Autor: Markowicz, Joanna - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Properties of modulus of monotonicity and Opial property in direct sums
Autorzy:: Markowicz, Joanna
Prus, Stanisław
Powiązania:: https://bibliotekanauki.pl/articles/747142.pdf
Data publikacji:: 2017
Wydawca:: Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:: Banach lattice
modulus of monotonicity
direct sum
non-strict Opial property
Opial property
Opis:: We give an example of a Banach lattice with a non-convex modulus of monotonicity, which disproves a claim made in the literature. Results on preservation of the non-strict Opial property and Opial property under passing to general direct sums of Banach spaces are established.
Źródło:: Annales Universitatis Mariae Curie-Skłodowska, sectio A – Mathematica; 2017, 71, 2
0365-1029
2083-7402
Pojawia się w:: Annales Universitatis Mariae Curie-Skłodowska, sectio A – Mathematica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 2.

Tytuł:: Conditions influencing incoming global solar radiation in Hornsund (Spitsbergen) in spring 2015
Autorzy:: Uscka-Kowalkowska, Joanna
Przybylak, Rajmund
Markowicz, Krzysztof M.
Araźny, Andrzej
Powiązania:: https://bibliotekanauki.pl/articles/2042154.pdf
Data publikacji:: 2017
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: aerosol optical depth
Arctic
cloudiness
global solar radiation
Spitsbergen
sunshine duration
Źródło:: Polish Polar Research; 2017, 38, 3; 333-349
0138-0338
2081-8262
Pojawia się w:: Polish Polar Research
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 3.

Tytuł:: STUDIES TOWARDS HEMOCOMPATIBILITY OF POLYAMINE CONJUGATES WITH BICYCLIC SYSTEMS
Autorzy:: Szumilak, Marta
Markowicz-Piasecka, Magdalena
Mikiciuk-Olasik, Elzbieta
Stanczak, Andrzej
Sikora, Joanna
Powiązania:: https://bibliotekanauki.pl/articles/895466.pdf
Data publikacji:: 2018-08-31
Wydawca:: Polskie Towarzystwo Farmaceutyczne
Tematy:: coagulation
biocompatibility
fibrinolysis
erythrotoxicity
polyamine conjugates
Opis:: Assessing hemocompatibility of anticancer drug candidate is very important task due to the fact that coagulation disorders are often correlated with malignancy or induced by chemotherapy. The aim of this study was to examine the influence of some polyamine conjugates with bicyclic systems on the process of coagulation and fibrinolysis. In addition their effect on the healthy human erythrocytes (RBCs) was assessed. Prothrombin Time (PT), Activated Partial Tromboplastin Time (APTT), clot formation and lysis test (CL-test) were performed to evaluate the influence of some polyamine conjugates on plasma hemostasis. The effects of tested compounds on RBCs were assessed using hemolysis assays and microscopy studies. APTT and PT examination revealed that all tested compounds apart from the highest concentrations of compounds 3 and 5 did not exert significant effects on intrinsic and extrinsic coagulation pathways. Despite their substantial influence on the kinetic parameters of the process of clot formation and fibrinolysis, the examined compounds, over the entire concentration range, did not alter the overall potential of clot formation and lysis (CLAUC) suggesting that they might be regarded as biocompatible concerning plasma hemostasis. At potential therapeutic concentrations (constituting IC50 value for MCF-7 cells) tested polyamine conjugates showed no adverse effects on the membranes of RBCs. Promising antiproliferative activity of representative polyamine conjugates together with their hemocompatibility make them good anticancer drug candidates for further preclinical evaluation.
Źródło:: Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 861-874
0001-6837
2353-5288
Pojawia się w:: Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Skocz do pozycji: 4.

Tytuł:: Nonviral transfection of human umbilical cord blood dendritic cells is feasible, but the yield of dendritic cells with transgene expression limits the application of this method in cancer immunotherapy
Autorzy:: Markowicz, Sergiusz
Niedzielska, Joanna
Kruszewski, Marcin
Ołdak, Tomasz
Gajkowska, Agnieszka
Machaj, Eugeniusz
Skurzak, Henryk
Pojda, Zygmunt
Powiązania:: https://bibliotekanauki.pl/articles/1041291.pdf
Data publikacji:: 2006
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: CD34+ cells
umbilical cord blood
green fluorescent protein
electroporation
gene transfer
dendritic cells
Opis:: Dendritic cells (DC) generated from human umbilical cord blood might replace patients' DC in attempts to elicit tumor-specific immune response in cancer patients. We studied the efficiency of transfection of human cord blood DC with plasmid DNA carrying the enhanced version of green fluorescent protein (EGFP) as a reporter gene, to test if nonviral gene transfer would be a method to load DC with protein antigens for immunotherapy purposes. Cord blood mononuclear cells were cultured in serum-free medium in the presence of granulocyte-monocyte colony stimulating factor (GM-CSF), stem cell factor (SCF) and Flt-3 ligand (FL), to generate DC from their precursors, and thereafter transfected by electroporation. Maturation of DC was induced by stimulation with GM-CSF, SCF, FL and phorbol myristate acetate (PMA). Transfected DC strongly expressed EGFP, but transfection efficiency of DC, defined as HLA-DR+ cells lacking lineage-specific markers, did not exceed 2.5%. Expression of the reporter gene was also demonstrated in the DC generated from transfected, purified CD34+ cord blood cells, by stimulation with GM-CSF, SCF, FL, and tumor necrosis factor α (TNF-α). Transfection of CD34+ cells was very efficient, but proliferation of the transfected cells was much reduced as compared to the untransfected cells. Therefore, the yield of transgene-expressing DC was relatively low. In conclusion, nonviral transfection of cord blood DC proved feasible, but considering the requirements for immunotherapy in cancer patients, transfection of differentiated DC or generation of DC from transfected hematopoietic stem cells provide only a limited number of DC expressing the transgene.
Źródło:: Acta Biochimica Polonica; 2006, 53, 1; 203-212
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Zmień widok

na półce

Informacja

Wyszukujesz frazę "Markowicz, Joanna" wg kryterium: Autor

Źródło danych

Dostawca treści

Kolekcja

Rok wydania

Wydawca

Temat

Autor

Typ dokumentu

Język