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    Wyświetlanie 1-12 z 12
    Tytuł:
    The effect of molding conditions on the quality of geopolymer surfaces
    Autorzy:
    Jaglarz, Janusz
    Wyszyński, Dominik
    Lach, Michał
    Mikuła, Janusz
    Duraj, Ryszard
    Powiązania:
    https://bibliotekanauki.pl/articles/173702.pdf
    Data publikacji:
    2020
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    surface topography
    bidirectional reflectance distribution function
    ellipsometry
    spectrophotometry
    Opis:
    The presented work describes the method of measuring surface topography with application of BRDF (bidirectional reflectance distribution function), ellipsometry and spectrophotometry. This non-contact method enables measurement and analysis of large area surfaces, such as plasters and facades. A standard method of topography analysis does not describe sufficiently all of the interesting features. The visual aspect of the surface evaluation is very important from the functional and utilitarian point of view. The proposed methods of surface analysis enable not only the quantitative evaluation but also indirectly the qualitative properties (visual aspects).
    Źródło:
    Optica Applicata; 2020, 50, 1; 135-146
    0078-5466
    1899-7015
    Pojawia się w:
    Optica Applicata
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Kronika
    Autorzy:
    Kuisz, Jarosław
    Krzysztofek, Katarzyna
    Mikuła, Maciej
    Ożóg, Michał
    Zarzycki, Zdzisław
    Strzała, Marek
    Moniuszko, Adam
    Pomianowski, Piotr
    Pilarczyk, Piotr
    Głuszak, Marcin
    Powiązania:
    https://bibliotekanauki.pl/articles/915846.pdf
    Data publikacji:
    2018-10-12
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Opis:
    -
    Źródło:
    Czasopismo Prawno-Historyczne; 2018, 70, 1; 391-409
    0070-2471
    Pojawia się w:
    Czasopismo Prawno-Historyczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Zagospodarowanie odpadów poprocesowych z termicznego przekształcania odpadów komunalnych
    Autorzy:
    Mikuła, Janusz
    Łach, Michał
    Powiązania:
    https://bibliotekanauki.pl/articles/985968.pdf
    Data publikacji:
    2018
    Wydawca:
    Nowa Energia
    Tematy:
    odpady komunalne
    spalarnia odpadów
    materiały poprocesowe
    municipal waste
    waste incineration plant
    post-trial materials
    Opis:
    Każdego roku na świecie wzrastają nakłady planowanych i realizowanych inwestycji związanych z budową spalarni odpadów komunalnych. Postępowanie takie umożliwia istotną redukcję objętości wytworzonych odpadów w zakresie od 80 do 95%. Jednak również w wyniku procesu spalania powstają różne materiały poprocesowe - popioły i żużle, które zawierają metale ciężkie i inne niebezpieczne substancje i powinny one zostać w odpowiedni sposób zestalone lub przetworzone tak, aby możliwe było ich bezpieczne gospodarcze wykorzystanie
    Źródło:
    Nowa Energia; 2018, 4; 31-34
    1899-0886
    Pojawia się w:
    Nowa Energia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characteristics of sorbent products obtained by the alkaline activation of waste from waste incineration plants
    Autorzy:
    Grela, Agnieszka
    Łach, Michał
    Bajda, Tomasz
    Mikuła, Janusz
    Powiązania:
    https://bibliotekanauki.pl/articles/127590.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Mineralogiczne
    Tematy:
    alkali-activated
    ash from waste incineration
    slag from waste incineration
    Opis:
    Poland, by 2020 430,000 Mg of hazardous waste will be formed annually by the combustion of waste. This waste must be properly managed so as not to endanger the environment. One promising way to manage selected waste is to process it in the synthesis of materials characterised by sorption properties. The results presented in this paper concern the possibility of producing sorbents from waste materials marked with codes 190112 and 190114, which came from two waste incineration plants in Poland. Alkaline activation was performed using two methods: a) hydrothermal, in a solution of 8 M NaOH at 75°C for 24 h; and b) in an autoclave, using a solution of 2 M NaOH at 140°C for 6 h. XRD analyses led to the identification of materials after synthesis of the following zeolite phases: analcime, chabazite and thomsonite. chabazite and analcime can be valuable absorbent materials.
