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    Wyświetlanie 1-9 z 9
    Tytuł:
    Jawornica czy Jafornycia? O alternatywnym pochodzeniu nazwy oronimu z Beskidu Małego
    Jawornica or Jafornycia? Alternate Origin oronym from the Beskid Mały Mountains
    Autorzy:
    Płonka, Przemysław
    Powiązania:
    https://bibliotekanauki.pl/articles/2216078.pdf
    Data publikacji:
    2022
    Wydawca:
    Wadowickie Centrum Kultury im. Marcina Wadowity
    Tematy:
    Blueberry
    Illyrians
    Jawornica
    Ojkonym
    Oronym
    Rotacism
    Sycamore
    Transhumance
    Vallachian
    Borówka
    Ilirowie
    Ojkonim
    Oronim
    Rotacyzm
    Jawor
    Wołoszczyzna
    Opis:
    In Poland many toponyms, in particular oronyms (names of mountains) is of volochian origin. One of the most frequent ethymologic roots in Poland is the name of sycamore three (Acer pseudoplatanus L.), namely derivatives of Polish “jawor”. Following prof. Janusz Rieger and his studies on Polish valachisms we try to question the common view that the oronym “Jawornica” near Andrychów comes from the name of the sycamore, instead trying to support the opinion that it may come from “Jafornycia” which is a derivate of Valachian “Jafar”/”Jafer” meaning the green, leafy stems of a popular forest shrublet of eatable berries (the blueberry). We support this view i.a. by comparing it to the ethymology of another oronym – “Leskowiec”, of a better documented history.
    Źródło:
    Wadoviana. Przegląd historyczno-kulturalny; 2022, 25; 133-151
    1505-0181
    Pojawia się w:
    Wadoviana. Przegląd historyczno-kulturalny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Melanin synthesis in microorganisms - biotechnological and medical aspects
    Autorzy:
    Plonka, Przemyslaw
    Grabacka, Maja
    Powiązania:
    https://bibliotekanauki.pl/articles/1041196.pdf
    Data publikacji:
    2006
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    bacteria
    melanogenesis
    virulence
    protozoa
    myxomycetes
    fungi
    Opis:
    Melanins form a diverse group of pigments synthesized in living organisms in the course of hydroxylation and polymerization of organic compounds. Melanin production is observed in all large taxa from both Pro- and Eukaryota. The basic functions of melanins are still a matter of controversy and speculation, even though their adaptative importance has been proved. Melanogenesis has probably evolved paralelly in various groups of free living organisms to provide protection from environmental stress conditions, but in pathogenic microorganisms it correlates with an increased virulence. The genes responsible for melanization are collected in some cases within operons which find a versatile application in genetic engineering. This review sumarizes current views on melanogenesis in Pro- and Eukaryotic microorganisms in terms of their biotechnological and biomedical importance.
    Źródło:
    Acta Biochimica Polonica; 2006, 53, 3; 429-443
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Splenic melanosis in agouti and black mice
    Autorzy:
    Michalczyk-Wetula, Dominika
    Wieczorek, Justyna
    Płonka, Przemysław
    Powiązania:
    https://bibliotekanauki.pl/articles/1038982.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    agouti
    EPR
    hair cycle
    melanin
    spleen
    Opis:
    An interesting example of extradermal deposition of melanin in vertebrates, notably in mammals, is splenic melanosis. In particular, if the phenomenon of splenic melanosis is correlated with hair or skin pigmentation, it must reflect the amount and perhaps the quality of pigment produced in hair follicle melanocytes. The present paper is our first study on splenic pigmentation in mice of phenotype agouti. We used untreated mixed background mice C57BL/6;129/SvJ (black - a/a, agouti - A/a, A/A), and as a control - black C57BL/6 and agouti fur from 129/SvJ mice, Mongolian gerbils (Meriones unguiculatus) and golden hamsters (Mesocricetus auratus). After euthanasia skin and spleen was evaluated macroscopically, photographed and collected for further analysis using Fontana-Masson and hematoxylin-eosin staining and electron paramagnetic resonance (EPR) at X-band. Spleens of the agouti mice revealed splenic melanosis but were slightly weaker pigmented than their black counterparts, while the presence of pheomelanin was difficult to determine. The fur of both phenotypes was of similar melanin content, with the same tendency as in the spleens. The contribution of pheomelanin in the agouti fur was on the border of detectability by EPR. Histological and EPR analysis confirmed the presence of melanin in the melanotic spleens. The shape of the EPR signal showed a dominance of eumelanin in fur and in melanized spleens in both phenotypes of mice. Therefore, splenic melanosis does reflect the hair follicle pigmentation not only in black, but also in agouti mice.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 3; 457-463
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Extradermal melanin transfer? Lack of macroscopic spleen melanization in old C57BL/6 mice with de-synchronized hair cycle
    Autorzy:
    Michalczyk, Dominika
    Popik, Malgorzata
    Salwinski, Aleksander
    Plonka, Przemyslaw
    Powiązania:
    https://bibliotekanauki.pl/articles/1040595.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    lipofuscin
    Fontana-Masson staining
    melanin degradation
    spleen melanosis
    ageing
    hair cycle
    Opis:
    In quest of alternate, extradermal path of melanin transfer from skin to the visceral organs, we suggested that some portions of such melanin may be deposited in the spleen, which in young black C57BL/6 mice is often melanized. Here, we confirm these observation using young C57BL/6 female mice (up to 17 weeks) and show that this phenomenon cannot be observed in old animals where the hair cycle is not synchronized any more. The experiments were carried out both on spontaneous and depilation-induced hair cycle. We have checked it as a side-observation over many other experiments carried out on young and old C57BL/6 female mice (up to 2.5 years of life). The presence or absence of melanin in the spleens was checked macroscopically, and histologically by Fontana-Masson (FM) staining, and synchronization of the hair cycle - by standard histomorphometric analysis of the back skin hair follicles. In about 40% of old spleens black FM-stainable 'debris' could be found under closer histological examination. This study shows that, at least in part, the phenomenon of splenic melanosis in C57BL/6 mice can be correlated with the synchronized skin melanization parallel to the hair cycle progress, and that splenic melanin undergoes gradual degradation during the mouse life.
    Źródło:
    Acta Biochimica Polonica; 2009, 56, 2; 343-354
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Kinetics of increased generation of ·NO in endotoxaemic rats as measured by EPR.
    Autorzy:
    Plonka, Przemyslaw
    Chlopicki, Stefan
    Wisniewska, Magdalena
    Plonka, >Beata
    Powiązania:
    https://bibliotekanauki.pl/articles/1043458.pdf
    Data publikacji:
    2003
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    NO-metry
    DETC
    NOS
    eye
    septic shock
    oxidative stress
    Opis:
    Ferrous-diethyldithiocarbamate (Fe(DETC)2) chelate is a lipophilic spin trap developed for g·NO detection by electron paramagnetic resonance (EPR) spectroscopy. Using this spin trap we investigated the kinetics of ·NO production in endotoxaemia in rats induced by lipopolysaccharide (Escherichia coli, 10 mg/kg). The NO-Fe(DETC)2 complex was found to give a characteristic EPR signal, and the amplitude of the 3rd (high-field) component of its hyperfine splitting was used to monitor the level of ·NO. We found that in blood, kindey, liver, heart and lung ·NO production starts to increase as early as 2 h after LPS injection, reaches the maximum 6 h after LPS injection and then returns to basal level within further 12-18 h. Interestingly, in the eye bulb the maximum of ·NO production was detected 12 h after LPS, and the signal was still pronounced 24 h after LPS. In brief, the highly lipophilic exogenous spin trap, Fe(DETC)2 is well suited for assessment of ·NO production in endotoxaemia. We demonstrated that the kinetics of increased production of ·NO in endotoxaemic organs, with the notable exception of the eye, do not follow the known pattern of NOS-2 induction under those conditions. Accordingly, only in early endotoxaemia a high level of ·NO is detected, while in late endotoxaemia ·NO detectability is diminished most probably due to concomitant oxidant stress.
    Źródło:
    Acta Biochimica Polonica; 2003, 50, 3; 807-813
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    X-band and S-band EPR detection of nitric oxide in murine endotoxaemia using spin trapping by ferro-di(N-(dithiocarboxy)sarcosine).
    Autorzy:
    Plonka, Przemyslaw
    Wisniewsk, Magdalena
    Chlopicki, Stefan
    Elas, Martyna
    Rosen, Gerald
    Powiązania:
    https://bibliotekanauki.pl/articles/1043457.pdf
    Data publikacji:
    2003
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    NO-metry
    DTCS
    NOS
    septic shock
    lung injury
    oxidative stress
    Opis:
    Ammonium salt of N-(dithiocarboxy)sarcosine (DTCS) chelated to ferrous salt was tested as an NO-metric spin trap at room temperature for ex vivo measurement of g·NO production in murine endotoxaemia. In a chemically defined in vitro model system EPR triplet signals of NO-Fe(DTCS)g2 were observed for as long as 3 hours, only if samples were reduced with sodium dithionite. This procedure was not necessary for the ex vivo detection of ·NO in endotoxaemic liver homogenates at X-band or in the whole intact organs at S-band, whereas only a weak signal was observed in endotoxaemic lung. These results suggest that in endotoxaemia not only high level of ·NO, but also the redox properties of liver and lung might determine the formation of complexes of ·NO with a spin trap. Nevertheless, both S- and X-band EPR spectroscopy is suitable for ·NO-metry at room temperature using Fe(DTCS)2 as the spin trapping agent. In particular, S-band EPR spectroscopy enables the detection of ·NO production in a whole organ, such as murine liver.
    Źródło:
    Acta Biochimica Polonica; 2003, 50, 3; 799-806
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Splenic melanosis during normal murine C57BL/6 hair cycle and after chemotherapy
    Autorzy:
    Michalczyk-Wetula, Dominika
    Salwiński, Aleksander
    Popik, Małgorzata
    Jakubowska, Monika
    Płonka, Przemysław
    Powiązania:
    https://bibliotekanauki.pl/articles/1039525.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cyclophosphamide
    Fontana-Masson
    hematoxylin and eosin
    May-Grünwald-Giemsa
    melanin
    spleen
    Opis:
    Cancer chemotherapy is associated with serious side effects, including temporary hair loss and impairment of pigmentation. We suspect that ectopic melanin deposition occurring due to chemotherapy may add to these effects worsening the already unpleasant symptoms. We associated the ectopic occurrence of follicular melanin after chemotherapy with splenic melanosis - an interesting example of extradermal melanin localization - and we expected an increase in splenic melanin deposition after chemotherapy. Using the C57BL/6 murine model of synchronized hair cycle induced by depilation, we visualized splenic melanin by means of several histological and histochemical protocols of staining: hematoxylin and eosin, May-Grünwald-Giemsa and Fontana-Masson. Unexpectedly, the splenic deposition of melanin decreased due to application of cyclophosphamide (i.p. 120 mg/ kg body weight on day 9 post depilation). The drop was abrupt and lasted for at least 5 days (day 13-18 post depilation), as compared with normal hair cycle. Moreover, in mice with normal, depilation-induced hair cycle we observed a similar drop shortly before entering catagen (day 15 post depilation), followed by a slow and partial increase in splenic melanization up to day 27 post depilation in both groups. We conclude that cyclophosphamide negatively affects splenic melanization and/or extradermal transfer of ectopic melanin from the dystrophic hair follicles, but the most powerful down-regulator of splenic melanosis is normal and dystrophic catagen - the phase of hair follicle involution and re-modelling.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 3; 313-321
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Splenic eumelanin differs from hair eumelanin in C57BL/6 mice.
    Autorzy:
    Plonka, Przemyslaw
    Michalczyk, Dominika
    Popik, Malgorzata
    Handjiski, Bori
    Slominski, Andrzej
    Paus, Ralf
    Powiązania:
    https://bibliotekanauki.pl/articles/1041424.pdf
    Data publikacji:
    2005
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    melanin degradation
    spin-lattice relaxation
    pigmentation
    hair cycle
    hair follicle
    EPR
    Opis:
    The presence of melanin in spleens of black C57BL/6 mice has been known for long. Although its origin and biological functions are still obscure, the relation of splenic melanin to the hair follicle and skin pigmentation was suggested. Here, we demonstrated using for the first time electron paramagnetic resonance spectroscopy that black-spotted C57BL/6 spleens contain eumelanin. Its presence here is a "yes or no" phenomenon, as even in the groups which revealed the highest percentage of spots single organs completely devoid of the pigment were found. Percentage of the spotted spleens decreased, however, with the progress of telogen after spontaneously-induced hair growth. The paramagnetic properties of the spleen eumelanin differed from the hair shaft or anagen VI skin melanin. The splenic melanin revealed narrower signal, and its microwave power saturability betrayed more heterogenous population of paramagnetic centres than in the skin or hair shaft pigment. Interestingly, the pigment of dry hair shafts and of the wet tissue of depilated anagen VI skin revealed almost identical properties. The properties of splenic melanin better resembled the synthetic dopa melanin (water suspension, and to a lesser degree - powder sample) than the skin/hair melanin. All these findings may indicate a limited degradation of splenic melanin as compared to the skin/hair pigment. The splenic eumelanin may at least in part originate from the skin melanin phagocyted in catagen by the Langerhans cells or macrophages and transported to the organ.
    Źródło:
    Acta Biochimica Polonica; 2005, 52, 2; 433-441
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pulmonary metastases of the A549-derived lung adenocarcinoma tumors growing in nude mice. A multiple case study
    Autorzy:
    Jakubowska, Monika
    Śniegocka, Martyna
    Podgórska, Ewa
    Michalczyk-Wetula, Dominika
    Urbanska, Krystyna
    Susz, Anna
    Fiedor, Leszek
    Pyka, Janusz
    Płonka, Przemysław
    Powiązania:
    https://bibliotekanauki.pl/articles/1039526.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    adenocarcinoma
    histological analysis
    metastases
    nude mice
    photodynamic therapy
    zinc pheophorbide a
    Opis:
    Lung adenocarcinoma is a leading human malignancy with fatal prognosis. Ninety percent of the deaths, however, are caused by metastases. The model of subcutaneous tumor xenograft in nude mice was adopted to study the growth of control and photodynamically treated tumors derived from the human A549 lung adenocarcinoma cell line. As a side-result of the primary studies, observations on the metastasis of these tumors to the murine lungs were collected, and reported in the present paper. The metastasizing primary tumors were drained by a prominent number of lymphatic vessels. The metastatic tissue revealed the morphology of well-differentiated or trans-differentiated adenocarcinoma. Further histological and histochemical analyses demonstrated the presence of golden-brown granules in the metastatic tissue, similar to these found in the tumor tissue. In contrast to the primary tumors, the electron paramagnetic resonance spectroscopy revealed no nitric oxide - hemoglobin complexes (a source of intense paramagnetic signals), in the metastases. No metastases were found in other murine organs; however, white infarctions were identified in a single liver. Taken together, the A549-derived tumors growing subcutaneously in nude mice can metastasize and grow on site in the pulmonary tissue. Thus, they can represent an alternative for the model of induced metastatic nodule formation, following intravenous administration of the cancerous cells.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 3; 323-330
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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