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Wyszukujesz frazę "Stachowiak, Zuzanna" wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Early response of selected haemostatic and haematological parameters to physical activity in young women - the potential impact of oral contraceptives
Autorzy:
Jastrzębska, Maria
Żyżniewska-Banaszak, Ewelina
Nawrot, Małgorzata
Marcinowska, Zuzanna
Siennicka, Aldona
Chełstowski, Kornel
Stachowiak, Paweł
Kordaczuk, Michał
Przybycień, Krzysztof
Clark, Jeremy
Powiązania:
https://bibliotekanauki.pl/articles/972632.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
exercise
contraception
haemostasis
platelet function tests
cell derived microparticles
Opis:
Introduction and objective. Exercise (submaximal) in untrained subjects can modify haemostasis toward hypercoagulability, especially among women using oral contraceptives (OC). The aim of this study was to investigate whether this can be explained by platelet haemostasis and changes in the generation of membrane microparticles. Materials and method. Young, healthy women (n=60) were divided into 2 equal groups: a study group OC (+) who had used OC for >3 months, and controls who had never used oral contraceptives OC(-). Exclusion criteria: those with systematic daily physical activity. Participants were subjected to treadmill exercise (Cardiac Diagnostic System; model CH2000) using the Bruce protocol/ AHA guidelines. Platelet aggregation with arachidonic acid (ASPI test) or ADP (ADP test), membrane microparticle (MP) activity, plasma coagulation times (APTT/PT) and blood count were determined before and 45 minutes after exercise. Results. Before exercise, the OC(+) group had slightly higher platelet aggregation (ADP test), significantly lower MP activity, slightly lower PLT and slightly higher PDW rate. Exercise caused slight inhibition of platelet aggregation (ASPI test), and significant decrease in MP activity – only in the OC(-) group. After exercise, in both groups there was a significant decrease in PLT and increase in WBC, more pronounced in OC(+) group. Conclusions. Submaximal exercise was beneficial for haemostasis in women not using hormonal contraception, associated primarily with reduced MP activity. No beneficial effects of physical activity were found for women using hormonal contraceptives, possibly associated with a hypercoagulable state, and higher reactivity of blood platelets under the influence of the use of contraceptives.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Access to vaccination in the Greater Poland (Poland)
Autorzy:
Zaprutko, Tomasz
Kopciuch, Dorota
Paczkowska, Anna
Sawicka, Dominika
Stachowiak, Zuzanna
Bogdaniec, Patrycja
Kus, Krzysztof
Nowakowska, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/895651.pdf
Data publikacji:
2019-02-28
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
poland
vaccines
access
pharmaceutical market
pharmacies
Opis:
Immunization is a very effective health intervention. Moreover, the global vaccines market has been growing rapidly and costs of full children immunization are dramatically higher nowadays than 30 years ago. High vaccine prices may limit affordability of vaccination which is why we attempted an evaluation of availability and affordability of 7 and non-reimbursed vaccines mostly used in children in Poland. The study was conducted between October 2016 and October 2017 using a specially designed anonymous questionnaire comprising three closed-ended questions. The study tool was distributed by direct contact or via the Internet. Eventually, answers from 505 pharmacies from the Greater Poland region and 10 primary care clinics were included. 5 out of 7 vaccines were available in all types of facilities. There were some issues, however, with availability of Bexsero® and Nimenrix®. Considering prices, the highest difference (of more than 100%) was found for Infanrix hexa® and the lowest (38.5%), for Infanrix IPV+HIB®. In 88.17% of pharmacies included, patients were informed about a thermo-insulating package. 48.39% of respondents indicated that such package is free of charge, while in other pharmacies an average price for the package was EUR 0.48. Although availability and affordability of medicines are crucial objectives of the public health policy, it seems that access to vaccines in Poland might be an area for improvement. Thus, prices of non-reimbursed vaccines could be regulated in Poland nationwide. Moreover, to provide trustworthy information concerning vaccination, healthcare decision makers should consider social education about immunization as an important issue.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 1; 195-201
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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