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Tytuł:
Azo dye wastewater treatment in a novel process of biofilm coupled with electrolysis
Autorzy:
Zou, Haiming
Chu, Lin
Wang, Yang
Powiązania:
https://bibliotekanauki.pl/articles/204706.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
azo dye wastewater treatment
color removal
biofilm
electrolysis
bioelectrochemical system
Opis:
Azo dye wastewater treatment is urgent necessary nowadays. Electrochemical technologies commonly enable more efficient degradation of recalcitrant organic contaminants than biological methods, but those rely greatly on the energy consumption. A novel process of biofilm coupled with electrolysis, i.e., bioelectrochemical system (BES), for methyl orange (MO) dye wastewater treatment was proposed and optimization of main influence factors was performed in this study. The results showed that BES had a positive effect on enhancement of color removal of MO wastewater and 81.9% of color removal efficiency was achieved at the optimum process parameters: applied voltage of 2.0 V, initial MO concentration of 20 mg/L, glucose loads of 0.5 g/L and pH of 8.0 when the hydraulic retention time (HRT) was maintained at 3 d, displaying an excellent color removal performance. Importantly, a wide range of effective pH, ranging from 6 to 9, was found, thus greatly favoring the practical application of BES described here. The absence of a peak at 463 nm showed that the azo bond of MO was almost completely cleaved after degradation in BES. From these results, the proposed method of biodegradation combined with electrochemical technique can be an effective technology for dye wastewater treatment and may hopefully be also applied for treatment of other recalcitrant compounds in water and wastewater
Źródło:
Archives of Environmental Protection; 2019, 45, 3; 38-43
2083-4772
2083-4810
Pojawia się w:
Archives of Environmental Protection
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evaluation of integrated UFCW-MFC reactor for azo dye wastewater treatment and simultaneous bioelectricity generation
Autorzy:
Zou, Haiming
Chu, Lin
Wang, Yan
Powiązania:
https://bibliotekanauki.pl/articles/207646.pdf
Data publikacji:
2020
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
COD
UFCW-MFC
methyl orange
wastewater
ChZT
oranż metylowy
oczyszczanie ścieków
Opis:
An up-flow constructed wetland (UFCW) incorporating a novel membrane-less air-cathode single-chamber microbial fuel cell (MFC) was designed to treat dye wastewater and simultaneously generate bioelectricity. The performance of UFCW-MFC was evaluated via Methyl Orange (MO) and chemical oxygen demand (COD) removal rates and the output voltage. For comparison, the performance of a single UFCW was also assessed. A repeatable and stable voltage output of about 0.44±0.2 V was obtained in UFCW-MFC. The MO and COD removal rates in UFCW-MFC were 93.5 and 57.2%, respectively, significantly higher than those in single UFCW (75.4 and 42.6%, respectively), suggesting the obvious enhancement of electrodes on MO and COD removal. The anode zone of UFCW-MFC made the most contribution to MO and COD removal compared with other layers. The oxidation-reduction potential (ORP) and dissolved oxygen (DO) profiles showed that the anaerobic environment was well developed in the lower part of UFCW-MFC (0–24 cm) and the upper part (41–42 cm) had a good aerobic environment, thus greatly contributing to the MO anaerobic reduction and aerobic degradation of breakdown products. These results obtained here suggest that the UFCW-MFC may provide an effective alternative for the treatment of dye wastewater and simultaneous bioelectricity generation.
Źródło:
Environment Protection Engineering; 2020, 46, 1; 63-72
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Molecular cloning, bioinformation analysis and expression of the strictosidine synthase in Dendrobium officinale
Autorzy:
Zhu, Y.-F.
Fan, H.-H.
Li, D.-H.
Jin, Q.
Zhang, C.-M.
Zhu, L.-Q.
Song, C.
Cai, Y.-P.
Lin, Y.
Powiązania:
https://bibliotekanauki.pl/articles/12715947.pdf
Data publikacji:
2020
Wydawca:
Uniwersytet Przyrodniczy w Lublinie. Wydawnictwo Uniwersytetu Przyrodniczego w Lublinie
Opis:
The enzyme strictosidine synthase (STR, EC: 4.3.3.2) plays a key role in the biosynthetic pathway of terpenoid indole alkaloid (TIA). It catalyzes the condensation of the tryptamine and secologanin to form 3α(S)-strictosidine, which is the common precursor of all TIAs. In this paper, a STR gene designated as DoSTR (GenBank: KX068707) was first cloned and characterized from Dendrobium officinale with rapid amplified cDNA ends method (RACE). DoSTR has a length of 1380bp with 1179bp open reading frame encoding 392 amino acids. BlastP analyses showed that its amino acid sequence was classified into Str_synth superfamily. qRT-PCR showed that DoSTR was expressed in all tissues tested, with a significantly higher level in flower and the lowest in stem. Four different treatments with MeJA, SA, ABA and AgNO₃, respectively, could induce the DoSTR expression to a different extent. And the effect of MeJA was the most obvious and transcript level of DoSTR induced by MeJA was 20.7 times greater than that of control at 48 hours after treatment. Furthermore, it was found that DoSTR was localized in vacuole through transient expression in tobacco. The characterization and expression of DoSTR can help in further studying the role of DoSTR in the biosynthesis of TIAs in D. officinale. This study may throw light on the alkaloid biosynthesis pathway of D. officinale.
Źródło:
Acta Scientiarum Polonorum. Hortorum Cultus; 2020, 19, 3; 111-124
1644-0692
Pojawia się w:
Acta Scientiarum Polonorum. Hortorum Cultus
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A triboelectric nanogenerator based on a pendulum-plate wave energy converter
Autorzy:
Zhu, Shenglin
Yang, Shaohui
Li, Hui
Huang, Yan
Du, Zhichang
Fan, Jianyu
Lin, Zhonghua
Powiązania:
https://bibliotekanauki.pl/articles/32892836.pdf
Data publikacji:
2022
Wydawca:
Politechnika Gdańska. Wydział Inżynierii Mechanicznej i Okrętownictwa
Tematy:
TENG
wave energy
computer simulation
semi-physical simulation
Źródło:
Polish Maritime Research; 2022, 4; 155-161
1233-2585
Pojawia się w:
Polish Maritime Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Time-frequency Representation -enhanced Transfer Learning for Tool Condition Monitoring during milling of Inconel 718
Autorzy:
Zhou, Yuqing
Sun, Wei
Ye, Canyang
Peng, Bihui
Fang, Xu
Lin, Canyu
Wang, Gonghai
Kumar, Anil
Sun, Weifang
Powiązania:
https://bibliotekanauki.pl/articles/24200823.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Polskie Naukowo-Techniczne Towarzystwo Eksploatacyjne PAN
Tematy:
tool condition monitoring
time-frequency analysis
Markov Transition Field
transfer learning
Opis:
Accurate tool condition monitoring (TCM) is important for the development and upgrading of the manufacturing industry. Recently, machine-learning (ML) models have been widely used in the field of TCM with many favorable results. Nevertheless, in the actual industrial scenario, only a few samples are available for model training due to the cost of experiments, which significantly affects the performance of ML models. A time-series dimension expansion and transfer learning (TL) method is developed to boost the performance of TCM for small samples. First, a time-frequency Markov transition field (TFMTF) is proposed to encode the cutting force signal in the cutting process to two-dimensional images. Then, a modified TL network is established to learn and classify tool conditions under small samples. The performance of the proposed TFMTF-TL method is demonstrated by the benchmark PHM 2010 TCM dataset. The results show the proposed method effectively obtains superior classification accuracies for small samples and outperforms other four benchmark methods.
Źródło:
Eksploatacja i Niezawodność; 2023, 25, 2; art. no. 165926
1507-2711
Pojawia się w:
Eksploatacja i Niezawodność
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The Effect of Power Ultrasound on Microstructure Evolution During the Transient Liquid Stage of Ultrasonic-Promoted TLP Bonding SiCp/Al MMCs
Autorzy:
Zhou, Changzhuang
Ma, Lin
Zhu, Chao
Cui, Qinghe
Liang, Jindi
Song, Yujian
Powiązania:
https://bibliotekanauki.pl/articles/2174569.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
transient liquid phase bonding
silicon carbide reinforced aluminum matrix composites
ultrasonics
zinc interlayer
Opis:
Ultrasound-promoted transient liquid phase bonding (U-TLP) is a high quality, high efficiency, and low-cost method for fast bonding of difficult-wetting materials in the atmospheric environment. In this paper, U-TLP was used to bond SiC particles reinforced aluminium-based metal matrix composite which particle volume fraction was 70%. The pure zinc foil was used as the intermediate layer. The effects of ultrasonic on microstructure evolution and mechanical properties of joints during the transient liquefaction stage were investigated. The mechanism of ultrasonic effects in the transient liquefaction stage of U-TLP was also inducted. The results showed that high volume fraction SiCp/Al MMCs were bonded well at low temperature in the air environment. Ultrasonic vibration can remove the oxide film on the surface of aluminum matrix composites, enhance the wettability of SiC particles with weld metal, promote atomic diffusion and homogenization of SiC particles, and improve the welding quality and efficiency. Reasonable increase of ultrasonic vibration time could effectively improve the joint strength.
Źródło:
Archives of Metallurgy and Materials; 2022, 67, 4; 1283--1291
1733-3490
Pojawia się w:
Archives of Metallurgy and Materials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Establishment of 5-Fluorouracil-resistant canine mammary tumor cell line
Autorzy:
Zhou, B.
Zhang, D.
Pei, S.M.
Zhang, K.
Du, H.C.
Jin, Y.P.
Lin, D.G.
Powiązania:
https://bibliotekanauki.pl/articles/30283.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
Canine mammary tumors are the most common neoplasms in intact female dogs. The surgery cannot always solve the problem, chemotherapy are recommend to these patients. However, chemotherapy could always fail because of multidrug resistance (MDR). Through stepwise increasing 5-Fluorouracil (5-FU) concentration in the culture medium, a 5-FU-resistant canine mammary tumor cell line CMT7364/5-FU was established to disclose the molecular mechanism of the drug resistance. Cell morphology, cell sensitivity to drugs, growth curves, expression of proteins, and chemo-sensitivity in vivo were compared between the parental cell line and resistant cell line. As compared it to its parental cell line (CMT7364), CMT7364/5-FU showed different morphology, cross-resistant to other chemo-drugs and a prolonged population doubling time (PDT). The drug efflux pump proteins (ABCB1 and ABCG2) in CMT7364/5-FU were up-regulated. In vivo, the similar result revealed that CMT7364/5-FU cell line was more resistant to 5-FU. In conclusion, a 5-FU-resistant canine mammary tumor cell line (CMT7364/5-FU) was successfully established, it can serve as a good model for researching the mechanism of MDR and screening effective agents to reverse drug resistance.
Źródło:
Polish Journal of Veterinary Sciences; 2017, 20, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Experimental investigation and modelling of hot forming B₄C/AA6061 low volume fraction reinforcement composites
Autorzy:
Zheng, K.
Lin, J.
Wu, G.
Hall, R. W.
Dean, T. A.
