- Tytuł:
- NF-κB signaling pathway and free radical impact
- Autorzy:
- Siomek, Agnieszka
- Powiązania:
- https://bibliotekanauki.pl/articles/1039704.pdf
- Data publikacji:
- 2012
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
nitrogen oxygen species
NF-κB transcription factors
reactive oxygen species - Opis:
- The activation of NF-κB transcription factor is critical for a wide range of processes such as immunity, inflammation, cell development, growth and survival. It is activated by a variety of stimuli including cytokines, ionizing radiation and oxidative stress. Redox modulations of NF-κB pathway have been widely demonstrated. Studies carried out during last years have advanced our knowledge about possible connections between NF-κB pathway and the impact of free radicals. This review is an endeavor to gather recent results focused on this issue, although an important question, whether oxidative stress plays a physiological role in NF-κB activation, seems to be still unanswered.
- Źródło:
-
Acta Biochimica Polonica; 2012, 59, 3; 323-331
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł