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    Wyświetlanie 1-10 z 10
    Tytuł:
    Zasadzka
    Autorzy:
    Ogonowski, Jan "Junak".
    Powiązania:
    Zeszyty Kombatanckie 2004, nr 39, s. 69-72
    Data publikacji:
    2004
    Tematy:
    Wójcik, Tomasz
    Renner, Kurt
    Armia Krajowa. Okręg Radomsko-Kielecki. Oddział Partyzancki "Tarzana" NOW działania bojowe pamiętniki
    Pamiętniki żołnierskie polskie 1939-1945 r.
    Opis:
    Nieudana zasadzka w lesie pod Ożarowem. Zabicie gen. Kurta Rennera i żołnierzy Wehrmachtu.
    Fot.
    Dostawca treści:
    Bibliografia CBW
    Artykuł
    Tytuł:
    Production of triterpenoids with cell and tissue cultures
    Autorzy:
    Malinowska, Magdalena
    Sikora, Elżbieta
    Ogonowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1039476.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    biotransformation
    tritepenoids
    cell cultures
    microorganisms
    in vitro
    Opis:
    Triterpenes are group of biologically active compounds which can be found in higher plants. Their main source are plants bark, leaves, twigs, fruits, resins or oils. The biological activity of triterpens is very diversified and many studies have already confirmed the following therapeutic effects: anti-inflammatory, antimicrobial, antiviral, antifungial, immunomodulatory, and hepatoprotective. Synthesis of triterpenes derivates can be performed by chemical or enzymatic reactions, however biotransformation is more specific and eliminates the side products and the molecule alterations. These processes use isolated enzymes or microorganisms. Cell culture in vitro eliminates problems like extract variability as well as instability of the compounds being obtained during the extraction process. What is more, it ensures high reproducibility and optimal regio- and enantioselectivity. The most widely used technique is a classical screening of a series of microbial strains. Studies on triterpene biotransformation give a lot of information about new biologically active compounds and let predict the metabolism of biological compounds. This review presents most important advancements in the metabolic engineering of microorganisms for the production of triterpenoids. Moreover, the review highlights general strategies to obtain rich biochemical diversity of plants by employing the biocatalysts produced by microorganisms or tissue cultures.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 731-735
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Influence of process parameters on properties of Nanostructured Lipid Carriers (NLC) formulation
    Autorzy:
    Lasoń, Elwira
    Sikora, Elżbieta
    Ogonowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1039484.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    nanostructured lipid carriers
    NLC
    liquid lipids
    solid lipids
    ultrasonication
    Opis:
    Nanostructured lipid carriers (NLC) are stable colloidal formulations with notable advantages for drug delivery systems. Thanks to their physicochemical stability, biocompatibility, biodegradability and controlled drug release, they have received increasing attention for the last several years. The aim of the study was to prepare and characterize nanostructured lipid carriers (NLC). Both, the effect of the process parameters and the effect of the preemulsion composition on the NLC properties were investigated. In the work, different type of surfactants (i.e. decyl glucoside, Poloxamer188, Tween 80, sodium cholate) and their combinations were used to stabilize NLC dispersions. Moreover, several kinds of solid lipids (modified beeswax, gliceryl behenate, cetyl palmitate and berry wax) and liquid lipids (caprilic/capric triglyceride and decyl oleate) were applied. An ultrasonication method using a probe type sonicator was used to obtain NLC, and the time and energy of the process were modified throuhout. The physicochemical properties of the formulations, such as particle size, size distribution, polidispersity index were studied using the dynamic light scattering (DLS) method. The electrophoretic mobility of obtained particles was also measured, using the Zetasizer Nano ZS Malvern Instrument based on the Laser Doppler Velocimetry (LDV) technique. Knowing the value of electrophoretic mobility of particles for given conditions, the zeta potential was determined. The obtained results showed that the process parameters and the composition of the preemulsion had significant impact on the nanoparticles structure. The optimal formulations size ranged between 60 and 80 nm, and the value of their zeta potential was up to -30mV. The stability of these systems was further confirmed by macroscopic observation.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 773-777
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of selected supercritical CO2 plant extract addition on user properties of shower gels
    Autorzy:
    Vogt, Otmar
    Sikora, Elżbieta
    Ogonowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/778999.pdf
    Data publikacji:
    2014
    Wydawca:
    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
    Tematy:
    supercritical CO2 extract
    black currant seeds
    strawberry seeds
    hop cones
    mint leafs
    shower gel
    Opis:
    The formulations of washing cosmetics i.e. shower gels, containing extracts obtained during supercritical CO2 extraction process as active ingredient, were developed. The subject of the study was the analysis of the physicochemical and user properties of the obtained products. In the work supercritical CO2 extracts of black currant seeds, strawberry seeds, hop cones and mint leafs were used. The formulation contains a mixture of surfactants (disodium cocoamphodiacetate, disodium laureth sulfosuccinate, cocoamide DEA, cocoamidepropyl betaine, Sodium Laureth Sulfate). Various thickener agents were applied to the obtained desired rheological properties of the cosmetics. Among others, sorbitol acetal derivatives, methylhydroxypropylcellulose and C10-30 alkyl acrylate crosspolymer were used. For stable products, the effect of extracts addition (black currants seeds, strawberries seeds, mint and hops, obtained from supercritical CO2 extraction process) on the cosmetics properties, such as pH, viscosity, detergency and foam ability, were determined. The obtained results showed that the extracts could be used as components of shower gels.
    Źródło:
    Polish Journal of Chemical Technology; 2014, 16, 4; 51-54
    1509-8117
    1899-4741
    Pojawia się w:
    Polish Journal of Chemical Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Studies on the formation of O/W nano-emulsions, by low-energy emulsification method, suitable for cosmeceutical applications
    Autorzy:
    Jaworska, Małgorzata
    Sikora, Elżbieta
    Zielina, Michał
    Ogonowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1039485.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    nano-emulsions
    crodamol GTCC
    crodamol PC
    oleic acid
    Opis:
    The formation of oil/water (O/W) nano-emulsions suitable for cosmeceutical application was studied. Nano-emulsions were prepared by using phase inversion composition (PIC) method, one of the low-energy emulsification methods. The process consist of stepwise water addition to oil/surfactant mixture, at T = 25°C. Caprylic/capric triglycerides (GTCC), propylene glycol dicaprylate/dicaprate (PC) and oleic acid (OA) were applied as an oil phase. Polysorbate 80 was used as the surfactant. Kinetic stability of the nano-emulsions was analyzed by measuring droplet size as a function of time for different oil/surfactant ratio. The particles size distribution was analyzed by means DLS measurement technique (Dynamic Light Scattering), using Zetasizer Nano ZS (Malvern Instruments, UK). One of triterpenoic acid, practically non-water soluble substance was selected as an active and incorporated into the stable formulation. The obtained results proved that the nanoemulsion NE-T80-GTCC-20:80 based on caprylic/capric triglycerides with the oil/surfactant ratio O/S = 2 0:80 and the droplet size r = 25 nm was the most stable one and additionally showed the highest solubilisation capacity for the triterpene.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 779-782
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Study of O/W micro- and nano-emulsions based on propylene glycol diester as a vehicle for geranic acid
    Autorzy:
    Jaworska, Małgorzata
    Sikora, Elżbieta
    Ogonowski, Jan
    Konieczna, Monika
    Powiązania:
    https://bibliotekanauki.pl/articles/1039096.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    nano-emulsions
    microemulsion
    Crodamol PC
    geranic acid
    release profile
    Opis:
    Nano- and microemulsions containing as the oil phase caprylic/capric propylene glycol diesters (Crodamol PC) were investigated as potential vehicle for controlled release of geranic acid. The influence of emulsifiers and co-surfactants on stability of the emulsions was investigated. Different kind of polysorbates (ethoxylated esters of sorbitan and fatty acids) were applied as the emulsifiers. The short-chain alcohols (ethanol, 1-propanol, 1-butanol) were used as co-surfactants. The emulsions were prepared at ambient temperature (25°C), by the phase inversion composition method (PIC). The stable O/W high dispersed emulsion systems based on Crodamol PC, of mean droplets size less than 200 nm, were prepared. Microemulsions stabilized by the mixture of Polisorbat 80 and 1-butanol were characterized by the largest degree of dispersion (137 nm) and the lowest PDI value (0.094), at surfactant/co-surfactant: oil weight ratio 90:10. The stable nano-emulsion (mean droplet size of 33 nm) was obtained for surfactant: oil (S:O) weight ratio 90:10, without co-surfactant addition. This nano-emulsion was chosen to release studies. The obtained results showed that the prepared stable nano-emulsion can be used as a carrier for controlled release of geranic acid. The active substance release from the nano-emulsion and the oil solution, after 24 hours was 22%.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 2; 229-233
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Micelle-mediated extraction of elderberry blossom by whey protein and naturally derived surfactants
    Autorzy:
    Śliwa, Karolina
    Tomaszkiewicz-Potępa, Anna
    Sikora, Elżbieta
    Ogonowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1039492.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    whey protein concentrate
    micelle-mediated extraction
    elderberry-blossom
    Opis:
