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Wyświetlanie 1-4 z 4
Tytuł:
Chitosan-derivatives in combinations with selected porphyrinoids as novel hybrid materials for medicine and pharmacy
Autorzy:
Szczepański, Radosław
Gadomska, Laura
Michalak, Marek
Bakun, Paweł
Pawlak, Kacper
Gośliński, Tomasz
Ziegler-Borowska, Marta
Czarczyńska-Goślińska, Beata
Powiązania:
https://bibliotekanauki.pl/articles/1034035.pdf
Data publikacji:
2020
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
chitin
chitosan
hybrid materials
imaging
photodynamic therapy
porphyrinoids
Opis:
Chitosan and its derivatives are renewable biopolymers characterized by high biocompatibility; therefore, they are harmless to humans and allow immune tolerance and improved hydrophilicity. Moreover, chitosan has been the most studied of all polysaccharides used in biomedical applications during the last decade. Combinations of chitosan and porphyrinoid compounds in hybrid materials have revealed many potential applications for biomedical sciences. The main advantage of such materials is an increase in the solubility of porphyrinoids in body fluids and therefore greater release of singlet oxygen to the treated tissue. Chitosan-based drug delivery systems can improve the targeting of porphyrinoids and their release at predetermined locations and finally achieve desired therapeutic effects with minimal side effects. Hence, porphyrinoid-chitosan materials can be applied in drug delivery systems, cancer theranostics and magnetic resonance imaging. The combination of chitosan and porphyrinoids also appears useful in the healing and repairing of damaged organs, tissue engineering, regenerative medicine, as well as dressing materials. Huge benefits are related to the treatment of wounds, which has been presented for self-healing hydrogels based on chitosan and porphyrinoids. Furthermore, the chitosan/porphyrinoid combinations have revealed enormous benefits for antimicrobial photodynamic therapy.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 63-78
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości fizykochemiczne, biologiczne i aplikacyjne izocyjanków. Część 2., Zastosowanie w medycynie i materiałoznawstwie
Physicochemical, biological and application properties of isocyanides. Part 2., Medical and materials science applications
Autorzy:
Pawlak, Marta
Pobłocki, Kacper
Drzeżdżon, Joanna
Jacewicz, Dagmara
Powiązania:
https://bibliotekanauki.pl/articles/2200417.pdf
Data publikacji:
2023
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
isocyanides
medicine
pharmaceuticals
polymers
IBPs
izocyjanki
medycyna
farmaceutyki
polimery
Opis:
Isocyanides are compounds with a triple bond between a nitrogen atom and a carbon atom. Thanks to this structure, there is an electron lone pair on the carbon atom, which allows these compounds to participate in many reactions in organic chemistry. Due to their properties and the number of reactions in which they can participate, this group has been applied in medicine. Both natural and synthetic isocyanides have antifungal, antibacterial, antimalarial, antiviral and anticancer properties. The reactions involving them allow for a much simpler and faster synthesis of many pharmaceuticals. In addition, these compounds have application properties, making it possible to obtain polymers. Despite the polymerization of these compounds raising many objections, many polymeric materials based on isocyanides have found applications both in science and in everyday life.
Źródło:
Wiadomości Chemiczne; 2023, 77, 3-4; 239--256
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości fizykochemiczne, biologiczne i aplikacyjne izocyjanków. Część 1., Pochodzenie, otrzymywanie i reakcje chemiczne
Physicochemical, biological and application properties of isocyanides, Part 1., Origins, derivation and chemical reactions
Autorzy:
Pawlak, Marta
Pobłocki, Kacper
Drzeżdżon, Joanna
Jacewicz, Dagmara
Powiązania:
https://bibliotekanauki.pl/articles/2200424.pdf
Data publikacji:
2023
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
isocyanides
isocyanates
isonitriles
electrophile nucleophile
reactions of isocyanides
izocyjanki
izocyjaniany
izonitryle
elektrofil
nukleofil
reakcje izocyjanków
Opis:
Isocyanides are the most unusual and unique group in organic chemistry. They possess an unusual valence structure and reactivity. Isocyanides are the only class of stable organic compounds with a formal divalent carbon, which allows them to be the subject of virtually all reactions in organic chemistry. It can be either an electrophile, a nucleophile, a caraben and a radical acceptor. We distinguish between naturally occurring and synthetically produced isocyanides. Both groups of isocyanides have become recently the subject of scientific interest.
Źródło:
Wiadomości Chemiczne; 2023, 77, 3-4; 215--237
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości katalityczne i biomedyczne związków zawierających jony rutenu (II) oraz Rutenu (III)
Catalytic and biomedical properties of compound containing ruthenium (II) and ruthenium (III) ions
Autorzy:
Pobłocki, Kacper
Pawlak, Marta
Walczak, Juliusz
Drzeżdżon, Joanna
Jacewicz, Dagmara Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/27310039.pdf
Data publikacji:
2023
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
związki kompleksowe Ru(II)
związki kompleksowe Ru(III)
właściwości biomedyczne
właściwości katalityczne
Ru(II) complex compounds
Ru(III) complex compounds
biomedical properties
catalytic properties
Opis:
Ruthenium complexes appear in scientific publications mainly as catalysts in the olefins metathesis process. In this review, we want to indicate the research niche regarding the use of ruthenium(II) and ruthenium(III) complexes in other catalytic processes, i.e. polymerization or epoxidation of olefins and depolymerization. We would like to combine the catalytic properties of ruthenium(II,III) complex compounds with their biomedical activity due to the growing problem of drug resistance (including antibiotic resistance). Scientists have been designing new metallopharmaceuticals exhibiting biological activity for several years, therefore this requires a critical review of the literature. The main goal of designing new metallodrugs is to create compounds with new or stronger biological properties compared to free ligands. Ruthenium compounds are considered potential substitutes for known drugs. In particular, Ru(II) and Ru(III) based complexes have reduced toxicity and can be tolerated in vivo. In addition, a wide spectrum of ruthenium oxidation states, a different mechanism of action and the kinetics of ligand substitution increase the advantage over coordination complex compounds based on platinum. In conclusion, in this review, we will focus on the latest reports from the literature on the catalytic properties and biomedical activity of ruthenium(II) and ruthenium(III) chemical compounds.
Źródło:
Wiadomości Chemiczne; 2023, 77, 5-6; 569--595
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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