Powiązania:
https://bibliotekanauki.pl/articles/280433.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Mechaniki Teoretycznej i Stosowanej
Tematy:
Metal Matrix Composite (MMC)
hot compression
AA6061
B₄C
dislocation
Opis:
This paper presents an experimental investigation of the hot deformation behaviour of 15% B₄C particle reinforced AA6061 matrix composites and the establishment of a novel corresponding unified and physically-based visco-plastic material model. The feasibility of hot forming of a metal matrix composite (MMC) with a low volume fraction reinforcement has been assessed by performing hot compression tests at different temperatures and strain rates. Examination of the obtained stress-strain relationships revealed the correlation between temperature and strain hardening extent. Forming at elevated temperatures enables obvious strain rate hardening and reasonably high ductility of the MMC. The developed unified material model includes evolution of dislocations resulting from plastic deformation, recovery and punching effect due to differential thermal expansion between matrix and reinforcement particles during non-steady state heating and plastic straining. Good agreement has been obtained between experimental and computed results. The proposed material model contributes greatly to a more thorough understanding of flow stress behaviour and microstructural evolution during the hot forming of MMCs.
Źródło:
Journal of Theoretical and Applied Mechanics; 2018, 56, 2; 457-469
1429-2955
Pojawia się w:
Journal of Theoretical and Applied Mechanics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acoustic Emission Response and Damage Process for Q235 Steel in an in Situ Tensile Test
Autorzy:
Zhang, Ying
Li, Yue
Lai, Huan Sheng
Bai, Chunmei
Liu, Kang Lin
Powiązania:
https://bibliotekanauki.pl/articles/177752.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
Q235
damage
acoustic emission
in situ tensile test
Opis:
Q235 steel is widely used in engineering and construction. Therefore, it is important to identify the damage mechanism and the acoustic emission (AE) response of the material to ensure the safety of structures. In this study, an AE monitor system and an in situ tensile test with an optical microscope were used to investigate the AE response and insight into the damage process of Q235 steel. The surface of the specimen was polished and etched before the test in order to improve the quality of micrographs. Two kinds of AE responses, namely a burst and a continuous signal, were recorded by the AE monitor system during the test. Based on the in situ test, it was observed that the damage of Q235 steel was induced by the crystal slip and the inclusion fracture. Since the crystal slip was an ongoing process, continuous AE signals were produced, while burst AE signals were possibly produced by the inclusion fracture which occurred suddenly with released higher energy. In addition, a great number of AE signals with high amplitude were observed during the yielding stage and then the number and amplitude decreased.
Źródło:
Archives of Acoustics; 2019, 44, 4; 807-813
0137-5075
Pojawia się w:
Archives of Acoustics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synergistic Effects of Plasma Treatment and Fabric Structure on Stab-Resistance Performances of STF/Aramid Composite Fabrics
Synergistyczny wpływ obróbki plazmowej i struktury tkaniny na parametry odporności na przebicie tkanin kompozytowych STF/aramid
Autorzy:
Zhang, Xiayun
Li, Ting-Ting
Wang, Yunlong
Li, Mengxuan
Lin, Jia-Horng
Powiązania:
https://bibliotekanauki.pl/articles/234167.pdf
Data publikacji:
2020
Wydawca:
Sieć Badawcza Łukasiewicz - Instytut Biopolimerów i Włókien Chemicznych
Tematy:
aramid fibre
weaving
stab resistance
shear thickening fluid
plasma treatment
włókno aramidowe
tkanie
odporność na przebicie
ciecz zagęszczana ścinaniem
obróbka plazmowa
Opis:
In order to improve the contribution of STF and fabric to the stab resistance of STF-impregnated aramid soft armour materials, the plasma treatment of various fabric structures was conducted. This study explored the interactive effects of plasma treatment, fabric structure and particle size on the spike and knife resistance properties of plasma-treated STF/Aramid fabrics. Fumed silica and polyethylene glycol (PEG) based STFs were prepared with various particle sizes (15 nm, 75 nm) at a solid content of 15%. Various weave structures of fabrics (plain, 2/2 twill, 5/3 satin, 2/2 basket) were impregnated with STF and then plasma-treatment conducted. The rheological behaviour of STF in various silica sizes as well as the spike and knife quasi-static stab resistances of the resultant plasma-treated STF/aramid fabrics in various weave structures were both explored. The results show that the various weave structures of STF/Aramid fabrics treated with plasma exhibited a significant enhancement of quasi-static spike resistance. Furthermor, 2/2 twill, 5/3 satin and basket weaving plasma-treated STF/Aramid with a coarser silica particle in STF showed a higher improvement in quasi-static spike resistance. Interactive effect results show that the plasma treatment of fabric and the silica size in STF affected spike resistance more significantly, while knife resistance was only significantly affected by the fabric structure.
