- Tytuł:
- Prp4 kinase is required for proper segregation of chromosomes during meiosis in Schizosaccharomyces pombe
- Autorzy:
-
Pozgajova, Miroslava
Cipak, Lubos
Trakovicka, Anna - Powiązania:
- https://bibliotekanauki.pl/articles/1039511.pdf
- Data publikacji:
- 2013
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
Prp4 protein kinase
S. pombe
meiosis
segregation
protein phosphorylation - Opis:
- Chromosome segregation during meiosis is a complex process, which leads to production of four haploid gametes from two precursor cells. Reversible phosphorylation of proteins plays a crucial role in this process. The Schizosaccharomyces pombe Prp4 is an essential serine/threonine protein kinase, which belongs to the Clk/Sty family. To study the role of Prp4 in meiosis, we analysed chromosome segregation in a strain carrying conditional analog-sensitive allele of Prp4 protein kinase (prp4-as2). Our data show, that Prp4 protein kinase plays important role in chromosome segregation during meiosis, as revealed by enhanced missegregation of chromosomes in prp4-as2 mutant cells.
- Źródło:
-
Acta Biochimica Polonica; 2013, 60, 4; 871-873
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł