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Wyszukujesz frazę "Nasir, Muhammad" wg kryterium: Autor


Wyświetlanie 1-14 z 14
Tytuł:
A Concept of V2G Battery Charging Station as the Implementation of IoT and Cyber Physical Network System
Autorzy:
Nasir, Muhammad
Safitri, Nelly
Rachmawati, Yassir
Arhami, Muhammad
Powiązania:
https://bibliotekanauki.pl/articles/27311964.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
IoT
cyber physical network
V2G
EV
SoC
charging station
Opis:
The integration of the internet of things (IoT) and cyber physical network into the battery charging station system is critical to the success and long-term viability of the vehicle to grid (V2G) trend for future automobiles in terms of environmental and energy sustainability. The goal of this article is to create a V2G battery charging station concept using the internet of things (IoT) and a cyber physical network system. The V2G charging station concept was developed with the idea that every charging electric vehicle (EV) can communicate and coordinate with the charging station's control center, which includes a cyber physical system that addresses privacy and security concerns. The communication protocol must also be considered by the charging station. The preliminary test has been taken into consideration. Normal hours (for case one), peak hours (for case two), and valley hours (for case three), respectively, were created as charging circumstances for EVs at charging stations. Simulations were run for each of the three case scenarios. Each EV's battery state of charge (SoC) is provided a 50 percent initial charge and user-defined SoC restrictions. The MATLAB/SIMULINK platform was used to run the case simulations. The grid frequency, charging station output power, and the EV's battery SoC were all observed during the 24- hour simulation. As a result, the developed V2G charging station concept can regulate its input and output power depending on the battery status of the EVs inside the charging station, as well as provide frequency regulation service to the grid while meeting the energy demand of EV customers.
Źródło:
International Journal of Electronics and Telecommunications; 2023, 69, 2; 269--273
2300-1933
Pojawia się w:
International Journal of Electronics and Telecommunications
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Heavy Metals in the Water, Sediment, and Fish Harvested from the Krueng Sabee River Aceh Province, Indonesia
Autorzy:
Nasir, Muhammad
Muchlisin, Zainal A.
Saiful, Saiful
Suhendrayatna, Suhendrayatna
Munira, Munira
Iqhrammullah, Muhammad
Powiązania:
https://bibliotekanauki.pl/articles/1955570.pdf
Data publikacji:
2021
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
water quality
sediment
gold mine
fish
heavy metals
Krueng Sabee
Opis:
The pollution of rivers from human activities such as housing, markets, workshops, transportation, land cultivation, and industry has become an issue. The increasing contribution of heavy metals to pollution in rivers has a direct effect on the metal bioaccumulation in fish. Therefore, this study aimed to examine the concentrations of Cd, Cu, and Pb in the waters, sediment, and fish harvested from the Krueng Sabee River, Aceh Province, Indonesia. Furthermore, the water, sediment, and fish samples were collected from six locations representing the upstream and downstream regions of the river. Cd, Cu, and Pb were analyzed using Atomic Absorption Spectrophotometry (AAS). The results showed that Cd, Cu, and Pb were not detected in the water, while the concentration of Cd in the sediments ranges between 0.0544 to 0.2683 mg kg-1, Cu ranges between 4.4149 to 14.8160 mg kg-1, and Pb ranges between 0.9186–15.4954 mg kg-1. Therefore, Cd, Cu, and Pb in the water and sediment were below the quality standard, but these heavy metals in the fish sample met the threshold limit. The highest Cd concentration was reported in Tor soro (5.5591 mg kg-1), and the highest concentration of Cu was reported in Mugil cephalus (6.7021 mg kg-1), while the higher Pb concentration was reported in Cyclocheilichthys Apogon (0.0279 mg kg-1).
