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    Wyświetlanie 1-4 z 4
    Tytuł:
    A brief review of fluconazole as an antifungal agent and the need for research into its nanoformulation
    Autorzy:
    Nagaraj, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/2201067.pdf
    Data publikacji:
    2022
    Wydawca:
    Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
    Tematy:
    fluconazole
    antibiotic
    structure
    toxicity
    nanoformulations
    flukonazol
    antybiotyk
    struktura
    toksyczność
    nanopreparaty
    Opis:
    Purpose Antifungals compounds have gained significant attention, and in this context, fluconazole as an antifungal is used predominantly, and the use of a nanoformulated form of this is discussed. Design/methodology/approach Fluconazole, an FDA-approved antibiotic, is an effective antimicrobial especially used to treat fungal infections. Its uniqueness lies in the fact that it contains fluoride with triazole functionality. Its efficacy against various types of fungus is demonstrated. Findings Although it is one of the effective antibiotics, its side effects are well documented, and due to this, many techniques are tried to improve its efficacy with lesser side effects. Research limitations/implications In this respect, nanoparticles play a crucial role, and many studies worldwide are carried out on this aspect. Among many nano techniques use of chitosan as well as lipid carriers of fluconazole are being considered. However, systematic studies are warranted to take this aspect into clinical trials. Practical implications Nano-based platforms seem to be an alternating hope to combat resistance and side effect. Originality/value A thorough study is the need of the hour to devise a proper nano-based strategy of fluconazole.
    Źródło:
    Journal of Achievements in Materials and Manufacturing Engineering; 2022, 114, 2; 81--85
    1734-8412
    Pojawia się w:
    Journal of Achievements in Materials and Manufacturing Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preparation and characterization of nano magnetic fluid for automotive applications
    Autorzy:
    Thanikachalam, J.
    Nagaraj, P.
    Karthikeyan, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/379453.pdf
    Data publikacji:
    2019
    Wydawca:
    Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
    Tematy:
    nano magnetic fluid
    yield stress
    nickel nanoparticles
    viscosity
    sedimentation
    Rate
    płyn nano magnetyczny
    granica plastyczności
    nanocząstki niklu
    lepkość
    szybkość sedymentacji
    Opis:
    Purpose: of this paper is to prepare a nano magnetic fluids with nano additives to have the combined characteristics of high yield stress and better magnetic properties for smart vehicles. This study focuses on increasing the sedimentation time of the fluid using suitable nano additive nickel along with graphene as fillers. Design/methodology/approach: Magnetic nano sized nickel particle based electromagneto-rheological fluid was prepared and graphene nanoparticle with thickness less than 10nm was introduced as an additive to reduce its sedimentation. This added plate like graphene acts as filler which seals the interfaces of nickel particles and thereby it improves the resistance to sedimentation. Triton X 100 was added as the surfactant for the fluid to reduce the agglomeration of the particles. Findings: Morphology of pure nickel and graphene were examined using scanning electron microscopy (SEM) images. Research limitations/implications: The important limitations is that freely dispersed micron sized iron particles could settle over a period of time, in the form of cakes at the bottommost, and it is tedious to recuperate as dispersed phase. In this investigation, nano sized nickel particles were used as additive to reduce the sedimentation of micron sized iron particles so that, the mixture is homogeneous for extended period of time. In future, addition of different types composite additives in the magnetorheological fluid could be made for the better sedimentation control. Practical implications: The sedimentation problem is one of the major drawback in the smart fluids, which can be eliminated by adding nano particles. For conventional fluid, the complete sedimentation will occur in 2 hours while the improved nano magnetic fluid with additive has good resistance to settle the micron sized iron particle up to 10 hours. Originality/value: To prepare a low cost magnetorheological fluid with nano additives like nickel particles along with fillers as graphene nano particles. With this addition of nickel and inclusion of graphene, the sedimentation problem in magnetorheological fluids is significantly reduced. This magnetorheological fluids can be used in brakes and dampers of automobiles.
    Źródło:
    Archives of Materials Science and Engineering; 2019, 96, 2; 49-55
    1897-2764
    Pojawia się w:
    Archives of Materials Science and Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Computational and experimental study on oxygen enriched intake of a spark ignition engine
    Obliczeniowe i eksperymentalne badania wzbogacania tlenem na wlocie silnika z zapłonem iskrowym
    Autorzy:
    Sakleshpur Nagaraja, S.
    Nagaraj, Ch.
