Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę "Szpila, Marcin" wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Wyniki ratowniczych badań przeprowadzonych na wielokulturowym stanowisku w Łowcach, stan. 17, gm. Chłopice, pow. jarosławski
Results of rescue excavations carried out at the multicultural site in Łowce, site 17, Chłopice commune, Jarosław district
Autorzy:
Głowacz, Michał
Szpila, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/567539.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Instytut Archeologii Uniwersytetu Rzeszowskiego. Muzeum Okręgowe w Rzeszowie
Tematy:
settlement
late Bronze Age
early Iron Age
Funnel Beaker culture
Mierzanowice culture
Tarnobrzeg Lusatian culture
Opis:
The article presents the results of rescue excavations carried out in August 2018, at the archaeological site Łowce 17. The site is located on the extreme promontory of the loess lobe, extending at an altitude of 210m above sea level, near the riverbed of the Łęg Rokietnicki River. The value of this place has been confirmed several times by surface surveys, which provided the evidence of artefacts from the Neolithic period, Bronze Age, Roman influence and Early Middle Ages. In the course of excavations, an area of one are was examined. After removing the surface layer, an accumulation layer was recorded at the level of 40 cm, with numerous Neolithic and Bronze Age materials, together with an iron artefact. Below, at a level of about 50 cm, a layer of yellow loess was uncovered, in which features of the Mierzanowice culture, the Tarnobrzeg Łużycka culture and features of unknown chronology were recorded. In total, 20 features of an economic nature were registered, containing ceramic, flint and stone artefacts in their fills, as well as burnt daub and animal bones were noted. Moreover, secondary deposited material was observed in some features. In the next stage of research, the obtained materials were analyzed, which were mainly represented by pottery vessels. The research included the analysis in terms of technology, morphology and ornamentation, based on macroscopic characteristics. As a result of these observations, an attempt was made to determine the relative chronology, distinguishing the ceramics of the Funnel Beaker culture, the Globular Amphora culture, the Mierzanowice culture, the Trzciniec culture and the Tarnobrzeg Lusatian culture. The assessment of the cultural affiliation of flint materials was difficult due to the uncharacteristic forms or lack of context. With reference to artefacts coming from the accumulation layer, a miniature axe/chisel made of Volyn flint was found, which can be attributed to the activities of the TRB and an iron axe/adze with undetermined chronology. As a result of the research, it was possible to confirm the high importance of site No. 17 in Łowce, which was a settlement enclave from the Middle Neolithic period to the Early Middle Ages. The studied area was part of the settlement of the Mierzanowice culture and Tarnobrzeg Lusatian culture. Certainly the following years of research will provide a lot of valuable information about the settlement of these communities and the importance of the region.
Źródło:
Materiały i Sprawozdania Rzeszowskiego Ośrodka Archeologicznego; 2019, 40; 255-278
0137-5725
Pojawia się w:
Materiały i Sprawozdania Rzeszowskiego Ośrodka Archeologicznego
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cu,Zn-superoxide dismutase deficiency in mice leads to organ-specific increase in oxidatively damaged DNA and NF-κB1 protein activity
Autorzy:
Siomek, Agnieszka
Brzoska, Kamil
Sochanowicz, Barbara
Gackowski, Daniel
Rozalski, Rafal
Foksinski, Marek
Zarakowska, Ewelina
Szpila, Anna
Guz, Jolanta
Bartlomiejczyk, Teresa
Kalinowski, Bartlomiej
Kruszewski, Marcin
Olinski, Ryszard
Powiązania:
https://bibliotekanauki.pl/articles/1042730.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Cu,Zn-SOD deficiency
NF-κB pathway
oxidative stress
Opis:
Earlier experimental studies have demonstrated that: i) Cu,Zn-superoxide dismutase deficiency leads to oxidative stress and carcinogenesis; ii) dysregulation of NF-κB pathway can mediate a wide variety of diseases, including cancer. Therefore, we decided, for the first time, to examine the level of oxidative DNA damage and the DNA binding activity of NF-κB proteins in SOD1 knockout, heterozygous and wild-type mice. Two kinds of biomarkers of oxidatively damaged DNA: urinary excretion of 8-oxodG and 8-oxoGua, and the level of oxidatively damaged DNA were analysed using HPLC-GC-MS and HPLC-EC. The DNA binding activity of p50 and p65 proteins in a nuclear extracts was assessed using NF-κB p50/p65 EZ-TFA transcription factor assay. These parameters were determined in the brain, liver, kidney and urine of SOD1 knockout, heterozygous and wild-type mice. The level of 8-oxodG in DNA was higher in the liver and kidney of knockout mice than in wild type. No differences were found in urinary excretion of 8-oxoGua and 8-oxodG between wild type and the SOD1-deficient animals. The activity of the p50 protein was higher in the kidneys, but surprisingly not in the livers of SOD1-deficient mice, whereas p65 activity did not show any variability. Our results indicate that in Cu,Zn-SOD-deficient animals the level of oxidative DNA damage and NF-κB1 activity are elevated in certain organs only, which may provide some explanation for organ-specific ROS-induced carcinogenesis.
Źródło:
Acta Biochimica Polonica; 2010, 57, 4; 577-583
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies