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Wyszukujesz frazę "Singh, Raman Kumar" wg kryterium: Autor

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    Wyświetlanie 1-3 z 3
    Tytuł:
    Synthesis, characterization of isoxazole derivatives and evaluation of their antibacterial, antioxidant and anticancer activity
    Autorzy:
    Vashisht, Ketan
    Sethi, Pooja
    Bansal, Anshul
    Singh, Tejveer
    Kumar, Raman
    Singh Tuli, Hardeep
    Saini, Shallu
    Powiązania:
    https://bibliotekanauki.pl/articles/40570865.pdf
    Data publikacji:
    2024-06-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    antibacterial
    antioxidant activity and anticancer potential
    isoxazole
    pathogenic bacterial
    Opis:
    Introduction and aim. The synthesis of heterocyclic compounds containing oxygen and nitrogen is profoundly intriguing due to their mechanistic implications in both research and development within organic chemistry and drug discovery. The primary aim of this study is to fabricate a range of pharmacologically active drugs containing the isoxazole moiety. Material and methods. The synthesis of new derivatives of isoxazole was achieved through a one-pot condensation reaction of 2-[(Substituted phenyl)hydrazono]malononitrile (1) and 3-[(Substituted phenyl)azo]-2,4-Pentanedione (2) with sodium acetate and hydroxylamine hydrochloride (1:1) in ethanol. All the compounds were screened for their in vitro antibacterial activity, in vitro antioxidant and anticancer activity. The synthesized compounds underwent characterization through FTIR, 1H NMR, and 13C NMR analyses, supported by mass spectral data and elemental analysis. Results. A set of novel isoxazole derivatives was synthesized with a favorable yield. Among compounds 1d, 1e, 2c, 2d, and 2e exhibited notable antioxidant activities. Compounds 1a, 1b, and 1c demonstrated significant anticancer potential against prostate cancer [PC3] cell lines compared to normal HEK cell lines, while 2a displayed the highest inhibitory zone against Escherichia coli. Conclusion. Novel compounds with multifaceted biological activities have been successfully designed, and a synthetic route to create isoxazole derivatives has been devised and verified.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2024, 22, 2; 376-387
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Geometrical and optical analysis of small-sized parabolic trough collector using ray tracing tool SolTrace
    Autorzy:
    Singh, Raman Kumar
    Chandra, Prakash
    Powiązania:
    https://bibliotekanauki.pl/articles/27312206.pdf
    Data publikacji:
    2023
    Wydawca:
    Polska Akademia Nauk. Czasopisma i Monografie PAN
    Tematy:
    parabolic trough collector
    SolTrace
    Monte Carlo ray tracing method
    nonuniform heat flux distribution
    optical analysis
    geometrical analysis
    Opis:
    The present work is aimed at geometrical optimization and optical analysis of a small-sized parabolic trough collector (PTC). Improving the performance of parabolic trough collectors can greatly justify the use of solar energy. An optimized curvature geometry, the location of the absorber tube, and the heat flux distribution along the circumference of the absorber tube are major features in the geometric optimization and optical modelling of parabolic trough collectors. Rim angle, aperture width, the diameter of the absorber tube, receiver position, and the optimum value of heat flux are the major parameters considered in this work for geometrical and optical analysis. The Monte Carlo ray tracing method has been adopted for analysis. The non-uniform heat flux distribution profile obtained from optical analysis of the proposed parabolic trough collector has been compared with the profile available in the literature, and good agreement has been obtained, which proves the feasibility and reliability of the model and method used for this study. An experimental new small-sized parabolic trough collector has been fabricated for the optimized rim angle of 90 deg after a successful laser light feasibility test. The effect of the absorber tube position along the optical axis on the heat flux profile was analysed and found to be substantial. Furthermore, the sensitivity analysis of the parabolic trough collector using the software applied has been discussed separately.
    Źródło:
    Archives of Thermodynamics; 2023, 44, 3; 35--61
    1231-0956
    2083-6023
    Pojawia się w:
    Archives of Thermodynamics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Semantic web techniques for clinical topic detection in health care
    Autorzy:
    Raman, R.
    Sahayaraj, Kishore Anthuvan
    Soni, Mukesh
    Nayak, Nihar Ranjan
    Govindarajan, Ramya
    Singh, Nikhil Kumar
    Powiązania:
    https://bibliotekanauki.pl/articles/38698068.pdf
    Data publikacji:
    2024
    Wydawca:
    Instytut Podstawowych Problemów Techniki PAN
    Tematy:
    clinical text
    frequent word set
    feature selection
    clustering
    topic detection
    time sequence
    semantics
    tekst kliniczny
    częsty zestaw słów
    wybór funkcji
    grupowanie
    wykrywanie tematu
    sekwencja czasu
    semantyka
    Opis:
    The scope of this paper is that it investigates and proposes a new clustering method thattakes into account the timing characteristics of frequently used feature words and thesemantic similarity of microblog short texts as well as designing and implementing mi-croblog topic detection and detection based on clustering results. The aim of the proposedresearch is to provide a new cluster overlap reduction method based on the divisions ofsemantic memberships to solve limited semantic expression and diversify short microblogcontents. First, by defining the time-series frequent word set of the microblog text, a fea-ture word selection method for hot topics is given; then, for the existence of initial clusters,according to the time-series recurring feature word set, to obtain the initial clustering ofthe microblog.
    Źródło:
    Computer Assisted Methods in Engineering and Science; 2024, 31, 2; 139-155
    2299-3649
    Pojawia się w:
    Computer Assisted Methods in Engineering and Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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