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    Tytuł:
    Effect of a medicinal agent, possessing antioxidant and antihypoxant properties, on the state of oxygen homeostasis and lipid peroxidation under experimental pneumoconiosis in albino rats
    Autorzy:
    Olyinyk, A.
    Ślifirczyk, A.
    Nikoniuk, M.
    Celiński, M.
    Domańska, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918832.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    experimental pneumoconiosis
    metho-dology of pneumoconiosis stimulation in albino rats
    lipid peroxidation
    oxygen metabolism
    ethylmethylhydroxypyridine succinate
    Opis:
    Introduction: Pneumoconioses (Pc) are interstitial pulmonary diseases of professional genesis, caused by long-term inhalation of high dust concentrations. Pcafflict 26.6-53% of the workers, exposed to dust contamination. The major feature of Pc course is irrevocability and incurability. Purpose: The research of the effect of ethylmethyl hydroxypyridine succinate, possessing antioxidant and antihypoxant characteristics, on the oxygen metabolism, acid-alkaline state, and lipid peroxidation at the background of experimental pneumoconiosis in albino rats. Material and methods: Pneumoconiosis was simulated on 72 albino rats through endotracheal injection of black coal suspension, on our own modification of O. Yu. Nykolenko methodology. Results: Manifestations of experimental pneumo-coniosis depended on the period of dust inhalation. Development of experimental pneumoconiosis was found to result in the decreased partial oxygen pressure in the arterial blood, compensated hyperventilation-induced respiratory alkalosis, and marked increase in lipid peroxidation activity that could be seen in the blood content of malon-dialdehyde, as well as of conjugated dienes and trienes. Conclusions: Application of ethylmethylhydroxy pyridine succinate in experimental pneumoconiosis has been found to improve oxygen metabolism, acid-alkaline state, and lipid peroxidation that is revealed in normalization of the partial oxygen pressure in the arterial blood, oxygen saturation of haemoglobin, index of bases’ deficiency BE (Ваse-Ехсеss), and in 1.6-2.0 decrease in the content of malondialdehyde, as well as of conjugated dienes and trienes.
    Źródło:
    Progress in Health Sciences; 2018, 8(2); 137-143
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The structure of clusters in liquid alloys of pseudo-binary PbTe-Bi2Te3 system
    Autorzy:
    Korolyshyn, A. V.
    Olyinyk, Z. M.
    Mudry, S. I.
    Powiązania:
    https://bibliotekanauki.pl/articles/378946.pdf
    Data publikacji:
    2019
    Wydawca:
    Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
    Tematy:
    metallic alloy
    short-range order
    melt
    thermoelectric material
    stop metaliczny
    uporządkowanie bliskie
    wytop
    materiał termoelektryczny
    Opis:
    Purpose: of this paper is to study the structure of melts of quasi-binary system Bi2Te3-PbTe by means of X-ray diffraction method. The aim of the research was to investigate the short range order in melts comparing it with the structure in solid state. Design/methodology/approach: Analysis of the structural factors, radial distribution functions of atoms and basic structural parameters showed that the structure of melts at temperatures near the liquidus shows microheterogeneity. Findings: On the basis of the analysis of structural factors, functions of the radial distribution of atoms and basic structural parameters, it is shown that in the given concentration the short range order structure of liquid alloys of pseudo-binary PbTe-Bi2Te3 system is microinhomogeneous and is characterized by the presence of associates, whose atomic arrangement is like to the structure of solid compounds, existing in this concentration range. Research limitations/implications: To complete the understanding of short-range order effect on the formation of the physical properties of Pb-Bi-Te alloys, further studies of the thermoelectric properties of these alloys in the liquid state are needed. Practical implications: The promise of the considered direction requires an experimental and theoretical study of the processes of bulk, thin film and nanostructured material. In this case, it is necessary to develop a technology for the synthesis of compounds of Pb-Bi-Te system, obtaining thin films and nanostructures using the vapour phase methods with studying the mechanisms of thermoelectric properties of the material formation and optimization of technological regimes for obtaining effective thermoelectric materials based on compounds of Pb-Te-Bi system. Originality/value: The processes of structure formation of nanosystems with given characteristics are investigated, because among numerous thermoelectric materials, bismuth telluride (Bi2Te3) and its alloys are the most important thermoelectric materials used in state-of-the-art devices near room temperature, and lead telluride (PbTe)-based alloys are extensively used in power supplies for space exploration and generators for use at medium to high temperatures.
    Źródło:
    Archives of Materials Science and Engineering; 2019, 100, 1/2; 5-12
    1897-2764
    Pojawia się w:
    Archives of Materials Science and Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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