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    Wyświetlanie 1-23 z 23
    Tytuł:
    Commercial metal-based nanocolloids - lack of virucidal activity against ECBO virus
    Autorzy:
    Malaczewska, J.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/31630.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Metallic nanoparticles, mainly silver ones, have been widely used as antibacterial agents, and some studies shown they also exert direct antiviral activity against both enveloped and non-enveloped viruses. The objective of this study has been to evaluate the virucidal activity of commercial silver, gold, copper and platinum nanocolloids, recommended by the manufacturer as antimicrobials, against the ECBO virus, according to Polish Standard PN-EN 14675:2006. The highest experimentally observed decrease in the viral load was 0.875 log, which - when contrasted with the reduction in virus titre of at least 4 log expected from disinfectants - indicates that none of the analyzed nanocolloids had a disinfectant power towards the ECBO virus under the conditions defined by the standard.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The in vitro effect of commercially available noble metal nanocolloids on the rainbow trout (Oncorhynchus mykiss) leukocyte and splenocyte activity
    Autorzy:
    Malaczewska, J.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/31961.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The growing popularity of nanotechnology in the past decade has increased nanomaterial concentrations in the environment and the risk of their toxicity for aquatic organisms. Metal nanoparticles, which are easily absorbed and accumulated by fish, are probably able to interact directly with their immunocompetent cells. The objective of this study was to evaluate the in vitro effect of commercially available silver, gold and copper nanocolloids on the rainbow trout leukocyte and splenocyte activity. At high concentrations, all of the nanocolloids studied had adverse effects on the proliferative response of trout lymphocytes, and the most toxic of them, silver, decreased also the respiratory burst activity of splenocytes. Low concentrations of silver nanocolloid, however, had a stimulating effect on the lymhocyte proliferation.
    Źródło:
    Polish Journal of Veterinary Sciences; 2013, 16, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Retroviruses of wild and cultured fish
    Autorzy:
    Lepa, A.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/31086.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Retroviruses comprise a large group of enveloped RNA viruses which have been found in a wide range of vertebrate species including fish. To date a number of fish retrovirus genomes have been partially or completely sequenced. Phylogenetic analysis and genome organization indicate a high diversity of fish retroviruses as well as some unique structural features that have not been found in any other retroviruses. Piscine retroviruses comprise both exogenous and endogenous viruses; most of them are associated with proliferative diseases. Because several of these proliferative diseases have a seasonal trend, they provide an excellent model for studying tumor development and regression. The aim of this work was to review the best-described fish retroviruses.
    Źródło:
    Polish Journal of Veterinary Sciences; 2011, 14, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of DNA vaccines in fish
    Autorzy:
    Lepa, A
    Siwicki, A.K.
    Terech-Majewska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/31293.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    fish
    DNA vaccine
    infectious disease
    disease control
    vaccination
    immune response
    pathogen
    animal pathogen
    Opis:
    Vaccination is a most cost-effective way of controlling infectious diseases in fish. However, some vaccination techniques when applied to hatchery conditions are not as effective as we expect them to be. Modern molecular biology techniques offer a number of opportunities for improving existing bacterial or viral vaccines or creating new ones. One of the most promising trends in vaccinology is development of DNA vaccination. DNA vaccines are based on the gene encoding specific antigen, which is expressed in vaccinated organism and induces the host immune system. DNA vaccines, compared to conventional vaccines, have many advantages including ability to trigger wider immune response, bigger stability and possibility of large-scale production. To date, there are several reports indicating effectiveness of DNA vaccines used against fish pathogens.
    Źródło:
    Polish Journal of Veterinary Sciences; 2010, 13, 1; 213-215
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Water as a source of macronutrients and micronutrients for fish with special emphasis on the nutritional requirements of two fish species: the common carp (Cyprinus carpio) and the rainbow trout (Oncorhynchus mykiss)
    Autorzy:
    Terech-Majewska, E.
    Pajdak, J.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/962728.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Opis:
    In contrast to terrestrial animals, fish can ingest minerals from food or directly from water. Although micro- and macro-elements are needed in small quantities, they play a key role in many metabolic processes. Trace mineral and macromineral deficiencies may go unnoticed due to an absence of clear clinical symptoms in fish. Absorption processes are determined by various factors, mostly mineral concentrations in water but also other water parameters. The required dietary supplementation of macronutrients and micronutrients is very difficult to determine, and the amount of nutrients absorbed by fish from water is equally difficult to measure. Interactions between elements should also be taken into consideration. Many authors emphasize that phosphates may reduce the absorption of most micronutrients. Also, the current parameters of the water can affect the bioavailability. Some elements such as calcium, chlorine and sodium can be absorbed from ambient water in a quantity sufficient to meet the demand for this element. Other elements, however, require supplementation in a diet. For example, studies indicate the need for supplementation of phosphorus, zinc, copper and manganese. Most research concentrates on feedstuff as a source of micro- and macronutrients. Meanwhile, information concerning bioavailability of minerals directly from water is scarce. The aim of this study was to analyse literature from a different perspective, and concentrate on water as a source of minerals in fish nutrition. Measurements of water parameters such as temperature, pH, nitrate and nitrite levels and the amount of dissolved oxygen are a regular component of environmental control in fish farming. Determination of micro- and macro-element levels, however, remains uncommon in aquaculture. Measurements of these parameters could suggest which elements need to be supplemented and which are found in water in amounts that satisfy the needs of the fish.
    Źródło:
    Journal of Elementology; 2016, 21, 3
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of investation with Diplostomum spp. on nonspecific immunity response of Siberian sturgeon [Acipenser baeri Brandt]
    Autorzy:
    Kolman, H.
    Kolman, R.
    Dzika, E.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/840779.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    fish
    immunity response
    invasion
    Siberian sturgeon
    Acipenser baeri
    Diplostomum
    larva
    sturgeon
    invasive larva
    Źródło:
    Annals of Parasitology; 1998, 44, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The in vitro effect of bovine lactoferrin on the activity of organ leukocytes in rainbow trout [Oncorhynchus mykiss], European eel [Anguilla anguilla] and wels catfish [Silurus glanis]
    Autorzy:
    Malaczewska, J
    Wojcik, M.
    Wojcik, R.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/30969.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    fish
    rainbow trout
    Oncorhynchus mykiss
    European eel
    Anguilla anguilla
    catfish
    Silurus glanis
    in vitro effect
    bovine lactoferrin
    lactoferrin
    leucocyte
    freshwater fish
    Opis:
    Lactoferrin (LF) is a glycoprotein found in milk, neutrophil granules, secretions and selected organs of mammals. Lactoferrin exhibits antibacterial, antiviral, fungicidal, immunoregulatory and other functions. Although fish are devoid of this protein and its cell receptors, LF effect on the immune mechanisms of fish has been demonstrated. The objective of this study was to investigate the effect of bovine lactoferrin, applied in vitro, on the activity of head kidney and spleen leukocytes in three freshwater fish species: rainbow trout (Oncorhynchus mykiss), European eel (Anguilla anguilla) and weis catfish (Silurus glanis). The obtained results validate LF beneficial effect on the respiratory burst of phagocytes in rainbow trout and weis catfish despite the fact that the potential killing activity against Aeromonas hydrophila was not stimulated in any of the studied species. Bovine lactoferrin enhanced the proliferation of T-lymphocytes in rainbow trout and European eel, as well as of B-lymphocytes in rainbow trout.
    Źródło:
    Polish Journal of Veterinary Sciences; 2010, 13, 1; 83-88
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effects of prenatal exposure to methylxanthines
    Autorzy:
    Skopinski, P.
    Woronkowicz, M.
    Skopinska-Rozewska, E.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/31027.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    This review discusses epidemiology and laboratory studies on the effects of prenatal methylxanthine administration on some systems developing organisms. They are mainly absorbed from coffee, tea and cocoa products such as cola beverages and chocolate bars. Prenatal methylxanthine exposure can induce several unfavourables changes in the developing organism, which are persistent even in later phases of life. Based on results obtained from animal studies, the effect on embryogenesis is not only poorly understood but also controversial. It is therefore important to study interspecies differences as results may differ depending on animals used and administration methods.
    Źródło:
    Polish Journal of Veterinary Sciences; 2011, 14, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Biological effects of conjugated linoleic acids supplementation
    Autorzy:
    Oleszczuk, J.
    Oleszczuk, L.
    Siwicki, A.K.
    Skopinska-Rozewska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/32126.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Conjugated linoleic acids (CLA) are a group of polyunsaturated fatty acids (PUFA) with a single pair of conjugated double bonds. The major natural CLA isomer is 18:2 cis-9, trans-11 (c9, t11) linoleic acid, or rumenic acid (RA). Chemically synthesized CLA is also available, mostly as a mixture of RA and 18:2 trans-10, cis-12 (t10, c12) isomers in equal amounts (50:50). Consumption of ruminant meat (beef and lamb) and dairy products (milk and cheese) is the main source of dietary exposure to CLA. Despite numerous studies on animal and human models (tumorigenesis, obesity, immune response) it has not been established whether additional supplementation of CLA is of benefit. Moreover, some studies, conducted both in animals and in humans, reveal that CLA isomers may induce insulin resistance. Presently, balanced diet rich in CLA from natural sources is recommended. The purpose of this review was to sum up the results available in the literature.
    Źródło:
    Polish Journal of Veterinary Sciences; 2012, 15, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Immunosuppressive influence of Anguillid herpesvirus-1 (AngHV-1) infection on cellular defense mechanisms in European eel (Anguilla anguilla)
    Autorzy:
    Schulz, P.
    Deperasińska, I.
    Kaczorek-Łukowska, E.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087405.pdf
    Data publikacji:
    2019
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    alloherpesviruses
    cellular immunity
    immunosuppression
    innate immunity
    Źródło:
    Polish Journal of Veterinary Sciences; 2019, 4; 785-787
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of beta-hydroxy-beta-methylbutyrate (HMB) on the proliferative response of blood lymphocytes and the phagocytic activity of blood monocytes and granulocytes in calves
    Autorzy:
    Wojcik, R.
    Malaczewska, J.
    Siwicki, A.K.
    Micinski, J.
    Zwierzchowski, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/32319.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The objective of this study was to evaluate the effect of HMB on selected indicators of immunity in calves. The experiment was performed on 14 calves aged 30±2 days, divided into two equal groups of control (group I) and experimental (group II) animals. The feed administered to experimental group calves was supplemented with HMB at 40 mg/kg BW, whereas control calves were administered standard farm-made feed without supplementation. Blood was sampled from the jugular vein immediately before the experiment (day 0) and on experimental days 15, 30 and 60 to determine the following parameters of immunity: proliferative response of LPS- and ConA-stimulated lymphocytes (MTT), respiratory burst activity (RBA) and potential killing activity (PKA) of phagocytes. The results revealed a significant increase in RBA and MTT values in calves administered HMB in comparison with the control group throughout the experiment. In the group of animals receiving HMB, an increase in PKA values was noted only on day 30.
    Źródło:
    Polish Journal of Veterinary Sciences; 2013, 16, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of beta-hydroxy-beta-methylbutyrate (HMB) on selected parameters of humoral immunity in calves
    Autorzy:
    Wojcik, R.
    Malaczewska, J.
    Siwicki, A.K.
    Micinski, J.
    Zwierzchowski, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087958.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The objective of this study was to evaluate the effect of HMB on selected parameters of the humoral immunity in calves. The experiment was performed on 14 calves aged 30 ± 2 days, divided into two equal groups of control (group K) and experimental (group H) animals. The feed administered to the experimental calves was supplemented with HMB at 40 mg/kg BW, whereas the control calves were administered standard farm-made feed without supplementation. Blood was sampled from the jugular vein immediately before the experiment (day 0) and on experimental days 15, 30 and 60 to determine the following immunological parameters: total protein levels, gammaglobulin levels, lysozyme activity and ceruloplasmin activity. An analysis of the results obtained revealed a significant increase (p < 0.05; p < 0.01; p < 0.001 respectively) in gammaglobulin levels and lysozyme activity throughout the entire experimental period, an increase (p < 0.05; p < 0.01 respectively) in ceruloplasmin activity on experimental days 15 and 30, but no changes in serum total protein levels of calves administered HMB as compared to those found in the control group.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 2; 357-359
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of LPS injections on non-specific immune response in affected pigeons
    Autorzy:
    Dudek, K.
