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Tytuł:
Validating knowledge and technology effects to operative sustainable competitive advantage
Autorzy:
Takala, J.
Koskinen, J.
Liu, Y.
Tas, M. S.
Muhos, M.
Powiązania:
https://bibliotekanauki.pl/articles/407066.pdf
Data publikacji:
2013
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
sustainable competitive advantage
SCA
knowledge
technology rankings
manufacturing strategy
sense and respond
S&R
operational excellence
operations management
dynamic capabilities
Opis:
Purpose: This paper aims to present a fresh idea on how to model and examine the level of sustainable competitive advantage (SCA) with and without knowledge and /technology (K/T) effects in a case company’s operation by taking the manufacturing strategy’s development directions and the efficiency of resource allocation among its attributes into consideration. Design/Methodology/approach: In this paper, questionnaires are filled by two different managerial groups, company’s management team (G1) and company’s global directors (G2). The analyses based on G1, G2 and G1-G2 (mixed results) are performed and examined as well as the effect of knowledge and /technology rankings to observe the differences on how they effect on company’s operations strategy and what kind of strategy type that decision makers might follow. Besides, the effects of knowledge/technology rankings on SCA risk levels are examined on different case companies to perceive the similarities and differences with our case company. In this case study, the objectives are achieved based on several methodologies: manufacturing strategy index (MSI) [1] and sense and respond (S&R) methodology [2]. Findings: The achieved results through the model are found to be promising corresponding to the feedback from the respondents. Research limitations/implications: The model is applied only in a big sized B2B global company that produces power electronics products. Therefore, further tests need to be applied to the model in case of multiple companies from different sizes and areas to figure out the best formula in case of validation of strategic direction (MAPE, RSME or MAD). Practical implications: As a result of its wide applicability and its ease in arrangement the model has an enormous potential for strategic decision-making process and strategic analysis. Originality/Value:The model can provide a more dependable possibility of sustainable improvement to the corporate operational excellence and strategy.
Źródło:
Management and Production Engineering Review; 2013, 4, 3; 45-54
2080-8208
2082-1344
Pojawia się w:
Management and Production Engineering Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Understanding the impact of ‘hard’ and ‘soft’ elements of TQM in south-east European firms
Autorzy:
Imeri, S.
Kekäle, T.
Takala, J.
Liu, Y.
Powiązania:
https://bibliotekanauki.pl/articles/406866.pdf
Data publikacji:
2014
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
TQM
hard element
‘soft’ element
south-eastern Europe
Opis:
The study emphasizes on the understanding of the impact of ‘hard’ and ‘soft’ elements of TQM in South-Eastern European (SEE) firms in Albania, Bulgaria, Bosnia-Herzegovina, Greece, Macedonia, Montenegr, Serbia and Romania. Thus, 350 questionnaires were collected out of 1000. From different industry sectors in order to have reliable statistical measurements of the ‘hard’ and ‘soft’ side of TQM. Hence, this study adopts an exploratory rather than a confirmatory research approach. This approach seeks not only to investigate firms’ awareness and perception to TQM but also explores to what extent are firms’ familiar with TQM tools techniques, and systems as well as TQM philosophies and principles. Therefore, it can be noted TQM is this SEE firms is neither resisted nor directly accepted, rather they tend to see it from a technical aspect, being familiar and understanding only the essential of its ‘hard’ elements and less the ‘soft’ elements.
Źródło:
Management and Production Engineering Review; 2014, 5, 3; 9-13
2080-8208
2082-1344
Pojawia się w:
Management and Production Engineering Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Trace muscovite dissolution separation from vein quartz by elevated temperature and pressure acid leaching using sulphuric acid and ammonia chloride solutions
Autorzy:
Lin, M.
Pei, Z.-Y.
Lei, S.-M.
Liu, Y.-Y.
Xia, Z.-J.
Xie, F.-X.