    Classical methods of the extraction of active ingredients from the plant material are expensive, complicated and often environmentally unfriendly. The micelle-mediated extraction method (MME) seems to be a good alternative. In this work, extractions of elderberry blossoms (Flos Sambuci) were performed using MME methods. Several popular surfactants and whey protein concentrate (WPC) was applied in the process. The obtained results were compared with those obtained in extraction by means of water. Antioxidant properties of the extracts were analyzed by using two different methods: reaction with di(phenyl)-(2,4,6-trinitrophenyl)iminoazanium (DPPH) reagent and Follin's method. Furthermore, the flavonoid content in the extracts was determined. The results confirmed that the MME method with using whey protein might be an alternative method for obtaining, rich in natural antioxidants, plant extracts.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 803-806
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A micelle mediated extraction as a new method of obtaining the infusion of Bidens tripartita
    Autorzy:
    Śliwa, Karolina
    Sikora, Elżbieta
    Ogonowski, Jan
    Oszmiański, Jan
    Kolniak-Ostek, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/1038779.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    ultrasonic assisted micelle-mediated extraction
    three-part beggarticks
    whey protein concentrate
    Opis:
    In this paper, the extracts of three-part beggarticks (Bidens tripartita) were prepared using ultrasonic assisted micelle-mediated extraction method (UAMME). Different kind of surfactants and WPC (whey protein concentrate) were applied. In the B. tripartita extracts twenty polyphenols were identified by UPLC-DAD-MS. Both aqueous and UAMME extracts mainly contained chlorogenic acid, caftaric acid and its derivatives as well as luteolin 7-O-glucoside. The luteolin was extracted with Rokanol B2 and Triton X-100. Furthermore, antioxidative properties of the extracts were analyzed with two methods: reactions with di(phenyl)-(2,4,6-trinitrophenyl)iminoazanium (DPPH) reagent and Follin's method. The DPPH radical scavenging by micellar extracts was in general comparable with the antioxidant activity of conventional extracts. The most active was sample with Tego Care CG90, reducing about 73% of the radical. Obtained results confirmed that the UAMME might be an alternative method, to the liquid-liquid or solid-liquid extraction, of obtaining specified extracts rich in active compounds. Selecting a suitable surfactant may thus provide the expected composition of the extract.
    Źródło:
    Acta Biochimica Polonica; 2016, 63, 3; 543-548
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    NLCs as a potential carrier system for transdermal delivery of forskolin
    Autorzy:
    Lasoń, Elwira
    Sikora, Elżbieta
    Miastkowska, Małgorzata
    Escribano, Elvira
    Garcia-Celma, Maria
    Solans, Conxita
    Llinas, Meritxell
    Ogonowski, Jan
    Powiązania:
    https://bibliotekanauki.pl/articles/1038376.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Forskolin
    NLC
    nanostructured lipid carrier
    skin permeation
    Opis:
    Nanostructured lipid carriers (NLC) composed of the substances generally recognized as safe (GRAS) were obtained by using a hot high-pressure homogenization technique (HPH). The influence of the number of homogenization cycles and concentration of a decyl glucoside surfactant on the NLC properties were studied. The system's stability was assessed by macroscopic observation, light backscattering and zeta potential measurements. NLC particle size was measured using dynamic light scattering (DLS). The kinetically stable formulations were loaded with forskolin and selected for in vitro drug permeation study using the Franz cell method. Concentration of forskolin in the receptor solution (i.e. ethanol/PBS mixture) was analyzed with high performance liquid chromatography (HPLC) with UV detection. The obtained results have shown that NLC formulations could be used as effective carriers for forskolin permeation through the skin.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 3; 437-442
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wydział Elektryczny Politechniki Gdańskiej dla Marynarki Wojennej
    Autorzy:
    Figwer, Jan.
    Powiązania:
    Przegląd Morski 2004, z. 10, s. 52-56
    Współwytwórcy:
    Ogonowski, Andrzej. Uzupełnienie
    Data publikacji:
    2004
    Tematy:
    Politechnika Gdańska. Wydział Elektryczny a Marynarka Wojenna współpraca 1952-1968 r.
    Okręty pole magnetyczne badanie
    Demagnetyzacja
    Opis:
    Uzup.:; Andrzej Ogonowski; Przegląd Morski; 2004; z. 10; s. 56-57.
    Dostawca treści:
    Bibliografia CBW
    Artykuł
      Wyświetlanie 1-10 z 10

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