    Bednarek, D
    Siwicki, A K
    Rokita, E
    Studzinski, T
    Powiązania:
    https://bibliotekanauki.pl/articles/30177.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The aim of the study was to investigate the effect of LPS injections on non-specific mechanisms of immunity in pigeons. On the first day of observation the experimental birds (n=18) were intravenously injected with Escherichia coli LPS (10 μg/kg b.w.), while the control animals (n=6) received in the same way apyrogenic physiological saline. On the second and the third day of the experiment LPS in the same doses was injected again. Four and a half hours after the saline and each pyrogen administration blood samples were collected from the control and experimental pigeons. The total protein, gamma globulin, lysozyme, acute phase protein (Cp, CRP, Tf, ferritin, Alb) and selected trace element (Fe, Cu, Zn) concentrations were investigated. The obtained results showed the increase in the concentration of total protein, Cp, CRP and Tf in endotoxin fever resulting from LPS injection in pigeons. In contrast, the concentration of gamma globulins, ferritin and Alb were decreased in response to the first LPS injection. However, the consecutive injections of LPS caused a decrease in the concentration of total protein, CRP and Tf. In opposition to those results, a significant rise in the lysozyme and ferritin concentrations was observed. On the other hand, the first LPS injection caused a decline in the iron and zinc concentrations which remaining lower than the control values following repeated administration of LPS. On the contrary, the copper concentration increased successively in response to the next LPS injections.
    Źródło:
    Polish Journal of Veterinary Sciences; 2013, 16, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The in vitro effect of kynurenic acid on the rainbow trout (Oncorhynchus mykiss) leukocyte and splenocyte activity
    Autorzy:
    Malaczewska, J.
    Siwicki, A.K.
    Wojcik, R.
    Turski, W.A.
    Kaczorek, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/32542.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Kynurenic acid (KYNA), an endogenous neuroprotectant formed along the kynurenine pathway of tryptophan degradation, is a selective ligand of the GPR35 receptor, which can be found on the surface of various populations of human immune cells. In infections and inflammations, KYNA produces an anti-inflammatory effect through this receptor, by depressing the synthesis of reactive oxygen species and pro-inflammatory cytokines. However, it is still unrecognized whether receptors for kynurenic acid are also localized on immune cells of poikilothermic animals, or whether KYNA is able to affect these cells. The objective of this study has been to determine the effect of different concentrations of kynurenic acid (12.5 μM to 10 mM) on the viability and mitogenic response of lymphocytes and on the activity of phagocytic cells isolated from blood and the spleen of rainbow trout. The results imply low toxicity of kynurenic acid towards fish immune cells, and the proliferative effect observed at the two lowest concentrations of KYNA (12.5 μM and 25 μM) seems indicative of endogenous kynurenic acid being capable of activating fish lymphocytes. Non-toxic, micromole concentrations of KYNA, however, had no influence on the mitogenic response of lymphocytes nor on the activity of phagocytes in rainbow trout under in vitro conditions. There is some likelihood that such an effect could be observed at lower, nanomole concentrations of KYNA.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 3
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    In vivo stimulatory effect of multi-component herbal remedy PADMA 28 on mitogen-induced proliferation of mice splenic lymphocytes and their chemokinetic activity
    Autorzy:
    Skopinski, P.