    Źródło:
    Mineralogia; 2017, 48, 1/4; 87-105
    1899-8291
    1899-8526
    Pojawia się w:
    Mineralogia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sprawozdanie z uroczystości jubileuszu 50-lecia pracy naukowej prof. dra hab. Wacława Uruszczaka
    A report on the 50th anniversary of scientific work of Prof., Ph.D. Wacław Uruszczak
    Autorzy:
    Krzysztofek, Katarzyna
    Mikuła, Maciej
    Ożóg, Michał
    Strzała, Marek
    Zarzycki, Zdzisław
    Powiązania:
    https://bibliotekanauki.pl/articles/533042.pdf
    Data publikacji:
    2017
    Wydawca:
    Krakowska Akademia im. Andrzeja Frycza Modrzewskiego
    Źródło:
    Studia z Dziejów Państwa i Prawa Polskiego; 2017, 20; 443-454
    1733-0335
    Pojawia się w:
    Studia z Dziejów Państwa i Prawa Polskiego
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Geo-questionnaire in urban planning – preliminary results of the experimental application in Poland
    Autorzy:
    Bąkowska, Edyta
    Kaczmarek, Tomasz
    Jankowski, Piotr
    Zwoliński, Zbigniew
    Mikuła, Łukasz
    Czepkiewicz, Michał
    Brudka, Cezary
    Powiązania:
    https://bibliotekanauki.pl/articles/1023354.pdf
    Data publikacji:
    2016-09-16
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    geo-questionnaire
    PPGIS
    urban planning
    public participation
    Opis:
    Changes in the attitude of local authorities towards the public participation in the decision making processes have prompted development of new methods of such involvement. As far as the urban planning is concerned, of particular potential is the so-called Public Participation Geographic Information Systems (PPGIS). One of the tools used for the purpose is a geo-questionnaire, combining the benefits of a standard questionnaire and a map, which permits collecting information on particular sites and on the respondents’ ideas on localisation of new objects and functionalities.Within the project “Geoportal supporting public participation in urban planning”, in the years 2015–2016, a study was undertaken to explore the effectiveness and usefulness of the geo-questionnaire. Five pilot studies were performed in the Poznań and Łódź agglomerations. The geo-questionnaires concerned the local spatial management plan in Rokietnica (Poznań agglomeration), landscape protection in Łódź, conception of the transportation system development in Łódź, conception of urban design of the Łazarski Market in Poznań, and the Map of Local Needs in the city center of Poznań. The aim of the study was to present the preliminary results of the initial implementations of geo-questionnaire developed within the project Geoportal supporting public participation in urban planning. The applications of geo-questionnaire have been analysed taking into account the characteristics of implementation areas, characteristics of users, the effectiveness of recruitment methods and opinions about the tool from two points of view: the respondents and the recipients of results.
    Źródło:
    Rozwój Regionalny i Polityka Regionalna; 2016, 35; 37-54
    2353-1428
    Pojawia się w:
    Rozwój Regionalny i Polityka Regionalna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Public Participation GIS for sustainable urban mobility planning: methods, applications and challenges
    Autorzy:
    Czepkiewicz, Michał
    Brudka, Cezary
    Jankowski, Piotr
    Kaczmarek, Tomasz
    Zwoliński, Zbigniew
    Mikuła, Łukasz
    Bąkowska, Edyta
    Młodkowski, Marek
    Wójcicki, Michał
    Powiązania:
    https://bibliotekanauki.pl/articles/1023367.pdf
    Data publikacji:
    2016-09-16
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    PPGIS
    mobility planning
    sustainable mobility
    travel survey
    crowdsourcing
    SUMP (Sustainable Urban Mobility Plan)
    Opis:
    Sustainable mobility planning is a new approach to planning, and as such it requires new methods of public participation, data collection and data aggregation. In the article we present an overview of Public Participation GIS (PPGIS) methods with potential use in sustainable urban mobility planning. We present the methods using examples from two recent case studies conducted in Polish cities of Poznań and Łodź. Sustainable urban mobility planning is a cyclical process, and each stage has different data and participatory requirements. Consequently, we situate the PPGIS methods in appropriate stages of planning, based on potential benefits they may bring into the planning process. We discuss key issues related to participant recruitment and provide guidelines for planners interested in implementing methods presented in the paper. The article outlines future research directions stressing the need for systematic case study evaluation.
