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Wyświetlanie 1-5 z 5
Tytuł:
TYROSINASE INHIBITORY AND ANTIOXIDANT ACTIVITY OF WILD ROSA CANINA L. AND SORBUS AUCUPARIA L. FRUIT EXTRACTS
Autorzy:
Stanković, Milica I.
Savić, Vesna L.
Živković, Jelena V.
Stanojević, Ljiljana P.
Tadić, Vanja M.
Arsić, Ivana A.
Powiązania:
https://bibliotekanauki.pl/articles/895312.pdf
Data publikacji:
2019-06-28
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
antioxidants
polyphenols
Rosa canina L
Sorbus aucuparia L
anti-tyrosinase
Opis:
In the present work, fruits from two plant species, Rosa canina L. and Sorbus aucuparia L., popular in traditional folk medicine in Serbia, were studied. The aim was to examine and compare the efficiency of the ultrasonic extraction with different solvents regarding physicochemical properties, polyphenolic profile of extracts, as well as their tyrosinase inhibitory and antioxidant activity. The polyphenols evaluation indicated that water was the best solvent for a thorough extraction of bioactive compounds from the R. canina fruits, while propylene glycol-water (45:55, v/v) was the most efficient regarding S. aucuparia fruits, followed by ethanol-water (7:3, v/v). Only flavonoids were more abundant in S. aucuparia fruit extracts. R. canina water extracts showed a higher antioxidant activity, using several in vitro tests with different working principles. However, S. aucuparia ultrasonic extracts with propylene glycol-water (45:55, v/v) demonstrated a higher potential concerning tyrosinase inhibitory and chelating activity. Therefore, these ultrasonic extracts, being great sources of natural anti-tyrosinase inhibitors and antioxidants, can be considered as promising candidates suitable for pharmaceutical application, as great sources of natural anti-tyrosinase inhibitors and antioxidants.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 3; 523-533
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
THE INFLUENCE OF EXCIPIENTS ON STABILITY OF VISCOUS EYE DROPS WITH DEXPANTHENOL IN PHARMACEUTICAL PRACTICE
Autorzy:
Savić, Vesna L.
Živković, Jelena
Stanković, Milica I.
Antunović, Mirjana
Basić, Zorica
Nikolić, Ivana
Powiązania:
https://bibliotekanauki.pl/articles/895405.pdf
Data publikacji:
2019-10-30
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
dexpanthenol (DXP)
eye drops
viscosity
Carbopol® 940
stability
Opis:
Conventional eye drops exhibit weak bioavailability due to the unique physiology and anatomy of the eye. In order to increase eye drops viscosity, different concentrations of Carbopol® 940 (0.08% and 0.20%) were used. The aim of the study was to indicate the advantages and examine the influence of preservatives and the concentrations of viscosity increasing agents on the quality of magistral viscous eye drops with dexpanthenol (DXP). The quality of the prepared formulations was tested using physico-chemical methods and biological tests. pH Value measurement was done by the potentiometric method). Viscosity measurements of the samples were performed according to Ph. Eur. 9.0. DXP content was determined by reversed-phase high-pressure liquid chromatography. Sterility testing was performed using direct sample inoculation. The results indicate that pH values of eye drops with preservatives are lower than pH values of preservative-free formulations. All formulations have recovery values that meet the requirements of the European Pharmacopoeia. The DXP content in preservative-free eye drops increased slightly during testing, unlike the DXP content in eye drops with preservatives. The formulations remained sterile during 45 days after preparation, stored at room temperature, protected from light. DXP viscous eye drops may be prepared in pharmaceutical practice using the proposed viscosity increasing agent (Carbopol® 940) and preparation procedure. All formulations express stability for 45 days after preparation. Preservative-free DXP eye drops with Carbopol® 940 concentrations of 0.08% and 0.20% show maximal stability, provide an optimal concentration of DXP (3.0%), and therefore have an advantage in pharmaceutical practice.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 5; 845-853
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Statistical modeling of copper losses in the silicate slag of the sulfide concentrate smelting process
Autorzy:
Savic, M. V.
Djordjevic, P. B.
Mihajlovic, I. N.
Zivkovic, Z. D.
Powiązania:
https://bibliotekanauki.pl/articles/778781.pdf
Data publikacji:
2015
Wydawca:
Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:
modeling
copper concentrate
smelting process
copper losses
slag
ANFIS
Opis:
This article presents the results of the statistical modeling of copper losses in the silicate slag of the sulfide concentrates smelting process. The aim of this study was to define the correlation dependence of the degree of copper losses in the silicate slag on the following parameters of technological processes: SiO2, FeO, Fe3O4, CaO and Al2O3 content in the slag and copper content in the matte. Multiple linear regression analysis (MLRA), artificial neural networks (ANNs) and adaptive network based fuzzy inference system (ANFIS) were used as tools for mathematical analysis of the indicated problem. The best correlation coefficient (R2 = 0.719) of the final model was obtained using the ANFIS modeling approach.
Źródło:
Polish Journal of Chemical Technology; 2015, 17, 3; 62-69
1509-8117
1899-4741
Pojawia się w:
Polish Journal of Chemical Technology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Holographic Measurement of Dental Tissue Contraction and Stress, due to Postpolymerization Reaction
Autorzy:
Pantelić, D.
Blažić, L.
Savić-Šević, S.
Murić, B.
Vasiljević, D.
Panić, B.
Belić, I.
Powiązania:
https://bibliotekanauki.pl/articles/2047904.pdf
Data publikacji:
2007-11
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
42.40.Kw
87.85.G-
87.15.rp
87.10.Kn
Opis:
Polymerization contraction of dental photo-polymer composites induces internal stress, in a tooth cavity. This stress is measured indirectly by, first, holographic determination of tooth deformation, with consequent calculation of stress using finite element method. Real time holographic technique enabled observation of dental deformation in all stages of polymerization. Specially constructed blue-LED light source was used to polymerize photopolymer composite. We have found that polymerization continues even after illumination is over. Consequently, stress is increased, too.
Źródło:
Acta Physica Polonica A; 2007, 112, 5; 1157-1160
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Carrier Dynamics in Quantum Cascade Lasers
Autorzy:
Harrison, P.
Indjin, D.
Jovanović, V. D.
Mirčetić, A.
Ikonić, Z.
Kelsall, R. W.
McTavish, J.
Savić, I.
Vukmirović, N.
Milanović, V.
Powiązania:
https://bibliotekanauki.pl/articles/2041634.pdf
Data publikacji:
2005-01
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
42.60.-v
Opis:
A fully quantum-mechanical model for carrier scattering transport in semiconductor intersubband devices was applied to modelling of carrier dynamics in quantum cascade lasers. The standard model uses the envelope function and effective mass approximations to solve electron band structure under an applied bias. The k·p model has been employed in p-type systems where the more complex band structure requires it. The resulting wave functions are then used to evaluate all relevant carrier-phonon, carrier-carrier and alloy scattering rates from each quantised state to all others within the same and the neighbouring period. This piece of information is then used to construct a rate equation for the equilibrium carrier density in each subband and this set of coupled rate equations are solved self-consistently to obtain the carrier density in each eigenstate. The latter is a fundamental description of the device and can be used to calculate the current density and gain as a function of the applied bias and temperature, which in turn yields the threshold current and expected temperature dependence of the device characteristics. A recent extension which includes a further iteration of an energy balance equation also yields the electron (or hole) temperature over the subbands. This paper will review the method and describe its application to mid-infrared and terahertz, GaAs, GaN, and SiGe cascade laser designs.
Źródło:
Acta Physica Polonica A; 2005, 107, 1; 75-81
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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