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    Wyświetlanie 1-13 z 13
    Tytuł:
    Kościoły Środy Wielkopolskiej według akt wizytacji Franciszka Ksawerego Rydzyńskiego z 1777 roku
    Churches of Środa Wielkopolska According to the Acts of Visitation of Franciszek Ksawery Rydzyński from 1777
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1039376.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    Środa Wielkopolska
    kolegiata średzka
    kapituła kolegiacka w Środzie
    kaplica Gostomskich
    kaplica Grzymułtowskich
    kościół św. Idziego w Środzie
    kościół św. Sebastiana w Środzie
    kościół Wszystkich Świętych w Środzie
    kościół szpitalny Ducha Świętego
    diecezja poznańska
    archidiakonat poznański
    Hieronim Gostomski
    środa wielkopolska
    collegiate church in środa
    collegiate chapter in
    środa
    gostomscy’s chapel
    grzymułtowscy’s chapel
    the church of saint sebastian in środa
    the church of all saints in środa
    the hospital church of the holy spirit in środa
    the dominicans in środa
    the archdiocese of poznań
    the church of St. Idzi in Środa
    the diocese of Poznań
    Opis:
    W XVIII wieku Środa Wielkopolska była znaczącym miasteczkiem w Wielkopolsce. Przynależała do archidiakonatu poznańskiego w diecezji poznańskiej i była siedzibą dekanatu. Kościół parafialny pw. Najświętszej Maryi Panny Wniebowziętej, wybudowany w XV wieku, posiadał rangę kolegiaty. Ponadto w mieście istniał konwent dominikanów, a na przedmieściach cztery niewielkie kościółki (oratoria). Akta wizytacji generalnej przeprowadzonej przez Franciszka Ksawerego Rydzyńskiego ukazują stan kolegiaty i innych świątyń w 1777 roku. Liczne ołtarze i dwie kaplice kolegiaty miały własne uposażenie, istniało kilka bractw, a duchowieństwo ze względu na istniejącą kapitułę i fundacje altaryjne było liczniejsze niż w wielu innych kościołach diecezji. Do artykułu został dołączony aneks, który zawiera akta wspomnianej wizytacji kościołów w Środzie w przekładzie na język polski.
    In the 18th century, Środa Wielkopolska was a significant town in Wielkopolska province. It belonged to the Archdiocese of Poznań in the diocese of Poznań and was the seat of the deanery. The parish church of the Blessed Virgin Mary Assumpted , built in the fifteenth century, possessed the rank of a collegiate church. In addition, there was a Dominican convent in the town, and four small churches (oratorios) in the suburbs. Acts of the general visitation carried out by Franciszek Ksawery Rydzyński show the state of the collegiate and other temples in 1777. Numerous altars and two collegiate chapels had their own payoff. There were several brotherhoods, and the clergy, due to the existing chapter and the altar foundations, were more numerous than in many other churches of the diocese. An annex was attached to the article, which contains the acts of the aforementioned church visits in Środa translated into Polish.
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2017, 12; 27-98
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Jan Joachim Tarło biskup kijowski (1718-1723) i poznański (1723-1732) Czynności pontyfikalne
    Jan Joachim Tarło Bishop of Kiev (1718-1723) and Poznań (1723-1732). Pontifical activities
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1039425.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    Bishop Jan Joachim Tarło
    Kiev diocese
    Cracow diocese
    Poznań diocese
    episcopal activities
    Poznań
    Warsaw
    Opis:
    Jan Joachim Tarło belonged to a family whose three members were bishops of Poznań in the first half of the 18th century. Jan Joachim was an alumnus of Jesuit schools and during his sojourn there joined the Society of Jesus which he left in 1689, passing into the ranks of diocesan clergy. In December 1718 he was granted papal provision to the bishopric in Kiev and remained in office until 1723 when he was transferred to the office of bishop of Poznań which he fulfilled for nine years until his death on 13 August 1732. He died in Vienna on his return from a journey to Rome.His book of pontifical activities for the years 1719-1731 survives till the present day and is stored at the Archdiocesan Archive in Poznań (catalogue number ASO 7). The book is divided into sections in which the following types of activities are recorded: ordinations of various degrees including presbiterate and episcopate, blessing of cornerstones, consecration and blessing of churches, consecration of permanent altars and portative stones, blessing of church bells, consecrations of the holy oils.From the records in the book it follows that during his ministry as bishop of Kiev, Tarło stayed in the Cracow diocese and discharged his duties there. Interestingly, there is no evidence of his performing any official acts in the area of the Kiev diocese, which must have been connected with the fact that already by then a great part of its territory (the bishopric of Kiev included) lay within the borders of the Russian Empire, whereas the part that remained in the Kingdom of Poland encompassed just a few parish churches.