    Źródło:
    Rozwój Regionalny i Polityka Regionalna; 2016, 35; 9-35
    2353-1428
    Pojawia się w:
    Rozwój Regionalny i Polityka Regionalna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Transcriptional changes between uninflamed ulcerative colitis and familial adenomatous polyposis pouch mucosa can be attributed to an altered immune response
    Autorzy:
    Paziewska, Agnieszka
    Horbacka, Karolina
    Goryca, Krzysztof
    Mikula, Michal
    Jarosz, Dorota
    Dabrowska, Michalina
    Krokowicz, Piotr
    Karon, Jacek
    Ostrowski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1039136.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    ulcerative colitis
    familial adenomatous polyposis
    pouch
    gene expression
    immune response
    Opis:
    A total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is considered the surgery of choice for definitive management of familial adenomatous polyposis (FAP) and some patients with ulcerative colitis (UC). However, this surgical treatment is often associated with pouchitis, a long-term complication that occurs mostly in UC patients. The purpose of this study was to better define the molecular background of pouchitis. A microarray-based survey was performed using pouch mucosal samples collected from 28 and 8 patients undergoing surgery for UC and FAP, respectively. There were 4,770 genes that significantly differentiated uninflamed from inflamed mucosal samples, and their functional features were represented mostly by metabolic and cell proliferation pathways. In contrast, functional analyses of aberrantly expressed genes between UC and FAP samples, irrespective of mucosal inflammation status, revealed multiple pathways and terms that were linked to changes in immune response. Interestingly, the comparison of uninflamed UC and FAP samples identified a set of 29 altered probe sets, including an inflammation-related transcript encoding a Charcot-Leyden crystal (CLC) protein. The most distinct changes in gene expression profiles differentiating uninflamed UC and FAP pouch mucosal samples were attributed to the Gene Ontology category innate immune response. Our study confirmed that alterations in immune responses can be found between patients who underwent surgery for UC and FAP, independent of the pouch inflammation status. This observation may be important when managing IPAA patients.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 1; 69-75
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pre-analytical-related variability influencing serum peptide profiles demonstrated in a mass spectrometry-based search for colorectal and prostate cancer biomarkers
    Autorzy:
    Karczmarski, Jakub
    Rubel, Tymon
    Mikula, Michal
    Wolski, Jan
    Rutkowski, Andrzej
    Zagorowicz, Edyta
    Dadlez, Michal
    Ostrowski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1039544.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    mass spectrometry; peptidome; serum; cancer; fibrinopeptide A
    apolipoprotein A-IV
    Opis:
    Although the degradome, which comprises proteolytic fragments of blood proteins, presents a potential source of diagnostic biomarkers, studies on cancer peptide biomarkers have provided inconsistent conclusions. In the present study, we reevaluated the usefulness of serum degradome analyses for searching peptide cancer biomarker candidates. Particular attention was paid to pre-analytical factors influencing the variability of determined peptide levels, including clotting time and control group selection. Studies were conducted on 44 and 86 serum samples collected from cancer patients and healthy individuals, respectively, using liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS)-based analyses. We identified 1373 unique peptides, nearly 40% of which originated from five blood proteins: fibrinogen alpha chain, apolipoprotein A-IV (APOA4), complement C3, apolipoprotein A-I, and alpha-1-antitrypsin. A set of 118 and 88 peptides exhibited highly significant differences (adjusted p-value ≤ 0.01 and fold change ≥ 2) in pair-wise comparisons of control vs. prostate cancer and control vs. colorectal cancer, respectively, with 37 peptides displaying a consistent direction of change for these pair-wise comparisons. The levels of 67 peptides differed significantly in serum samples collected from healthy individuals immediately prior to colonoscopy and those who underwent colonoscopic examination at least four weeks earlier. Of them, 49 peptides originated from APOA4. Whereas earlier studies, including ours, have utilized fragments of fibrinopeptide A (FPA) to distinguish cancer from healthy cases, here we show that their absolute abundance is a sensitive indicator of clotting time. These observations may have implications for future serum peptidome studies since these issues have not previously been recognized.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 3; 417-425
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gene expression alterations induced by low molecular weight heparin during bowel anastomosis healing in rats
    Autorzy:
    Krześniak, Natalia
    Paziewska, Agnieszka
    Rubel, Tymon
    Skrzypczak, Magdalena
    Mikula, Michał
    Dzwonek, Artur
    Goryca, Krzysztof
    Wyrwicz, Lucjan
    Jarosz, Dorota
    Laubitz, Daniel
    Woszczyński, Marek
    Bielecki, Krzysztof
    Ostrowski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1039955.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    heparins
    gene expression
    wound healing
    microarrays
    Opis:
