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    Wyświetlanie 1-5 z 5
    Tytuł:
    Józef Ignacy Kraszewski jako historyk : naukowy fundament wykładu dziejów Litwy w monografii Wilna
    Autorzy:
    Sołtys, Karolina.
    Współwytwórcy:
    Polska Akademia Nauk. Instytut Historii Nauki im. Ludwika i Aleksandra Birkenmajerów. pbl
    Oficyna Wydawnicza Aspra-JR. pbl
    Data publikacji:
    2013
    Wydawca:
    Warszawa : Instytut Historii Nauki Polskiej Akademii Nauk : Oficyna Wydawnicza Aspra-JR
    Tematy:
    Kraszewski, Józef Ignacy (1812-1887). Wilno od początków jego do roku 1750
    Historiografia polska
    Opis:
    Bibliogr. s. 229-[239].
    Dostawca treści:
    Bibliografia CBW
    Książka
    Tytuł:
    Perceived social support, spiritual well-being, and daily life fatigue in family caregivers of home mechanically ventilated individuals
    Autorzy:
    Szatkowska, Karolina
    Sołtys, Michalina
    Powiązania:
    https://bibliotekanauki.pl/articles/2127271.pdf
    Data publikacji:
    2019-04-08
    Wydawca:
    Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
    Tematy:
    perceived social support
    spiritual well-being
    daily life fatigue
    family caregivers
    home mechanical ventilation
    Opis:
    Providing care to a chronically ill person is a stressful situation, which may lead to burden. However, personal and social resources such as social support and spiritual well-being can protect caregivers from these negative consequences. To assess the role of these resources in counteracting fatigue, we examined 55 caregivers of their home mechanically ventilated relatives. The variables were measured with the Perceived Social Support Questionnaire, the Daily Life Fatigue Questionnaire, the Spiritual Index of Well-Being, and a survey. The method of ventilation did not differentiate resources and daily life fatigue in caregivers. Perceived social support was not significantly correlated with fatigue, but spiritual well-being correlated negatively with physical, mental, and social fatigue. Spiritual well-being can partly protect from daily life fatigue in the physical and mental areas.
    Źródło:
    Roczniki Psychologiczne; 2018, 21, 1; 53-68
    1507-7888
    Pojawia się w:
    Roczniki Psychologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Białka uczestniczące w transporcie jonów żelaza(II) w bakteriach gram-ujemnych
    Proteins involved in the ferrous ions transport in gram-negative bacteria
    Autorzy:
    Kierpiec, Karolina
    Stokowa-Sołtys, Kamila
    Powiązania:
    https://bibliotekanauki.pl/articles/1413209.pdf
    Data publikacji:
    2021
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    transport jonów żelaza(II)
    bakterie gram-ujemne
    Feo
    ferrous iron transport
    Hmu
    hemin uptake protein
    ferrous ions transport
    gram-negative bacteria
    Opis:
    Continuous increase in the number of multidrug-resistant strains forces us to look for drugs with completely new mode of action. One of the bacterial property determining the pathogenicity of these microorganisms is their ability to obtain iron. Because in the living environment of these single-celled individuals, its concentration is much lower than this necessary for their growth. For this reason, bacteria created various type of iron aquisition systems, including the Feo system, which mechanism of Fe2+ ion uptake is not fully understood, and protein from the Hmu family belonging to ABC transporters. The Feo transport system is one of the most common systems that is exclusively responsible for importing Fe2+ ions. It consists of three proteins: FeoA, FeoB and FeoC. FeoB is a transmembrane protein that is believed to play a key role in the mechanism of Fe2+ ion uptake. The other two components are cytoplasmic proteins. Both, FeoA and FeoC, are cytoplasmic proteins resembling the construction of transcription regulators. ABC transporters play an equally important role in maintaining iron homeostasis. These include proteins from Hmu family. HmuUV complex catalyses the import of these ions in hem iron form. The structure of this complex consists of TMD dimer (HmuU) and NBD dimer (HmuV). The HmuU is considered to be a permease - just like the FeoB described earlier while HmuV is the ATP binding protein.
