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Wyświetlanie 1-15 z 28
Tytuł:
Synthesis of novel 2-mercapto-4-(p-aminophenyl sulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide derivatives via the Biginelli reaction
Autorzy:
Bhuva, N. H.
Gothalia, V. K.
Singala, P. M.
Talpara, P. K.
Faldu, V. J.
Shah, V. H.
Powiązania:
https://bibliotekanauki.pl/articles/412069.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
2-mercapto-4-(p-aminophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide
Biginelli condensation
Opis:
Series of 2-mercapto-4-(p-aminophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide Aa-h were synthesized via the biginelli condensation. 2-mercapto-4-amino-6-(aryl)-pyrimidine-5-carboxamide react with p-acetamidophenylsulphonylchloride in the presence of pyridine 2 to form 2-mercapto-4-(p-acetamidophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide 3. It was treated with diluted HCl under reflux afforded 2-mercapto-4-(p-aminophenylsulphonylamino)-6-(aryl)-pyrimidine-5-carboxamide A a-h. The newly synthesized compounds were characterized by elemental analyses, infrared (IR), 1H NMR and 13 C NMR spectroscopic investigation.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 17, 2; 168-173
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis, characterization of biologically potent novel chalcones bearing urea, thiourea and acetamide linkages
Autorzy:
Mewada, N. S.
Shah, D. R.
Chikhalia, K. H.
Powiązania:
https://bibliotekanauki.pl/articles/412032.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Chalcone
urea
thiourea
acetamide
antimicrobial activity and antifungal activity
Opis:
Three series of some novel chalcone based urea, thiourea and acetamide derivatives were designed, synthesized and screened for their antimicrobial and antifungal activities. All the synthesized compounds are first reported. The structures of the compounds were elucidated with the aid of elemental analysis and spectral methods including IR, 1H-NMR spectral data. The prepared compounds were evaluated for antibacterial activity against two Gram-positive bacteria (Staphylococcus aureus, Staphylococcus pyogenus), two Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli). The title compounds were also investigated for their antifungal activity using the broth micro dilution method. The bioassay results showed that compounds a few compounds showed good to superior in vitro antibacterial and antifungal activity.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 17, 3; 281-294
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis, characterization and docking studies of some novel xanthene derivatives
Autorzy:
Bhatt, Aditya H.
Shah, Viral R.
Rawal, Rakesh M.
Powiązania:
https://bibliotekanauki.pl/articles/1075739.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antimicrobial activity
Docking studies
Hantzsch synthesis
Xanthene
Opis:
The synthesis of a novel xanthene derivatives bearing dimedone as an excellent precursor has been achieved by applying one pot three component Hantzsch type condensation. The newly synthesized compounds were characterized by spectral and elemental analyses. All synthesized compounds undergo docking studies and biological screening for antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria and fungal species. Among all the tested compounds, it was found that compound 3c, 3d, 3g and 3h revealed better activities against the Gram-positive rather than the Gram-negative bacteria whereas results of docking studies revealed that compounds 3b, 3g and 3i showed best binding affinity towards ATP binding pocket of Human PIM1 kinase receptor through steric favorable and H-bond interactions.
Źródło:
World Scientific News; 2019, 118; 100-114
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis, Characterization and Biological evaluation of some newer 5-[6-chloro/fluoro/nitro-2-(p-chloro/ fluoro/ methyl phenyl)-quinolin-4-yl]-1,3,4-oxadiazole-2-thiols
Autorzy:
Faldu, V. J.
Talpara, P. K.
Bhuva, N. H.
Vachharajani, P. R.
Shah, V. H.
Powiązania:
https://bibliotekanauki.pl/articles/412197.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Quinolines
1,3,4-oxadiazole-2-thiols
therapeutic agents
antimicrobial assai
Opis:
Recent study shows that quinolines represent one of the most active classes of compounds possesses wide spectrum biodynamic activities and use as potent therapeutic agents. In present research work, 5-[6-chloro/fluoro/nitro-2-(p-chloro/fluoro/methyl phenyl)-quinolin-4-yl]-1,3,4-oxadiazole-2-thiols have been synthesized by condensation of substituted quinoline-4-carbohydrazides and mixture of carbon disulphide and potassium hydroxide. All of these compounds were screened for their in vitroanti microbial assay against gram (+ve), gram (-ve) bacteria and fungi activity compared with standard drugs viz., Ampicilin, Chloramphenicol, Ciprofloxacin, Norfloxacin, Griseofulvin and Nystatin at different concentrations.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 6; 26-32
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis, Characterization and Biological evaluation of 6-substituted-2-(substituted-phenyl)-quinoline derivatives bearing 4-amino-1,2,4-triazole-3-thiol ring at C-4 position
Autorzy:
Vaghasiya, R. G.
