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Wyświetlanie 1-2 z 2
Tytuł:
Vaginal biocoenosis examining comparing to exfoliative cervical cytology
Autorzy:
Hawryluk, M.
Ustymowicz, W.
Hawryluk, L.
Maciorkowska, M.
Prycznicz, A.
Powiązania:
https://bibliotekanauki.pl/articles/1918532.pdf
Data publikacji:
2017-11-12
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Bacterial infections
Candida sp
cervical cytology
Trichomonas vaginalis
vaginal biocoenosis
Opis:
Introduction: At present, the gynaecologists have been increasingly frequently switching from vaginal biocoenosis assessment towards cervical cytology results to obtain information on the type of infection. Exfoliative cervical cytology is a screening test for dysplastic intraepithelial lesions and ectocervical cancers. One should emphasize however that one of the four parts of the new Bethesda classification specifies such inflammatory lesions as: Trichomonas vaginalis, Candida, Actinomyces, Chlamydia, cellular changes consistent with HSV infection and changes of bacterial flora. The gynaecologists however may perform vaginal biocoenosis assessment individually and diagnose its abnormalities in a relatively short timeframe.Conclusions: Lack of 100% correlation between the vaginal biocoenosis test and cytological result according to the Bethesda system means that assessment of vaginal microflora in phase-contrast microscopy should not be abandoned. Purpose: To analyse the association between lesions revealed during vaginal biocoenosis assessment in correlation to lesions described in the studies dedicated to cytological assessment of ectocervical smear. Material and methods: The study group included 1991 female patients scheduled for the follow-up cytological screening in a gynaecological office. Patients underwent gynaecological examination covering external areas, colposcopy, vaginal pH measurement, sampling for vaginal biocoenosis assessment purposes and cytological sampling. Results: It was demonstrated that diagnostic conformity for Candida sp accounted for only 17.2%, changes of bacterial flora for only 4% and – in the case of Trichomonas vaginalis - for only 3.9%. According to observations, bacterial infections and candidiases have been more frequently diagnosed during vaginal biocoenosis examining comparing to cytological screening, whereas infections with Trichomonas vaginalis have been more frequently diagnosed in cytological screening. Conclusions: Lack of 100% correlation between the vaginal biocoenosis test and cytological result according to the Bethesda system means that assessment of vaginal microflora in phase-contrast microscopy should not be abandoned.
Źródło:
Progress in Health Sciences; 2017, 7(2); 36-42
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of expression of selected proteins in the cells of intestinal and diffuse type gastric cancer – immunohistochemical analysis
Autorzy:
Gryko, M.
Prycznicz, A.
Dawidziuk, T.
Zińczuk, J.
Cepowicz, D.
Kamocki, Zb.
Kedra, B.
Guzińska-Ustymowicz, K.
Powiązania:
https://bibliotekanauki.pl/articles/1916399.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
gastric cancer
apoptosis
Lauren classification
E-cadherin
apoptotic pathways
Opis:
Introduction: Despite the progress in gaining knowledge about carcinogenesis, it is still unclear what processes are directly responsible for the differentiation of gastric cancer into its intestinal or diffuse form. Dividing of these two forms is based on one of the oldest, yet still commonly used classifications – the classification of Lauren. There are many factors that may influence the formation of gastric tumors of various aggressiveness. Purpose: To evaluate the expression of proteins: fragile histidine triad (FHIT), E-cadherin, α-catenin, γ-catenin, cathepsin B, epidermal growth factor (EGF), HER-2, MMP-9, MCM-2, Bak, Bax, BID, Bcl-XL, p53, FasL, Bcl-2, caspase-8, procaspase-3 in gastric cancer cells, depending on the type of tumor by Lauren classification. Materials and methods: Study group consisted of 91 patients treated surgically for gastric cancer in the Second Department of General and Gastroenterological Surgery, Medical University of Bialystok in years between 2000 and 2006. Results: It is shown, that the expression of E-cadherin was significantly higher in the Lauren I gastric cancer cells than in Lauren II. In case of caspase-8 there has been significantly less frequent expression of this protein in Lauren I gastric cancer cells compared to Lauren II. The authors describe no statistically significant differences in the expression of other proteins taken into consideration. Conclusions: These results suggest the role of adhesion and apoptosis-related proteins in the development of two different types of gastric cancer according to Lauren’s classification.
Źródło:
Progress in Health Sciences; 2014, 4, 1; 158-164
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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