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Wyszukujesz frazę "Mogaji, H. O." wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Clinical Manifestations of Plasmodium berghei ANKA Infection in Juvenile Mice: A Short Case Report
Autorzy:
Ajayi, J. B.
Agbeyangi, A. O.
Daniel, A.
Omobolaji, I.
Mogaji, H. O.
Powiązania:
https://bibliotekanauki.pl/articles/1113684.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
ECM
Juvenile
Malaria
Mice
Neonates
Plasmodium berghei
Opis:
Malaria is an important health and development challenge in Africa, Animal models most particularly mice, have long been employed to study malaria pathogenesis. This paper describes clinical manifestations due to Plasmodium berghei ANKA infection in juvenile mice as a model for understanding the complications of congenital malaria in neonates. Forty-five juvenile mice (5-7 days old) were acquired from University College Hospital, Ibadan and injected with 2×107 (0.2 ml) Plasmodium berghei ANKA parasitized red blood cells (PRBCs). The mice were then transported to the study site, kept in well-ventilated cages and fed daily with a balanced ration. Post-P. berghei infection, the mice were monitored daily for mortality. Clinical manifestations of experimental cerebral malaria (ECM) were assessed and confirmed if at least ruffled fur, hunching, wobbly gait, limb paralysis, convulsions, or coma was observed. Each sign was given a score of 1. Animals with scores ≥4 were considered to have severe ECM. In the experiment, 20 (44%) mice were lost due to natural cause (i.e. stress) at day 2. Between day 4 and 9, 25 (56%) of the study mice presented clinical signs of ECM. This included: ruffled fur – 25 (100%), hunching - 21 (84%), wobbly gait - 17 (68%), limb paralysis - 20 (80%), convulsions - 25 (100%). Survival rate and severity of ECM in the mice differs, 22 (88.0%) had severe ECM and 3 (12.0%) had mild ECM. This study has shown that parasite establishment and malaria complications can manifest as early as 4 days’ post P. berghei infection in 5-7 days old mice.
Źródło:
World News of Natural Sciences; 2017, 14; 90-96
2543-5426
Pojawia się w:
World News of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Community Based Management, Environmental Factors and Ecological Patterns Associated with Malaria Parasites Transmission in the Communities of Children Treated with Rectal Artesunate in Ogun State, South-Western Nigeria
Autorzy:
Agbeyangi, O. A.
Sam-Wobo, S. O.
Ekpo, U. F.
Akinloye, O. A.
Mogaji, H. O.
Oluwole, A. S.
Bello, A. A.
Powiązania:
https://bibliotekanauki.pl/articles/1178283.pdf
Data publikacji:
2017
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Community-based management
Ogun State
South-western Nigeria
malaria
mosquitoes vegetation topographic environmental management
Opis:
Community-based case management of malaria has been shown to be effective in reducing mortality and morbidity. Overall total of 183 communities comprising 36(19.7%) communities in Egba Goe-Political Zone (GPZ), 56(30.6%) in Yewa-Awori GPZ, 43(23.5%) in Remo GPZ, and 48(26.2%) in Ijebu GPZ. There was a significant (p = 0.011) difference between preventive measures against malaria adopted for children across LGAs. Involvement in environmental management /sanitation as part of control measure (78.0%) can mostly help in tackling the adverse effects of malaria parasites transmission. They also agreed that mosquitoes breed majorly in stagnant water (77%) and Ponds (74.6%) and they did not always use (54.4%) their ITN/LLITN and their family mostly used ITN/LLITN during rainy season (84.4%). Fresh-water Rain Forest (44.3%) and Lowland Rain Forest (43.2%) are common forest vegetation types. Communities having plains topographical structure were more (91.3%) with close/compact (54.6%) type of settlement and are more densely populated (51.9%). Water bodies present are small rivers (100%). House type common in the communities was mud with iron sheets (100%) and drainage system (36.2%) was not common. Communities Involvement in environmental management/sanitation as part of control measure will reduce malaria parasite transmission.
Źródło:
World Scientific News; 2017, 86, 3; 150-167
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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