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2016, 11; 109-152
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Poznańskie kościoły mendykantów w aktach wizytacji Józefa Rogalińskiego (1779-1781)
    Poznań Mendicant Churches in the Visitation Records of Józef Rogaliński (1779-1781)
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040135.pdf
    Data publikacji:
    2013-01-01
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    Poznań
    mendicant monasteries
    Józef Rogaliński as inspector
    inspector visits
    Opis:
    In the years 1779-1781 the Poznań deanery was inspected by Rogaliński, an ex-Jesuit, coadjutor of the archdeacon of Śrem. He also inspected the churches at the monasteries of the mendicant orders: the Dominicans, Carmelites of the Ancient Observance (two churches), the Minor Brothers Observants (known as Bernardines in Poland), Discalced Carmelites, Conventual Franciscans and Reformed Franciscans. Reports of the inspection visits contain information on the number of monks, the existence of a novitiate or a college in the convent and on the outlook of the churches. The visiting inspector paid special attention to such issues as indulgences, relics, brotherhoods, approval to administer the sacrament of penance and to preach sermons. What is particularly interesting is the religiosity of the faithful centered on the images and other objects of cult.
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2013, 8; 141-166
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Kapituła kolegiacka św. Mikołaja w Poznaniu na Zagórzu w latach 1728-1802. Struktura i skład personalny, posiedzenia, służba Boża
    The Chapter of St. Nicolas in Poznań at Zagórze in the Years 1728-1802. Structure and Personal Composition, Meetings, Divine Service
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040201.pdf
    Data publikacji:
    2012-01-01
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    chapter structure
    personal composition of the chapter
    chapter preposite
    canons
    chapter procurator
    general and partial chapters
    divine service of the chapter
    the collegiate chirch of St. Nicholas in Poznań
    the collegiate chapter of St. Nicholas in Poznań
    Zagórze in Poznań
    Opis:
    The beginnings of the chapter of the collegiate church of St. Nicholas at Zagórze in Poznań date back to 1476-1484. It existed until the first years of the 19th century. In the years 1728-1802 the chapter consisted of a preposite and eight canons: four participating in the income and four expecting. From 1736 one of the four participating members was the preposite of the chapter. In this period the chapter was headed by four successive preposites and twenty one new canons were admitted who came mostly from the milieu of the lower ranks of cathedral clergy and the professorial staff of the Lubrański academy. The chapter procurator who was in charge of its income was elected at the chapter general for a one-year term at the end of which he had to present an account for the income and the expenses. General meetings were held shortly after Michaelmas and with some exceptions were summoned every year. Partial chapters should be held monthly but in fact were called rather rarely, on average once a year. Divine service - the principal purpose of the existence of the chapter - was celebrated throughout that period but in an extent reduced proportionally to smaller rents. At chapter meetings attention was drawn to diligence, promptness and piety in celebrating Divine service; for a time absentees were even punished with lower wages. All obligations - officia, anniversaries, votives - were performed personally or through substitutes
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2012, 7; 47-81
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    O kościele szpitalnym św. Wawrzyńca w Poznaniu na Chwaliszewie u schyłku XVIII wieku
    The Hospital Church of St. Lawrence in the Poznań District of Chwaliszewo at the End of the 18th Century
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040355.pdf
    Data publikacji:
    2010-01-01
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    the church of st. lawrence in poznañ
    poznañ
    chwaliszewo
    poznañ archdiocese
    hospital church
    hospital for indigent priests
    hospital for the poor
    Opis:
    The hospital church of St. Lawrence in Chwaliszewo probably existed already at the beginning of the 16th century. It was administered by a provost whose salary was made up of rents and wages for running the hospital. The church was furnished with three altars, a pulpit, confessional and organ. The church was taken down in the second decade of the 19th century. There were two hospitals affiliated to the church: one for indigent priests (founded in 1652) and the other for indigent lay people. During the visitation of Rogaliński (1779) the former was not functioning whereas only six people were staying in the  latter.