Powiązania:
https://bibliotekanauki.pl/articles/110755.pdf
Data publikacji:
2018
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
vein quartz
muscovite
sulphuric acid
ammonium chloride
acid leaching
Opis:
Effects of sulphuric acid and ammonia chloride on muscovite dissolution were studied in acid leaching of vein quartz under elevated temperature and pressure. The leaching processes have been studied in detail by analyzing sources of impurity minerals, optimizing leaching process, analyzing leaching kinetics of Al in muscovite and charactering leaching mechanism of muscovite. The results showed that elements of Al and K mainly occurred in muscovite, and 98.10% or more of muscovite could be removed by acid leaching, while the process had limited influence on the particle size of quartz sand. Leaching of Al in the quartz ore was mainly controlled by chemical reaction. A calcination process and ammonia chloride were used for reducing chemical reaction resistance by damaging crystal structure of muscovite and providing stable acid leaching environment. Combined with the calcination process, muscovite, as a main gangue mineral, was effectively extracted during acid leaching of vein quartz at elevated temperature and pressure.
Źródło:
Physicochemical Problems of Mineral Processing; 2018, 54, 2; 448-458
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Thermally Induced Polymorphic Transformation of Hexanitrohexaazaisowurtzitane (HNIW) Investigated by in-situ X-ray Powder Diffraction
Autorzy:
Liu, Y.
Li, S.
Wang, Z.
Xu, J.
Sun, J.
Huang, H.
Powiązania:
https://bibliotekanauki.pl/articles/358065.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
HNIW
polymorphism
in situ X-ray diffraction
phase transition
heat stimulation
Opis:
The ε→γ phase transition of HNIW induced by heat was investigated with in situ X-ray powder diffraction (PXRD). The effects of purity, particle size, insensitive additives and the time of isothermal heat treatment on the phase transition were evaluated. It was found that the phase transition is irreversible with changes in temperature, and the two phases can coexist in a certain temperature range. Moreover, the initial phase transition temperature increases with increasing purity and decreasing particle size of HNIW, and thus with the approximate crystal density. The addition of graphite and paraffin wax to HNIW as insensitive additives leads to a decrease in the initial phase transition temperature, but the addition of TATB does not affect the initial phase transition temperature. Thus, TATB is a suitable insensitive additive. Moreover, at the critical temperature, the isothermal time determined the efficiency of the ε- to γ-phase transition. This work lays the foundations for the choice of molding technologies, performance test methods, ammunition storage options, as well as the manufacture of HNIW-based explosive formulations.
Źródło:
Central European Journal of Energetic Materials; 2016, 13, 4; 1023-1037
1733-7178
Pojawia się w:
Central European Journal of Energetic Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Theoretical Profile of Ring-Spun Slub Yarn and its Experimental Validation
Teoretyczne oznaczenie geometrii fantazyjnej przędzy obrączkowej typu slub i weryfikacja eksperymentalna
Autorzy:
Ma, C Q
Zhou, B M
Liu, Y
Hu, C S
Powiązania:
https://bibliotekanauki.pl/articles/232346.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
slub yarn
mathematical model
slub profile
slub length
basic yarn length
przędza obrączkowa typu slub
model matematyczny
profil slub
długość slub
podstawowa długość przędzy
Opis:
A mathematical model for the yarn count of ring-spun slub yarn was established to predict the yarn profile based on process parameters such as the fibre length, the velocities of rollers and the time of over-feeding. The theoretical study shows that the slub length depends mostly on the process parameters above. The actual slub length is a fibre length greater than the slub length designed, and the actual length of basic yarn is a fibre length less than the length of basic yarn designed. The validity of the model was then verified using four sets of experiments. The experimental results agreed well with the model predictions and showed that the present model had high prediction accuracy, which may aid in the design and production of a desired slub yarn with controlling spinning parameters.