Źródło:
Journal of Ecological Engineering; 2021, 22, 9; 224-231
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and activity evaluation of Ce-Mn-Cu mixed oxide catalyst for selective oxidation of co in automobile engine exhaust: effect of Ce/Mn loading content on catalytic activity
Autorzy:
Bilal, Yasir
Nasir, Muhammad Ali
Nasreen, Sadia
Akhter, Niaz Ahmed
Pasha, Riffat Asim
Noor, Muhammad Farhan
Powiązania:
https://bibliotekanauki.pl/articles/101992.pdf
Data publikacji:
2018
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
base metal oxide catalyst
catalytic converter
CO sensor
CO-precipitation
catalytic activity
katalizator tlenku metalu zasadowego
katalizator
czujnik CO
strącanie CO
aktywność katalityczna
Opis:
A series of Mn-doped CeO2-CuO catalyst (CeO2-MnOx-CuO) (Ce/Mn molar ratio of 0.5, 1.0 2.0 and 3.0) were prepared using co-precipitation method for the selective oxidation of CO in automobile engine exhaust. The content of copper was 5.0 wt. % in each sample. Catalysts were installed on the automobile engine exhaust and CO amount was recorded with help of CO sensor, with and without the catalyst. The catalytic converter efficiency was estimated for each catalyst through efficiency formula. It was observed that Ce/Mn catalyst with a molar ratio of 2.0 shows the maximum efficiency (88.35%). Stability of conversion process was analyzed by plotting the CO amount with respect to time. The catalyst with Ce/Mn molar ratio of 2.0 performed the most streamline conversion process with least deviations.
Źródło:
Advances in Science and Technology. Research Journal; 2018, 12, 1; 260-266
2299-8624
Pojawia się w:
Advances in Science and Technology. Research Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Deep Neural Network for Supervised Single-Channel Speech Enhancement
Autorzy:
Saleem, Nasir
Irfan Khattak, Muhammad
Ali, Muhammad Yousaf
Shafi, Muhammad
Powiązania:
https://bibliotekanauki.pl/articles/177497.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
deep neural network
intelligibility
speech enhancement
speech quality
supervised learning
Wiener filtering
Opis:
Speech enhancement is fundamental for various real time speech applications and it is a challenging task in the case of a single channel because practically only one data channel is available. We have proposed a supervised single channel speech enhancement algorithm in this paper based on a deep neural network (DNN) and less aggressive Wiener filtering as additional DNN layer. During the training stage the network learns and predicts the magnitude spectrums of the clean and noise signals from input noisy speech acoustic features. Relative spectral transform-perceptual linear prediction (RASTA-PLP) is used in the proposed method to extract the acoustic features at the frame level. Autoregressive moving average (ARMA) filter is applied to smooth the temporal curves of extracted features. The trained network predicts the coefficients to construct a ratio mask based on mean square error (MSE) objective cost function. The less aggressive Wiener filter is placed as an additional layer on the top of a DNN to produce an enhanced magnitude spectrum. Finally, the noisy speech phase is used to reconstruct the enhanced speech. The experimental results demonstrate that the proposed DNN framework with less aggressive Wiener filtering outperforms the competing speech enhancement methods in terms of the speech quality and intelligibility.
Źródło:
Archives of Acoustics; 2019, 44, 1; 3-12
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Solublising Aids on The Entrapment of Loratidine in Pre-Fabricated PVA Filaments Used for FDM Based 3D-Printing
Autorzy:
Mahmood, Faisal
Hussain, Amjad
Arshad, Muhammad Sohail
Abbas, Nasir
Irfan, Muhammad
Qamar, Nadia
Hussain, Fahad
Ghori, Muhammad Usman
Powiązania:
https://bibliotekanauki.pl/articles/895332.pdf
Data publikacji:
2020-02-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
3D printing
Plasticizers
Fused deposition modelling (FDM)
PVA filaments
Solubilizers
Opis:
Low drug loading efficiency is the limiting factor in the use of pre-fabricated filaments for 3D printing of pharmaceuticals. The aim of present study was to modify the material properties of pre-fabricated filament by incorporating the suitable solubilizing aids in order to enhance the drug loading efficiency. Loratadine was loaded into PVA filaments by using solubilizers (Soluplus®, Sodium lauryl sulphate) and plasticizers (glycerin and Polyethylene glycol-400) and the printability of filaments was investigated. The treated filaments were characterized for morphology and diameter changes, drug content, FTIR and thermal properties and printed into tablets of suitable dimensions. The printed tablets were also characterized for drug assay and drug release. The results have shown that the surface of different drug loaded filaments become rough with almost no change in diameter hence, these filaments remained printable. However, there was 7 to 24 times enhancement in drug content of filaments treated with particularly those pretreated with glycerin and soaked in drug solution containing Soluplus. The printed tablets have also shown almost similar drug content as their precursor filaments and the release followed diffusion mechanism in most of the formulations. The study concludes that the treatment of PVA filament with solubilizer aids has significantly improved the drug loading entrapment without compromising the printability.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 1; 175-182
