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Wyszukujesz frazę "Tan, Y." wg kryterium: Autor


Tytuł:
Time-varying time-delay estimation for nonlinear systems using neural networks
Autorzy:
Tan, Y.
Powiązania:
https://bibliotekanauki.pl/articles/907277.pdf
Data publikacji:
2004
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
modelowanie procesu
opóźnienie czasowe
układ nieliniowy
sieć neuronowa
modelling
time delay
nonlinear systems
neural networks
estimation
Opis:
Nonlinear dynamic processes with time-varying time delays can often be encountered in industry. Time-delay estimation for nonlinear dynamic systems with time-varying time delays is an important issue for system identification. In order to estimate the dynamics of a process, a dynamic neural network with an external recurrent structure is applied in the modeling procedure. In the case where a delay is time varying, a useful way is to develop on-line time-delay estimation mechanisms to track the time-delay variation. In this paper, two schemes called direct and indirect time-delay estimators are proposed. The indirect time-delay estimator considers the procedure of time-delay estimation as a nonlinear programming problem. On the other hand, the direct time-delay estimation scheme applies a neural network to construct a time-delay estimator to track the time-varying time-delay. Finally, a numerical example is considered for testing the proposed methods.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2004, 14, 1; 63-68
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Frothers and gas dispersion: A review of the structure-property-function relationship
Autorzy:
Tan, Y. H.
Finch, J. A.
Powiązania:
https://bibliotekanauki.pl/articles/109942.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
frothers
alcohols
polyglycols
frother structure
mechanisms
Opis:
Over the past 20 years quantitative measures of frother functions have been developed to try to replace such qualitative descriptors as “weak” and “strong”. One of these metrics is the critical coalescence concentration (CCC) that quantifies a frother’s ability to reduce bubble size; another is the concentration at minimum velocity (CMV) that quantifies a frother’s ability to reduce bubble rise velocity. The experimental procedure for the two measures is briefly outlined and the measures are shown to be related. Using CMV, based on more than 50 surfactants from the two main frother families, alcohols and polyglycols, the frother structure-property-function link is investigated. The structure variables were: in alcohols, alkyl chain length, and position of the methyl branch and hydroxyl group(s); and in polyglycols, alkyl chain length, and number of propylene oxide (PO) or ethylene oxide (EO) groups. On the argument that low CMV represents the desired outcome, the main findings are: the dominant effect of alkyl chain length in both alcohols and polyglycols; that for alcohols branched-chain isomers are superior to straight chain, with the best combination being OH at the terminus and the methyl branch as far away as possible; and for polyglycols, PO-based are superior to EO-based. Interpretation of these observations included the effect of structure on the following properties: surface activity, mass transfer rate, H-bonding, and molecule packing.
Źródło:
Physicochemical Problems of Mineral Processing; 2018, 54, 1; 40-53
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Recursive identification algorithm for dynamic systems with output backlash and its convergence
Autorzy:
Dong, R.
Tan, Q.
Tan, Y.
Powiązania:
https://bibliotekanauki.pl/articles/930007.pdf
Data publikacji:
2009
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
system nieliniowy
luz
identyfikacja rekurencyjna
nonlinear system
backlash
recursive identification
pseudo-Wiener model
Opis:
This paper proposes a recursive identification method for systems with output backlash that can be described by a pseudo-Wiener model. In this method, a novel description of the nonlinear part of the system, i.e., backlash, is developed. In this case, the nonlinear system is decomposed into a piecewise linearized model. Then, a modified recursive general identification algorithm (MRGIA) is employed to estimate the parameters of the proposed model. Furthermore, the convergence of the MRGIA for the pseudo-Wiener system with backlash is analysed. Finally, a numerical example is presented.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2009, 19, 4; 631-638
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Observability and controllability analysis for sandwich systems with backlash
Autorzy:
Luo, N.
Tan, Y.
Dong, R.
Powiązania:
https://bibliotekanauki.pl/articles/330501.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
backlash
sandwich system
non smooth system
state space equation
observability
controllability
luz mechaniczny
układ warstwowy
równanie stanu
obserwowalność
sterowalność
Opis:
In this paper, an approach to analyze the observability and controllability of sandwich systems with backlash is proposed. In this method, a non-smooth state-space function is used to describe the sandwich systems with backlash which are also non-smooth non-linear systems. Then, a linearization method based on non-smooth optimization is proposed to derive a linearized state-space function to approximate the non-smooth sandwich systems within a bounded region around the equilibrium point that we are interested in. Afterwards, both observability and controllability matrices are constructed and the methods to analyze the observability as well as controllability of sandwich system with backlash are derived. Finally, numerical examples are presented to validate the proposed method.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2015, 25, 4; 803-814
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Consistency analysis of degradation mechanism in step-stress acc elerated degradation testing
Analiza niezmienności mechanizmu degradacji w przyspieszonych badaniach degradacji z obciążeniem stopniowym
Autorzy:
Lu, X.