    GN, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/357354.pdf
    Data publikacji:
    2015
    Wydawca:
    Politechnika Śląska
    Tematy:
    wzbogacenie tlenem
    silnik z zapłonem iskrowym
    parametry
    oxygen enriched intake
    SI engine
    emission parameters
    Opis:
    Obliczeniowe i eksperymentalne badania przeprowadzono na silniku z zapłonem iskrowym (SI) wzbogaconym przy wlocie w tlen. Badanie miało na celu walidację funkcji Wiebe, która służy do poboru tlenu. Obliczenia przeprowadzono w warunkach pełnego obciążenia na czterech prędkościach obrotowych (2500, 3000, 3500 i 4000 rpm) dla różnych mieszanek benzynywzbogaconej w tlen (4%, 8% i 12% w stosunku do masy tlenu) w AVL Boost, oprogramowaniu, które analizuje jeden wymiar silnika. Obliczeniowe i doświadczalne wyniki uzupełniają się wzajemnie i sprawdzają wykorzystanie AVL Boost, przy poborze tlenu do silnika. Emisja HC i CO spadła drastycznie wraz ze wzrostem stężenia tlenu. Nie zauważono jednak nagłej zmiany stężenia emisji NOx.
    A numerical and experimental study was carried out on oxygen enriched intake in an spark ignited (SI) engine. The study aims at validation of Wiebe function for oxygen enriched intake. This computational study was carried out at full load conditions at four engine speeds (2500, 3000, 3500 and 4000 rpm) for different blends of oxygen enriched gasoline (4%, 8% and 12% by mass of oxygen) in AVL BOOST, a one dimension engine analysis software. The computational and experimental results complement each other validating the use of AVL Boost for oxygen enriched intake. HC and CO emissions decreased drastically with increasing concentration of oxygen. However, there was abrupt increase in concentration of NOx emissions.
    Źródło:
    Archiwum Gospodarki Odpadami i Ochrony Środowiska; 2015, 17, 3; 27-40
    1733-4381
    Pojawia się w:
    Archiwum Gospodarki Odpadami i Ochrony Środowiska
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The prevalence, characteristics, and impact of work-related musculoskeletal disorders among physical therapists in the Kingdom of Saudi Arabia – a cross-sectional study
    Autorzy:
    Kakaraparthi, Venkata Nagaraj
    Vishwanathan, Karthik
    Gadhavi, Bhavana
    Reddy, Ravi Shankar
    Samuel, Paul S.
    Alshahrani, Mastour Saeed
    Kakaraparthi, Lalitha
    Gannamaneni, Vamsi Krishna
    Tedla, Jaya Shanker
    Powiązania:
    https://bibliotekanauki.pl/articles/2081895.pdf
    Data publikacji:
    2021-08-31
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    physical therapy
    ergonomics
    musculoskeletal disorders
    workload
    prevalence
    Saudi Arabia
    Opis:
    BackgroundPhysical therapists are known to be susceptible to work-related musculoskeletal disorders (WMSDs), but the prevalence of WMSDs in Saudi Arabia has not been documented. This study aimed to establish the prevalence, characteristics, and risk factors of WMSDs among physical therapists in Saudi Arabia.Material and MethodsA cross-sectional study was conducted among 113 physical therapists in Saudi Arabia using a 6-component questionnaire. Descriptive statistics, incidence, percentages, and χ2 test were used for data analysis.ResultsThe response rate was 68.8%. The reported 12-month incidence of WMSDs was 83.8%. The low back (63.7%) was the most common site of these disorders, followed by the neck (59.2%), while the hip/thigh (4.4%) was the least involved body part. Incidence was related to gender: females were more affected than males (neck, shoulders, low back); age: younger therapists were more affected than older ones (shoulders, low back); working sector: government sector workers were more affected than those employed in other sectors (neck); and specialty: orthopedic specialists were the most frequently affected, followed by those specializing in neurology (thumbs, upper back, knees, ankle/foot). Most of the physical therapists had >5 periods of neck, shoulder, and low-back WMSDs. The most important risk factor for WMSDs was treating more patients in a day (47.7%). The most frequently adopted handling strategy identified to combat WMSDS was modifying the patient’s position (62.8%).ConclusionsOverall, WMSDs among physical therapists in Saudi Arabia are common, with the low back and the neck constituting the most frequently affected body regions. Professional experience and the awareness of ergonomics principles can help prevent the early development of WMSDs among physical therapists. Med Pr. 2021;72(4):363–73
    Źródło:
    Medycyna Pracy; 2021, 72, 4; 363-373
    0465-5893
    2353-1339
    Pojawia się w:
    Medycyna Pracy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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