Model matematyczny masy liniowej przędzy obrączkowej typu slub został wyznaczony w celu określenia geometrii przędzy na podstawie parametrów procesu, takich jak długość włókien, prędkości rolek i wielkości naddatku. Badania teoretyczne wskazują, że długość odcinków przędzy typu slub zależy głównie od powyżej wymienionych parametrów procesu. W artykule podano właściwości zależności teoretycznych i rzeczywistych dla przędzy fantazyjnej. Prawidłowość tego modelu została następnie poddana weryfikacji przy użyciu cztery zestawów eksperymentalnych o zróżnicowanych warunkach. Wyniki badań eksperymentalnych potwierdziły przewidywania modelu i pokazały, że obecny model zapewnia wysoką dokładność przewidywania i dzięki temu ułatwia projektowanie i produkcję określonych włókien fantazyjnych.
Źródło:
Fibres & Textiles in Eastern Europe; 2013, 1 (97); 29-34
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of different organic fluids on performances of binary slag washing water power plants
Autorzy:
Li, Z.
Liu, Y.
Dong, P.
Zhang, Y.
Xiao, S.
Powiązania:
https://bibliotekanauki.pl/articles/240438.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
slag washing water
efficiency
organic fluids
binary power cycle
wydajność
płyn organiczny
podwójny cykl zasilania
Opis:
In this paper, 3 typical organic fluids were selected as working fluids for a sample slag washing water binary power plants. In this system, the working fluids obtain the thermal energy from slag washing water sources. Thus, it plays a significant role on the cycle performance to select the suitable working fluid. Energy and exergy efficiencies of 3 typical organic fluids were calculated. Dry type fluids (i.e., R227ea) showed higher energy and exergy efficiencies. Conversely, wet fluids (i.e., R143a and R290) indicated lower energy and exergy efficiencies, respectively.
Źródło:
Archives of Thermodynamics; 2017, 38, 3; 49-62
1231-0956
2083-6023
Pojawia się w:
Archives of Thermodynamics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The distribution of different virulence grass carp reovirus strains in some neglected tissues
Autorzy:
Liang, H.R.
Fu, X.Z.
Li, N.Q.
Liu, L.H.
Lin, Q.
Li, Y.G.
Peng, Y.A.
Huang, Z.B.
Wu, S.Q.
Powiązania:
https://bibliotekanauki.pl/articles/30668.pdf
Data publikacji:
2016
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Źródło:
Polish Journal of Veterinary Sciences; 2016, 19, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Bending, Impact Fracture Behavior and Characteristics of Stainless Steel Clad Plates with Different Rolling Temperature
Autorzy:
An, Q.
Fan, K. Y.
Ge, Y. F.
Liu, B. X.
He, J.
Wang, S.
Chen, C. X.
Ji, P. G.
Tolochko, O.
Powiązania:
https://bibliotekanauki.pl/articles/2049433.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
stainless steel clad plate
interface characteristics
bending behavior
impact morphologies
delamination crack
Opis:
The interface characteristics, bending and impact behavior, as well as fracture characteristics of stainless steel clad plates fabricated by vacuum hot rolling at different rolling temperatures of 1100°C, 1200°C and 1300°C are investigated in detail. The interface bonding strength is gradually increased with the increasing rolling temperature due to the sufficient diffusion behavior of alloy element. The bending toughness and impact toughness are gradually decreased, while the bending strength increase with the increase of the rolling temperature, which is attributed to mechanisms of matrix softening and interface strengthening at high rolling temperature. Due to the weak interface at 1100°C, the bending and impact crack propagation path was displaced by delamination cracks, which in turn lead to reduction in stress intensity of the main crack, playing an effective role in toughening the stainless steel clad plates. Moreover, the impact fracture morphologies of clad plates show a typical ductile-brittle transition phenomenon, which is attributed to the matrix softening behavior with the increasing rolling temperature.
Źródło:
Archives of Metallurgy and Materials; 2021, 66, 1; 229-239
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and Theoretical Studies of a New Insensitive Explosive, 2’-Methyl-3-nitro-2’H-[1,3’-bi(1,2,4-triazole)]-5,5’-diamine
Autorzy:
Luo, J.
Liu, Y.
Wang, J.
Chai, T.
Yuan, J.
Chang, S.
Yu, Y.
Jing, S.
Ma, H.
Powiązania:
https://bibliotekanauki.pl/articles/358633.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
insensitive explosive
synthesis
theoretical studies
density functional theory
new 1,2,4-triazole derivative
Opis:
A new insensitive energetic material 2’-methyl-3-nitro-2’H-[1,3’-bi(1,2,4-triazole)]-5,5’-diamine (1) was prepared by a three-step synthesis from commercially available chemicals. The energetic title compound was comprehensively characterized by various means, including FT-IR, multinuclear (1H, 13C, 14N) NMR spectroscopy, elemental analysis, HPLC and thermal analysis. The sensitivities of the synthesized material towards various external stimuli (impact, friction) were determined according to the BAM method. The optimized structure and related thermodynamic parameters were obtained at the DFT-B3LYP/6-31+G** theoretical level. The detonation properties of the material were also predicted according to the Kamlet-Jacobs formulae and the Monte-Carlo method. The results show that the density, heat of formation, detonation velocity, detonation pressure, impact sensitivity and purity were 1.83 g/cm3, 369 kJ/mol, 7.52 km/s, 25.4 GPa, 82.3 J and 97.7%, respectively. In addition, the compound was an insensitive high explosive which could meet the requirements of high energetic materials.
Źródło:
Central European Journal of Energetic Materials; 2017, 14, 2; 269-280
1733-7178
Pojawia się w:
Central European Journal of Energetic Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and Theoretical Studies of a New High Explosive, N,N,-Bis(3-aminofurazan-4-yl)-4,4´-diamino- 2,2´,3,3´,5,5´,6,6´-octanitroazobenzene
Autorzy:
Jing, S.
Liu, Y.
Liu, D.
Guo, J.
Powiązania:
https://bibliotekanauki.pl/articles/358642.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Tematy:
BAFDAONAB
density functional theory
detonation properties
Opis:
A new high energy, low sensitivity material N,N,-bis(3-aminofurazan- 4-yl)-4,4´-diamino-2,2´,3,3´,5,5´,6,6´-octanitroazobenzene (BAFDAONAB) was synthesized from 4-chlorobenzoic acid and diaminofurazan. The structure of BAFDAONAB was characterized by FT-IR, NMR and Elemental Analyses and its purity was determined by HPLC. The optimized structure and thermodynamic parameters were obtained at the DFT- B3LYP/6-31+G** theoretical level. Its detonation properties were also predicted by the formulae of Kamlet-Jacobs and the Monte-Carlo method. The results show that the density, heat of formation, detonation velocity, detonation pressure, impact sensitivity and purity were 1.93 g/cm3, 4487.44 kJ/mol, 9.01 km/s, 35.03 GPa, 63 cm and 99.3%, respectively. In addition, the compound was an insensitive high explosive which could meet the requirements of high energetic materials.
Źródło:
Central European Journal of Energetic Materials; 2015, 12, 4; 745-755
1733-7178
Pojawia się w:
Central European Journal of Energetic Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simplified Model for Predicting Fabric Thermal Resistance According to its Microstructural Parameters
Uproszczony model dla przewidywania oporu termicznego tkanin w zależności od ich parametrów mikrostruktury
Autorzy:
Wei, J.
Xu, S.
Liu, H.
Zheng, L.
Qian, Y.
Powiązania:
https://bibliotekanauki.pl/articles/233513.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
fabric model
thermal resistance
microstructure
correlation coefficient
model tkaniny
opór termiczny tkanin
mikrostruktura
współczynnik korelacji
Opis:
This paper presents a modified model to calculate the thermal resistance of woven and knitted fabrics according to the microstructural parameters. The model was established by analysing the heat transfer process in the simplified basic unit of the fabrics. The model was modified and checked by experimental values of various fabric samples. Pearson correlation coefficients between the thermal resistance and fabric structural parameters were calculated. Results indicate that fabric thermal resistance can be predicted by the modified equation satisfactorily. The Pearson correlation coefficient from high to low follows such a sequence: fabric thickness, fabric volume density, fabric structural parameter a, fibre volume density, and fibre thermal conductivity.
W artykule przedstawiono zmodyfikowany model pozwalający obliczyć opór termiczny tkanin i dzianin w zależności od parametrów ich mikrostruktury. Model został skonstruowany poprzez analizę procesu przepływu ciepła przez uproszczoną jednostkę płaskiego materiału włókienniczego. Model został sprawdzony w praktyce przez badanie różnych próbek tkanin i dzianin. Przy ocenie zastosowano porównanie współczynników korelacji Pearsona między oporem termicznym i parametrami strukturalnymi. Wyniki wskazują, że termiczną izolację płaskich materiałów włókienniczych można przewidzieć w zadowalającym stopniu przez zaproponowane zmodyfikowane równania. Współczynniki korelacji Pearsona począwszy od dużych do małych można uszeregować dla następujących parametrów: grubość tkaniny, gęstość właściwa tkaniny, parametry strukturalne, gęstość właściwa włókien i przewodność cieplna włókien.
Źródło:
Fibres & Textiles in Eastern Europe; 2015, 4 (112); 57-60
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Role of Oxygen Coordination on the Ultrafast Demagnetization in Ferrite Nanoparticles
Autorzy:
Terrier, E.
Liu, Y.
Begin, S.
Pichon, B.
Bigot, J.
Halte, V.
Powiązania:
https://bibliotekanauki.pl/articles/1385573.pdf
Data publikacji:
2015-02
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
78.47.J-
78.20.Ls
75.30.Et
75.75.Fk
Opis:
In this work, we have studied the ultrafast dynamics of charges and spins in assemblies of magnetite (Fe₃O₄) and maghemite (γ - Fe₂O₃) nanoparticles. We demonstrate that using time-resolved magneto-optics one is able to disentangle those very similar iron oxide structures. The Fe₃O₄ nanoparticles are elaborated by hydrothermal decomposition and deposited by drop on a glass substrate. γ - Fe₂O₃ nanoparticles assemblies have been obtained by annealing the Fe₃O₄ nanoparticles. Comparing time resolved transmission and Faraday rotation, our measurements show that in case of Fe₃O₄ the demagnetization occurs after the thermalization of the charges, as expected from previous works on ultrafast quenching of magnetization in ferromagnetic nanostructures. On the contrary, in the case of maghemite nanoparticles, an acceleration of the demagnetizing occurs, leading to a simultaneous charges and spins dynamics. We attribute this behavior to the rearrangement of vacancies and annealing of crystal defects in maghemite.
Źródło:
Acta Physica Polonica A; 2015, 127, 2; 345-346
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Role of dissolved mineral species in quartz flotation and siderite solubility simulation
Autorzy:
Luo, X.
Wang, Y.
Ma, M.
Song, S.
Zhang, Y.
Deng, J.
Liu, J.
Powiązania:
https://bibliotekanauki.pl/articles/109459.pdf
Data publikacji:
2017
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
quartz
solubility
siderite
calcium ion
temperature
flotation
Opis:
Quartz is, in most cases, the major gangue mineral found in the iron ores. Although it can be activated by calcium at strong alkaline pH, quartz nevertheless, reports to the concentrate with Fe when the iron ores contain siderite. It causes a poor concentrate grade and separation between quartz and iron minerals. The effect of siderite on reverse anionic flotation of quartz from hematite was studied in our previous investigations. In this work, the effect of siderite dissolution on the quartz recovery in the froth product and the effect of pH, ions and temperature on siderite dissolution were investigated. Microflotation, PHREEQC simulation, solution chemistry calculation and Fourier transform infrared spectroscopy (FTIR) measurements were conducted. It was observed that the dissolved species of siderite exhibited negative impact on quartz flotation. This influence became weak to some extent by either stripping the dissolved species or shortening dissolution time. Siderite was easily dissolved in the presence of calcium ion under strong alkaline conditions and its solubility increased with increasing the calcium ion concentrate and temperature. When the calcium ion was added as an activator of quartz under strong alkaline conditions (pH>9.96), calcium existed mainly in the CaCO3 precipitation form according to the solubility rule in the presence of siderite. This form could adsorb onto quartz surfaces and further the chemical reaction between starch and quartz was monitored by FTIR measurements. This study provides a further supplement for previous study. A potential strategy is suggested that finding a collector used at low temperature or flotation under neutral (or weak alkaline) medium is helpful to the reverse flotation of iron ores containing siderite.
Źródło:
Physicochemical Problems of Mineral Processing; 2017, 53, 2; 1241-1254
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Robust adaptive fuzzy filters output feedback control of strict-feedback nonlinear systems
Autorzy:
Tong, S.
Liu, C.
Li, Y.
Powiązania:
https://bibliotekanauki.pl/articles/908148.pdf
Data publikacji:
2010
Wydawca:
Uniwersytet Zielonogórski. Oficyna Wydawnicza
Tematy:
system nieliniowy
sterowanie rozmyte
sprzężenie zwrotne
nonlinear system
adaptive fuzzy control
backstepping
small-gain approach
K-filters
Opis:
In this paper, an adaptive fuzzy robust output feedback control approach is proposed for a class of single input single output (SISO) strict-feedback nonlinear systems without measurements of states. The nonlinear systems addressed in this paper are assumed to possess unstructured uncertainties, unmodeled dynamics and dynamic disturbances, where the unstructured uncertainties are not linearly parameterized, and no prior knowledge of their bounds is available. In recursive design, fuzzy logic systems are used to approximate unstructured uncertainties, and K-filters are designed to estimate unmeasured states. By combining backstepping design and a small-gain theorem, a stable adaptive fuzzy output feedback control scheme is developed. It is proven that the proposed adaptive fuzzy control approach can guarantee the all the signals in the closed-loop system are uniformly ultimately bounded, and the output of the controlled system converges to a small neighborhood of the origin. The effectiveness of the proposed approach is illustrated by a simulation example and some comparisons.
Źródło:
International Journal of Applied Mathematics and Computer Science; 2010, 20, 4; 637-653
1641-876X
2083-8492
Pojawia się w:
International Journal of Applied Mathematics and Computer Science
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Review and future perspectives on the integration characteristics for equine lentivirus in the host genome
Autorzy:
Yu, Y.-Y.
Xu, M.-S.
Liang, H.
Wang, H.-Y.
Yu, C.-Q.
Liu, Q.
Powiązania:
https://bibliotekanauki.pl/articles/16647532.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
lentivirus
equine infectious anemia virus
integration
long interspersed elements
Opis:
Despite over 40 years of research on the human immunodeficiency virus type 1 (HIV-1) vaccine, we still lack a considerable progress. Equine infectious anemia virus (EIAV) is a lentivirus in the Retroviridae family, akin to HIV-1 in genome structure and antigenicity. EIA is an important infectious disease in equids, characterized by anemia, persistent infection, and repeated fevers. The EIAV attenuated vaccine in China is the only lentiviral vaccine used on a large scale. Elucidating the mechanism of waning and induction of protective immunity from this attenuated vaccine strain will provide a critical theoretical basis and reference point for vaccine research, particularly in the development of lentivirus vaccines, with far-reaching scientific value and social significance. In this paper, we summarize the information related to EIAV integration site selection, particularly for the Chinese EIAV attenuated vaccine strains on the equine genome. This may improve our mechanistic understanding of EIAV virulence reduction at the host genome level. The obtained data may help elucidate the biological characteristics of EIAV, particularly the Chinese attenuated EIAV vaccine strain, and provide valuable information regarding retroviral infections, particularly lentiviral infection and associated therapeutic vectors.
Źródło:
Polish Journal of Veterinary Sciences; 2023, 26, 1; 163-172
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 74

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