Chen, X.
Wang, Y.
Tan, Y.
Powiązania:
https://bibliotekanauki.pl/articles/301224.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
przyspieszone badania degradacji z obciążeniem stopniowym
niezmienność mechanizmu degradacji
test ilorazu wiarygodności
uszczelka gumowa
step-stress accelerated degradation testing
degradation mechanism consistency
likelihood ratio test
rubber seals
Opis:
Step-stress accelerated degradation testing (SSADT) has been used by many researchers for the reliability assessment of highly reliable products. Most of the previous works on SSADT assume that the degradation mechanism keeps unchanged during the accelerated degradation testing. However, some recent investigations have shown that degradation mechanisms may be different among various accelerated stress levels. For an accurate extrapolation of accelerated testing results to the ambient condition, the degradation mechanism at all accelerated stress levels should be the same. Taking the variation of the degradation mechanism into account, it is advisable to test the degradation mechanism consistency in a SSADT. This paper proposes a likelihood ratio test method for the consistency analysis of degradation mechanism in the SSADT. We first introduce the basic principle of the likelihood ratio test method. Then we describe the model for SSADT data and the parameter estimation method. Further, we propose a decision rule for the consistency analysis. The proposed method is illustrated and validated with examples on the consistency analysis of degradation mechanism in a SSADT of silicone rubbers.
Wielu badaczy wykorzystuje przyspieszone badania degradacji z obciążeniem stopniowym (ang. step-stress accelerated degradation testing, SSADT) do oceny niezawodności wysoce niezawodnych produktów. Większość wcześniejszych prac nad SSADT zakłada, że podczas badań przyspieszonych mechanizm degradacji pozostaje niezmienny. Jednak, najnowsze badania wykazały, że mechanizmy degradacji mogą różnić się w zależności od poziomu przyspieszonego obciążenia. Poprawna ekstrapolacja wyników badań przyspieszonych na warunki otoczenia wymaga aby mechanizm degradacji przy wszystkich poziomach obciążenia był taki sam. Biorąc pod uwagę zmienność mechanizmu degradacji, wskazane jest badanie stopnia (nie)zmienności mechanizmu degradacji w badaniach SSADT. W artykule zaproponowano metodę analizy niezmienności mechanizmu degradacji w badaniach SSADT opartą na teście ilorazu wiarygodności. W pierwszej kolejności, przedstawiono podstawową zasadę testu ilorazu wiarygodności. Następnie, opisano model dla danych SSADT i metodę estymacji parametrów. Ponadto zaproponowano regułę decyzyjną stanowiąca narzędzie do analizy niezmienności. Omawianą metodę zilustrowano i zweryfikowano na przykładzie analizy niezmienności mechanizmu degradacji w badaniach SSADT gumy silikonowej.
Źródło:
Eksploatacja i Niezawodność; 2017, 19, 2; 302-309
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of pH and time on hydrodynamic properties of dodecylamine
Autorzy:
Zhou, X.
Tan, Y. H.
Finch, J. A.
Powiązania:
https://bibliotekanauki.pl/articles/109853.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
pH
dodecylamine
gas holdup
froth height
Frother function
Opis:
Gas holdup and froth height in the presence of dodecylamine (DDA, pKa = 10.63) are reported at three pH values. The results revealed a strong time effect for DDA: stability was reached at pH 3; not at natural pH, for example, gas holdup declining to the water only value; and at pH 11, while stability was reached quickly gas holdup was now less than in water alone indicating coalescence. In the first two cases, the time effect is attributed to loss of amine from the system as molecular amine, observed at natural pH as precipitates on the column wall. An argument for precipitation at pH < pKa is presented. At pH 11, coalescence is attributed to the oily nature of the molecular amine present as colloidal aggregates. Noting a difference in literature steady state gas holdup data at natural pH, it is speculated that varying steady states can be reached that corresponds to different levels of amine loss.
Źródło:
Physicochemical Problems of Mineral Processing; 2018, 54, 4; 1237-1244
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lifetime prediction method for electron multiplier based on accelerated degradation test
Metoda prognozowania cyklu życia powielacza elektronów oparta na przyspieszonych badaniach degradacji
Autorzy:
Wang, Y.
