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    Wyświetlanie 1-14 z 14
    Tytuł:
    Study on flotation behavior and mechanism of separating chalcopyrite and Molybdenite with ethyl mercaptoglycolate as inhibitor
    Autorzy:
    Yang, Xiao-Feng
    Xu-Zhao
    Liu, Yao-Yao
    Powiązania:
    https://bibliotekanauki.pl/articles/24085868.pdf
    Data publikacji:
    2023
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    ethyl thioglycolate
    chalcopyrite
    molybdenite
    inhibitor
    separation
    Opis:
    The effect of ethyl thioglycolate organic small molecule inhibitors on chalcopyrite molybdenite flotation behaviour is investigated via single mineral micro-flotation tests, zeta potential tests, and X-ray photoelectron spectroscopy (XPS) analysis. Results of the flotation test indicate that ethyl thioglycolate organic small-molecule inhibitors can effectively separate Cu and Mo and selectively inhibit chalcopyrite under weak alkaline conditions. Infrared spectroscopy and XPS analysis show that hydrophilic functional groups C=O and -COOH in the ethyl thioglycolate organic small molecules can chemically adsorb onto the chalcopyrite surface. Moreover, ethyl thioglycolate has no obvious effect on zeta potential of molybdenite. Therefore, ethyl thioglycolate can effectively separate chalcopyrite and molybdenite.
    Źródło:
    Physicochemical Problems of Mineral Processing; 2023, 59, 2; art. no. 162824
    1643-1049
    2084-4735
    Pojawia się w:
    Physicochemical Problems of Mineral Processing
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Robust L2 consensus of high-order swarm systems with time-varying delays
    Autorzy:
    Xi, J
    Yao, Z
    Liu, G.
    Zhong, Y.
    Powiązania:
    https://bibliotekanauki.pl/articles/205770.pdf
    Data publikacji:
    2014
    Wydawca:
    Polska Akademia Nauk. Instytut Badań Systemowych PAN
    Tematy:
    consensus
    swarm system
    uncertainty
    time delay
    disturbance rejection
    Opis:
    Consensus problems for high-order continuous-time swarm systems in directed networks with time delays, uncertainties and external disturbances are investigated. Firstly, the state space of a swarm system is decomposed into a consensus subspace (CS) and a complement consensus space (CCS). A necessary and sufficient condition for the system with time delays and uncertainties to achieve consensus is presented based on the state projection on CCS, and an explicit expression of the consensus function is shown on the basis of the state projection on CS. Then, a sufficient condition for the system to achieve consensus with a desired L2 performance is given. Finally, numerical simulations are shown to demonstrate theoretical results.
    Źródło:
    Control and Cybernetics; 2014, 43, 1; 59-77
    0324-8569
    Pojawia się w:
    Control and Cybernetics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    An improved algorithm for the series step-up method based on a linear three-ports network
    Autorzy:
    Liu, Hao
    Chen, Lixue
    Wang, Xue
    Yao, Teng
    Gu, Xiong
    Powiązania:
    https://bibliotekanauki.pl/articles/2106422.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    voltage transformer
    traceability method
    calibration
    high voltage
    Opis:
    Capacitive leakage and adjacent interference are the main influence sources of the measuring error in the traditional series step-up method. To solve the two problems, a new algorithm was proposed in this study based on a three-ports network. Considering the two influences, it has been proved that response of this three-ports network still has characteristics of linear superposition with this new algorithm. In this threeport network, the auxiliary series voltage transformers use a two-stage structure that can further decrease measurement uncertainty. The measurement uncertainty of this proposed method at 500/√3 kV is 6.8 ppm for ratio error and 7 μrad for phase displacement ( k = 2). This new method has also been verified by comparing its results with measurement results of the PTB in Germany over the same 110/√3 kV standard voltage transformer. According to test results, the error between the two methods was less than 2.7 ppm for ratio error and 2.9 μrad for phase displacement.
    Źródło:
    Metrology and Measurement Systems; 2022, 29, 2; 301--313
    0860-8229
    Pojawia się w:
    Metrology and Measurement Systems
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of a nonlinear tuned mass damper by using the multi-scale method
    Autorzy:
    Liu, Junfeng
    Yao, Ji
    Huang, Kun
    Zhang, Qing
    Ze, Li
    Powiązania:
    https://bibliotekanauki.pl/articles/2104766.pdf
    Data publikacji:
    2022
    Wydawca:
    Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
    Tematy:
    nonlinear characteristics
    complex average method
    multi-scale method
    nonlinear design
    control performance
    Opis:
    A tuned mass damper is a kind of vibration damping device which has been widely used in tall buildings, machinery, bridges, aerospace engineering and other fields. In practical engineering applications, due to large deformation caused by large displacement, errors in engineering constructions and the existence of limit devices, the structure and tuned mass dampers inevitably produce some nonlinear characteristics, but these nonlinearities are often ignored. The results of this study confirm that the nonlinearity of the structure and the mass damper should be considered in the process of optimal frequency design, otherwise there will be a large deviation between the design optimal frequency of the mass damper and the actual optimal frequency. In this paper, nonlinear characteristics of the tuned mass damper and the main structure are considered. The first-order differential equations are obtained by using the complex average method, and the nonlinear equations of the tuned mass damper system are derived by using the multi-scale method. On this basis, the parameters are determined. The numerical results show that the error of the approximate solution method is small in the given example. The nonlinear tuned mass damper with nonlinear design exhibits a better control performance.
    Źródło:
    Journal of Theoretical and Applied Mechanics; 2022, 60, 3; 463--477
    1429-2955
    Pojawia się w:
    Journal of Theoretical and Applied Mechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Multi-source and multi-target iron ore blending method in open pit mine
    Autorzy:
    Yao, Jiang
    Liu, Chunhui
    Huang, Guichen
    Xu, Kai
    Yuan, Qingbo
    Powiązania:
    https://bibliotekanauki.pl/articles/2203345.pdf
    Data publikacji:
    2022
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    ruda żelaza
    kopalnia odkrywkowa
    kopalnia żelaza
    iron ore blending
    multi-source and multi-target
    open pit mine
    Opis:
    Iron ore blending in an open-pit mine is an important means to ensure ore grade balance and resource recycling in iron mine industrial production. With the comprehensive recovery and utilisation of resource mining, the multi-source and multi-target ore blending method has become one of the focuses of the mining industry. Scientific and reasonable ore blending can effectively reduce the transportation cost of the enterprise. It can also ensure that the ore grade, washability index and iron carbonate content meet the requirements of the concentrator and significantly improve the comprehensive utilisation rate and economic benefits of the ore. An ore blending method for open-pit iron ore is proposed in this paper. The blending method is realised by establishing the ore blending model. This model aims to achieve maximum ore output and the shortest transportation distance, ore washability index, total iron grade, ferrous iron grade and iron carbonate content after the ore blending meets the requirements. This method can meet the situation of a single mine to a single concentrator and that of a single mine to multiple concentrators. According to the results of ore blending, we can know the bottleneck of current production. Through targeted optimisation management, we can tap the production potential of an open-pit mine.
    Źródło:
    Archives of Mining Sciences; 2022, 67, 4; 631--644
    0860-7001
    Pojawia się w:
    Archives of Mining Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Investigation on Irreversible Expansion of 1,3,5-Triamino-2,4,6-trinitrobenzene Cylinder
    Autorzy:
    Sun, J.
    Kang, B.
    Zhang, H.
    Liu, Y.
    Xia, Y.
    Yao, Y.
    Liu, X.
    Powiązania:
    https://bibliotekanauki.pl/articles/357936.pdf
    Data publikacji:
    2011
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
    Tematy:
    TATB
    irreversible expansion
    XRD
    lattice parameters
    Opis:
    In this study, the irreversible expansion of TATB cylinder is investigated. No evident variation of the lattice parameters is observed on TATB crystal. The density of TATB powder decreases by only about 0.02% after it suffered from thermal cycling process at the range from -54 C to 74 C, while the density of TATB cylinder decreases by about 1.0%. It is suggested that the density variation of TATB powder has little contribution to the density decrease of TATB cylinder. Therefore, the increasing interstices between TATB powder originated from the thermal cycling should be responsible to the irreversible expansion of TATB cylinder.
