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Wyświetlanie 1-15 z 37
Tytuł:
François Chapeville (1924–2020) – in memoriam
Francois Chapeville (1924–2020) – wspomnienie
Autorzy:
Legocki, Andrzej B.
Powiązania:
https://bibliotekanauki.pl/articles/2121470.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
François Chapeville (Franciszek Chrapkiewicz)
biochemistry
biosynthesis of proteins
adapter hypothesis
Jacques Monod Institute of Molecular Biology
Opis:
François Chapeville (Franciszek Chrapkiewicz), an outstanding Polish bioche- mist, spent his entire adult life in France. After graduating in veterinary and biochemistry there, he completed a postdoctoral fellowship at the Fritz Lipmann laboratory at Rockefeller University in New York. There, he conducted studies that proved that the genetic information encoded in DNA is deciphered in the process of protein biosynthesis via adapter tRNA molecules (adapter hypothesis). In the years 1979–1991 he was appointed director of Jacques Monod Institute of Molecular Biology at the University VII in Paris. He was a great promoter of Polish-French cooperation in the natural sciences. He passed away in Paris at the age of 96. He was buried in his hometown of Strzyżów in the Podkarpacie region.
Źródło:
Nauka; 2021, 3; 185-188
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hypotheses and dilemmas around the origin and uniqueness of life
Autorzy:
Legocki, Andrzej B.
Powiązania:
https://bibliotekanauki.pl/articles/1916654.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
origin of replication
chemical evolution
Opis:
The emergence of life on Earth and its almost infinite diversity, reflected by a myriad of living organisms, are among the dilemmas that have forever fascinated scientists and philosophers. Today, we are still not able to determine what exactly initiated the chain of events leading to the rise of life – the mechanism of replication of initial structures or perhaps the occurrence of first metabolic reactions. Further approximations of these issues shall probably constitute an overwhelming driving force for future development of life sciences.
Źródło:
Nauka; 2020, 3
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Humanistic context of the great challenges of science
Autorzy:
Legocki, Andrzej B.
Powiązania:
https://bibliotekanauki.pl/articles/704574.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
great challenges of science
humanistic context
Opis:
Philosophical concepts have always been closely related to the development of basic sciences. For example, great mathematical theories put forth at the turn of the century, and general theory of relativity were crucial for the advancement of physical sciences and at the same time had a great impact on the formation of a new science philosophy. They also initiated a new era of exploring the Universe, thus opening many issues in the fields of astrophysics and astronomy. In biology, the theory of evolution has greatly impacted the understanding of such fundamental issues as the origin of living species and the occurrence of the phenomenon of life on Earth. Another breakthrough in life sciences was a result of the progress in molecular biology which concerned sequencing genomes and modification of genetic resources of living organisms. These great achievements have led to formation of several new fields of life sciences such as: synthetic biology, systemic biology as well as personalized medicine.
Źródło:
Nauka; 2019, 4
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Translational and structural analysis of the shortest legume ENOD40 gene in Lupinus luteus
Autorzy:
Podkowinski, Jan
Zmienko, Agnieszka
Florek, Blazena
Wojciechowski, Pawel
Rybarczyk, Agnieszka
Wrzesinski, Jan
Ciesiolka, Jerzy
Blazewicz, Jacek
Kondorosi, Adam
Crespi, Martin
Legocki, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1040638.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
nitrogen fixation
transcript structure
ENOD40
phylogeny
Opis:
Two early nodulin 40 (enod40) genes, ENOD40-1, the shortest legume ENOD40 gene, and ENOD40-2, were isolated from Lupinus luteus, a legume with indeterminate nodules. Both genes were expressed at similar levels during symbiosis with nitrogen-fixing bacteria. ENOD40 phylogeny clustered the L. luteus genes with legumes forming determinate nodules and revealed peptide similarities. The ENOD40-1 small ORF A fused to a reporter gene was efficiently expressed in plant cells, indicating that the start codon is recognized for translation. The ENOD40-1 RNA structure predicted based on Pb(II)-induced cleavage and modeling revealed four structurally conserved domains, an absence of domain 4 characteristic for legumes of indeterminate nodules, and interactions between the conserved region I and a region located upstream of domain 6. Domain 2 contains Mg(II) ion binding sites essential for organizing RNA secondary structure. The differences between L. luteus and Glycine max ENOD40 RNA models suggest the possibility of a switch between two structural states of ENOD40 transcript.
Źródło:
Acta Biochimica Polonica; 2009, 56, 1; 89-102
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Man in a modern world. Reflections on the new philosophy of nature
Autorzy:
Legocki, Andrzej B.
Powiązania:
https://bibliotekanauki.pl/articles/703432.pdf
Data publikacji:
2008
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
philosophy of nature
evolution
man and its environment
Opis:
Philosophical theories developed concurrently with scientific thoughts and have consequently contributed to the identification of the main purposes of cognition, thus influencing the essence of progress in civilization. One of the main questions posed here was whether the development of living species in nature is subject to a blind chance in evolution only. Rapid development of science and its exceptional culmination in the 20th century redefined the special place of human being and its natural environment.
Źródło:
Nauka; 2008, 1
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wprowadzenie
Autorzy:
Legocki, Andrzej B.
Powiązania:
https://bibliotekanauki.pl/articles/704037.pdf
Data publikacji:
2005
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Źródło:
Nauka; 2005, 3
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Yellow lupine gene encoding stearoyl-ACP desaturase - organization, expression and potential application.
Autorzy:
Zaborowska, Żaneta
Starzycki, Michał
Femiak, Iwona
Świderski, Michał
Legocki, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1043803.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
nitrogen fixation
root nodules
stearoyl-ACP desaturase
fatty acids
yellow lupine
Opis:
A gene for the Δturase specific to stearoyl-ACP (acyl carrier protein) was identified from yellow lupine (Lupinus luteus) cDNA and genomic libraries through the differential display method. The desaturase transcript appears in plants infected with Bradyrhizobium sp. (Lupinus) as revealed by Northern hybridization, RT-PCR and expression of β-glucuronidase under the desaturase promoter. A small amount of desaturase transcript was also detected in uninfected plants, which suggests that the gene does not belong to the strict nodule-specific sequences. The desaturase provides unsaturated fatty acids for additional cell membrane synthesis. During nodule and symbiosome development a peribacteroid membrane is formed and the requirement for membrane surface increases, thus the level of desaturase expression is also higher. Transgenic plants of Nicotiana tabacum with overexpression of the full-length lupine stearoyl-ACP desaturase sequence were obtained. They revealed higher content of unsaturated fatty acids (especially oleic acid) in comparison with control plants.
Źródło:
Acta Biochimica Polonica; 2002, 49, 1; 29-42
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reduction of bacterial genome size and expansion resulting from obligate intracellular lifestyle and adaptation to soil habitat.
Autorzy:
Stępkowski, Tomasz
Legocki, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/1044125.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
symbiosis
Rickettsia
rhizobium
genome
Buchnera
Opis:
Prokaryotic organisms are exposed in the course of evolution to various impacts, resulting often in drastic changes of their genome size. Depending on circumstances, the same lineage may diverge into species having substantially reduced genomes, or such whose genomes have undergone considerable enlargement. Genome reduction is a consequence of obligate intracellular lifestyle rendering numerous genes expendable. Another consequence of intracellular lifestyle is reduction of effective population size and limited possibility of gene acquirement via lateral transfer. This causes a state of relaxed selection resulting in accumulation of mildly deleterious mutations that can not be corrected by recombination with the wild type copy. Thus, gene loss is usually irreversible. Additionally, constant environment of the eukaryotic cell renders that some bacterial genes involved in DNA repair are expandable. The loss of these genes is a probable cause of mutational bias resulting in a high A+T content. While causes of genome reduction are rather indisputable, those resulting in genome expansion seem to be less obvious. Presumably, the genome enlargement is an indirect consequence of adaptation to changing environmental conditions and requires the acquisition and integration of numerous genes. It seems that the need for a great number of capabilities is common among soil bacteria irrespective of their phylogenetic relationship. However, this would not be possible if soil bacteria lacked indigenous abilities to exchange and accumulate genetic information. The latter are considerably facilitated when housekeeping genes are physically separated from adaptive loci which are useful only in certain circumstances.
Źródło:
Acta Biochimica Polonica; 2001, 48, 2; 367-381
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 37

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