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Wyszukujesz frazę "Salgado, M.V." wg kryterium: Autor

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    Wyświetlanie 1-3 z 3
    Tytuł:
    Structural Equation Modelling in the exploration and analysis of intrauterine environmental exposures with infant health effects
    Autorzy:
    Salgado, M.A.V.
    Bastias, M.
    Schisterman, E.
    Pino, P.
    Bangdiwala, S.
    Iglesias, V.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085142.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    structural equation model
    cohort study
    arsenic
    Chile
    intrauterine exposure
    Opis:
    Introduction. In epidemiology, generalized linear models are the main statistical methods used to explore associations. However, the use of other methods such as Structural Equation Modelling (SEM) is gradually increasing. Objective. The aim of the study was to illustrate the use of SEM in the assessment of salivary cortisol concentration in infants as a biomarker of perinatal exposure to inorganic arsenic. Materials and method. This was a cohort study of pregnant women recruited from public health care centres in Arica, Chile, in 2013. Socio-demographic information and urine samples to assess inorganic arsenic were collected during the second trimester of pregnancy. Saliva samples were collected to assess cortisol in infants between 18–24 months of age. Four linear regression models (LRMs) and two SEMs were run to estimate the effect of prenatal exposure to inorganic arsenic on cortisol concentration in infants. Results. According to LRMs and SEMs, prenatal exposure to inorganic arsenic and salivary cortisol were not associated. However, the association between maternal cortisol and cortisol in infants was statistically significant in all models; for each increase in standard deviation of the covariate Ln(maternal cortisol), the outcome Ln(cortisol in infant) increased by 0.49 units of variance in both SEMs. Conclusions. LRMs and SEMs were useful to assess the effect of prenatal exposure to inorganic arsenic on cortisol in infants. However, SEM allowed the adjustment of estimations by an estimated latent that obtained the information about income, occupation, education and ethnicity in a more comprehensive way than achieved by LRM.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 617-622
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Is prenatal arsenic exposure associated with salivary cortisol in infants in Arica, Chile? An exploratory cohort study
    Autorzy:
    Salgado, M.A.V.
    Schisterman, E.
    Pino, P.
    Bangdiwala, S.
    Munoz, M.P.
    Iglesias, V.
    Powiązania:
    https://bibliotekanauki.pl/articles/2083226.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    environmental exposure
    arsenic
    pregnant women
    cohort study
    Chile
    Opis:
    Introduction. In animal models, gestational exposure to inorganic arsenic has been associated with higher corticosterone concentration and consequent impairment of stress control in offspring. An equivalent association relating cortisol, a glucocorticoid hormone, in humans has not been previously studied. Objective. The aim of the study was to explore the association between prenatal inorganic arsenic exposure and salivary cortisol in infants from Arica, Chile. Materials and method. A cohort study of 168 mother-child dyads was recruited. In the 2nd trimester of pregnancy, urinary inorganic arsenic was assessed; 18–24 months after delivery, salivary cortisol was measured in the children. Maternal cortisol, maternal depression, stress, and socio-economic status were also evaluated. Results. The adjusted association was estimated with multiple linear regression after evaluating confounding through a directed acyclic graph. Median urinary inorganic arsenic in pregnant women was 14.1 μg/L (IQR: 10.4–21.7) while salivary cortisol in the children was 0.17 μg/L (IQR: 0.11–0.38). Among children from the highest income families (> 614 USD/month), arsenic exposure was associated with salivary cortisol. Children in the third quartile of arsenic exposure had -0.769 units of the logarithm of salivary cortiso, compared with those in the first quartile (p = 0.045). Conclusions. In this sample, prenatal exposure to arsenic was associated with salivary cortisol (third quartile of inorganic arsenic), only in infants belonging the highest income strata (> 614 USD). More studies are needed to confirm these preliminary results.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 2; 266-272
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association between coal and firewood combustion and hospital admissions and mortality in Chile 2015 - an ecological approach
    Autorzy:
    Paredes, M.C.
    Munoz, M.P.
    Salgado, M.V.
    Maldonado, A.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085865.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    air pollution
    biomass
    mortality
    hospitalization rate
    Opis:
    Introduction and objective. Burning coal and firewood generates toxic emissions that are associated with respiratory illness, cardiovascular disease, and even death. The aim of the study is to evaluate the association between county-level prevalence of household coal and firewood use and health outcomes, including total, respiratory, and cardiovascular mortality, as well as total and respiratory hospitalization rates. Materials and method. The ecological study included data on the use of household coal and firewood in 139 counties obtained from the 2015 Chilean National Socio-economic Characterization Survey. Total, respiratory, and cardiovascular mortality, as well as total and respiratory hospitalization rates, were obtained from the Department of Health Statistics. Poisson models with robust error variance, Pearson linear correlation coefficients, and scatterplots were used to explore associations between household coal and firewood use and morbidity-mortality, stratifying by geographic zone. Results. Total, respiratory, and cardiovascular mortality and total and respiratory hospitalization rates were 5.7 per 1,000, 552 per 100,000, 157 per 100,000, 92.5 per 1000, and 8.8 per 1000 inhabitants, respectively. The median prevalence of coal use for residential cooking, heating, or water heating was 3.64%, while the median prevalence of firewood combustion was 12%. In southern counties, age- and gender-adjusted respiratory mortality increased 2.02 (95% CI: 1.17–3.50), 1.5 (95% CI: 1.11–1.89), and 1.76-fold (95% CI: 1.19–2.60) for each percentage increase in household coal and firewood use for heating, cooking and heating water, respectively. Conclusions. The prevalence of household coal and firewood used for heating and cooking was positively correlated with respiratory mortality and hospitalization in southern zone counties.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 418-426
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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