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Kinetic Study of Adsorption of Metal Ions (Iron and Manganese) in Groundwater Using Calcium Carbide Waste
Autorzy:
Karim, Muhammad Arief
Nasir, Subriyer
Widowati, Tri Wardani
Hasanudin, Udin
Powiązania:
https://bibliotekanauki.pl/articles/24201681.pdf
Data publikacji:
2023
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
calcium carbide residual
iron
manganese
groundwater
Opis:
Calcium carbide waste (CCW), the rest of the carbide welding workshop industry, is available in quite a lot and is immediately disposed of into the environment. Because CWW has a high pH value and a large specific surface area, it can act as an adsorbent in removing metals from groundwater. The content of metals in groundwater is indicated by a reddish color; however, upon contact with air, groundwater oxidation causes iron ions and manganese ions to precipitate. Synthetic groundwater was prepared in this experiment using reagents containing and . Observations were made in a batch process to assess the potential and ability of CCW to reduce iron and manganese levels in groundwater. In this study, to achieve equilibrium, CCW was mixed with 100 mL of synthetic solution and shaken at 25°C with a shaker. Operating time, levels of Fe(II) and (Mn(II) metals, and the mass of CCW were some of the parameters studied in this study. CCW was very good at reducing levels of iron ions and manganese ions after 60 minutes of operation. The percentage of removal of iron and manganese ions respectively – successively increased from 93.765 to 97.99% for iron ions and manganese ions from 91.83 to 95.14% for the initial concentration range of 40 mg/L, 60 mg/L, 80 mg/L, and 100 mg/L. Furthermore, the adsorption kinetics of CCW adsorbent in a mixture of iron ion and manganese ion solutions is a second-order kinetic equation. This confirms that the adsorption of CCW on iron ions and manganese ions is a chemisorption process. Calcium carbide waste has the potential to act as an absorbent of heavy metals in groundwater, especially iron and manganese ions.
Źródło:
Journal of Ecological Engineering; 2023, 24, 5; 155--165
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A New Prototype Design and Experimental Study for Assessing Spontaneous Coal Combustion
Autorzy:
Aryansyah, -
Ibrahim, Eddy
Nasir, Subriyer
Said, Muhammad
Kurniawan, Ian
Huda, Adri
Powiązania:
https://bibliotekanauki.pl/articles/952386.pdf
Data publikacji:
2019
Wydawca:
Polskie Towarzystwo Inżynierii Ekologicznej
Tematy:
coal
spontaneous combustion
energy management
environmental technology
oxidation
Opis:
This present study contribute to provide a simple technology to early detect the phenomenon of spontaneous coal combustion. A new prototype is designated to detect the CO gas formation as a product of initial coal oxidation. Moreover, several parameters including coal quality, coal weight sample, ambient temperature, and air flow were employed to investigate the effects of each parameter to the CO formation time. The results show that the coal characterisation have a significant effect in the CO formation time where the coal having a higher fixed carbon and high grass calorific values provide the high liability of spontaneous coal combustion. However, these finding only occurred in low weight sample where in the high coal weight sample only fixed carbon plays the main role in determining the CO formation time. Furthermore, the prototype ambient temperature become the important parameter in the boosting of CO formation time where airflow only enhance the CO formation time in low temperature condition (below 29°C). Moreover, these findings opens a new sight in coal management, especially in Indonesia, where controlling the coal and atmosphere temperature could effectively prevent the spontaneous coal combustion especially in coal stockpile. Nevertheless, the other factor including airflow and coal weight sample also need perfect controlling because all of these factors potentially create a perfect environment to combust the coal spontaneously.
Źródło:
Journal of Ecological Engineering; 2019, 20, 6; 9-17
2299-8993
Pojawia się w:
Journal of Ecological Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
FORMULATION AND EVALUATION OF INDOMETHACIN LOADED NANOSPONGES FOR ORAL DELIVERY
Autorzy:
Abbas, Nasir
Sarwar, Komal
Irfan, Muhammad
Hussain, Amjad
Mehmood, Rabia
Arshad, Muhammad S.