Zhang, C.
Chen, X.
Tan, Y.
Powiązania:
https://bibliotekanauki.pl/articles/301960.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
electron multiplier
accelerated degradation test
lifetime prediction
reliability
powielacz elektronów
przyspieszone badanie degradacji
prognozowanie cyklu życia
niezawodność
Opis:
Electron multiplier (EM) is a kind of highly reliable and long-lifetime vacuum electronic device applied widely in spectrometry, space exploration and atom frequency standard. It is a critical device which might constrain the related technology. A challenge remains for researcher and engineer how to predict the life span of EM. Firstly, degradation mechanism of EM is investigated. It shows that the secondary emission ratios of each multiplier electrode reduces gradually with operating time, which results in the degradation of the key performance index of EM, i.e. the gain of electric current. So an accelerated degradation test (ADT) methodology using dual stresses is proposed to predict the life span of EM. Secondly, the ADT plan with dual stresses is designed and carried out by the corresponding test system established. Finally, the data analysis procedure is presented, and its validity is investigated by model verification. The presented method can sharply reduce testing time and cost because of using accelerated stress which can accelerate degradation process of EM. This method can also provide a new way to lifetime and reliability prediction for other products with long lifetime and high reliability.
Powielacz elektronów (EM) to elektroniczne urządzenie próżniowe o wysokiej niezawodności i długim cyklu życia, które znajduje szerokie zastosowanie w spektrometrii i badaniach przestrzeni kosmicznej, a także w atomowych wzorcach częstotliwości. Jest to urządzenie krytyczne, które może stanowić ograniczenie dla technologii, w której jest wykorzystywane. Wyzwaniem dla naukowców i inżynierów pozostaje pytanie, jak przewidzieć żywotność EM. W pierwszej kolejności w artykule zbadano mechanizm degradacji EM. Badanie pokazało, że współczynniki emisji wtórnej elektrody powielacza maleją stopniowo wraz z upływem czasu pracy, co prowadzi do degradacji kluczowego wskaźnika wydajności EM, to znaczy wzmocnienia prądu elektrycznego. W oparciu o ten fakt, zaproponowano metodę prognozowania żywotności EM zasadzającą się na metodologii przyspieszonych badań degradacji (ADT) z wykorzystaniem podwójnych naprężeń. Następnie zaprojektowano i zrealizowano plan ADT z podwójnymi naprężeniami za pomocą odpowiedniego systemu testowego. Na koniec przedstawiono procedurę analizy danych, a ich wiarygodność zbadano poprzez weryfikację modelu. Przedstawiona metoda może znacznie zredukować czas i koszty badań dzięki wykorzystaniu przyspieszonych naprężeń, które mogą przyspieszyć proces degradacji EM. Metoda ta może również umożliwić nowy sposób przewidywania niezawodności i cyklu życia produktów o długim cyklu życia i wysokiej niezawodności.
Źródło:
Eksploatacja i Niezawodność; 2014, 16, 3; 484-490
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neural network based identification of hysteresis in human meridian systems
Autorzy:
Tan, Y.
Dong, R.
Chen, H.
He, H.
Powiązania:
https://bibliotekanauki.pl/articles/330958.pdf
Data publikacji:
2012
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
punkt akupunktury
histereza
sieć neuronowa
tradycyjna medycyna chińska
acupuncture point
hysteresis
identification
neural network
human meridian
traditional Chinese medicine
Opis:
Developing a model based digital human meridian system is one of the interesting ways of understanding and improving acupuncture treatment, safety analysis for acupuncture operation, doctor training, or treatment scheme evaluation. In accomplishing this task, how to construct a proper model to describe the behavior of human meridian systems is one of the very important issues. From experiments, it has been found that the hysteresis phenomenon occurs in the relations between stimulation input and the corresponding response of meridian systems. Therefore, the modeling of hysteresis in a human meridian system is an unavoidable task for the construction of model based digital human meridian systems. As hysteresis is a nonsmooth, nonlinear and dynamic system with a multi-valued mapping, the conventional identification method is difficult to be employed to model its behavior directly. In this paper, a neural network based identification method of hysteresis occurring in human meridian systems is presented. In this modeling scheme, an expanded input space is constructed to transform the multi-valued mapping of hysteresis into a one-to-one mapping. For this purpose, a modified hysteretic operator is proposed to handle the extremum-missing problem. Then, based on the constructed expanded input space with the modified hysteretic operator, the so-called Extreme Learning Machine (ELM) neural network is utilized to model hysteresis inherent in human meridian systems. As hysteresis in meridian system is a dynamic system, a dynamic ELM neural network is developed. In the proposed dynamic ELMneural network, the output state of each hidden neuron is fed back to its own input to describe the dynamic behavior of hysteresis. The training of the recurrent ELM neural network is based on the least-squares algorithm with QR decomposition.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2012, 22, 3; 685-694
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Fabrication and Characterization of PMMA/HMX-based Microcapsules via in situ Polymerization
Autorzy:
Jia, X.
Hou, C.
Tan, Y.
Wang, J.
Ye, B.
Powiązania:
https://bibliotekanauki.pl/articles/358134.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
fabrication
characterization
HMX
PMMA
microcapsules
Opis:
Microcapsule technology was applied with nitramine explosives to improve their performance. Polymethyl Methacrylate (PMMA) was selected for the fabrication of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) based microcapsules. The PMMA/HMX-based microcapsules were prepared via a facile in situ polymerization of PMMA on the surface of the HMX crystals. Structural characterization of the PMMA/HMX microcapsules was studied systematically by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, and their thermal durability as well as their mechanical sensitivities were measured. The results indicated that spherical microcapsules were formed, with PMMA as the capsule wall and HMX as the core material. The SEM results showed that the grains of the PMMA/HMX microcapsules were spherical and that the particle distribution was homogeneous. XRD and FT-IR analyses indicated that the HMX polymorph was preserved in the optimal β-form during the whole preparative process. The DSC results showed that the PMMA/HMX microcapsules had better thermal decomposition performance, and that the apparent activation energy of the microcapsules had increased by 47.3 kJ/mol compared to the recrystallized HMX, and its thermal stability had greatly improved. In addition, the drop height (H50) had increased from 30.45 cm to 58.49 cm, an increase of 65.81%. Thus, microcapsule technology will have a very wide range of applications in reducing the sensitivity of high energy materials in the future.
Źródło:
Central European Journal of Energetic Materials; 2017, 14, 3; 559-572
1733-7178
Pojawia się w:
Central European Journal of Energetic Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Short-term variation in zooplankton community from Daya Bay with outbreaks of Penilia avirostris
Autorzy:
Li, K.
Yin, J.
Tan, Y.
Huang, L.
Song, X.
Powiązania:
https://bibliotekanauki.pl/articles/47644.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Instytut Oceanologii PAN
Tematy:
zooplankton
Penilia avirostris
outbreak
short-term variability
nuclear power plant
temporal variation
water temperature
salinity
chlorophyll a
aquaculture area
Daya Bay
Źródło:
Oceanologia; 2014, 56, 3
0078-3234
Pojawia się w:
Oceanologia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Potential risk of Mesodinium rubrum bloom in the aquaculture area of Dapeng’ao cove, China: diurnal changes in the ciliate community structure in the surface water
Autorzy:
Liu, H.
Song, X.
Huang, L.
Tan, Y.
Zhong, Y.
Huang, J.R.
Powiązania:
https://bibliotekanauki.pl/articles/47949.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Instytut Oceanologii PAN
Tematy:
potential risk
Mesodinium rubrum
bloom
aquaculture area
Dapeng'ao cove
China
diurnal change
ciliate community
surface water
heavy rainfall
water column
stratification
irradiance
Opis:
Diurnal changes in the structure of the ciliate community in surface waters were studied in the aquaculture area of Dapeng’ao cove, China. Two periods of heavy rainfall occurred during the study period, intensifying water column stratification and influencing the water’s properties. A total of 21 ciliate taxa from 15 genera were identified; the dominant species was Mesodinium rubrum. The maximum abundance of M. rubrum reached 3.92×104 indiv. dm−3, contributing 95.1% (mean value) to the total ciliate abundance. Diurnal changes in M. rubrum abundance were highly variable, the driving force probably being irradiance and food availability. The results suggest that M. rubrum may form blooms in aquaculture areas when there is a suitable physical regime with enriched nutrients, which is potentially harmful to the fish-farming industry.
Źródło:
Oceanologia; 2012, 54, 1
0078-3234
Pojawia się w:
Oceanologia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of gate drive circuit effect in cascode GaN-based applications
Autorzy:
Tan, Q. Y.
Narayanan, E. M. S.
