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Wyszukujesz frazę "Sitarek, Piotr" wg kryterium: Autor

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    Wyświetlanie 1-5 z 5
    Tytuł:
    The Impact of EU Law on a National Competition Authoritys Leniency Programme – the Case of Poland
    Autorzy:
    Sitarek, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/530320.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Warszawski. Wydawnictwo Naukowe Wydziału Zarządzania
    Tematy:
    competition law
    leniency, antitrust damages actions
    access to evidence
    procedural autonomy
    efficiency
    public enforcement
    private enforcement
    Opis:
    This paper is devoted to the impact of EU law on national leniency programmes, especially the Polish one. It analyses the jurisprudence of the Court of Justice in Pfleiderer, Donau Chemie and Schenker and identifies three specific areas of potential EU influence on national leniency programmes. The impact of EU law on the rules of access to leniency documents is analysed in detail on the basis of both EU and Polish law and taking into account the Draft Directive on Antitrust Damages Actions. The paper covers also the extent to which the principle of effectiveness of EU law limits the procedural autonomy of Member States in regard to their leniency programmes. This analysis covers both “negative conditions”, that is, elements of national leniency programmes which are incompatible with EU law, and “positive conditions”, in order words, those elements of domestic leniency programmes which are seen as necessary for securing their effectiveness.
    L'article concerne l'influence du droit de l‘Union européenne sur les programmes de clémence nationaux, en particulier le programme polonais. La jurisprudence de la Cour de justice de l’Union européenne est analysée, surtout les arrêts en Pfleiderer, Donau Chemie et Schenker. Les trois avenues de l'influence du droit européen sur le programme de clémence sont identifiés – les règles d'accès aux confessions des entreprises bénéficiaires de la clémence, qui sont analysées en détaille, les limitations des programmes nationaux de clémence à cause du principe d'effectivité et les obligations des autorités nationales de concurrence d’assurer l'effectivité des programmes de clémence
    Źródło:
    Yearbook of Antitrust and Regulatory Studies; 2014, 7(9); 185-216
    1689-9024
    2545-0115
    Pojawia się w:
    Yearbook of Antitrust and Regulatory Studies
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Polish Leniency Programme and its Intersection with Private Enforcement of Competition Law
    Autorzy:
    Rumak, Ewelina
    Sitarek, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/530375.pdf
    Data publikacji:
    2009-12-01
    Wydawca:
    Uniwersytet Warszawski. Wydawnictwo Naukowe Wydziału Zarządzania
    Tematy:
    competition law
    leniency
    whistle-blowing
    cartels
    private enforcement
    discovery
    protection of applications
    follow-on actions
    scope of damages
    Opis:
    This paper is devoted to the Polish leniency programme, including the conditions of obtaining lenient treatment and the applicable procedure. The type, scope and form of information that must be submitted are commented on as well as the marker system and summary applications. The intersection of the leniency scheme with private enforcement of antitrust rules is discussed in detail. Special attention is devoted to the possible ways in which private antitrust plaintiffs might access information submitted to the UOKiK by leniency applicants. Thoroughly analysed are the rules regulating the possibility of obtaining relevant documents from the UOKiK and from the defendant in the course of civil proceedings as well as the status of the administrative decision in subsequent civil litigation. The paper covers also the scope of the leniency recipient’s civil liability and touches upon the possible ways in which it could be limited to enhance the effectiveness of the leniency scheme. Some suggestions de lege ferenda are also provided concerning the means of increasing this effectiveness without prejudice to the private parties’ right to compensation.
