Autor: Nan, Zhao - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Fabrication of a high wear resistance AA7075/AL2O3 composites via liquid metallurgy process
Autorzy:: Sivaraman, R.
Jalil, Abduladheem Turki
Aravindhan, Surendar
Nan, Zhao
Vini, M. Heydari
Daneshmand, S.
Powiązania:: https://bibliotekanauki.pl/articles/27312401.pdf
Data publikacji:: 2022
Wydawca:: Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:: zużycie
kompozyty
odlewanie
AA7075
Al2O3
wear
composites
stir casting
Opis:: In the present study, AA7075/Al2O3 composites have been fabricated via liquid metallurgy process. AA7075 alloy and Al2O3 particles were taken as the base matrix and reinforcements, respectively. Then, contents of 3 and 6 wt. % of Al2O3 subdivisions were added into the AA7075 matrix. To improve wettability and distribution, reinforcement particles were pre-heated to a temperature of 550°C for each composite sample. A hardened EN32 steel disc as the counter face was used to evaluate the wear rate pin-on-disc. The results showed that the wear rate of the AA/Al2O3 composites was smaller than that of the monolithic AA7075 samples. Finally, the worn surfaces of samples were investigated by SEM.
Źródło:: International Journal of Applied Mechanics and Engineering; 2022, 27, 4; 205--210
1734-4492
2353-9003
Pojawia się w:: International Journal of Applied Mechanics and Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Polymorphisms in the p53 pathway genes and micronucleus occurrence in Chinese vinyl chloride-exposed workers
Autorzy:: Li, Yong
Feng, Nan-Nan
Zhang, Guang-Hui
Wang, Qi
Hao, Yan-Hui
Nanzhang, Ya
Long, Changxu
Li, Yongliang
Brandt-Rauf, Paul W.
Xia, Zhao-Lin
Powiązania:: https://bibliotekanauki.pl/articles/2179059.pdf
Data publikacji:: 2013-12-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: VC
occupational exposure
p53 pathway genes
genetic polymorphism
Opis:: Objectives: To investigate the association between polymorphisms in the p53 pathway genes and chromosomal damage in vinyl chloride (VC)-exposed workers. Materials and Methods: Cytokinesis block micronucleus test was performed in 310 VC-exposed workers and 149 non-exposed workers to determine chromosomal damage. The polymerase chain reaction and restriction fragment length polymorphism technique were used to detect six SNPs in the p53 pathway genes involved in the cell cycle. Results: There was a highly significant dose-response relationship between VC exposure and chromosomal damage. Individuals carrying the variant genotypes were at higher risk for chromosomal damage compared with their wild type genotype: p53rs1042522, MDM2 Del1518rs3730485, MDM2rs2279744 and GADD45Ars532446. On the other hand, individuals possessing the variant genotype of CDKN2A rs3088440 had significantly decreased risk compared with the corresponding wild-type. Conclusions: Genetic polymorphisms in P53 pathway genes may have an impact on VC-induced chromosomal damage.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2013, 26, 6; 825-836
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Dexamethasone inhibits U937 cell adhesion via the down-regulation of ROCK1 activity
Autorzy:: Liu, Dong
Chen, Xing
Xiong, Ren
Ning, Ya
Li, Ping
Peng, Yan
Liu, Ping
Zhao, Yan
Yang, Nan
Zhou, Yuan
Powiązania:: https://bibliotekanauki.pl/articles/1039650.pdf
Data publikacji:: 2012
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: dexamethasone
ROCK1
fasudil
non-genomic effects
Opis:: Objective. To explore the effect of dexamethasone (DEX) on monocyte adhesion function and its underlying mechanism. Methods. The effects of DEX and fasudil on adhesion of cultured U937 monocytes to human umbilical vein endothelial cells (HUVEC) following stimulation with phorbol myristate acetate (PMA) were studied; Changes in the Rho-associated coiled-coil protein kinase 1 (ROCK1) protein content and activity were evaluated. Results. DEX and fasudil significantly inhibited U937 cell adhesion rates under PMA stimulation and inhibited ROCK1 activity. Mifepristone (RU-486) and cycloheximide (CHX) did not alter these effects of DEX. Conclusions. DEX interferes with the adhesion function of U937 cells through the inhibition of ROCK1 activity.
Źródło:: Acta Biochimica Polonica; 2012, 59, 4; 557-560
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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