- Tytuł:
- The effect of Galleria mellonella hemolymph polypeptides on Legionella gormanii
- Autorzy:
-
Chmiel, Elżbieta
Palusinska-Szysz, Marta
Zdybicka-Barabas, Agnieszka
Cytryńska, Małgorzata
Mak, Paweł - Powiązania:
- https://bibliotekanauki.pl/articles/1039350.pdf
- Data publikacji:
- 2014
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
Legionella gormanii
Galleria mellonella
apolipophorin III
Atomic Force Microscopy - Opis:
- Among Legionella species, which are recognized to be pathogenic for humans, L. gormanii is the second prevalent causative agent of community-acquired pneumonia after L. pneumophila. Anti-L. gormanii activity of Galleria mellonella hemolymph extract and apolipophorin III (apoLp-III) was examined. The extract and apoLp-III at the concentration 0.025 mg/ml caused 75% and 10% decrease of the bacteria survival rate, respectively. The apoLp-III-induced changes of the bacteria cell surface were analyzed for the first time by atomic force microscopy. Our studies demonstrated the powerful anti-Legionella effects of the insect defence polypeptides, which could be exploited in drugs design against these pathogens.
- Źródło:
-
Acta Biochimica Polonica; 2014, 61, 1; 123-127
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł