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Wyszukujesz frazę "Szumiło, Maria" wg kryterium: Autor

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    Wyświetlanie 1-3 z 3
    Tytuł:
    The effects of captan and captafol on different bacterial strains and on c-mitosis in V79 Chinese hamster fibroblasts
    Autorzy:
    Rahden-Staroń, Iwonna
    Szumiło, Maria
    Ziemkiewicz, Paweł
    Powiązania:
    https://bibliotekanauki.pl/articles/1045419.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Źródło:
    Acta Biochimica Polonica; 1994, 41, 1; 45-55
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Defective Brca2 influences topoisomerase I activity in mammalian cells*.
    Autorzy:
    Rahden-Staroń, Iwonna
    Szumiło, Maria
    Grosicka, Emilia
    Kraakman - van der Zwet, Maria
    Zdzienicka, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/1043656.pdf
    Data publikacji:
    2003
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    camptothecin
    V-C8 mutant
    topoisomerase I
    Brca2 gene
    Opis:
    The Chinese hamster cell mutant V-C8 is defective in the Brca2 gene (Kraakman-van der Zwet et al., 2002, Cell Biol.; 22: 669). Here we report that V-C8 cells were 10-fold more sensitive to camptothecin, an inhibitor of topoisomerase I, than the parental V79 cells. The level of the relaxation activity of topoisomerase I in nuclear extracts was also lower (4-fold) in V-C8 than V79 cells, in spite of the fact that the level of the topoisomerase I protein was the same in these cells. The survival of V-C8 cells in the presence of camptothecin, the sensitivity of V-C8 topoisomerase I to camptothecin, and the level of the relaxation activity in V-C8 nuclear extract were almost completely restored by transfection of V-C8 cells with the murine Brca2 gene or by the transfer of human chromosome 13 providing the BRCA2 gene. These results indicate that the observed changes in the topoisomerase I activity in V-C8 are due to the defective function of the Brca2 gene.
    Źródło:
    Acta Biochimica Polonica; 2003, 50, 1; 139-144
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Results of screening in Lublin Province, Poland, for colorectal cancer and neoplastic polyps - the role of environmental factors
    Autorzy:
    Cichoż-Lach, Halina
    Szumiło, Justyna
    Celiński, Krzysztof
    Kasztelan-Szczerbińska, Beata
    Szczerbiński, Mariusz
    Swatek, Jarosław
    Wronecki, Lech
    Wargocki, Janusz
    Słomka, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/989962.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    neoplastic polyps of colon
    advanced adenoma of colon
    colorectal cancer screening
    Opis:
    Introduction and objective. Screening colonoscopy is a recommended tool, and the most sensitive and cost-effective method for reducing the incidence of colorectal cancer (CRC). Objective. The purpose of the study was to present the results of a 5-year screening for early detection of CRC carried out among the population of the central-eastern regions of Poland, primarily in Lublin Province. Materials and method. Screening colonoscopy was conducted in a group of 1,009 patients – 636 women and 373 men, aged 40–65 years. Results. Neoplastic polyps were found in 275 patients, advanced adenomas in 49 patients and adenocarcinoma in 13. 70.55% of neoplastic polyps was located in the distal colon, 18.9% in the proximal part and 10.55% in both regions, advanced adenomas in 79.59%, 8.16% and 12.25%, respectively. Adenocarcinoma was located in the proximal colon in 2 cases and in the distal region in 11 cases. Neoplastic polyps and advanced adenomas occurred significantly more frequently in smokers than in non-smokers. Neoplastic polyps were found statistically more frequent in males than in females, among the overweight and obese patients, than in subjects with normal BMI, and more frequently in the group of urban, compared to rural patients. However, the frequency of advanced adenomas and CRC was not statistically different in those groups. The incidence of CRC was statistically more frequent in males than in females. Smoking and male gender were significant risk factors for developing neoplastic polyps. Male gender seemed to predispose to CRC. Obesity was found to favour advanced adenomas. Conclusions. The results of screening found neoplastic polyps in every third person (mean) who did not have any symptoms suggestive of colon pathology. Advanced adenomas were found in 5% of the examined and CRC was detected in 1.29% of participants. Smoking, male gender and overweight were significant risk factors for developing neoplastic polyps. No correlation was found between gender and the location of neoplastic polyps and advanced adenomas in the colon.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 1
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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