    Źródło:
    Wiadomości Chemiczne; 2021, 75, 3-4; 375-394
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Autotoksyczność roślin jako przykład oddziaływań allelopatycznych
    Plant autotoxicity - an example of allelopathic interaction
    Autorzy:
    Sołtys, Dorota
    Dębska, Karolina
    Bogatek, Renata
    Gniazdowska, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/1195907.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Przyrodników im. Kopernika
    Opis:
    Autotoxicity is a type of intraspecific allelopathy (autoallelopathy), caused through the release into the environment compounds, which belong to secondary metabolites. Autotoxicity is observed in natural environment and in agroecosystems. It causes both, beneficial and negative effects. Autoallelopathy allows plants to survive by avoiding intra-competition. On the other hand, it is a serious economical problem. Accumulation of autotoxins in the soil causes soil sickness, and results in negative effects on plant photosynthesis, respiration, hormonal balance or ion uptake and finally led to increase in yield losses. Some species developed mechanisms to avoid autotoxicity by sequestration of the toxic compounds in cell compartments or by binding them in form of glycosides. The phenomenon of autotoxicity could be exploited also as weed management strategy.
    Źródło:
    Kosmos; 2010, 59, 3-4; 551-566
    0023-4249
    Pojawia się w:
    Kosmos
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bakteryjne strategie wykorzystania jonów metali – kulisy chemii koordynacyjnej
    Bacterial strategies for the use of metal ions – backstage of coordiantion chemistry
    Autorzy:
    Piasta, Karolina
    Mular, Andrzej
    Rola, Anna
    Dzyhovskyi, Valentyn
    Potok, Paulina
    Orzeł, Bartosz
    Potocki, Sławomir
    Stokowa-Sołtys, Kamila
    Kozłowski, Henryk
    Gumienna-Kontecka, Elżbieta
    Powiązania:
    https://bibliotekanauki.pl/articles/2200580.pdf
    Data publikacji:
    2022
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    homeostaza metali
    metalofory
    metaloproteiny
    toksyczność metali
    metal homeostasis
    metalophores
    metalloproteins
    metal toxicit
    Opis:
    In the Biological Inorganic Chemistry Group we are inspired to better understand metal ions acquisition and homeostasis in pathogenic bacteria, and in this review we present three different approaches to the role of these processes. The growing importance of a full understanding of the iron transport system in pathogens prompted us to study synthetic analogs of siderophores, used as structural probes in the process of iron uptake by microorganisms. The ferrichrome biomimetic analogs allowed efficient Fe(III) chelation under biological conditions and were recognized better by P. putida. than E. coli, suggesting differences in uptake mechanisms. Addition of a fluorescent probe to the compound allowed to track biological fate of studied complexes [1, 2]. Biomimetics of ferrioxamine E revealed their potential as radioactive 68Ga(III)-based probes [3], and studies of Zr(IV) complexes permitted to explain the in vivo behavior of desferrioxamine B as 89Zr(IV) radionuclide carrier [4], as well as design better chelators for this metal ion [5]. One of the possible mammalian immune system responsesto mycobacterial infection is the increase of Zn(II) concentration in phagosomes to a toxic level [6-8]. The mycobacterial SmtB protein is a transcription regulator that in the presence of high concentrations of metals, dissociates from DNA and activates the expression of metal efflux proteins. We focused on α5 Zn(II) binding domains of SmtB/BigR4 proteins [9], looking at the coordination modes and thermodynamics of their Zn(II) and Ni(II) complexes. The study points out the specificity of metal-ligand interactions and the effect of mutations on the coordination properties of studied systems. The project can be considered as an introduction to the new strategies in tuberculosis treatment based on Zn(II)/Ni(II)-sensitive mechanisms. F. nucleatum is an anaerobic bacteria present in the plaque. It leads not only to periodontal diseases but also, angina, purulent inflammation of the lung tissue or reproductive organs [10]. Moreover, F. nucleatum promotes colon cancer growth [11]. This bacteria strain promotes inflammation and tumorigenesis by modulating the tumor immune microenvironment [12, 13]. Microbial pathogens drive tumorigenesis in 15–20% of cancer cases [14]. However, not only microorganisms are considered a major risk factor, but also metal ions play an important role in tumor promotion [15, 16]. Therefore, our primary research goal is to investigate the effect of metal ions coordination on the activity of outer-membrane proteins from F. nucleatum and to answer whether these proteins increase the prooxidative activity of Cu(II) and Fe(II) ions [16-18].
    Źródło:
    Wiadomości Chemiczne; 2022, 76, 5-6; 287-308
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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