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Wyszukujesz frazę "Wąsowicz, Michał" wg kryterium: Autor


Wyświetlanie 1-3 z 3
Tytuł:
Machine learning system for automated blood smear analysis
Autorzy:
Grochowski, Michał
Wąsowicz, Michał
Mikołajczyk, Agnieszka
Ficek, Mateusz
Kulka, Marek
Wróbel, Maciej S.
Jędrzejewska-Szczerska, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/220750.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
optical microscopy
blood cells
biophotonics
image analysis
classification
eigenfaces
neural networks
decision support
nanodiamonds
bioimaging
Opis:
In this paper the authors propose a decision support system for automatic blood smear analysis based onmicroscopic images. The images are pre-processed in order to remove irrelevant elements and to enhancethe most important ones – the healthy blood cells (erythrocytes) and the pathologic ones (echinocytes). The separated blood cells are analysed in terms of their most important features by the eigenfaces method. The features are the basis for designing the neural network classifier, learned to distinguish between erythrocytes and echinocytes. As the result, the proposed system is able to analyse the smear blood images in a fully automatic way and to deliver information on the number and statistics of the red blood cells, both healthy and pathologic. The system was examined in two case studies, involving the canine and human blood, and then consulted with the experienced medicine specialists. The accuracy of classification of red blood cells into erythrocytes and echinocytes reaches 96%.
Źródło:
Metrology and Measurement Systems; 2019, 26, 1; 81-93
0860-8229
Pojawia się w:
Metrology and Measurement Systems
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Liber Copulatorum z parafii Kaława z XVII-XVIII w. Edycja źródłowa
Liber Copulatorum from the parish of Kaława of the 17th and 18th centuries. A source edition
Autorzy:
Sołomieniuk, Michał
Wąsowicz, Jarosław
Powiązania:
https://bibliotekanauki.pl/articles/2035014.pdf
Data publikacji:
2019
Wydawca:
Agencja Wydawnicza “PDN”
Tematy:
Kaława
Liber Copulatorum z Kaławy
metrykalia
Opis:
The history of the parish in Kaława is connected with the history of the Cistercian monastery in Paradyż. In the second half of the 13th century, the church dedicated to St Nicolaus was built in this village; for the first time this church is mentioned in Liber beneficiorum of 1510. It is probable that it was then that the parish was established. In the Reformation period, the church along with the parish was taken over by Protestants; however, in 1596 it was returned to Catholics. From then onwards, the Cistercians from Paradyż were parish priests in this parish. During the Thirty Years’ War (1618-1648), the Brandenburg and Swedish armies invaded the abbey and its villages. During the Swedish Deluge in 1655, the church in Kaława was looted and burnt. At the request of the then Paradyż Abbot Edmund Zagorow, the church was rebuilt and opened for the faithful in 1660. However, this church was also destroyed in a fire in 1733. It was rebuilt again by Abbot Józef Gorczyński. The presented Liber Copulatorum of the years 1689-1759 is the oldest surviving parish book in the archive of the parish in Kaława; it is included in the folder ‘The fragments of the old registers of the parish of Kaława’. The publishers hope this edition will contribute to further research on the history of the Catholic parishes in the deanery of Pszczew in the early modern times and the history of the Cistercian abbey in Paradyż.
Źródło:
Adhibenda; 2019, 6; 163-178
2391-6109
Pojawia się w:
Adhibenda
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The ESR1 and GPX1 gene expression level in human malignant and non-malignant breast tissues
Autorzy:
Król, Magdalena
Galicki, Michał
Grešner, Peter
Wieczorek, Edyta
Jabłońska, Ewa
Reszka, Edyta
Morawiec, Zbigniew
Wąsowicz, Wojciech
Gromadzińska, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/1038523.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
estrogen receptor
antioxidant enzymes
gene expression
breast cancer tissue
Opis:
Background: The aim of this study was to establish whether the gene expression of estrogen receptor alpha (encoded by ESR1) correlates with the expression of glutathione peroxidase 1 (encoded by GPX1) in the tumor and adjacent tumor-free breast tissue, and whether this correlation is affected by breast cancer. Such relationships may give further insights into breast cancer pathology with respect to the status of estrogen receptor. Methods: We used the quantitative real-time PCR technique to analyze differences in the expression levels of the ESR1 and GPX1 genes in paired malignant and non-malignant tissues from breast cancer patients. Results: ESR1 and GPX1 expression levels were found to be significantly down-regulated by 14.7% and 7.4% (respectively) in the tumorous breast tissue when compared to the non-malignant one. Down-regulation of these genes was independent of the tumor histopathology classification and clinicopathological factors, while the ESR1 mRNA level was reduced with increasing tumor grade (G1: 103% vs. G2: 85.8% vs. G3: 84.5%; p<0.05). In the non-malignant and malignant breast tissues, the expression levels of ESR1 and GPX1 were significantly correlated with each other (Rs=0.450 and Rs=0.360; respectively). Conclusion: Our data suggest that down-regulation of ESR1 and GPX1 was independent of clinicopathological factors. Down-regulation of ESR1 gene expression was enhanced by the development of the disease. Moreover, GPX1 and ESR1 gene expression was interdependent in the malignant breast tissue and further work is needed to determine the mechanism underlying this relationship.
Źródło:
Acta Biochimica Polonica; 2018, 65, 1; 51-57
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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