    Źródło:
    Yearbook of Antitrust and Regulatory Studies; 2009, 2(2); 99-123
    1689-9024
    2545-0115
    Pojawia się w:
    Yearbook of Antitrust and Regulatory Studies
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Comparative Safety Testing (Acute Systemic Toxicity in Mice) of Two Materials Prepared from Polypropylene-Polyester (Codubix S) or Acrylate Resin (Mendec Cranio) Used for the Manufacturing of a Calvaria Prosthesis
    Porównawcze badanie bezpieczeństwa (ostra toksyczność ogólnoustrojowa u myszy) dwóch materiałów przygotowanych z dzianiny/plecionki polipropylenowo-poliestrowej (Codubix S) oraz żywicy akrylowej (Mendec Cranio) wykorzystywanych do produkcji protez
    Autorzy:
    Sujka, Witold
    Latańska, Ilona
    Stępnik, Maciej
    Sitarek, Krystyna
    Kasprzak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/234064.pdf
    Data publikacji:
    2019
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
    Tematy:
    cranial implant
    cranioplasty
    acute toxicity
    chemical analysis
    polypropylene-polyester
    acrylate resin
    implant czaszki
    plastyka czaszki
    ostra toksyczność
    analiza chemiczna
    polipropylen-poliester
    żywica akrylowa
    Opis:
    The aim of the study was a comparison of the acute toxicity of two popular prostheses used in the reconstruction of the bones of the skull. For the tests, the following materials were used: a polypropylene-polyester knitted Codubix S cranial bone prosthesis, made by TRICOMED SA, and polymethyl methacrylate Mednec Cranio resin. The tests were carried out in accordance with the following standards – PN-EN ISO 10993-11:2009 Biological evaluation of medical devices - Part 11: Tests for systemic toxicity, and PN-EN ISO 10993-12:2012 Biological evaluation of medical devices – Part 12: Sample preparation and reference materials. During the evaluation, adult male and female Balb/c mice were used. The animals were injected intravenously using extracts of both materials in 0.9% NaCl and intraperitoneally with the same extracts in sesame oil. The tests lasted 7 days, during which the health of the animals and their behavior were assessed. Both in the control and test groups, there was no mortality of the animals, and the health and behaviour of mice were unchanged when compared with the normal. After 7 days the internal organs of the chest and abdominal cavity of the animals were subjected to macroscopic pathomorphological examination, during which no changes indicating the toxic action of Codubix S and Mednec Cranio resin were found. Before the acute systemic toxicity tests, the chemical purity of both implants was assessed. The chemical purity of a product is one of the factors determining its biological properties. A product which is characterised by a higher degree of chemical purity contains fewer substances which may have a negative impact on biological reactions. Both prostheses meet the requirements of purity for medical devices.
    Celem badania było porównanie toksyczności ostrej dwóch popularnych protez stosowanych w konstrukcji kości czaszki. Do badań użyto następujących materiałów: dzianiny polipropylenowo-poliestrowej Codubix S firmy TRICOMEX SA. I polimetakrylanu metylu Mednec Cranio. Badania przeprowadzono zgodnie z następującymi normami PN-EN ISO 10993-11: 2009 Biologiczna ocena wyrobów medycznych. Część 11: Badania toksyczności systemowej i PN-EN ISO 10993-12: 2012 Biologiczna ocena wyrobów medycznych Część 12: Przygotowanie próbek i materiały referencyjne. Podczas oceny wykorzystano dorosłe samce i samice myszy Balb /c. Zwierzętom wstrzyknięto: dożylnie stosując ekstrakty obu materiałów w 0,9% NaCl i dootrzewnowo z tymi samymi ekstraktami w oleju sezamowym. Testy trwały 7 dni, podczas których oceniano zdrowie zwierząt i ich zachowanie. Zarówno w grupach kontrolnych, jak i testowych nie stwierdzono śmiertelności zwierząt, zdrowie i zachowanie myszy pozostały nie zmienione w porównaniu ze zwykłymi. Po 7 dniach narządy wewnętrzne klatki piersiowej i jamy brzuszne j zwierząt poddano makroskopowemu badaniu patomorfologicznemu, podczas którego nie stwierdzono zmian wskazujących na toksyczne działanie żywicy Codubix S i Mednec Cranio. Przed badaniami ostrej toksyczności ogólnoustrojowej oceniano czystość chemiczną obu implantów. Chemiczna czystość produktu jest jednym z czynników określających jego właściwości biologiczne. Produkt, który charakteryzuje się wyższym stopniem czystości chemicznej, zawiera mniej substancji, które mogą mieć negatywny wpływ na reakcje biologiczne. Obie protezy spełniają wymagania czystości dla wyrobów medycznych.
