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Wyszukujesz frazę "Liu, Zhiming" wg kryterium: Autor


Wyświetlanie 1-3 z 3
Tytuł:
Upregulation of GRP78 and caspase-12 in diastolic failing heart
Autorzy:
Sun, Yingying
Liu, Guanghui
Song, Tao
Liu, Fang
Kang, Weiqiang
Zhang, Yun
Ge, Zhiming
Powiązania:
https://bibliotekanauki.pl/articles/1040708.pdf
Data publikacji:
2008
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
caspase-12
diastolic heart failure
GRP78; hypertension
apoptosis
Opis:
Background: The endoplasmic reticulum (ER) fulfills multiple cellular functions. Various stimuli can potentially cause ER stress (ERS). ERS is one of the intrinsic apoptosis pathways and apoptosis plays a critical role in hypertension. Glucose regulated protein 78 (GRP78) has been widely used as a marker for ERS and caspase-12 mediated apoptosis was a specific apoptotic pathway of ER. The expression of GRP78 and caspase-12 remains poorly understood in the diastolic heart failure resulting from hypertension. Methods: We used spontaneously hypertensive rats (SHRs) to establish a model of diastolic heart failure, and performed immunohistochemistry, western blot, and real-time PCR to analyze GRP78 and caspase-12. Results: We found that GRP78 and caspase-12 had enhanced expression at protein and mRNA levels. Conclusions: These results suggest that GRP78 and caspase-12 were upregulated in cardiomyocytes and ERS can contribute to cardiac myocyte apoptosis in the diastolic heart failure resulting from hypertension.
Źródło:
Acta Biochimica Polonica; 2008, 55, 3; 511-516
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of dynamic characteristics of an experimental bench of high-pressure water fracturing assisted cutting
Autorzy:
Liu, Zhiming
Zhang, Qiang
Sun, Yuliang
Liu, Junming
Powiązania:
https://bibliotekanauki.pl/articles/2200892.pdf
Data publikacji:
2023
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
high-pressure water fracturing
experimental bench
dynamic characteristics
Opis:
Aiming at the problem that the cutting efficiency of a drum shearer is low when mining hard coal seams, an experimental bench of high-pressure water fracturing assisted cutting is designed. Compared with normal ones, the maximum equivalent stress of the improved experimental bench is reduced by 55.38%, and the maximum total deformation is reduced by 27.23%. According to the results of dynamic response analysis, it is concluded that the experimental bench of high-pressure water fracturing assisted cutting is stable and reliable under extreme working conditions, and meets design requirements for strength and stiffness.
Źródło:
Journal of Theoretical and Applied Mechanics; 2023, 61, 2; 317--330
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of Wear Resistance in Polycrystalline and Monocrystalline Iron
Autorzy:
Liu, Zhiming
Zhang, Qiang
Liu, Fangying
Zhang, Hezhe
Powiązania:
https://bibliotekanauki.pl/articles/2203723.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
molecular dynamics
polycrystalline
centro symmetric analysis
abrasive wear
Opis:
In the present research, we used molecular dynamics simulation to determine the effect of cutting parameters on micro-grain boundary structures and Burgers vector distribution in single crystal iron and polycrystalline iron materials. The result showed that the destruction of the lattice in polycrystalline iron caused by the cutting tool was restricted to the contact surface area. In addition, in the precision machining process, a higher refining grain was observed on the iron surface. During the cutting process of single crystal iron, large-scale slip occurred along the <111> crystal direction on the {110} crystal plane. And the slip presented an annular shape.
Źródło:
Archives of Metallurgy and Materials; 2023, 68, 1; 15--20
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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