Powiązania:
https://bibliotekanauki.pl/articles/2173545.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
cascode GaNFETs
parasitics
buck converter
gate drive design
kaskoda GaNFETs
przetwornica
pasożytnictwo
projekt napędu bramy
Opis:
This work evaluates the influence of gate drive circuitry to cascode GaN device’s switching waveforms. This is done by comparing three PCBs using three double-pulse-test (DPT) with different gate driving loop design. Among important parasitic elements, source-side inductance shows a significant impact to gate-source voltage waveform. A simulation model based on experimental measurement of the cascode GaNFET used in this work is modified by author. The simulation model is implemented in a synchronous buck converter topology and hereby to assess the impact of gate driving loop of cascode GaN device in both continuous conduction mode (CCM) and critical conduction mode (CRM). Apart from simulation, a synchronous buck converter prototype is presented for experimental evaluation, which shows a 99.15% efficiency at 5A under soft-switching operation (CRM) with a 59ns dead-time.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2021, 69, 2; art. no. e136742
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of gate drive circuit effect in cascode GaN-based applications
Autorzy:
Tan, Q. Y.
Narayanan, E. M. S.
Powiązania:
https://bibliotekanauki.pl/articles/2128152.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
cascode GaNFETs
parasitics
buck converter
gate drive design
kaskoda GaNFETs
przetwornica
pasożytnictwo
projekt napędu bramy
Opis:
This work evaluates the influence of gate drive circuitry to cascode GaN device’s switching waveforms. This is done by comparing three PCBs using three double-pulse-test (DPT) with different gate driving loop design. Among important parasitic elements, source-side inductance shows a significant impact to gate-source voltage waveform. A simulation model based on experimental measurement of the cascode GaNFET used in this work is modified by author. The simulation model is implemented in a synchronous buck converter topology and hereby to assess the impact of gate driving loop of cascode GaN device in both continuous conduction mode (CCM) and critical conduction mode (CRM). Apart from simulation, a synchronous buck converter prototype is presented for experimental evaluation, which shows a 99.15% efficiency at 5A under soft-switching operation (CRM) with a 59ns dead-time.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2021, 69, 2; e136742, 1--7
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Development of an indirect ELISA based on glycoprotein B gene for detecting of Feline herpesvirus type 1
Autorzy:
Tan, Y.
Dong, G.
Niu, J.
Guo, Y.
Yi, S.
Sun, M.
Wang, K.
Hu, G.
Powiązania:
https://bibliotekanauki.pl/articles/2087468.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
feline herpesvirus type 1
gB protein
indirect ELISA
prokaryotic expression
Źródło:
Polish Journal of Veterinary Sciences; 2019, 3; 631-633
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Factors influencing serum chemerin and kallistatin concentrations in patients with alcohol-induced liver cirrhosis
Autorzy:
Prystupa, A.
Kiciński, P.
Luchowska-Kocot, D.
Sak, J.
Prystupa, T.K.
Tan, Y.-H.
Panasiuk, L.
Załuska, W.
Powiązania:
https://bibliotekanauki.pl/articles/2082078.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
alcohol-induced liver cirrhosis
chemerin
kallistatin
Opis:
Introduction. In Poland, an increasing number of patients are hospitalized due to liver diseases. One of the common liver diseases is cirrhosis, which can be caused by alcohol, viral hepatitis, autoimmune processes and metabolic diseases. Materials and method. The study included 99 patients with alcoholic cirrhosis from the Lublin region of Eastern Poland. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The concentrations of serum kallistatin and chemerin were determined using ELISA kits. Objective. The aim of the study is to evaluate serum levels of kallistatin and chemerin in patients with different stages of alcoholic liver cirrhosis. Results. The highest chemerin level was found in the control group – 182.6±80.4 ng/ml. In other stages of liver cirrhosis, the following levels were observed: 175.7±62.7 ng/ml in Child-Pugh stage A (Ch-P A), 150.2±59.7 ng/ml in Ch-P B and 110.3±73.6 ng/ml in Ch-P C. Significant differences in chemerin levels between controls and Ch-P C patients (p=0.01), as well as between the Ch-P A patients and Ch-P C patients (p=0.02), were demonstrated. The highest kallistatin level was demonstrated in the control group – 8.2±3.5 μg/ml. In other stages of liver cirrhosis, the following concentrations were found: 7.2±27 μg/ml in Ch-P A, 4.4±2.2 μg/ml in Ch-P B and 3.5±1.9 μg/ml in Ch-P C (Tab. 3). Statistically significant differences were observed between controls and Ch-P B patients (p<0.001), controls and Ch-P C patients (p<0.001), Ch-P A and Ch-P B patients (p=0.01), as well as Ch-P A and Ch-P C patients (<0.001). Conclusions. The levels of chemerin and kallistatin decrease with progression of liver damage during alcoholic liver cirrhosis. The impairment of its synthetic function leads to reductions in levels of the adipokines studied.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 143-147
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł

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