    Źródło:
    Fibres & Textiles in Eastern Europe; 2019, 5 (137); 82-88
    1230-3666
    2300-7354
    Pojawia się w:
    Fibres & Textiles in Eastern Europe
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fertility and developmental toxicity studies of diethylene glycol monobutyl ether (DGBE) in rats
    Autorzy:
    Sitarek, Krystyna
    Gromadzińska, Jolanta
    Lutz, Piotr
    Stetkiewicz, Jan
    Świercz, Radosław
    Wąsowicz, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/2180019.pdf
    Data publikacji:
    2012-09-01
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    dimethylene glycol monobutyl ether (DGBE)
    CAS No. 112-34-5
    female and male rats
    fertility
    Opis:
    Objectives The solvent, dimethylene glycol monobutyl ether (DGBE), is a component of latex paints, inks; it is used as a degreasing agent, industrial detergent. The aim of the study was evaluating the effects of DGBE administered by gavage on the estrous cycle and given with drinking water on fertility in rats and early development of their progeny. Materials and Methods Female rats were exposed to DGBE by gavage during 8 weeks at 250, 500 or 1000 mg/kg/day. Vaginal smears were collected during the exposure and 4 weeks after its cessation. Fertility studies were performed in male and female animals exposed to in drinking water. Males were exposed for 10 weeks and then mated with females exposed before mating, during pregnancy and lactation. Young animals were observed during 3 weeks after birth. Results DGBE does not cause disturbances of the menstrual cycle in females. Parameters used to assess the general toxicity indicate that males receiving DGBE in drinking water are more sensitive to this compound than females: significantly greater, dose-dependent relative spleen weight, significant decrease in hematological parameters from 8% to 15% depending on the dose, were observed. Clinical chemistry parameters (HDL-cholesterol, BUN) and some markers of oxidative stress differ between the exposed groups and the control one, but without adverse health effect. The microscopic examination of internal organs did not reveal morphological changes in male and female rats. Conclusion The results of our study on the impact of exposure to DGBE on fertility in rats indicate that the substance administered for 9–10 weeks to females and males at a limit dose of 1000 mg/kg did not impair fertility or viability of their offspring during the first three weeks of life.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2012, 25, 4; 404-417
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Developmental toxicity of N-methylaniline following prenatal oral administration in rats
    Autorzy:
    Sitarek, Krystyna
    Gromadzińska, Jolanta
    Stetkiewicz, Jan
    Lutz, Piotr
    Król, Magdalena
    Domeradzka-Gajda, Katarzyna
    Wąsowicz, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/2177441.pdf
    Data publikacji:
    2016-02-10
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    rat
    N-methylaniline
    NMA
    developmental toxicity
    metHb
    toxicity
    Opis:
    Objectives The objective of the study was to assess prenatal toxicity of N-methylaniline (NMA) administered by gavage to pregnant female rats. Material and Methods Pregnant female rats were administered N-methylaniline in corn oil by gavage at daily doses of 0.8 mg/kg of body weight (b.w.), 4 mg/kg b.w., 20 mg/kg b.w. and 100 mg/kg b.w. from implantation (the 5th day post mating) to the day prior to the scheduled caesarean section (the 20th day of pregnancy). General behavior, body weight, food and water consumption, hematological, biochemical analyses and pathomorphological changes of the dams were recorded. Results All the females survived until the end of the study. The test substance was toxic to pregnant females, even at the lowest of the used doses, i.e., 0.8 mg/kg b.w./day. Lower weight gain during pregnancy and significantly higher NMA-dose-dependent absolute weight of the organs were noted in the exposed females. The females from the groups exposed at doses of 20 mg/kg b.w./day and 100 mg/kg b.w./day developed anemia and showed higher concentrations of free thyroxine (FT3) and free triiodothyronine (FT4) thyroid hormones. Total protein concentration exhibited an increase in all the exposed groups of females. In the prenatal toxicity study, administration of N-methylaniline throughout the embryonic and fetal periods produced embryotoxic effects at doses ranging 4–100 mg/kg b.w./day. Conclusions Considering the data obtained in this study, it is reasonable to assume that N-methylaniline administered orally to pregnant rats is toxic for mothers even at a low dose of 0.8 mg/kg b.w./day. However, this dose was not associated with any significant effects to their offspring. This prenatal exposure level may be considered as no-observed-adverse-effect level (NOAEL) for the progeny and a dose of 4 mg/kg b.w./day as the lowest-observed-adverse-effect level (LOAEL) for the progeny.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2016, 29, 3; 479-492
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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