    Radomska-Lesniewska, D M
    Sokolnicka, I
    Balan, B J
    Siwicki, A K
    Skopinska-Rozewska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/31452.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    PADMA 28, a natural herbal multi-compound remedy originates from traditional Tibetan medicine and possesses a variety of beneficial effects on experimental and clinical models of inflammation and atherosclerosis, as well as angioprotecive, antioxidative and wound – healing properties. The aim of the present study was to evaluate the in vivo influence of this remedy on the in vitro mitogen-induced proliferation of murine splenic lymphocytes and their chemokinetic activity in cell culture.The study was performed on 6-8 weeks old inbred Balb/c mice. PADMA28 was administered to mice per os in daily doses 5.8 mg (calculated from the highest dose recommended for human) or 0.085 mg (dose from the range of active doses of other herbal extracts containing polyphenolic substances used previously by us in experiments with mice), for 7 days. Control groups received water. Results: No substantial differences were observed between groups of mice fed with low and high PADMA doses. In both of them, response of splenic lymphocztes to mitogen PHA (p < 0.001) and their in vitro chemokinetic activity (p < 0.001 for low dose and p < 0.01 for high dose) were highly significantly increased as compared to the controls. Conclusion: The results of our investigations suggest that PADMA 28 can stimulate cell-mediated immunity in mice and might be used for this purpose in the wide spectrum of doses.
    Źródło:
    Polish Journal of Veterinary Sciences; 2013, 16, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    In vivo inhibitory effect of Aloe vera gel on the ability of mouse parental splenic lymphocytes to induce cutaneous angiogenesis in recipient F1 mice
    Autorzy:
    Skopinski, P.
    Lewicki, S.
    Balan, B.J.
    Kocik, J.
    Zdanowski, R.
    Skopinska-Rozewska, E.
    Siwicki, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/30546.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Lymphocyte-induced angiogenesis test (LIA) is a model of local graft-versus-host (GVH) reaction, marker of the earliest events resulting from activation of donor lymphocytes after contact with host semi-allogeneic histocompatibility antigens. The effect of in vivo oral administration of Aloe vera gel for 21 days to maternal strain (Balb/c) donor mice on the ability of their splenic lymphocytes to induce cutaneous angiogenesis (LIA test) in F1 Balb/c x C3H recipients, was studied. Results: Neovascular reaction evaluated 72 hours after cells grafting was significantly lower in F1 mice grafted with lymphocytes collected from Aloe- fed donors, than in recipients of lymphocytes collected from respective controls. Conclusions: This observation opens the promise of safe and ethically acceptable possibility of use of Aloe vera gel in human donors in prevention of GVHD in recipients of bone marrow grafts.
    Źródło:
    Polish Journal of Veterinary Sciences; 2014, 17, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Morphometric abnormalities in spleen and kidney of the progeny of mice fed American cranberry extract (Vaccinium macrocarpon) during pregnancy and lactation
    Autorzy:
    Balan, B.J.
    Lewicki, S.
    Siwicki, A.K.
    Stelmasiak, M.
    Skopinski, P.
    Skopinska-Rozewska, E.
    Wasiutynski, A.
    Zdanowski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/30729.pdf
    Data publikacji:
    2017
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Cranberries and cranberry-derived diet supplements are often recommended for the treatment of urinary tract infections, also during pregnancy. These products contain strongly anti-angiogenic chemical compounds which could not be indifferent to the developing fetus. In the present work we evaluated the effect of feeding pregnant and lactating mice American cranberry extract (daily dose 0.88 mg) on the morphology and some parameters of spleen and kidney function of their adult progeny. Six weeks after delivery the morphometry of spleen and kidney, cytometric analysis of spleen lymphocytes, evaluation of humoral response to SRBC (Sheep Red Blood Cells), and examination of serum creatinine/urea concentration, were performed in the offspring. Spleens of progeny from experimental (E) group differed from the spleens of progeny of control mice in the lower number of lymphatic nodules and their larger diameter. Cytometry of spleen cells from progeny of E mothers revealed more CD19⁺ and CD8⁺ lymphocytes than in the control group. No difference was seen in the response to immunization by red blood cells of sheep (SRBC) between control and E offspring. An increase in the diameter of glomeruli was observed in the kidneys of the experimental group in comparison with the control group. No abnormalities in creatinine and urea serum level were observed. A higher concentration of VEGF and bFGF in E offspring sera in comparison to the controls was seen. Conclusion: Although the observed differences between the control and experimental group were not large, caution is recommended in using cranberries and their extracts during pregnancy until more research will be done on this topic.
    Źródło:
    Polish Journal of Veterinary Sciences; 2017, 20, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Spleen content of selected polyphenols, splenocytes morphology and function in mice fed Rhodiola kirilowii extracts during pregnancy and lactation
    Autorzy:
    Lewicki, S.