    Źródło:
    Central European Journal of Energetic Materials; 2011, 8, 1; 69-79
    1733-7178
    Pojawia się w:
    Central European Journal of Energetic Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Influence of Cycle Sputtering Deposition on the Properties of Cu₂ZnSnS₄ Thin Films
    Autorzy:
    Sun, Y.
    Yao, B.
    Long, D.
    Meng, X.
    Liu, L.
    Hua, Z.
    Powiązania:
    https://bibliotekanauki.pl/articles/1398930.pdf
    Data publikacji:
    2016-06
    Wydawca:
    Polska Akademia Nauk. Instytut Fizyki PAN
    Tematy:
    78.40.Fy
    Opis:
    Three kinds of precursor thin films with stacking orders of Cu/Sn/ZnS, Cu/Sn/ZnS/Cu/Sn/ZnS and Cu/Sn/ZnS/Cu/Sn/ZnS/Cu/Sn/ZnS were prepared by magnetron sputtering and annealed with sulfur powder. The microstructure, morphology and optical properties of thin films were investigated by X-ray diffraction, the Raman scattering, scanning electron microscopy and UV-visible spectrophotometer. The increase of cycle number decreases the sulfurizing temperature of the formation of Cu₂ZnSnS₄ phase. Chemical composition can be controlled by cycle sputtering deposition. After sulfurizing at 500°C, the particle size and the band gap increase with increasing cycle number.
    Źródło:
    Acta Physica Polonica A; 2016, 129, 6; 1169-1172
    0587-4246
    1898-794X
    Pojawia się w:
    Acta Physica Polonica A
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Lifetime prediction method for MEMS gyroscope based on accelerated degradation test and acceleration factor model
    Metoda prognozowania czasu pracy żyroskopu MEMS na podstawie testu przyspieszonej degradacji i modelu współczynnika przyspieszenia
    Autorzy:
    Liu, Yao
    Wang, Yashun
    Fan, Zhengwei
    Hou, Zhanqiang
    Zhang, Shufeng
    Chen, Xun
    Powiązania:
    https://bibliotekanauki.pl/articles/301995.pdf
    Data publikacji:
    2020
    Wydawca:
    Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
    Tematy:
    MEMS gyroscope
    temperature stress
    accelerated degradation test
    acceleration factor model
    Allan variance
    żyroskop MEMS
    naprężenie cieplne
    test przyspieszonej degradacji
    model współczynnika przyspieszenia
    wariancja Allana
    Opis:
    The reliability analysis of MEMS gyroscope under long-term operating condition has become an urgent requirement with the enlargement of its application scope and the requirement of good durability. In this study we propose a lifetime prediction method for MEMS gyroscope based on accelerated degradation tests (ADTs) and acceleration factor model. Firstly, the degradation characteristic (bias instability) is extracted based on Allan variance. The effect of temperature stress on the degradation rate of bias instability is analyzed, and it shows that the degradation rate of bias instability would increase with the increase of the temperature. Secondly, the ADTs of MEMS gyroscope are designed and conducted, the degradation model of MEMS gyroscope is established based on the output voltage of MEMS gyroscope and Allan variance. Finally, the acceleration factor model of MEMS gyroscope under temperature stress is derived, and the lifetime of the MEMS gyroscope is predicted based on two group tests data under high stress level. The results show that the lifetime calculated by the acceleration factor model and mean lifetime under high stress levels is close to the mean lifetime calculated by the linear equation at normal temperature stress.