Ghodasara, H. B.
Vachharajani, P. R.
Shah, V. H.
Powiązania:
https://bibliotekanauki.pl/articles/412211.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Quinoline, 4-amino-1,2,4-triazole-3-thiol
therapeutic agents
antimicrobial assai
Opis:
Quinoline derivatives represent one of the most active classes of compounds possesses wide spectrum biodynamic activities and use as potent therapeutic agents. In this research work, a synthesis, characterization and biological evaluation of 6-substituted-2-(substituted-phenyl)-quinoline derivatives bearing 4-amino-1,2,4-triazole-3-thiol ring at C-4 position is described. The synthesis of quinoline derivatives is carried out by the reaction of substituted quinoline-4-carbohydrazides with a mixture of carbon disulphide and potassium hydroxide which further react with hydrazine hydrate to give final compounds. All of these compounds were screened for their in vitro antimicrobial assay against gram (+ve), gram (-ve) bacteria and fungi activity compared with standard drugs viz., Ampicilin, Chloramphenicol, Ciprofloxacin, Norfloxacin, Griseofulvin and Nystatin at different concentrations.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 8; 30-37
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and in vitro antimicrobial evaluation of amine substituted s-triazine based thiazolidinone/chalcone hybrids
Autorzy:
Shah, D. R.
Lakum, H. P.
Chikhalia, K. H.
Powiązania:
https://bibliotekanauki.pl/articles/412622.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Antibacterial
Antifungal
Chalcone
s-Triazine
4-thiazolidinone
Opis:
In an attempt to control multidrug resistant dilemma, a library of s-triazine based on two novel series of thiazolidinone (4a-e) and chalcone (7a-e) derivatives were designed and synthesized with simple and efficient etiquette. The newly synthesized compounds were studied for efficacy against several bacteria (Staphylococcus Aureus, Bacillus Cereus, Pseudomonas Aeruginosa, Klebsiella Pneumoniae,) and fungi (Candida Albicans, Aspergillus Clavatus) using the broth dilution technique. Compound 7d was the best bioactive desired antibacterial analogue with less MIC value against different tested strains. Results of bioassay study revealed the future hope of the potent drug-candidate based on s-triazine scaffold. All the final synthesized compounds were characterized by IR, 1 H NMR, 13 C NMR, mass and elemental analysis.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 17, 2; 207-219
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and characterization of some new Schiff bases of 2-oxonaphtho[2,1-b][1,4]oxazine
Autorzy:
Chovatiya, P.
Mehta, C.
Senjani, H.
Shah, A.
Joshi, H. S.
Powiązania:
https://bibliotekanauki.pl/articles/411737.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
2-Oxonaphtho[2,1-b][1,4]oxazine
Schiff base
Opis:
The literature review reveal that [1,4]-oxazine derivatives represent one of the most active classes of compounds possessing wide spectrum of biodynamic activities and use as potent therapeutic agents. In the present work, a series of Schiff base of 2-(2,3-dihydro-2-oxonaphtho[2,1-b][1,4]oxazin-1-yl)acetohydrazide, 5a-5j has been synthesized using 1-aminonaphthalen-2-ol. Various aromatic aldehyde were react with carbohydrazide 4 in the presence of acid to produce the 2-oxonaphtho[2,1-b][1,4]oxazin Schiff base derivatives with good yields. All synthesized compounds were characterized by IR, NMR and Mass spectrometry analysis.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 12; 26-30
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and antimicrobial screening of some new pyrimido[1,2-a]benzimidazole derivatives
Autorzy:
Shah, N. M.
Joshi, H. S.
Powiązania:
https://bibliotekanauki.pl/articles/411967.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
2-aminobenzimidazole
pyrimido[1,2-a]benzimidazole
chalcone
antimicrobial activity azoloazine
Opis:
Some new pyrimido[1,2-a]benzimidazole derivatives were synthesized by reacting 2-amino benzimidazole and chalcones in n-butanol at reflux temperature. In our present study we have used various heterocyclic chalcones derived from furfural and substituted acetophenones. All synthesized compounds were characterized by IR, 1H NMR and Mass spectroscopy. All synthesized compounds were screened for their antimicrobial activity against gram positive and gram negative bacteria which showed moderate to good activity.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 6; 56-60
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and antimicrobial activity of some new imidazolinone derivatives containing benzimidazole
Autorzy:
Mehta, P.
Davadra, P.
Shah, N.
Joshi, H.
Powiązania:
https://bibliotekanauki.pl/articles/411949.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
benzimidazole
imidazolinone
antimicrobial activity
Opis:
In this study some new o-benzimidazol-2'-yl-benzamido-p'-benzamido-2-phenyl-4-substituted phenyl-5-oxo-Imidazolines 3a-3j were synthesized. To synthesized target molecules we used various substituted oxazolone derivatives, synthesized from substituted benzaldehyde with hippuric acid. Substituted oxazolones 2a-2j were reacted with carbohydrazide derivative of benzimidazole 1 in presence of pyridine as base to obtained substituted imidazolinone derivatives. All synthesized compounds were characterized by IR, 1H NMR, elemental analysis and further supported by mass spectroscopy. All synthesized compounds were screened for their antimicrobial activity against gram positive and gram negative bacteria which showed moderate to good activity. All compounds showing good to moderate active against fungal strain as compare to standard drug.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 10; 74-80
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Software Startups – A Research Agenda
Autorzy:
Unterkalmsteiner, M.
Abrahamsson, P.
Wang, X. F.
Nguyen-Duc, A.
Shah, S.
Bajwa, S. S.
Baltes, G. H.
Conboy, K.
Cullina, E.
Dennehy, D.
Edison, H.
Fernandez-Sanchez, C
Garbajosa, J.
Gorschek, T.
Klotins, E.
Hokkanen, L.
Kon, F.
Lunesu, I.
Marchesi, M.
Morgan, L.
Oivo, M.
Selig, C.
Seppänen, P.
Sweetman, R.
Tyrväinen, P.
Ungerer, C.
Yagüe, A.
Powiązania:
https://bibliotekanauki.pl/articles/953060.pdf
Data publikacji:
2016
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
software startup
research agenda
software-intensive systems
Opis:
Software startup companies develop innovative, software-intensive products within limited time frames and with few resources, searching for sustainable and scalable business models. Software startups are quite distinct from traditional mature software companies, but also from micro-, small-, and medium-sized enterprises, introducing new challenges relevant for software engineering research. This paper’s research agenda focuses on software engineering in startups, identifying, in particular, 70+ research questions in the areas of supporting startup engineering activities, startup evolution models and patterns, ecosystems and innovation hubs, human aspects in software startups, applying startup concepts in non-startup environments, and methodologies and theories for startup research. We connect and motivate this research agenda with past studies in software startup research, while pointing out possible future directions. While all authors of this research agenda have their main background in Software Engineering or Computer Science, their interestin software startups broadens the perspective to the challenges, but also to the opportunities that emerge from multi-disciplinary research. Our audience is therefore primarily software engineering researchers, even though we aim at stimulating collaborations and research that crosses disciplinary boundaries. We believe that with this research agenda we cover a wide spectrum of the software startup industry current needs.
Źródło:
e-Informatica Software Engineering Journal; 2016, 10, 1; 89-123
1897-7979
Pojawia się w:
e-Informatica Software Engineering Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Optimal credit period and ordering quantity for credit dependent trended demand and deteriorating items with maximum lifetime
Autorzy:
Shah, N. H.
Shah, D. B.
Patel, D. G.
Powiązania:
https://bibliotekanauki.pl/articles/970075.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Instytut Badań Systemowych PAN
Tematy:
inventory
trended demand
trade credit
default risk
deterioration
maximum lifetime
Opis:
In this paper, an inventory system is analyzed regarding a trended demand. The seller offers its buyer a credit period for settling the account, which attracts more buyers and enhances market demand. However, the offer of credit period leads to default risk for the supplier. The units in inventory are deteriorating continuously and also have definite maximum lifetime. The aim is to maximize the profit of the retailer. Numerical examples are given to validate the developed mathematical model. Sensitivity analysis is performed to obtain the critical inventory parameters and deduce the managerial strategies.
Źródło:
Control and Cybernetics; 2015, 44, 2; 311-320
0324-8569
Pojawia się w:
Control and Cybernetics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Novel synthesis of 3-(((E)-benzylidene)amino)-5-((Z)-3,4-dimethoxybenzylidene)-2-phenyl-3,5-dihydro-4H-imidazol-4-one derivatives as potent antimicrobial agents
Autorzy:
Manawar, Rohit B.
Parmar, Mukesh B.
Nayaka, Indresh J.
Pandit, Brinda H.
Shah, Manish K.
Powiązania:
https://bibliotekanauki.pl/articles/1066261.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
4H-imidazol-4-one
A. niger
Anti-fungal
Anti-microbial Agent
Bioactivity
C. albicans
E. coli
Elemental analysis
IR spectroscopy
Mass spectroscopy
NMR spectroscopy
P. aeruginosa
S. aureus
S. pyogenes
Opis:
Novel synthesis of 4H-imidazol-4-one derivative by reaction of (Z)-3-amino-5-(3,4 dimethoxybenzylidene)-2-phenyl-3,5-dihydro-4H-imidazol-4-one with derivative of different aromatic aldehydes and Salicyldehyde. New synthesized compound are thermally stable and neither air-nor moisture sensitive at RT. Successive library of synthesized compound characterized using IR, NMR, Elemental, Mass, and its antimicrobial activity study.