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2010, 5; 67-82
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Starania arcybiskupa Marcina Dunina i Edwarda Raczyńskiego o przywrócenie klasztorów w archidiecezjach gnieźnieńskiej i poznańskiej
    The Efforts of Archbishop Marcin Dunin and Edward Raczyński to Restore Monasteries in the Gniezno and Poznań Archdioceses
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040524.pdf
    Data publikacji:
    2006
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2006, 2; 221-247
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dobrodzieje poznańskich karmelitów bosych w XVII i pierwszej połowie XVIII wieku w świetle kroniki klasztornej
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040605.pdf
    Data publikacji:
    2003
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2003, 1; 55-96
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wykaz personalny klasztorów diecezji poznańskiej z 1812 roku : rękopis OA II 40 w Archiwum Archidiecezjalnym w Poznaniu
    Das Personalverzcichnis der Kloster der Diözese Posen von 1812 nach dem Manuskript OA II 40 im Archidiözesanarchiv in Poznań
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040925.pdf
    Data publikacji:
    2020-04-27
    Wydawca:
    Katolicki Uniwersytet Lubelski Jana Pawła II
    Tematy:
    Kloster
    Großpolen
    19. Jahrhundert
    Katalog
    klasztor
    Wielkopolska
    XIX wiek
    katalog
    monastery
    Greater Poland
    19th century
    catalogue
    Opis:
    Mitte des 18. Jahrhunderts begann man mit der Herausgabe von Personalverzeichnissen der organisatorischen Einheiten der Diözesen bzw. Orden in den polnischen Gebieten. Diese unterschiedliche Bezeichnungen tragenden Verzeichnisse (Series, Elenchus, Schematismus, Katalog, Jahrbuch) wurden für den inneren Gebrauch der erwähnten kirchlichen Strukturen angefertigt. Seit dem letzten Viertel des 18. Jahrhunderts gibt es handschriftliche Verzeichnisse der Ordensniederlassungen zusammen mit ihrem Personalbestand, die auf Anordnung der Behörden der Teilungsmachte angefertigt wurden, welche die Existenz und Tätigkeit der Orden streng überwachten. Eine restriktive Politik gegen die Orden realisierten auch die Behörden des Großherzogtums Warschau, das in den Jahren 1807-1815 auf einem Teil des polnischen Territorien existierte. Nach dem Vorbild der gegen Ende des 18. Jahrhunderts von den preußischen Behörden eingeführten Praxis forderten sie von den Diözesanoberen, ihnen alljährlich ein Personalverzeichnis aller sich auf dem Territorien der betreffenden Diözese befindenden Kloster vorzulegen. Im Archidiozesanarchiv in Poznań befinden sich zwei identische Personalverzeichnisse aller in der Diözese Posen existierenden Kloster ( die Manuskripte mit den Signaturen OA 11 7 und OA II 40). Der Zeitpunkt ihrer Anfertigung ist mit Sicherheit auf das Jahr 1812 zu datieren. infolge detaillierter Untersuchungen konnte festgestellt werden, daß das Manuskript OA II 40 das ursprülingliche ist. Aus diesem Grunde wurde es der vorliegenden Publikation zugrundegelegt. Dieses Verzeichnis wurde für die Zivilbehörden des Großherzogtums Warschau angefertigt. Die Liste umfaßt 26 Männerloser (Benediktiner, Zisterzienser, Dominikaner, beschuhte Karmeliter, Bernhardiner, Franziskaner-Konventualen und Franziskaner-Reformaten) sowie 6 Frauenkloster (Benediktinerinnen, Zisterzienserinnen, Dominikanerinnen, barfüßige Karmelitinnen, Bernhardinerinnen, Franziskanerinnen-Klarissen). Für den Bedarf der vorliegenden Publikation des Manuskripts wurden die Angaben in drei Tabellen gegliedert: l. Verzeichnis der Klöster (Diözese, Ort, Departement, Kreis, Name des Ordens); 2. Verzeichnis der Ordensbrüder und Ordensschwestern (Name und Vorname, Alter, Zahl der verbrachten Jahre im Orden, im Kloster ausgeübte Funktionen, Ort, Departement und Kreis der Geburt); 3. Verzeichnis des klösterlichen Dienstpersonals (Name und Vorname, Herkunftsort, Art der ausgeübten Arbeit). Die im Verzeichnis enthaltenen Angaben ermöglichen eine Erweiterung des bisherigen Wissensstandes und können eine Grundlage für eingehendere Untersuchungen über die Orden in der Diözese Posen zu Beginn des 19. Jahrhunderts bilden.
