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Wyświetlanie 1-10 z 19
Tytuł:
Molecular evolution and phylogenetic implications in clinical research
Autorzy:
Podsiadlo, L.
Polz-Dacewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/49974.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
A phylogenetic tree shows graphically the evolutionary relationships among various organisms. The dynamic development of molecular biology and bioinformatics has led to a revolution in our knowledge of biological evolution and the kinships between living organisms and viruses. Nowadays, the available laboratory techniques and computer software allow reconstruction of the actual changes which occurred in the evolutionary process. The derivation of molecular evolution models and several methods for building phylogenetic trees have played a huge role in that enterprise. The emergence of new infectious agents is a problem afflicting mankind since prehistoric times. The study of phylogenetic implications among pathogenic microorganisms allows tracking the process of evolution, the indirect understanding of their biology, and thus facilitates the implementation of treatment. The presented article demonstrates the basic methods for constructing phylogenetic trees, as well as the benefits of reconstructing the evolution process and kinship with the study of microorganisms; in particular, viruses are considered from the clinical aspect.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of microRNA (miRNA) as a biomarker in HPV and EBV-related cancers
Autorzy:
Kolesnik, M.
Stepien, E.
Polz-Dacewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/2098505.pdf
Data publikacji:
2021
Wydawca:
Instytut Medycyny Wsi
Tematy:
biomarker
nucleotide sequence
cancer
cardiovascular disease
microRNA
Epstein-Barr virus
human papillomavirus
Opis:
Introduction and objective. Biomarkers are measurable biological indicators of many disease states. Particularly noteworthy are short nucleotide sequences involved in the regulation of many cellular processes. Their level in body fluids constitutes an important biological marker of serious diseases, such as cancer or cardiovascular diseases. For example, different types of microRNA may be used as biomarker in virus-associated cancers. The aim of this article was to review the current knowledge on the miRNAs and their role in viral-related cancers (EBV and HPV). The article reviews information available in journals and on electronic databases. Brief description of the state of knowledge. A significant part of the world’s population hosts at least one of the oncoviruses, but only a small percentage of them undergo a cancerogenesis to which these infectious agents contribute. Interaction between the host cell and viral factors can lead to the origination of a microenvironment favourable to oncogenesis. Cancer arises as a result of dysregulation in many cellular processes, and particularly important are short RNA sequences which regulate the processes that can cause this disease. The varied expression of this ribonucleic acid contributes to many diseases and provides valuable information about health. Importantly, these molecules are differentially expressed in virally-induced cancer. Many publications have confirmed the relationship between the expression of specific types of miRNA and cancers associated with EBV and HPV. Conclusions. The use of miRNAs as biomarkers of neoplastic diseases associated with EBV and HPV infections may significantly contribute to the reduction of mortality caused by these viruses, and thanks to the development of modern technologies they are an attractive research object.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2021, 15, 2; 104-110
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Enteroviruses in water environment - a potential threat to public health
Autorzy:
Rajtar, B
Majek, M.
Polanski, L.
Polz-Dacewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/50650.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Tematy:
epidemiology
laboratory technique
public health
aquatic environment
water
enterovirus
Picornaviridae
Źródło:
Annals of Agricultural and Environmental Medicine; 2008, 15, 2
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of lithium and/or selenium on plasma amino acids profile in rats
Autorzy:
Kiełczykowska, M.
Musik, I.
Luchowska-Kocot, D.
Polz-Dacewicz, M.
Powiązania:
https://bibliotekanauki.pl/articles/28761873.pdf
Data publikacji:
2022
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2022, 29, 1; 136-142
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-10 z 19

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