Źródło:
World Scientific News; 2019, 130; 42-70
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Novel s-Triazinyl Schiff Base/Chalcone Congeners: Rational, Synthesis, Antimicrobial and Anti-TB Evaluation
Autorzy:
Lakum, H. P.
Shah, D. R.
Chikhalia, K. H.
Powiązania:
https://bibliotekanauki.pl/articles/412603.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
antimicrobial
Anti-TB
s-Triazine
Schiff base
Chalcone
Opis:
The occurrence of Multi Drug Resistant (MDR) infectious microbial strains has been increased upto alarming level which affects the public health worldwide. To cure this problem, a library of s-triazinyl derivatives comprising schiff base or chalcone motif have been rationalized, synthesized and screened for their in vitro antibacterial activity against five bacterial strains (Staphylococcus aureus MTCC 96, Bacillus subtilis MTCC 441, Escherichia coli MTCC 739, Pseudomonas aeruginosa MTCC 741 and Klebsiella pneumoniae MTCC 109) and four fungal strains (Aspergillus niger MTCC 282, Aspergillus fumigates MTCC 343, Aspergillus clavatus MTCC 1323, Candida albicans MTCC 183) using broth dilution technique. All the newly synthesized scaffolds were further evaluated for their in vitro anti-TB efficacy against the tubercular strain (Mycobacterium tuberculosis H37Rv) using Lowenstein-Jensen MIC method. All the derivatives were well characterized by IR, 1H NMR, 13C NMR, elemental analysis as well as mass spectroscopy.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 19, 1; 56-73
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Novel conversion of 4-aminoquinolines to new tricyclic (R,S)-3-methylazeto[3,2-c] quinolin-2(2aH)-ones and versatile one step synthesis of N-(quinolin-4-yl) carbamates from 4-aminoquinolines
Autorzy:
Kotadiya, V. C.
Viradiya, D. J.
Baria, B. H.
Kanzariya, J. S.
Kakadiya, R.
Shah, A.
Powiązania:
https://bibliotekanauki.pl/articles/412269.pdf
Data publikacji:
2014
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
quinolin
carbamates
azeto-quinolinone
aminoquinolines
Opis:
Reaction of 4-aminoquinolines with 4-nitrophenyl chloroformate have resulted in finding a novel transformation of 4-aminoquinolines to tricyclic (R,S)-3-methylazeto[3,2-c]quinolin-2(2aH)-ones. The structure of azeto-quinolinone was determined via spectroscopic and chemical methods. Various alcohols were used as nucleophiles to open the 1-azetinone ring to give the corresponding N-(quinolin-4-yl)carbamates in good yields. We also found a new and versatile one step synthesis of N-(quinolin-4-yl)carbamates by reacting 4-aminoquinolines with alkyl chloroformates in the presence of anhyd K2CO3 in acetonitrile.
Źródło:
International Letters of Chemistry, Physics and Astronomy; 2014, 11, 3; 265-276
2299-3843
Pojawia się w:
International Letters of Chemistry, Physics and Astronomy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Music Playlist Generation using Facial Expression Analysis and Task Extraction
Autorzy:
Sen, A.
Popat, D.
Shah, H.
Kuwor, P.
Johri, E.
Powiązania:
https://bibliotekanauki.pl/articles/908868.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
facial expression analysis
emotion recognition
feature extraction
viola jones face detection
gabor filter
adaboost
k-NN algorithm
task extraction
music classification
playlist generation
Opis:
In day to day stressful environment of IT Industry, there is a truancy for the appropriate relaxation time for all working professionals. To keep a person stress free, various technical or non-technical stress releasing methods are now being adopted. We can categorize the people working on computers as administrators, programmers, etc. each of whom require varied ways in order to ease themselves. The work pressure and the vexation of any kind for a person can be depicted by their emotions. Facial expressions are the key to analyze the current psychology of the person. In this paper, we discuss a user intuitive smart music player. This player will capture the facial expressions of a person working on the computer and identify the current emotion. Intuitively the music will be played for the user to relax them. The music player will take into account the foreground processes which the person is executing on the computer. Since various sort of music is available to boost one's enthusiasm, taking into consideration the tasks executed on the system by the user and the current emotions they carry, an ideal playlist of songs will be created and played for the person. The person can browse the playlist and modify it to make the system more flexible. This music player will thus allow the working professionals to stay relaxed in spite of their workloads.
Źródło:
Annales Universitatis Mariae Curie-Skłodowska. Sectio AI, Informatica; 2016, 16, 2; 1-6
1732-1360
2083-3628
Pojawia się w:
Annales Universitatis Mariae Curie-Skłodowska. Sectio AI, Informatica
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 28

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