    Analiza niezawodności żyroskopu MEMS w warunkach długotrwałej pracy stała się pilną koniecznością wraz z rozszerzeniem zakresu jego zastosowania i wprowadzeniem wymogu dobrej trwałości. W niniejszym artykule, zaproponowano metodę prognozowania czasu pracy żyroskopu MEMS w oparciu o testy przyspieszonej degradacji i model współczynnika przyspieszenia. W pierwszej kolejności, wyznaczono charakterystykę degradacji (niestabilność wskazań) na podstawie wariancji Allana. Analizowano wpływ naprężenia cieplnego na szybkość degradacji w zakresie niestabilności wskazań. Analiza wykazała, że szybkość degradacji wzrastała wraz ze wzrostem temperatury. Następnie, opracowano i przeprowadzono testy przyspieszonej degradacji żyroskopu MEMS, a model jego degradacji ustalono na podstawie napięcia wyjściowego żyroskopu i wariancji Allana. Na koniec, wyprowadzono model współczynnika przyspieszenia dla żyroskopu MEMS w warunkach naprężenia cieplnego, a żywotność żyroskopu prognozowano na podstawie danych z dwóch testów grupowych przeprowadzonych w warunkach wysokiego naprężenia. Wyniki pokazują, że czas pracy obliczony na podstawie modelu współczynnika przyspieszenia i średni czas pracy przy wysokich poziomach naprężeń są zbliżone do średniego czasu pracy obliczonego na podstawie równania liniowego przy normalnym naprężeniu cieplnym.
    Źródło:
    Eksploatacja i Niezawodność; 2020, 22, 2; 221-231
    1507-2711
    Pojawia się w:
    Eksploatacja i Niezawodność
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Hydroxyl Terminated Polybutadiene: Chemical Modification and Application of these Modifiers in Propellants and Explosives
    Autorzy:
    Zhang, Qian
    Shu, Yuanjie
    Liu, Ning
    Lu, Xianming
    Shu, Yao
    Wang, Xiaochuan
    Mo, Hongchang
    Xu, Minghui
    Powiązania:
    https://bibliotekanauki.pl/articles/358004.pdf
    Data publikacji:
    2019
    Wydawca:
    Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
    Tematy:
    hydroxyl terminated polybutadiene
    HTPB
    telechelic polymer
    CSP
    PBX
    Opis:
    Hydroxyl terminated polybutadiene (HTPB) as a telechelic liquid polymer has been widely used in propellants and explosives and many modified-HTPBs have been reported in the literature. As a binder or additive in propellants and explosives, the chemical modification of HTPB for improving certain properties of propellants has been summarized in detail in this article. According to the application drawbacks of HTPB, modified-HTPB can be classified differently. Furthermore, there are polymers that have been modified on their energetic properties, such as GAP-PB-GAP, BAMO-PB-BAMO, AMMO-PB-AMMO, Nitro-HTPB, HTPB-DNB and NHTPB. Pre-polymers modified on their combustion properties include Butacene®, FPDS-g-HTPB, Fc-HTPB, BiFc-g-HTPB, HTPB→[Fe(CO)3]x, PPA-HTPB-PPA and PNBE-HTPB-PNBE. HTPBs are also modified in curing systems containing, for example ETPB, PTPB, PrTPB, AzTPB, and PUPB, and other modification results are reviewed. Additionally, this overview is expected to provide an outlook for further studies in these fields.
    Źródło:
    Central European Journal of Energetic Materials; 2019, 16, 2; 153-183
    1733-7178
    Pojawia się w:
    Central European Journal of Energetic Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Recovery of Proteins from Sweet Potato Cell Liquid by Acidification via Inoculation-Enhanced Fermentation and Determination of Functional Properties of Protein Products
    Autorzy:
    Li, Qingshuai
    Liu, Liping
    Han, Yanlei
    Zhao, Xiangying
    Yao, Mingjing
    Ma, Jing
    Han, Mo
    Zhang, Jiaxiang
    Powiązania:
    https://bibliotekanauki.pl/articles/28408449.pdf
    Data publikacji:
    2024-02-09
    Wydawca:
    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
    Tematy:
    sweet potato proteins
    Leuconostoc citreum
    protein precipitation
    digestibility
    emulsification
    foaming
    Opis:
    Starch production from fresh sweet potatoes generates process wastewater called sweet potato cell liquid (SPCL), which is rich in sweet potato protein (SPP). Currently, the commonly used protein recovery methods, such as isoelectric point precipitation and ultrafiltration, were not suitable for SPP recovery due to the low protein content of SPCL and the high cost of recovery. The feasibility of recovering SPP by SPCL acidification via inoculation-assisted fermentation was investigated in this study. The results indicated that the pH of SPCL could be reduced to approximately 4.0 within 6 h of fermentation with inoculation, resulting in an SPP extraction yield of 55.45% and purity of 66.23 g protein/100 g. With the addition of heating treatment, the extraction yield of SPP increased to 76.97–95.34%, while it maintained the purity of 66.36–70.12 g protein/100 g. The composition analysis revealed that SPP products contained sugars (below 11.5 g/100 g) in addition to protein and trace amounts of lignin and phenolics. Functional properties analysis showed that the SPP recovered by inoculation-enhanced fermentation exhibited better emulsifying and foaming properties, and higher digestibility compared to the SPP precipitated using hydrochloric acid. The method of extracting SPP from SPCL by inoculation-enhanced fermentation, as developed in this study, was a straightforward and cost-effective process that fosters significant potential for industrial applications.
    Źródło:
    Polish Journal of Food and Nutrition Sciences; 2024, 74, 1; 49-58
    1230-0322
    2083-6007
    Pojawia się w:
    Polish Journal of Food and Nutrition Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Optimal control strategy for marine SSP podded propulsion motor based on strong tracking-EPF
    Autorzy:
    Yao, W.
    Liu, Y.
    Sun, H.
    Zhang, G.
    Zhang, J.
    Zhou, M.
    Sun, M.
    Jiang, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/258784.pdf
    Data publikacji:
    2015
    Wydawca:
    Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
    Tematy:
    marine electric propulsion
    EPF
    ST-EPF
    SSP podded propulsion
    propulsion motor
    Opis:
    Aiming at the non-linearity of state equation and observation equation of SSP (Siemen Schottel Propulsor) propulsion motor, an improved particle filter algorithm based on strong tracking extent Kalman filter (ST-EKF) was presented, and it was imported into the marine SSP propulsion motor control system. The strong tracking filter was used to update particles in the new algorithm and produce importance densities. As a result, the problems of particle degeneracy and sample impoverishment were ameliorated, the propulsion motor states and the rotor resistance were estimated simultaneously using strong track filter (STF), and the tracking ability of marine SSP propulsion motor control system was improved. Simulation result shown that the improved EPF algorithm was not only improving the prediction accuracy of the motor states and the rotor resistance, but also it can satisfy the requirement of navigation in harbor. It had the better accuracy than EPF algorithm.
    Źródło:
    Polish Maritime Research; 2015, S 1; 4-9
    1233-2585
    Pojawia się w:
    Polish Maritime Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Isolation of biosynthesis related transcripts of 2,3,5,4-tetrahydroxy stilbene-2-O-beta-D-glucoside from Fallopia multiflora by suppression subtractive hybridization
    Autorzy:
    Zhao, W.
    Sheng, S.
    Liu, Z.
    Lu, Di.
    Zhu, K.
    Li, X.
    Zhao, S.
    Yao, Y.
    Powiązania:
    https://bibliotekanauki.pl/articles/58239.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Botaniczne
    Tematy:
    isolation
    biosynthesis
    transcriptome
    2,3,5,4'-tetrahydroxy stilbene-2-O-beta-D-glucoside
    Fallopia multiflora
    hybridization
    gene expression
    medicinal plant
    Chinese herb
    Opis:
    2,3,5,4'-tetrahydroxy stilbene-2-O-ß-D-glucoside (THSG) exerts multiple pharmacodynamic actions, found in Fallopia multiflora, but the biosynthesis pathway of THSG is still unclear. To clear this ambiguity, we constructed suppression subtractive hybridization (SSH) libraries to screen the genes involved in THSG biosynthesis from two F. multiflora varieties, which vary significantly in THSG content. Twelve non-redundant differentially expressed sequence tags were obtained and the full lengths of 4 unreported fragments were amplified by rapid amplification of cDNA ends. We totally got 7 fulllength transcripts, and all of them were aligned to the transcriptome and digital gene expression tag profiling database of four F. multiflora tissues (root, stem and leaf from Deqing F. multiflora and another root from Chongqing F. multiflora; data unpublished) using local BLAST. The results showed that there was a significant, organ specific difference in the expression of fragments and full-length sequences. All the sequences were annotated by aligning to nucleotide and protein databases. Kyoto Encyclopedia of Genes and Genomes pathway analysis indicated that THSG biosynthesis was correlated with multiple life activities.
    Źródło:
    Acta Societatis Botanicorum Poloniae; 2014, 83, 2
    0001-6977
    2083-9480
    Pojawia się w:
    Acta Societatis Botanicorum Poloniae
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of organic cultivation pattern on tomato production: plant growth characteristics, quality, disease resistance, and soil physical and chemical properties
    Autorzy:
    Feng, X.
    Xu, Y.
    Liu, D.
    Peng, L.
    Dong, J.
    Yao, S.
    Feng, Y.
    Feng, Z.
    Li, F.
    Hu, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/12703546.pdf
    Data publikacji:
    2020
    Wydawca:
    Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
    Opis:
    Tomato (Solanum lycopersicum L.) is one of the world’s most important cultivated vegetable. In the traditional cultivation methods, the excessive use of pesticides and fertilizers leads to an imbalance of nutrient elements in the soil, an increase in pests and diseases and a decrease in vegetable quality and yield. In the face of increasingly serious environmental and food problems, organic agriculture is considered to be an effective solution. In this experiment, the effects of organic cultivation patterns on the growth, quality, disease resistance in tomatoes, and the physical and chemical properties of soil were studied by different treatments. The results showed that the application of effective microorganisms (EM) bio-organic fertilizer in the cultivation process can significantly improve the yield, quality, and antioxidant enzyme activity of tomato. The use of straw mulching was found to significantly increase the growth, chlorophyll content, transpiration rate, and soluble sugar content of tomatoes. The application of EM bio-organic fertilizer or straw mulching significantly increased the activity of antioxidant enzyme and the expression of LeCHI gene in tomato leaves and enhanced tomato resistance to diseases. Organic production practices were found to significantly improve the soil.
    Źródło:
    Acta Scientiarum Polonorum. Hortorum Cultus; 2020, 19, 1; 71-84
    1644-0692
    Pojawia się w:
    Acta Scientiarum Polonorum. Hortorum Cultus
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of differential serum expression of three factors and pulmonary function in patients with silicosis
    Autorzy:
    Zhu, Ying
    Duan, Xia Yu
    Cheng, Yun Qi
    Yao, Xin Jing
    Xu, Hong
    Zhang, Kui Sheng
    Li, Feng Shi
    Yang, Fang
    Liu, Liang He
    Yuan, Xiang Ju
    Powiązania:
    https://bibliotekanauki.pl/articles/2086531.pdf
    Data publikacji:
    2021-08-05
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    silicosis
    pulmonary function
    early diagnosis
    ROC
    PTPN2
    factor B
    Opis:
    ObjectivesSilicosis is a chronic occupational lung disease. As was previously found by the authors, some proteins increased in the lung tissue of activated rats, and protein tyrosine phosphatase non-receptor type 2 (PTPN2), factor B, and vaccinia-related kinase 1 (VRK1) showed highly differential expressions.Material and MethodsIn this study, serum and bronchoalveolar lavage fluid samples were collected from patients with silicosis and healthy people to verify the expression of PTPN2, factor B, and VRK1. The diagnostic value of differentially expressed proteins for silicosis was judged.ResultsThe expression levels of serum PTPN2, VRK1, and factor B in patients with silicosis were significantly higher than those in the control group (p < 0.01). Higher serum PTPN2 and factor B concentrations significantly and negatively correlated with the ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1/FVC), maximum vital capacity (VCmax), FEV1, and FVC, suggesting that the high expression of PTPN2 and factor B is associated with decreased pulmonary ventilation function and restrictive ventilatory impairment in patients with silicosis. All area under curve (AUC) measurements generated from single detection events were >0.744, with PTPN2 reaching the highest value (0.858). The AUC, sensitivity, and specificity for the combined diagnosis using factor B and PTPN2 were 0.907, 86.91% and 85.07%, respectively, for factor B and PTPN2. The 3 differentially expressed proteins are potential classes of predictive biomarkers for silicosis.ConclusionsRegarding the economy and test practicality, the best diagnostic combination is factor B and PTPN2 for the analysis of AUC, sensitivity and specificity.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2021, 34, 4; 527-540
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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