Shah, Pervaiz A.
Powiązania:
https://bibliotekanauki.pl/articles/895238.pdf
Data publikacji:
2018-10-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
sustained release
indomethacin
Nanosponges
Emulsion solvent diffusion method
Franz diffusion cell
Opis:
Nanosponges (NS) loaded sustained release tablet formulations of a non-steroidal anti-inflammatory drug; Indomethacin were successfully developed and evaluated for their pharmaceutical properties. Twelve nanosponge formulations were fabricated by solvent diffusion method by using different ratios of drug and polymers (ethyl cellulose and polyvinyl alcohol). Particle size of all the formulations was in the nano range of 221 to 625 nm and it was found dependent on the polymer concentration. Drug loading and entrapment efficiency was ranged in 32.2 to 59.4 % and 30.1 to 64.8 %, respectively. Formulations with equal proportion of drug and polymer resulted in higher values of drug loading and entrapment efficiency. Percent yield was also found dependent on the relative drug polymer ratio with highest value of 51 % was achieved for the formulation having same drug to polymer ratio. SEM results confirmed the formation of spherical and porous structures. Structural analysis by Fourier transform infrared spectroscopy (FTIR), powder x-ray diffraction (PXRD) showed the absence of any interaction between drug and polymer. In comparison to pure drug, NS formulations showed a linear intrinsic dissolution rate (IDR) profile depicting a controlled release profile. Diffusion studies of NS formulations performed by Franz diffusion cell and dialysis bag methods showed comparable results in terms of precision and linearity of diffusion profile. Tablets prepared from the drug loaded NS showed acceptable values for hardness, friability and drug content. Release of drug from NS tablets was confirmed as sustained release behaviour.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 5; 1201-1213
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A suspicious non-healing wound of the pinna
Podejrzana, niegojąca się rana małżowiny usznej
Autorzy:
Nasir, Mohd Shaiful Nizam Mamat
Yusof, Suhaimi
Bakar, Muhammad Nasri Abu
Mohamad, Irfan
Powiązania:
https://bibliotekanauki.pl/articles/1034786.pdf
Data publikacji:
2018
Wydawca:
Medical Communications
Tematy:
pinna
squamous cell carcinoma
wound
Opis:
Squamous cell carcinoma of the pinna occurs primarily in older males who are exposed to sunlight for a prolonged period. Most squamous cell carcinomas of the pinna are well differentiated and present as a painless mass or a sessile nodule. We describe an interesting case of an adult woman with a non-healing wound located on the right pinna which was treated conservatively, and was later diagnosed as squamous cell carcinoma.
Rak kolczystokomórkowy skóry zlokalizowany w obrębie małżowiny usznej występuje głównie u mężczyzn w starszym wieku, którzy są narażeni na długotrwałe działanie promieni słonecznych. W większości przypadków nowotwór ten jest dobrze zróżnicowany i ma postać niebolesnej masy lub nieuszypułowanego guzka. W pracy opisujemy ciekawy przypadek dorosłej kobiety z niegojącą się raną prawej małżowiny usznej – pacjentkę leczono zachowawczo, zanim ustalono rozpoznanie raka kolczystokomórkowego.
Źródło:
Pediatria i Medycyna Rodzinna; 2018, 14, 4; 425-427
1734-1531
2451-0742
Pojawia się w:
Pediatria i Medycyna Rodzinna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Seroprevalence of Toxoplasmosis among Human Immunodeficiency Virus infected pregnant women in Abuja Teaching Hospital, Nigeria
Autorzy:
Zakari, Maryam Muhammad
Yabagi Isah, Aliyu
Offiong, Richards
Yunusa, Thairu
Abdullahi, Idris Nasir
Powiązania:
https://bibliotekanauki.pl/articles/2038266.pdf
Data publikacji:
2020-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
HIV coinfections
Nigeria
pregnant women
toxoplasmosis
Opis:
Introduction. Toxoplasmosis is a neglected parasitic infection that has economic and epidemiological significance. Data on toxoplasmosis seroprevalence among Human Immunodeficiency Virus (HIV) infected pregnant women may be of obstetric and neonatal concern. Aim. The study was designed to determine the seroprevalence of Toxoplasmosis and associated risk factors in HIV-positive pregnant women attending the University of Abuja Teaching Hospital, Abuja, Northcentral Nigeria. Material and methods. This was a hospital-based cross-sectional study. A total of 160 HIV seropositive pregnant women were recruited. Blood samples were collected and tested for anti-T. gondii IgM and IgG using Enzyme Linked Immunosorbent Assay (ELISA). Structured questionnaires were used to collate the sociodemographic variables of participants. Results. Out of the 160 of HIV seropositive pregnant women, the seroprevalence anti-T. gondii IgG and IgM were 29.4% and 4.4%, respectively. There was no significant association between anti-T. gondii and all sociodemographic variables studied (p>0.05). Conclusion. The overall result of this study revealed that the majority of pregnant women were exposed to toxoplasmosis much earlier in life. Hence, these findings will assist obstetricians and gynecologists in the early diagnosis and management of Toxoplasma gondii infection in pregnant women, especially HIV coinfected ones with IgM seropositivity.