    Stankiewicz, W.
    Skopinska-Rozewska, E.
    Wilczak, J.
    Lesniak, M.
    Suska, M.
    Siwicki, A.K.
    Skopinski, P.
    Zdanowski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/31572.pdf
    Data publikacji:
    2015
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The genus Rhodiola (Crassulaceae) consists of many species, growing mainly in Asia and traditionally used as adaptogens and anti-inflammatory drugs. In order to elaborate herbal immunostimulator which could be safely given to pregnant women, we performed a study on immunotropic effects of feeding pregnant and lactating mice Rhodiola kirilowii extracts. This paper presents the results of the first part of our study – spleen content of selected polyphenols, spleen cellularity, splenocytes phenotype and their response to mitogens. Experiments were performed on adult inbred females of Balb/c strain, mated with adult males. Females, since copulatory plug was noted, up to the 28-th day after delivery were fed daily with 20 mg/kg b.m. water (RKW) or hydro- lcoholic (RKW-A) extracts of Rhodiola kirilowii. Results: 1. Significantly lower proportion of pregnant mice in experimental groups than in the control. 2. Cellularity of spleen and flavonol quercetin spleen concentration were significantly lower in experimental groups in comparison to the controls. 3. Flavanols ( (+)-catechin and epicatechin) levels were significantly higher in the spleens of experimental mice than in the controls. 4. Positive correlation between spleen cellularity and quercetin, and negative correlation between spleen cellularity and epicatechin content were observed. 5. Spleen mass and spleen lymphocytes phenotype and proliferation in RKW and RKW-A fed mice did not differ from the control. These results, together with suspicion of some embryo- oxicity, are worrying and eliminate the possibility of use Rhodiola kirilowii extracts for long-term treatment in pregnant females.
    Źródło:
    Polish Journal of Veterinary Sciences; 2015, 18, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Suppressive effect of electromagnetic field on analgesic activity of tramadol in rats
    Autorzy:
    Bodera, P.
    Stankiewicz, W.
    Antkowiak, B.
    Paluch, M.
    Kieliszek, J.
    Sobiech, J.
    Zdanowski, R.
    Wojdas, A.
    Siwicki, A.K.
    Skopinska-Rozewska, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/32288.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    suppressive effect
    electromagnetic field
    analgesic activity
    tramadol
    rat
    analgesic effect
    pain perception
    Opis:
    The electromagnetic fields (EMFs) have been shown to alter animal and human behavior, such as directional orientation, learning, pain perception (nociception or analgesia) and anxiety-related behaviors. The aim of this study was to evaluate the influence of electromagnetic fields of high-frequency microwaves on pain perception and anti-nociceptive activity of tramadol (TRAM) - analgetic effective in the treatment of moderate to severe acute and chronic pain states. Electromagnetic fields exposures of a) 1500 MHz frequency and b) modulated, 1800 MHz (which is identical to that generated by mobile phones) were applied. Paw withdrawal latency (PWL) to thermal stimulus was measured in vehicle or tramadol (TRAM) treated animals before and after 30, 60 and 90 minutes from injections. The differences in the level of pain (PWL) between control group and rats exposed to EMF alone in three measurements, were not observed. Tramadol alone significantly increased PWLs to thermal stimulus in comparison to vehicle results at 30 (p < 0.001) and 60 minutes (p < 0.05) after drug injection. EMF exposure of both frequencies transiently suppressed analgesic effect of tramadol, significantly reducing paw withdrawal latency in animals treated with this drug at 30 minutes from the drug injection.
    Źródło:
    Polish Journal of Veterinary Sciences; 2012, 15, 1
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dose-dependent in vivo effect of Rhodiola and Echinacea on the mitogen-induced lymphocyte proliferation in mice
    Autorzy:
    Skopińska-Rozewska, E.
    Sokolnicka, I.
    Siwicki, A.K.
    Stankiewicz, W.
    Dabrowski, M.P.
    Buchwald, W.
    Krajewska-Patan, A.
    Mielcarek, S.
    Mscisz, A.
