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Wyświetlanie 1-4 z 4
Tytuł:
A review on metabolites and pharmaceutical potential of food legume crop mung bean (Vigna radiata L. Wilczek)
Autorzy:
Mehta, N.
Rao, P.
Saini, R.
Powiązania:
https://bibliotekanauki.pl/articles/2096785.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
bioactivity
medicinal property
metabolites
mung bean
nutritional value
phytochemicals
Opis:
Mung bean or moong or green gram, an important grain legume, is cultivated mainly in Asian countries and other parts of the world as a food crop. It is a highly nutritious grain legume with a high content of easily digestible proteins (20–32%), carbohydrates (53.3–67.1%), lipids (0.71–1.85%), vitamins, minerals, and fiber. It also contains some antinutrients such as tannins, phytic acid, hemagglutinin, polyphenols, and trypsin inhibitors in low concentrations. The sprouting of seeds leads to dynamic changes in metabolites with a decrease in antinutrient content and an increase in the nutritional value. In addition to these nutrients and antinutrients, the plant also contains various other phytochemicals such as alkaloids, flavonoids, saponins, phenols, glycosides, and bioactive peptides, which exhibit an array of pharmaceutically important properties such as anti-inflammatory, antinociceptive, antimicrobial, antioxidant, antidiabetic, lipid metabolism regulation, antihypertensive, antiallergic, and antitumor. Being rich in nutritional value and other phytochemical components, the plant can be explored further for its pharmaceutical properties and used as an efficient food additive in the preparation of different types of dietary supplements or food-derived drugs.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2021, 102, 4; 425-435
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
FORMULATION AND IN VIVO PHARMACOKINETIC STUDIES OF ILOPERIDONE DEPOT INJECTION
Autorzy:
Dubey, Vineet
Saini, Tulsi R.
Powiązania:
https://bibliotekanauki.pl/articles/895464.pdf
Data publikacji:
2019-02-28
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Iloperidone
in vivo pharmacokinetic studies
in situ depot injection
sucrose acetate isobutyrate
Opis:
Iloperidone is a new antipsychotic agent having a good tolerability and side-effects profile with respect to long term drug administration. Presently, it is only available as tablet dosage forms of 1-12 mg strengths for twice a day administration. This article reports the pharmacokinetic studies of a novel in situ depot injection formulation of iloperidone developed for once a month administration. The formulation is based on the use of sucrose acetate isobutyrate as gelling agent for depot formation in situ. It is simple to prepare, possesses an acceptable syringeability and exhibits a controlled and consistent zero order drug release in vitro for one month. The in vivo pharmacokinetic studies performed in male albino Wistar rats for one month showed a mean peak plasma drug concentration of 871.8 ng/ml in 3 days, mean residence time of 28.9 days, terminal half-life of 24 days, and a terminal elimination rate-constant of 0.0289/day. The plasma concentration profile of the developed formulation demonstrated a persistent plasma level of iloperidone for one month without any significant burst release and with a good in vitro - in vivo correlation.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 1; 59-66
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biochemical and structural studies of plant circadian clock proteins
Autorzy:
Saini, R.
Szpotkowski, K.
Kozak, M.
Jaskolski, M.
Davis, S.J.
Powiązania:
https://bibliotekanauki.pl/articles/80840.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
circadian clock
diurnal change
plant circadian clock
protein
multiple feedback loop
crystallization
recombinant fusion protein
early flowering
small angle X-ray scattering
protein-protein interaction
biochemical study
structural study
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of phytochemical constituents and antioxidant potential of hydro-alcoholic and aqueous extracts of Murraya koenigii L. and Ficus carica L.
Autorzy:
Farooq, S.A.
Singh, R.
Saini, V.
Powiązania:
https://bibliotekanauki.pl/articles/2048978.pdf
Data publikacji:
2019
Wydawca:
Instytut Włókien Naturalnych i Roślin Zielarskich
Tematy:
antioxidant activity
Ficus carica
Murraya koenigii
aktywność antyoksydacyjna
Opis:
Introduction: Murraya koenigii L. and Ficus carica L. have been traditionally used in folk medicine for treating several diseases. Objective: The present study was proposed to investigate the phytochemical constituents and antioxidant potential of hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica. Methods: Phytochemical screening was performed using different methods and antioxidant activity was evaluated by measuring total phenolic content, total antioxidant capacity (TAOC), hydrogen peroxide (H2O2) scavenging activity, DPPH radical-scavenging activity, reducing power assay, nitric oxide radical scavenging activity, and superoxide radical-scavenging activity. Results: The results showed that the hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica possess a significant quantity of flavonoids, saponins, terpenoids (9.0%, 0.9%, 0.6% and 7.3%, 8.7%, 0.44%, respectively) and also possess a significant antioxidant activity as evaluated by employing different antioxidant assays. Conclusion: It may be concluded that the hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica exhibit significant antioxidant activity.
Źródło:
Herba Polonica; 2019, 65, 4; 7-17
0018-0599
Pojawia się w:
Herba Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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