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Wyszukujesz frazę "Marchlewicz, Mariola" wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Conjugated linoleic acids regulate triacylglycerol and cholesterol concentrations in macrophages/foam cells by the modulation of CD36 expression
Autorzy:
Stachowska, Ewa
Baskiewicz, Magdalena
Marchlewicz, Mariola
Czupryńska, Katarzyna
Kaczmarczyk, Mariusz
Wiszniewska, Barbara
Machaliński, Bogusław
Chlubek, Dariusz
Powiązania:
https://bibliotekanauki.pl/articles/1040388.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
CD36
triacylglycerols
foam cells
cholesterol
PPAR
CLA
macrophages
Opis:
Atherosclerosis is an inflammatory disease characterised by the accumulation of lipids and their metabolites in the artery wall. During inflammation circulating LDL are taken up by macrophages through two major scavenger receptors: CD36 and scavenger receptor A (SRA). Fatty acids that are common in food, e.g. linoleic acid and n-3 unsaturated fatty acids can modulate expression of CD36 on the macrophage surface. Conjugated linoleic acid isomers (CLA) that originate from the human diet, have demonstrated antiatherogenic properties in several experiments. Animal study evidenced that CLA could induce resolution of plaque by activation of peroxisome proliferator activated receptors and down-regulation of pro-inflammatory genes. Less unequivocal results were obtained in human studies (on the CLA effects on the inflammatory process). Therefore in this study we investigated the influence of CLA on CD36 expression and lipid accumulation in human macrophages. Macrophages were incubated with 30 µM cis-9,trans-11 CLA, trans-10,cis-12 CLA or linoleic acid for 48 h. After that, expression of CD36 as well as accumulation of lipids were measured by flow cytometry, microscopy and a spectroscopic method. We demonstrate that both cis-9,trans-11 C 18:2 CLA and linoleic acid slightly elevated expression of CD36, whereas second isomer - trans-10,cis-12 CLA - did not. Nevertheless, only trans-10,cis-12 CLA triggered delipidation of macrophages, that is decreased triacylglycerols concentration. Also in human adipocytes, trans-10,cis-12 CLA causes cell delipidation by reduction of PPAR receptor expression. We propose a similar mechanism for human macrophages/foam cells.
Źródło:
Acta Biochimica Polonica; 2010, 57, 3; 379-384
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Health Risks Related to Tattoo Procedure
Autorzy:
Tuchowska, Aleksandra
Kruk, Joanna
Sagan, Paulina
Duchnik, Ewa
Marchlewicz, Mariola
Powiązania:
https://bibliotekanauki.pl/articles/1030679.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
allergic reactions
health risk
infection
patient awareness
tattoo
Opis:
Nowadays, tattoos have become a very common form of body decoration. However, they carry a risk of numerous complications – ranging from allergies to cancer. The study was divided into two parts. Adult persons, 156 men and 149 women, with one or more tattoos, participated in the first part of study. Anonymous respondents filled in the authorial questionnaire consisting of 14 questions and posted on the Internet. The second part of the study concerned of tattoo salons (n=38) employees. The aim of the study was to examine the awareness of people who are tattooing the body about the possible risks associated with such intervention, as well as the ability to obtain information from tattoo artists and analyze client cards in terms of the most important information about tattooing. The second part of the study was devoted to the analysis of the tattoo consent forms. Most tattoo salons clients claimed that they signed a tattoo consent and were informed about contraindications and possible complications. However, only in very rare cases allergic tests were reported. There were few cases of complications among the respondents. There is a need to educate both the clients of tattoo salons and tattooists themselves. Attention should be paid to the necessity of filling in the informed consent.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2019, 26, 2; 41-46
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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