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Wyświetlanie 1-2 z 2
Tytuł:
National Culture Values: reflections on formation process of future leaders in international economic cooperation
Autorzy:
NIKOLIC, MARIJA
LA TORRE, MAURA
LALIĆ, GORAN
Powiązania:
https://bibliotekanauki.pl/articles/628448.pdf
Data publikacji:
2013
Wydawca:
Fundacja Pro Scientia Publica
Tematy:
national business cultures, Serbia-Italy economic future cooperation, in u-ence of national culture values, next generation businessmen
Opis:
The trend towards foreign investments in Serbia has been in rapid progress in recent years. The biggest and most valuable numbers of investments are coming from Italy. The authors’ expectation is that the trend of Italian investments in future will continue; therefore it is of high importance for the representatives of both countries’ business sectors to under-stand and accept differences and similarities to the other country’s business culture. Research of cultural differences between two nations , which are considered like a frame of business culture, helps avoiding possible misunderstandings and improving business cooperation be-tween two countries. Having in mind students of economics and management, on one hand like future leaders of Italian and Serbian business and on other like representatives of the cur-rent education value system in the field of economics and management, this study consists of an application of the 7-D Hofstede Model. The application of the model takes place through the administration of two surveys done by students of Serbian Megatrend University, in Bel-grade, and Italian Università degli Studi Gabriele d’Annunzio, in Pescara
Źródło:
Journal of Education Culture and Society; 2013, 4, 2; 217-226
2081-1640
Pojawia się w:
Journal of Education Culture and Society
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
ANTITUMOR EFFECTS OF VANILLIN BASED CHALCONE ANALOGUES IN VITRO
Autorzy:
Luković, Jovan
Mitrović, Marina
Popović, Suzana
Milosavljević, Zoran
Stanojević-Pirković, Marijana
Anđelković, Marija
Zelen, Ivanka
Šorak, Marija
Muškinja, Jovana
Ratković, Zoran
Nikolić, Ivana
Powiązania:
https://bibliotekanauki.pl/articles/895579.pdf
Data publikacji:
2020-02-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Colorectal cancer
apoptosis
cytotoxicity
Autophagy
chalcones
Opis:
Chalcones, as a large group of organic compounds, are widely implemented in various types of anti-cancer therapeutics. These plant metabolites are present in fruits, vegetables, spices, and have anti-tumor, anti-inflammation, immunomodulation, antibacterial and anti-oxidative activities, as well as many other pharmacological and biological effects. The aim of the present study was to investigate cytotoxic effects, type of cell death and mechanism of action of the newly synthesized vanillin based chalcone analogues, (CH1) and (CH2) on human colon cancer HCT-116 and noncancerous (control) MRC-5 cell lines. In order to compare effects of vanillin based chalcone analogues on investigated cell lines, as reference substances cisplatin (cisPt) and dehydrozingerone (DHZ) were used. Investigation of antitumor effect of chalcone analogues on HCT-116 cells was carried out by three methods MTT assay, flow cytometry and immunofluorescence analysis. The result of our investigation indicated that newly synthesized vanillin based chalcone analogues expressed powerful antitumor effect on cancer cells (HCT-116 cell line), while their effect on healthy cells (MRC-5 cell line) was not statistically significant. Vanillin based chalcone analogues caused overexpression and activation of mitochondrial Bax protein and caspase-3 in HCT-116 cells, indicating that their mechanism of antitumor action was mediated through activation of inner apoptotic pathway. These results indicate possible usefulness of CH1 and CH2 in antitumor therapy whether through its direct cytotoxic effect or as adjuvant therapy. Our results indicate possible usefulness of CH1 and CH2 vanillin based chalcone analogues in antitumor therapy.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 1; 57-67
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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