    Furmanowa, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31333.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    in vivo effect
    Rhodiola rosea
    Echinacea purpurea
    Echinacea angustifolia
    Rhodiola quadrifida
    mitogen-induced lymphocyte
    lymphocyte
    proliferation
    mice
    mouse
    Opis:
    Echinacea purpurea (EP) and Echinacea angustifolia (EA) are ones of the most important world’s herbs with immunotropic activity. They were traditional medicinal plants used by North American Indians for the treatment of various illnesses. Now they are cultivated in many countries and are used mainly to treat respiratory tract infections. Rhodiola rosea (RR) and Rhodiola quadrifida (RQ) are medicinal plants originated from Asia and used traditionally as adaptogens, antidepressants, and anti-inflammatory remedies. We previously reported, that extracts of underground parts of RR and RQ exhibited immunotropic activity. We have demonstrated in pigs that in vitro RR or RQ supplementation of blood lymphocyte cultures stimulated T cell proliferative response to Con A in lower, and inhibited it in higher Rhodiola extract concentrations. The aim of this work was to evaluate the in vivo effect of these herbal remedies on the in vitro proliferative response of mouse splenic lymphocytes to another T-cell mitogen- Phaseolus vulgaris haemagglutinin (PHA). We have found significant stimulation of proliferative response, in comparison to the controls, in mice fed lower doses of tested remedies, and inhibition, no effect or lower stimulation, in mice fed higher doses of these drugs.
    Źródło:
    Polish Journal of Veterinary Sciences; 2011, 14, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of undecanones and their derivatives on tumor angiogenesis and VEGF content
    Autorzy:
    Gibka, J
    Wasiutynski, A.
    Skopinska-Rozewska, E.
    Siwicki, A.K.
    Chorostowska-Wynimko, J.
    Sommer, E.
    Mazurkiewicz, M.
    Glinski, M.
    Skurzak, H.
    Wojcik, R.
    Jung, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/31734.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    mice
    mouse
    undecan-x-one
    derivative
    angiogenesis
    tumour
    VEGF zob.vascular endothelial growth factor
    enantiomer
    histological examination
    vascular endothelial growth factor
    sarcoma cell
    Opis:
    The in vivo effects of some derivatives of aliphatic ketones (2-undecanone, 3-undecanone, 4-undecanone and their derivatives) on L-l sarcoma tumor angiogenesis and VEGF content were studied in Balb/c mice. Mice that inhaled 10% solution of 3-undecanone(3-on) or 1% solution of 2-undecanone propylene acetal (Acpr2) for 3 days after tumor cells implantation, presented lower neovascular response measured by tumor-induced cutaneous angiogenesis test (TIA) and lower tumor VEGF content in 5-days tumors, than non-inhaled controls. Other substances presented various effects on tumor VEGF concentration and angiogenesis. Histological examination of lesions collected from mice inhaled Acpr2, or non-inhaled controls, revealed small diffused areas of necrosis in the former group. In both groups, slight to moderate inflammatory infiltrations were seen at the tumor's margin. In Acpr2 group, there were less small blood vessels at tumor's margin than in the control group.
    Źródło:
    Polish Journal of Veterinary Sciences; 2010, 13, 1; 105-115
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wpływ mannanoligosacharydów na status zdrowotny i jakość mięsa kurcząt brojlerów
    Effect of dietary (mannan)-oligosaccharides on health status and meat quality of broiler chickens
    Autorzy:
    Lipinski, K.
    Tywonczuk, J.