Źródło:
European Journal of Clinical and Experimental Medicine; 2020, 3; 170-175
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Image encryption based on Chebyshev chaotic map and S8 S-boxes
Autorzy:
Hussain, Iqtadar
Anees, Amir
Alkhaldi, Ali Hussain
Aslam, Muhammad
Siddiqui, Nasir
Ahmed, Rehan
Powiązania:
https://bibliotekanauki.pl/articles/173918.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
image encryption
chaos
noise-resistant
statistical analysis
key sensitivity
Opis:
The encryption of image data is artful as compare to others due to some special characteristics such as entropy, contrast, the correlation between the pixels, intensity, and homogeneity. During encryption process, it is conventionally not easy to manage these characteristics with non-chaotic cryptosystems. Therefore for the sake of strong encryption algorithms, in last decades many cryptographers have presented invulnerable schemes for image encryption based on the chaotic maps. This manuscript aims to propose a strong encryption scheme based on a symmetric group of permutation advanced encryption standard (AES) substitution boxes and modified Chebyshev map. Principally, the secret key depends upon the parameters of Chebyshev map to create confusion in the main image and is encrypted by the scheme made from the S8 AES S-boxes and chaotic map. By this procedure, one can obtain an encrypted image that is entirely twisted. The results of analyses showed that the presented image encryption is strong and invulnerable.
Źródło:
Optica Applicata; 2019, 49, 2; 317-330
0078-5466
1899-7015
Pojawia się w:
Optica Applicata
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
System efficiency for AC vs. DC distribution paradigms: a comparative evaluation
Autorzy:
Gelani, Hasan Erteza
Khan, Sidra
Dastgeer, Faizan
Idrees, Zeba
Afzal, Muhammad Waqas
Nasir, Mashood
Powiązania:
https://bibliotekanauki.pl/articles/2173534.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
AC vs DC
DC distribution
efficiency analysis
residential loads
AC/DC
dystrybucja prądu stałego
analiza wydajności
obciążenie mieszkalne
Opis:
The birth of electricity witnessed “the battle of currents” between AC and DC as a medium of power transfer. AC won the battle in the first place because of its ability to transform voltage levels. However, with the development of power electronic converters (PECs), DC is striking back. Most of the electronic loads in our conventional AC-based homes are DC by nature. Moreover, the modern concept of energy-efficient variable speed drive (VSD) based loads, i.e. DC-inverter based air-conditioners and refrigerators, require a DC link for their operation. The driving component of all such loads is the PEC. The operational efficiency of PECs depends on the loading which varies throughout the day. This paper presents a mathematical model based on a bottom-up approach to the comparative efficiency analysis of AC and DC distribution systems considering daily load variation. Two topologies are presented where AC and DC distribution systems are compared in terms of efficiency. The first topology (T1) defines a separate/independent converter for each load, whereas in the second topology (T2) loads of a particular class are lumped and driven by a single converter. The results present DC distribution better than AC distribution with an efficiency advantage of 2.28% and 1.57% for T1 and T2, respectively.
