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Wyświetlanie 1-3 z 3
Tytuł:
Mykosterole — charakterystyka i znaczenie biologiczne
Mycosteroles — Characteristics and Biological Importance
Autorzy:
SUŁKOWSKA-ZIAJA, Katarzyna
HAŁASZUK, Patrycja
MASTEJ, Małgorzta
PIECHACZEK, Małgorzata
MUSZYŃSKA, Bożena
Powiązania:
https://bibliotekanauki.pl/articles/1034021.pdf
Data publikacji:
2016
Wydawca:
Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
Tematy:
"edible mushrooms"
"ergosterol"
Basidiomycota
mycosterols"
Opis:
A group of natural sterols isolated from mushrooms are mycosterols, of which derivatives the most interesting is ergosterol (5,7,22-ergostatrien-3β-ol) and its peroxide, which are presented in the fruiting bodies of most of the representatives of the Basidiomycota taxon. Mushroom sterols are synthesized in a similar way, but the reaction sequence, which is squalene metabolism and the stereochemistry of the major products are different. As with many derivatives of isoprene, the basic unit of the synthesis of sterols is isopentenyl pyrophosphate (IPP), which in turn is synthesized from acetyl-CoA by alternately pass away of mevalonic acid. Mycosteroles, they are considered beneficial compounds that have health promoting effects. It has been proven their ability to lower serum cholesterol, may also be effective in the prevention of certain types of cancer. Ergosterol, which is common in mushrooms, as peroxidation products thereof, also exhibits many beneficial effects. It may have the potential health benefits and influence on the improvement of essential physiological functions of human body, including reduced pain associated with the activity of inflammation, reduction in the incidence of cardiovascular disease, inhibition of the enzyme cyclooxygenase (COX) and lowering cholesterol levels. It also has antioxidant properties and inhibit the growth of fungi and bacteria.
Źródło:
Medicina Internacia Revuo; 2016, 27, 106; 26-34
0465-5435
Pojawia się w:
Medicina Internacia Revuo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A relationship between serological markers of chronic C. pneumoniae and CMV infection and hsp60 in patients with atherosclerotic carotid stenosis
Autorzy:
Rabczyński, Maciej
Fiodorenko-Dumas, Żanna
Mastej, Krzysztof
Dumas, Ilias
Adamiec, Rajmund
Paprocka-Borowicz, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1039140.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
anti-hsp60
atherogenesis
hsCRP
C. pneumoniae
CMV
carotid artery
Opis:
A number of epidemiological studies conducted over the last decade indicate a relationship between specific pathogen infections and the development of atherosclerosis, although no pathogenetic pathways connecting these two have been determined. Recent reports support the role of heat shock proteins (HSPs) in atherogenesis. The HSPs are also believed to be a link between the infection and the development of atherosclerotic lesions. The aims of study: Immunohistochemical evaluation of carotid artery segments to show the relationship between the presence of heat shock proteins and the serum levels of anti-hsp60 antibodies. An attempt to demonstrate a relationship between an expression of chronic C. pneumoniae and CMV antigens. Material and Methods: The study included 41 patients qualified for carotid artery endarterectomy and 18 healthy volunteers of corresponding age. Levels of anti- hsp60, anti-C. pneumoniae IgA and IgG, anti-CMV IgG antibodies as well as hsCRP were determined. Results: The mean serum levels of anti-hsp60 antibodies were higher in patients with advanced atherosclerosis as compared to healthy volunteers (55.3±64.1 vs 32.8±29.8; p < 0.05). There was a strong correlation between anti-hsp60 antibodies and the expression of hsp60 in carotid arterial wall, as confirmed by immunohistochemical evaluation. The study group showed statistically significant higher levels of hsCRP. Furthermore, statistically significant higher serum levels of anti-C. pneumoniae IgG and IgA as well as anti-CMV IgG antibodies were found in the study group as compared to controls. No correlation was shown between the markers of chronic infection induced by the tested pathogens and serum levels of anti-HSP and hsCRP. Conclusions: Higher protein expression in vascular walls is closely correlated with the level of anti-hsp60. At the same time, no significant relationship between anti-hsp60 antibodies and serological markers of infection was observed, which may only indicate an indirect role of infection in the assessment of breaking the immunological tolerance against autologous HSPs.
Źródło:
Acta Biochimica Polonica; 2015, 62, 1; 89-95
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Karotenoidy rola biologiczna i występowanie w owocnikach grzybów
Biological function of carotenoids and their occurrence in the fruiting bodies of mushrooms
Autorzy:
Muszyńska, Bożena
MASTEJ, Małgorzata
SUŁKOWSKA – ZIAJA, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1033726.pdf
Data publikacji:
2016
Wydawca:
Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
Tematy:
"antioxidant activity"
"carotenoids"
"edible mushrooms"

β-carotene"
Opis:
Due to the valuable properties of carotenoidsthe interest in new methods of obtaining them is still increasing. For this purpose, since the 60s of the twentieth century, scientists conducted numerous studies to recognize the processes in which carotenoids could be produced . Carotenoids, revealing a strong antioxidant activity, act as free radical scavengers. These compounds can support many beneficial processes such as the stimulation of the immune system, the modulation of intracellular signaling pathways, the regulation of the cell cycle and apoptosis as well as theregulation of growth factors. Carotenoids were determined by spectrophotometric analysis in the following fungal species: Leucopaxillus giganteus, Sarcodon imbricatus, Lactarius piperatus, Lactarius deliciosus, Agaricus arvensis, Agaricus bisporus, Agaricus romagnesii, Agaricus silvaticus, Agaricus silvicola, Hypholoma fasciculare, Calocybe gambosa, Craterellus cornucopioides, Marasmius oreades. High performance liquid chromatography (HPLC) coupled with a UV detector detected β,β-carotene in Agaricus bisporus, Polyporus squamosus, Lepista nuda, Russula delica, Verpa conica, Pleurotus ostreatus and Hypsizgus marmoreus. β-carotene and lycopene were also found in three wild species of edible mushrooms: Leucopaxillus giganteus, Sarcodon imbricatus and Agaricus arvensi. These compounds were isolated in several species of the family Cantharellus as well. One example is Cantharellus cibarius, which contains mainly β,β-carotene and minor amounts of lycopene, α-carotene and other carotenoids, which may be δ – and γ – isomers.
Źródło:
Medicina Internacia Revuo; 2016, 27, 107; 113-122
0465-5435
Pojawia się w:
Medicina Internacia Revuo
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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