Aby poprawić odporność na przebicie tkaniny kompozytowych STF/aramid przeprowadzono ich obróbkę plazmową. Zbadano interaktywny wpływ obróbki plazmowej, struktury tkaniny i wielkości cząstek na właściwości odporności na przebicie kolcami i nożem tkanin kompozytowych STF/aramid poddanych działaniu plazmy. Przygotowano STF na bazie zmatowionej krzemionki koloidalnej i glikolu polietylenowego (PEG) o różnych wielkościach cząstek (15 i 75 nm) o zawartości substancji stałych wynoszącej 15%. Różne struktury splotu tkanin (m.in. gładkie, 2/2 diagonalne i 5/3 satynowe) zostały zaimpregnowane STF, a następnie przeprowadzono obróbkę plazmą. Badano zarówno zachowanie reologiczne w przypadku różnych rozmiarów krzemionki, jak i quasi-statyczne odporności na przebicie kolcami i nożem otrzymanych tkanin STF/aramid poddanych obróbce plazmowej i wykonanych z zastosowaniem różnych struktur splotu. Wyniki pokazały, że różne struktury splotu tkanin STF aramid poddanych obróbce plazmą wykazały znaczne zwiększenie quasi-statycznej odporności na przebicie kolcami. Ponadto tkany z grubszą cząstką krzemionki w STF wykazały poprawę w quasi-statycznej odporności na przebicie kolcami. Wyniki pokazały, że obróbka plazmowa tkaniny i rozmiar krzemionki w STF wpłynęły bardziej na odporność na przebicie kolcami, podczas gdy na wytrzymałość na przebicie nożem istotny wpływ miała tylko struktura tkaniny.
Źródło:
Fibres & Textiles in Eastern Europe; 2020, 2 (140); 67-75
1230-3666
2300-7354
Pojawia się w:
Fibres & Textiles in Eastern Europe
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Experimental study of quartz classification in the enhanced gravity field using Falcon concentrator
Autorzy:
Zhang, Ling
Yang, Lu
Hou, Haochun
Zhao, Yan
Lin, Jun
Zhang, Zeliang
Bu, Caiyun
Zheng, Xinran
Fu, Dong
Powiązania:
https://bibliotekanauki.pl/articles/27323652.pdf
Data publikacji:
2023
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
classification
enhanced gravity field
fine particles
fish-hook
Opis:
The classification and separation of minerals happen in the traditional gravity separation simultaneously. This paper focuses on the classification performance of quartz particles in the enhanced gravity field. The classification efficiency of single quartz particles decreased then increased with the increase of rotational angular velocity, while it decreased with the increase of backwash water pressure. The classification efficiency of -0.5 +0.25mm, -0.25 +0.125mm, -0.125 +0.074mm, -0.074 +0.045mm and -0.045mm quartz was higher than the corresponding narrow size of -0.5mm quartz in general. The “fish-hook” phenomenon appeared in the partition curve of -0.5mm quartz under small/large rotational angular velocity and small backwash water pressure, and the dip point could be found in fine particles region, which indicated that the “fish-hook” was closely related with operating parameters and particle size. A medium rotational angular velocity and larger backwash water pressure could be helpful to avoid the appearance of “fish-hook” in fine particles region and achieve a better classification performance. This investigation is beneficial to understand the regularity of particle migration in the enhanced gravity field.