Źródło:
Bulletin of the Polish Academy of Sciences. Technical Sciences; 2022, 70, 1; e139956, 1--9
0239-7528
Pojawia się w:
Bulletin of the Polish Academy of Sciences. Technical Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of neutrophil phagocytic, complement functions, and cytokines expression among diabetic patients in Abuja, Nigeria
Autorzy:
Babandina, Musa Muhammad
Mainasara, Abdullahi Suleiman
Bakare, Mustapha
Emeribe, Anthony Uchenna
Shuwa, Halima Ali
Haruna, Shamsuddeen
Muhammad, Aminu Said
Abdullahi, Idris Nasir
Powiązania:
https://bibliotekanauki.pl/articles/454973.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
diabetes mellitus
effector molecules
pro-inflammatory markers
Opis:
Introduction. Inflammatory response in Diabetes Mellitus (DM) begins with chronic sub-clinical inflammations as a result of insulin resistance and activation of both innate and adaptive immune system as the disease progresses to complicated diabetes. Hence, the present study investigated the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among diabetic and non-diabetic patients attending the National Hospital in Abuja, Nigeria. Aim. To evaluate the neutrophil phagocytic, complement function (CH50), and some cytokine profiles among post-operative septic diabetic and post-operative septic non-diabetic patients at the National Hospital in Abuja, Nigeria. Material and methods. Subjects were recruited by convenient sampling technique through interviewer-administered questionnaires. Subsequently, blood samples were collected. Fasting blood sugar (FBS) (mmol/L) was determined using glucose oxidase method. Neutrophil function test (Fmol/phag) was assayed using nitroblue tetrazolium reduction test (NBT). Hemolytic complement function (CH 50) test was conducted using serum harvested from sheep sensitized with human group (ORh D +ve) red blood cells. While serum Interleukin-4, -6, -10 and TNF- α were determined using Enzyme Linked Immunosorbent Assay (ELISA). Results. Mean ± Standard deviation (SD) of FBS concentration of 10.5 ± 1.3 (mmol/|L) among diabetic and 4.7 ± 0.9 (mmol/L) among non-diabetics was recorded. There is a decrease in neutrophil phagocytic function with a mean ± SD of 5.4 ± 2.1 (Fmol/ phag) in diabetics compared to 9.2 ± 2.1 (Fmol/phag) in non-diabetics. Similarly, complement (CH 50) function and C-reactive protein were significantly lower in diabetics when compared to non-diabetics (p<0.001). There was a significant difference in IL-6 concentration between diabetics and non-diabetics groups, but no significant difference was observed in TNF-α, IL-4 and IL-10 concentrations between study groups (p>0.05). TNF-α and IL-6 was significantly higher in diabetics with cardiovascular disorders compared to non-diabetics subjects with cardiovascular disorders (p<0.001). Conclusion. Findings from this study revealed the association of complement, neutrophil phagocytic function, CRP and IL-6 among septic diabetic patients,. In addition TNF-α and IL-6 expression was higher in DM patients with cardiovascular disorders.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 3; 229-235
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Selective arylation of phenol proteted propygyl bromide via pd-catalysed Suzuki coupling reaction: synthesis, mechanistic studies by DFT calculations and Their Pharmacological Aspects
Autorzy:
farooq, hira
rasool, nasir
Ansari, Muhammad T.
rizwan, komal
mahmood, tariq
israr, hira
Ayub, Khurshid
rasheed, tahir
Zareen, Seema
Akhtar, muhammad N.
iqbal, sarosh
Powiązania:
https://bibliotekanauki.pl/articles/895304.pdf
Data publikacji:
2018-08-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
biofilm
phenol
DFT
Suzuki coupling
organoboron
Biaryl
Opis:
Biaryls are the potential source of synthetic drugs. The present study describes the synthesis of a series of functionalized biphenyl derivatives (3a-3g) using Pd-catalyzed Suzuki coupling reaction. The experimental results revealed the facile synthesis of biphenyl derivatives (3a-3g) with notably high yield (80-88 %). Density functional theory (DFT) studies were performed by Gaussian 09 software in order to rationalize the selectivity of coupling at C-Br bond instead of C-Cl bond. In addition of synthesis, the biological activities (biofilm inhibition, hemolytic and anti-thrombolytic) of these novel compounds were investigated. These results exhibited good biofilm inhibition (5.86-65.8 %), hemolytic (1.32-30.1 %) and anti-thrombolytic activities (9.64-42.5 %), indicating the potential use of these compounds for pharmaceutical applications.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 911-919
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
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