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    Tytuł:
    Dependence of the yeast Saccharomyces cerevisiae post-reproductive lifespan on the reproductive potential
    Autorzy:
    Zadrag-Tecza, Renata
    Molon, Mateusz
    Mamczur, Jan
    Bilinski, Tomasz
    Powiązania:
    https://bibliotekanauki.pl/articles/1039620.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    aging
    lifespan
    oxidative stress
    yeast
    Opis:
    The lifespan of budding yeast cells is divided into two stages: reproductive and post-reproductive. The post-reproductive stage of the yeast's lifespan has never been characterized before. We have analyzed the influence of various mutations on the post-reproductive (PRLS) and replicative (RLS) lifespans. The results indicate that PRLS demonstrates an inverse relationship with RLS. The observed lack of differences in the total lifespan (TLS) (expressed in units of time) of strains differing up to five times in RLS (expressed in the number of daughters formed) suggests the necessity of revision of opinions concerning the use of yeast as a model organism of gerontology.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 1; 111-115
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The links between hypertrophy, reproductive potential and longevity in the Saccharomyces cerevisiae yeast
    Autorzy:
    Molon, Mateusz
    Zadrag-Tecza, Renata
    Powiązania:
    https://bibliotekanauki.pl/articles/1038822.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    yeast
    lifespan
    longevity
    hypertrophy
    Opis:
    The yeast Saccharomyces cerevisiae has long been used as a model organism for studying the basic mechanisms of aging. However, the main problem with the use of this unicellular fungus is the unit of "longevity". For all organisms, lifespan is expressed in units of time, while in the case of yeast it is defined by the number of daughter cells produced. Additionally, in yeast the phenotypic effects of mutations often show a clear dependence on the genetic background, suggesting the need for an analysis of strains representing different genetic backgrounds. Our results confirm the data presented in earlier papers that the reproductive potential is strongly associated with an increase in cell volume per generation. An excessive cell volume results in the loss of reproductive capacity. These data clearly support the hypertrophy hypothesis. The time of life of all analysed mutants, with the exception of sch9D, is the same as in the case of the wild-type strain. Interestingly, the 121% increase of the fob1D mutant's reproductive potential compared to the sfp1D mutant does not result in prolongation of the mutant's time of life (total lifespan).
    Źródło:
    Acta Biochimica Polonica; 2016, 63, 2; 329-334
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The impact of COVID-19 pandemic and distance learning on physical and mental health of Polish students
    Autorzy:
    Mołoń, Mateusz
    Janda, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/2054539.pdf
    Data publikacji:
    2022-06-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    COVID-19
    distance learning
    e-learning
    students
    Opis:
    Introduction and aim. In Poland, on 25 March 2020, distance learning, which for many people was known only from literature, entered into force. As a result, education could no longer be provided in its current form and was therefore provided online. Therefore, the main aim of the presented research was an attempt to verify the pandemic and distance education impact on students psychophysical conditions and satisfaction. Material and methods. Some primary school students (grades 6th-8th), secondary school students from the Subcarpathian Voivodeship in Poland and also some university students from foreign countries completed an anonymous survey on the impact of the COVID-19 pandemic on their physical and mental condition as well as on some aspects of distance education. The research was conducted in December 2021 and 804 students (Primary and Secondary School) and 64 university students completed the survey. Results. Both the primary and the secondary school students claimed they were quite satisfied with distance education. The mostly approved aspect of online education was the fact that the time of learning was fitted to students’ needs. Difficulties in distance learning indicated by students were mainly connected with their mental health. Therefore, many students suffered from mental health and concentration problems, unwillingness to be active, apathy. The pandemic was also a stress factor for students and a reason why they were in a bad mood. The pandemic was the reason for an increased interest in natural sciences among 31.3% of primary school students, among 20.8% of secondary school students and among 17.3% of university students from foreign countries. Distance education influenced physical health of almost half of the respondents in both types of schools. The pandemic had an impact on mental health state of almost half of primary school students. 65% of secondary school students said that the pandemic influenced both their mental and physical health. In case of university students the pandemic did not influence their physical health in a significant way (65.4%). The study shows that primary school students used the Internet mainly to play games (almost 50% of the respondents), watch films, listen to music, do homework. Online lessons were only 20% of the answers. Conclusion. There has been a significant impact of COVID-19 on students in elementary school, high school, and university. This resulted in negative mental and physical effects. Respondents were stressed, depressed, and unmotivated. Approximately half of them engaged in physical activity very rarely or rarely. Even though they were satisfied with online learning, which was caused by the COVID-2019 pandemic, the greatest problem was mental concentration problems, lack of motivation, and social isolation.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2022, 2; 202-211
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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