    Źródło:
    Archiwa, Biblioteki i Muzea Kościelne; 2003, 79; 391-428
    0518-3766
    2545-3491
    Pojawia się w:
    Archiwa, Biblioteki i Muzea Kościelne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Diecezja poznańska u schyłku Rzeczypospolitej Obojga Narodów
    The Poznań Diocese at the Decline of the Polish-Lithuanian Commonwealth
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/607122.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    Poznań diocese
    Poznań bishop
    Andrew Stanislaus Kostka Młodziejowski
    Anthony Onuphrius Okęcki
    Poznań catedral
    Poznań chapter
    collegiate churches
    archdeaconships
    deaconships
    parishes
    religious orders
    diecezja poznańska
    biskup poznański
    Andrzej Stanisław Kostka Młodziejowski
    Antoni Onufry Okęcki
    katedra w Poznaniu
    kapituła poznańska
    kolegiaty
    archidiakonaty
    dekanaty
    parafie
    zakony
    Opis:
    In the investigated period of the years 1768–1793, the Poznań diocese belonged to the Gniezno metropolitan area and comprised the territory of more than 28 000 square kilometers, divided into two parts - Great Poland and Masovia. Poznań bishops resided mainly in Warsaw, in the Masovian part. The diocesan office in the years 1768–1780 was held by Andrew Stanislaus Młodziejowski and in the years 1780–1793 by Anthony Onuphrius Okęcki, both involved in state issues, includ- ing the post of crown chancellors. Pontifical duties were performer mainly by bishops suffragan, while the diocese was managed by general curates. The cathedral chapter in Poznań, constituted by 10 prelates and 23 canons, was the elite of the clergy. In addition to that, there were other bodies of clergy like curates, penitentiaries, two missionary colleges, rorantists and altarists. Collegiate chapters existed in three churches in Poznań, as well as in Warsaw, Środa Wielkopolska (Great Poland), Szamotuły and Czarnków. The area of the diocese was divided in to four archdeaconships - Poznań, Śrem, Pszczew and Warsaw - each divided into deaconships, amounting to the number of twenty nine. Within the territory of the diocese there were 466 parish churches and a significant number of churches and chapels of various character, with an abundance of priests. The clergymen derived mainly from the townspeople, and delegates of the bishop visiting the parishes positively assessed their moral conduct. In 1772 there were 78 male monasteries with 1549 monks and 17 female monasteries in the whole diocese.
    In the investigated period of the years 1768–1793, the Poznań diocese belonged to the Gniezno metropolitan area and comprised the territory of more than 28 000 square kilometers, divided into two parts - Great Poland and Masovia. Poznań bishops resided mainly in Warsaw, in the Masovian part. The diocesan office in the years 1768–1780 was held by Andrew Stanislaus Młodziejowski and in the years 1780–1793 by Anthony Onuphrius Okęcki, both involved in state issues, includ- ing the post of crown chancellors. Pontifical duties were performer mainly by bishops suffragan, while the diocese was managed by general curates. The cathedral chapter in Poznań, constituted by 10 prelates and 23 canons, was the elite of the clergy. In addition to that, there were other bodies of clergy like curates, penitentiaries, two missionary colleges, rorantists and altarists. Collegiate chapters existed in three churches in Poznań, as well as in Warsaw, Środa Wielkopolska (Great Po- land), Szamotuły and Czarnków. The area of the diocese was divided in to four archdeaconships - Poznań, Śrem, Pszczew and Warsaw - each divided into deaconships, amounting to the number of twenty nine. Within the territory of the diocese there were 466 parish churches and a significant number of churches and chapels of various character, with an abundance of priests. The clergymen derived mainly from the townspeople, and delegates of the bishop visiting the parishes positively assessed their moral conduct. In 1772 there were 78 male monasteries with 1549 monks and 17 female monasteries in the whole diocese.
    Źródło:
    Poznańskie Studia Teologiczne; 2018, 33; 163-175
    0209-3472
    Pojawia się w:
    Poznańskie Studia Teologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    O kościele i kapitule św. Mikołaja w Poznaniu na Zagórzu u schyłku XVIII wieku
    On the Church and Chapter of St. Nicholas in Poznań at Zagórze toward the End of the 18th Century
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040481.pdf
    Data publikacji:
    2009-01-01
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    zagórze in poznañ
    the collegiate of st. nicholas in poznañ
    the collegiate chapter of st. nicholas in poznañ
    Opis:
    The church of St. Nicholas most certainly existed already in the first half of the 12th century and was one of the oldest temples in Poznań. It was located at Zagórze, on the right bank of the Warta river, in close vicinity of the Poznań cathedral and the church of the Blessed Virgin Mary in Summo. In the second half of the 15th century it was raised to the status of collegiate and a chapter was created there made up of one praepositus and eight canons. In the 18th century the church had nine altars and four chapels, there was a parish school and a hospital for the poor. Due to massive damages and lack of means for repairs, at the beginning of the 19th century the church was closed and during the second Prussian occupation (most probably in 1817) it was taken down. Today there is no trace of it.
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2009, 4; 103-165
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Kroniki bernardynów poznańskich. Oprac. Salezy Bogumił Tomczak i Jacek Wiesiołowski. Poznań 2002, ss. XXIV i 456. Wydawnictwo Miejskie, seria: Kroniki Staropolskie
    Autorzy:
    Neumann, Piotr Franciszek
    Powiązania:
    https://bibliotekanauki.pl/articles/1040513.pdf
    Data publikacji:
    2006
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Źródło:
    Ecclesia. Studia z Dziejów Wielkopolski; 2006, 2; 367-371
    1731-0679
    Pojawia się w:
    Ecclesia. Studia z Dziejów Wielkopolski
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Structural basis of negative cooperativity in transthyretin
    Autorzy:
    Neumann, Piotr
    Cody, Vivian
    Wojtczak, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/1044029.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    negative cooperativity
    transthyretin
    Opis:
    A comparison of the AC and BD binding sites of transthyretin (TTR) was made in terms of the interatomic distances between the Cα atoms of equivalent amino acids, measured across the tetramer channel in each binding site. The comparison of the channel diameter for apo TTR from different sources revealed that in the unliganded transthyretin tetramers the distances between the A, D and H β-strands are consistently larger, while the distances between the G β-strands are smaller in one site than in the other. These differences might be described to have a 'wave' character. An analogous analysis performed for transthyretin complexes reveals that the shape of the plot is similar, although the amplitudes of the changes are smaller. The analysis leads us to a model of the changes in the binding sites caused by ligand binding. The sequence of events includes ligand binding in the first site, followed by a slight collapse of this site and concomitant opening of the second site, binding of the second molecule and collapse of the second site. The following opening of the first, already occupied site upon ligand binding in the second site is smaller because of the bridging interactions already formed by the first ligand. This explains the negative cooperativity (NC) effect observed for many ligands in transthyretin.
    Źródło:
    Acta Biochimica Polonica; 2001, 48, 4; 867-875
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Modeling studies of potato nucleoside triphosphate diphosphohydrolase NTPDase1: an insight into the catalytic mechanism
    Autorzy:
    Kozakiewicz, Anna
    Neumann, Piotr
    Banach, Mariusz
    Komoszyński, Michał
    Wojtczak, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/1040830.pdf
    Data publikacji:
    2008
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    potato apyrase
    NTPDase1
    enzymatic mechanism
    homology modeling
    Opis:
    Nucleoside triphosphate diphosphohydrolase - NTPDase1 (apyrase, EC 3.6.1.5) was modeled based on sequence homology. The single polypeptide chain of apyrase is folded into two domains. The putative catalytic site with the apyrase conserved regions (ACR 1-5) is located between these two domains. Modeling confirmed that apyrase belongs to the actin superfamily of proteins. The amino acids interacting with the nucleoside triphosphate substrate and probably involved in the catalyzed hydrolysis were identified. The proposed two-step catalytic mechanism of hydrolysis involves Thr127 and Thr55 as potential nucleophilic factors responsible for the cleavage of the Pγ and Pβ anhydride bonds, respectively. Their action seems to be assisted by Glu170 and Glu78 residues, respectively. The presence of two nucleophiles in the active site of apyrase explains the differences in the hydrolytic activity between apyrases and other enzymes belonging to the NTPDase family.
    Źródło:
    Acta Biochimica Polonica; 2008, 55, 1; 141-150
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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