    Siwicki, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/828503.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Technologów Żywności
    Tematy:
    jakosc
    kurczeta brojlery
    mannanooligosacharydy
    mieso drobiowe
    mieszanki paszowe
    prebiotyki
    preparat Biolex-MB40
    status zdrowotny
    zastosowanie
    zywienie zwierzat
    Opis:
    Celem pracy było określenie wpływu zastosowania preparatu prebiotycznego zawierającego mannanoligosacharydy, w mieszankach dla kurcząt brojlerów, na status zdrowotny i jakość mięsa. W mieszankach paszowych w miejsce stymulatora roślinnego i zakwaszacza (grupa kontrolna) zastosowany został preparat prebiotyczny Biolex MB 40 (mannanoligosacharydy) w ilości 2 kg/t mieszanki (grupa II). W grupie doświadczalnej III zastosowano preparat Biolex MB 40 w ilości 2 kg/t i zakwaszacz. W 21 dniu życia od kurcząt pobierano krew i następnie oznaczano w surowicy zawartość białka ogólnego, γ-globulin, lizozymu oraz ceruloplazminy. Po uboju w mięśniu piersiowym oznaczono skład chemiczny mięsa. Zastosowanie w mieszankach dla kurcząt brojlerów preparatu prebiotycznego Biolex MB 40 w ilości 2 kg/t wpływa na poprawę wyników produkcyjnych wyrażonych masą ciała, wykorzystaniem paszy i europejskim wskaźnikiem wydajności. U kurcząt żywionych mieszankami z udziałem badanego preparatu zaobserwowano aktywowanie mechanizmów obrony nieswoistej na zakażenia, czego wyrazem był wzrost poziomu lizozymu w surowicy krwi. Mięso badanych kurcząt charakteryzowało się podobną zawartością suchej masy, popiołu surowego, białka ogólnego i tłuszczu surowego.
    This aim of this study was to determine the effect of the application of a prebiotic preparation containing mannanoligosaccharides, in diets for broiler chickens on health status and meat quality. In the diets for broiler chickens an acidifier and a herbal preparation (control group) were replaced with a prebiotic preparation Biolex MB 40 (mannanoligosaccharides) at 2 kg/t of the diet (group II). In group III, Biolex MB 40 was applied at 2 kg/t and an acidifier. At 21 days of age, blood samples from birds were drawn. The following were determined in the serum: total protein level, γ-globulins, lysozyme and ceruloplasmin. After slaughter chemical analysis of breast muscles was carried out. The application of a prebiotic preparation Biolex MB 40 at 2 kg/t positively affects the production results, expressed as body weight, feed utilization and the European Efficiency Index. The mechanisms of non-specific defence against infections were observed to activate in the chickens fed on the diets with the examined preparation, which was expressed as an increase in lysozyme level in blood serum. The meat of the examined chickens contained similar amounts of dry matter, crude ash, crude protein and crude fat.
    Źródło:
    Żywność Nauka Technologia Jakość; 2009, 16, 4
    1425-6959
    Pojawia się w:
    Żywność Nauka Technologia Jakość
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Infection of European eel, Anguilla anguilla (L.) with the nematode Anguillicoloides crassus (Kuwahara, Niimi et Itagaki,1974) in Polish waters
    Autorzy:
    Popielarczyk, R.
    Robak, S.
    Siwicki, K.A.
    Powiązania:
    https://bibliotekanauki.pl/articles/30470.pdf
    Data publikacji:
    2012
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    The aim of this study was to determine the degree of Anguillicoloides crassus infection in European eel inhabiting Polish waters based on selected parasitic descriptors and on anatomical pathology of the swimbladder using macroscopic methods. In all, 154 European eel specimens were sampled from eleven sites in Poland and A. crassus was present in the swimbladder of 114 fish. The intensity of A. crassus infection in all the eel specimens ranged from 1 to 62 parasites at a mean value of 7.5. High values of mean infection intensity were noted in samples from Pomeranian lakes Bukowo, Łebsko, and Jamno. The health of the swimbladder was evaluated using the swimbladder degenerative index (SDI). The mean value of the SDI for all of the eel examined was 3.3, and extensively degenerated swimbladders were observed mainly in samples in the Szczecin Lagoon and from lakes. According to the individual SDI ratings, 9.1% of the eel specimens did not exhibit pathological symptoms of the swimbladder (SDI-0) and an extremely damaged (SDI-6) swimbladder was noted in 11.7% of the fish examined. In the case of eel infected with A. crassus, higher SDI values were reflected in initially increasing shares in subsequent categories. In fish that were not infected with the nematode, only 20% (8 individuals) of the swimbladders showed no symptoms of pathology (SDI-0).
    Źródło:
    Polish Journal of Veterinary Sciences; 2012, 15, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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