    Colon anastomosis is therapeutically challenging because multiple, usually undetectable factors influence a spectrum of repair mechanisms. We hypothesized that low molecular weight heparins, routinely administered perioperatively, may differentially affect gene expression related to colon healing. Twenty pairs of untreated and enoxaparin-treated rats underwent left-side hemicolectomy with a primary end-to-end anastomosis. Normal colon and anastomotic bowel segments were resected on day 0 and on days 1, 3, 5, and 7 after surgery, respectively. Serial anastomosis transverse cross-sections were evaluated microscopically and by microarray (Rat Genome 230 2.0, Affymetrix). Differentially expressed probe sets were annotated with Gene Ontology. We also examined the influence of enoxaparin on fibroblast proliferation and viability in vitro. Among the 5476 probe sets, we identified differential expression at each healing time point, yielding 79 subcategories. Most indicated genes were involved in wound healing, including multicellular organismal development, locomotory behavior, immune response, cell adhesion, inflammatory response, cell-cell signaling, blood vessel development, and tissue remodeling. Although we found no intensity differences in histological features of healing between enoxaparin-treated and control rats, treatment did induce significant expression changes during early healing. Of these changes, 83 probe sets exhibited at least twofold changes and represented different functional annotations, including inflammatory response, regulation of transcription, regulation of apoptosis, and angiogenesis. Fibroblast culture confirmed an anti-viability effect of enoxaparin. Enoxaparin affects colon wound-related gene expression profiles, but further studies will resolve whether heparin treatment is a risk factor after intestinal surgery, at least in some patients.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 1; 79-87
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Barretts esophagus associates with a variant of IL23R gene
    Autorzy:
    Gaj, Pawel
    Mikula, Michal
    Wyrwicz, Lucjan
    Regula, Jaroslaw
    Ostrowski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1040756.pdf
    Data publikacji:
    2008
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Barrett's esophagus
    risk
    SNP
    IL23R
    association study
    Opis:
    Gastroesophageal reflux disease is regarded as a spectrum of diseases: non-erosive reflux disease (NERD), erosive reflux disease (ERD), and the far end of the spectrum represented by patients with Barrett's esophagus. Among predisposing factors, both risk and protective polymorphic variants of several genes may influence the clinical outcomes of reflux disease. Consequently, different molecular mechanisms are likely to underlie the development of clinical variants of reflux disease. Ninety six patients with reflux disease were screened for polymorphisms of CARD15, SLC22A4 (OCTN1), SLC22A5 (OCTN2), DLG5, ATG16L1 and IL23R genes which had previously been found to associate with immune-mediated chronic inflammatory disorders. While none of the polymorphisms were associated with NERD or ERD, the 1142G/A variant of the IL23R gene was found to be a risk variant in Barrett's esophagus patients. The IL23/IL23R pathway may modulate STAT3 transcriptional activity which is an essential regulator not only of immune-mediated inflammation, but also of inflammatory-associated apoptosis resistance. Although the mechanisms of metaplastic transition of inflamed squamous epithelium are undetermined as yet, our findings suggest potential involvement of alternations in the IL23/IL23R pathway as a molecular background of Barrett's esophagus development.
    Źródło:
    Acta Biochimica Polonica; 2008, 55, 2; 365-369
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mitochondria-associated satellite I RNA binds to hnRNP K protein
    Autorzy:
    Klimek-Tomczak, Karolina
    Mikula, Michał
    Dzwonek, Artur
    Paziewska, Agnieszka
    Wyrwicz, Lucjan
    Hennig, Ewa
    Ostrowski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1041284.pdf
    Data publikacji:
    2006
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    hnRNP K protein
    SAGE
    mitochondria
    satellite I RNA
    Opis:
    hnRNP K protein, which localizes to the nucleus, cytoplasm and mitochondria, is involved in the various cellular processes that compose gene expression. We used a SAGE-based assay to profile RNAs associated with hnRNP K protein in rat mitochondria. RNA was isolated from mitoplasts obtained from highly purified and RNase-treated mitochondria. Total RNA and RNA associated with hnRNP K protein were then used as input material for generating two SAGE libraries. Mitochondrion-derived tags isolated from the total mitoplast RNA library represented 86.3%, while those isolated from the library constructed from RNA associated with hnRNP K protein represented only 28.2% of selected tags. Thus, an unexpected number of nuclear-encoded RNAs were purified from mitochondria. Many of these transcripts were co-purified with hnRNP K protein, and high levels of nuclear-encoded RNAs co-immunoprecipitating with K protein corresponded to elevated hnRNP K protein levels of the organelle. The most abundant RNAs that were co-purified with hnRNP K protein represented transcripts originating from satellite I DNA. While satellite I RNA levels were higher in the nucleus and cytoplasm than in mitochondria, the most abundant binding of satellite I transcripts to hnRNP K protein was found in mitochondria. The role of satellite I RNA in mitochondria remains to be elucidated.
    Źródło:
    Acta Biochimica Polonica; 2006, 53, 1; 169-178
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-12 z 12

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