiązania:
https://bibliotekanauki.pl/articles/12994499.pdf
Data publikacji:
2021
Wydawca:
Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
Źródło:
Acta Scientiarum Polonorum. Hortorum Cultus; 2021, 20, 3; 15-25
1644-0692
Pojawia się w:
Acta Scientiarum Polonorum. Hortorum Cultus
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 261

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