Źródło:
Physicochemical Problems of Mineral Processing; 2023, 59, 6; art. no. 175242
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A new adaptation for in vitro co-culture of single porcine parthenogenetic embryos using feeder cells
Autorzy:
Zhang, L.
Lin, Z.
Hua, Z.
Zheng, X.
Xiao, H.
Hua, W.
Ren, H.
Zhu, Z.
Molenaar, A.
Bi, Y.
Powiązania:
https://bibliotekanauki.pl/articles/2087368.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
feeder cells
porcine
embryos
in vitro
Źródło:
Polish Journal of Veterinary Sciences; 2019, 4; 711-716
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
CO2 concentration affects in vitro pig embryo developmental capacity
Autorzy:
Zhang, L.
Lin, Z.
Bi, Y.
Zheng, X.
Xiao, H.
Hua, Z.
Powiązania:
https://bibliotekanauki.pl/articles/2087657.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
CO2
developmental capacity
pig embryos
in vitro
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 3; 609-614
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Simulation of the peak flow reduction of small reservoirs. A case study of the Brown Bridge Pond, Michigan, USA
Autorzy:
Zhang, Jing
Guo, Chen-lin
Xie, Guang-Ming
Xing, Bing
Powiązania:
https://bibliotekanauki.pl/articles/27323980.pdf
Data publikacji:
2023
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Opis:
Due to the high frequency and great damage of flood disasters, it is important to reduce the flood peak when it goes through the reservoir. A hydraulic model which integrates the implicit equation of water balance, water head-discharge carves, and water head-storage carves together, is proposed to simulate the flood peak reduction of a small reservoir. The proposed method was employed to simulate the flood peak reduction in the Brown Bridge Reservoir, Michigan, US. The results show that the proposed method can simulate the flood peak reduction in a small reservoir, and the Brown Bridge Dam can reduce the flood peak when hundred-year floods go through. When all gates or spillways are fully opened, the initial water head of the reservoir significantly influences the capacity of flood peak reduction. When the initial water head of the Brown Bridge Reservoir is 240.18 and 241.40 m, the hundred-year flood peak would be reduced to 23.11 m3/s and 25.85 m3/s, respectively. By optimizing the gates or spillways, the hundred-year flood peak could be reduced. When the initial water head of the reservoir is 241.40 and 240.18 m, the hundred-year flood peak would be reduced to 17.98 and 16.54 m3/s, respectively
Źródło:
Environment Protection Engineering; 2023, 49, 3; 83--94
0324-8828
Pojawia się w:
Environment Protection Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type VI.
Autorzy:
Zhang, Jiayi
Dai, Jianliang
Zhao, Enpeng
Lin, Yun
Zeng, Li
Chen, Jinzhong
Zheng, Huari
Wang, Yu
Li, Xin
Ying, Kang
Xie, Yi
Mao, YuMin
Powiązania:
https://bibliotekanauki.pl/articles/1041522.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ovary
ePAD
peptidylarginine deiminase
hPADVI
Opis:
Peptidylarginine deiminase (PAD) catalyzes the post-translational modification of protein through the conversion of arginine to citrulline in the presence of calcium ions. Human, similar to rodents, has four isoforms of PAD (type I, II, III and IV/V), each of which is distinct in substrate specificity and tissue specific expression. In our large-scale sequencing project, we identified a new human PAD cDNA from a human fetal brain cDNA library. The putative protein encoded by this cDNA is designated hPADVI. Expression analysis of hPADVI showed that it is mainly expressed in adult human ovary and peripheral blood leukocytes. We conclude that hPADVI may be orthologous to mouse ePAD, basing on sequence comparison, chromosome localization and exon-intron structure analysis. PAD-mediated deimination of epithelial cell keratin resulting in cytoskeletal remodeling suggests a possible role for hPADVI in cytoskeletal reorganization in the egg and in early embryo development. This study describes a new important member of the human PAD family.
Źródło:
Acta Biochimica Polonica; 2004, 51, 4; 1051-1058
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł

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