- Tytuł:
- The polar profile of ancient proteins: a computational extrapolation from prebiotics to paleobiochemistry
- Autorzy:
-
Polanco, Carlos
Buhse, Thomas
Vizcaíno, Gloria
Picciotto, Jacobo - Powiązania:
- https://bibliotekanauki.pl/articles/1038695.pdf
- Data publikacji:
- 2017
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
origins of life
prebiotic protein formation
abiogenesis - Opis:
- This paper addresses the polar profile of ancient proteins using a comparative study of amino acids found in 25 000 000-year-old shells described in Abelson's work. We simulated the polar profile with a computer platform that represented an evolutionary computational toy model that mimicked the generation of small proteins starting from a pool of monomeric amino acids and that included several dynamic properties, such as self-replication and fragmentation-recombination of the proteins. The simulations were taken up to 15 generations and produced a considerable number of proteins of 25 amino acids in length. The computational model included the amino acids found in the ancient shells, the thermal degradation factor, and the relative abundance of the amino acids observed in the Miller-Urey experimental simulation of the prebiotic amino acid formation. We found that the amino acid polar profiles of the ancient shells and those simulated and extrapolated from the Miller-Urey abundances are coincident.
- Źródło:
-
Acta Biochimica Polonica; 2017, 64, 1; 117-122
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł