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Tytuł:
Certain protein transducing agents convert translocated proteins into cell killers
Autorzy:
Tcherniuk, Siergiej
Fiser, Anne-Laure
Derouazi, Madiha
Toussaint, Bertrand
Wang, Yan
Wojtal, Izabela
Kondo, Eisaku
Szolajska, Ewa
Chroboczek, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/1039725.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cytotoxic protein
cell transduction
protein delivery
cell translocation
transducing peptides
Opis:
The majority of proteins are unable to translocate into the cell interior. Hence for peptide- and protein-based therapeutics a direct intracytoplasmic delivery with the aid of transducing agents is an attractive approach. We wanted to deliver to the cell interior a putatively cytotoxic protein VPg. Protein transduction was achieved in vitro with three different commercial products. However, in our hands, delivery of various control proteins without known deleterious effects, as well as of protein VPg, always induced cell death. Finally, we used a novel transducing peptide Wr-T, which was not toxic to cultured cells, even in a quite large range of concentrations. Most importantly, control protein delivered to cells in culture did not display any toxicity while VPg protein exerted a strong cytotoxic effect. These data show that results obtained with cell-penetrating agents should be interpreted with caution.
Źródło:
Acta Biochimica Polonica; 2012, 59, 3; 433-439
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Julio Cortázar : des débuts en littérature sous le signe de la controverse (1947)
Autorzy:
Bobard, Laure
Powiązania:
https://bibliotekanauki.pl/articles/701292.pdf
Data publikacji:
2012
Wydawca:
Wydawnictwo Uniwersytetu Śląskiego
Opis:
In 1947, Julio Cortázar writes “Teoría del túnel,” an essay in which he expresses his desire to overhaul literature, emphasizing the need for the writer, whom he refers to as a “rebel,” to distance himself from certain literary models which he considers fossilised. The essay comes through as an invitation to change one’s writing habits and, at the same time, strive to develop a language capable of depicting man in all his complexity. The following paper demonstrates that El Examen (1950) and Diario de Andrés Fava - a diary initially meant to be part of the novel - are experimental fields that enable the author to explore the possibilities of transgressing the traditional literary codes and implement the proposals he had put forward a few years before in “Teoría del túnel.” Key words: Cortázar, novel, transgression, literary codes.
Źródło:
Romanica Silesiana; 2012, 7
1898-2433
2353-9887
Pojawia się w:
Romanica Silesiana
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reconsidération étymologique et historique du vocable dialectologie
Autorzy:
Budzinski, Laure
Powiązania:
https://bibliotekanauki.pl/articles/638309.pdf
Data publikacji:
2012
Wydawca:
Uniwersytet Jagielloński. Wydawnictwo Uniwersytetu Jagiellońskiego
Tematy:
etymology, borrowing, dialectology, French
Opis:
Etymological and Historical Reconsideration of the French Vocable dialectologie Etimologia prossima of the French prevails in this methodological approach in order to show how the vocable was introduced into the French lexicon. With a modern view on the etymology we can’t just present the etymon but it’s essential to build the historical link between the etymon and the vocable that we describe. First, it’s necessary to consider what the main etymological dictionaries propose (for example FEW and TLF) to reveal what are the gaps for a correct description. So we must give a first attestation. Indeed dictionaries only proposed so far an event marking the field of dialectology but not a first term’s attestation. When we examine the first attestation of the French vocable it’s possible to see that fr. dialectologie is a borrowing from German and not a French creation.
Źródło:
Romanica Cracoviensia; 2012, 12, 1
2084-3917
Pojawia się w:
Romanica Cracoviensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
La narration et le corps dans Il faut beaucoup aimer les hommes de Marie Darrieussecq
Autorzy:
Pujol, Marie-Laure
Powiązania:
https://bibliotekanauki.pl/articles/1627892.pdf
Data publikacji:
2015-12-01
Wydawca:
Uniwersytet Gdański. Wydawnictwo Uniwersytetu Gdańskiego
Opis:
This paper aims at examining the paradox expressed by Marie Darrieussecq when she states that “even in [her] novels of absence, there is material” in Il faut beaucoup aimer les hommes. The narrative takes shape around Solange, an actress, whose existence is threatened as her own physique decays, consumed by her passion for Kouhouesso which makes her a fading ghostly figure. The storytelling of the organic body has to be considered under three aspects : phenomenology, deterritorialization and representation.
Źródło:
Cahiers ERTA; 2015, 8; 101-113
2300-4681
Pojawia się w:
Cahiers ERTA
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Legitimacy and heritage circulation: the genealogical taste of Itxassou’s cherries (French Basque Country)
Autorzy:
Briand, Anne-Laure
Powiązania:
https://bibliotekanauki.pl/articles/470047.pdf
Data publikacji:
2015
Wydawca:
Poznańskie Towarzystwo Przyjaciół Nauk
Tematy:
Cherries
French Basque Country
Heritagization
Legitimacy
‚Etxe’
Opis:
In Itxassou in the French Basque Country, various forms of the heritagization of the cherries are coexisting : festivals, derivatives and ‚small-scale’ heritages are some of them. Three groups of people are taking part in the heritagization system. With the development of those various forms, an important matter appeared: the legitimacy of granting an heritage status. Different dimensions are intertwined in the heritagization of the cherries: the ‘territory’, the ‘terroir’ and the ‘land’. This study deals with the ‚land’ part of the subject which is closely related to the model of the Basque home, called the ‚Etxe’. The ‚Etxe’ ‚is telling’ its inhabitants what they can hand down. On the one hand, the ‚Etxe’ seems to directly grant a heritage status, as it enables to operate a selection between various items. On the other hand, the ‚Etxe’ seems to show its inhabitants how to grant a heritage status.
Źródło:
Our Europe. Ethnography – Ethnology – Anthropology of Culture; 2015, 4; 47-58
2299-4645
Pojawia się w:
Our Europe. Ethnography – Ethnology – Anthropology of Culture
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Épaves de Julien Green : une acédie moderne
Épaves by Julien Green : a modern acedia
Autorzy:
Andevert, Anne-Laure
Powiązania:
https://bibliotekanauki.pl/articles/1627949.pdf
Data publikacji:
2017-06-01
Wydawca:
Uniwersytet Gdański. Wydawnictwo Uniwersytetu Gdańskiego
Opis:
Julien Green immerses the reader in some oppressive boredom‐filled atmosphere, he also experienced. He was used to boredom, turning into acedia, taedium vitae, melancholy, nostalgia, overpowering neurasthenia, all this linked with his mother’s early death, the flesh/mind conflict or, even the exarcerbated awareness of a void existence. Acedia – a genuine individual experience – leaves the Greenian character facing an empty, pointless existence. Acedia spreads its invisible tentacles around the character who feels how empty life without God is. Apathetic, lazy, idle and weak, he flees all inner life, causing his immutable loneliness. This aridity is seen in an empty town and the immutable life he sinks into. The fatal row he witnessed, reveals his cowardice and creates a gap in his consciousness : the image of a strong, respectable man cracks turning acedia into an ordeal condemning him to painfully cohabitate with himself thus annihilating all ambition and selftranscendence.
Źródło:
Cahiers ERTA; 2017, 11; 269-289
2300-4681
Pojawia się w:
Cahiers ERTA
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vom Sprachfeminismus zum gendergerechten Sprachgebrauchin der BRD
Autorzy:
Gautherot, Laure
Powiązania:
https://bibliotekanauki.pl/articles/2081188.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
feminism
gender-sensitive language
communicative norms
Opis:
This article focuses upon the evolution of an ideologically dominated linguistic feminism to the application of gender-sensitive language in contemporary German. Three linguistic strategies – distinction, neutralization, graphostylistic disturbance – with corresponding linguistic forms will be examined in two German university guidelines, intending to reveal which ones are considered as pragmatically acceptable in communicative practice.
Źródło:
Kwartalnik Neofilologiczny; 2017, 1; 39-53
0023-5911
Pojawia się w:
Kwartalnik Neofilologiczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Didactique et Sociologie, deux sciences pour appréhender le rapport aux savoirs de lapprenant
Didactics and Sociology, Two Sciences to Apprehend the Relationship with Knowledge of the Learner
Dydaktyka i socjologia, dwie nauki mające na celu uchwycenie relacji z wiedzą ucznia
Autorzy:
Nafti-Malherbe, Caterine
Jurado, Marie-Laure
Powiązania:
https://bibliotekanauki.pl/articles/1811404.pdf
Data publikacji:
2018
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
dydaktyka
socjologia
wiedza
umiejętności
dyscyplinarne rekompozycje
antropologia pedagogiczna
didactics
sociology
knowledge
disciplinary-recomposition
pedagogical
anthropology
Opis:
Pisząc ten artykuł, staramy się wykazać, że związek między dydaktyką a socjologią może zmniejszyć nierówności edukacyjne. Uważamy, że musimy zerwać z podziałem różnych nauk, aby przejść do wspólnej wiedzy. Ta nowa wiedza naukowa będzie szczególnie przydatna we Francji do ograniczenia niepowodzeń szkolnych ze względu na heterogeniczność uczniów, aby uwzględniając wiedzę jako fakt społeczny, przyczynić się wraz ze specjalistami dydaktyki do integracji w transpozycji dydaktycznej osobistego związku ucznia z wiedzą. Transpozycja dydaktyczna i stosunek do wiedzy odsyłają nas do antropologii przedmiotu.
With this article we aim to demonstrate that the link between didactics and sociology could reduce inequalities at school. We think we must break up with the partition between the different sciences and move towards a mutualised knowledge. This new scientific knowledge will contribute, particularly in France, to reduce school failure due to the heterogeneity between the pupils, to take into account knowledge as a social fact and doing so contribute with the didacticians to integrate in the didactic transposition the personal relationship of the learner to knowledge. The didactic transposition and the relationship to knowledge refer us to an anthropology of the subject.
Źródło:
Roczniki Pedagogiczne; 2018, 10(46), 2; 49-59
2080-850X
Pojawia się w:
Roczniki Pedagogiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Narrative in Virtual Reality? Anatomy of a Dream Reborn
Autorzy:
Ryan, Marie-Laure
Powiązania:
https://bibliotekanauki.pl/articles/1964577.pdf
Data publikacji:
2018
Wydawca:
Ośrodek Badawczy Facta Ficta
Tematy:
Virtual reality
narrative
interactivity
immersion
panoramic
representation
experience of embodiment
Opis:
When the big leap forward of computer technology took place for the general public in the 80s and 90s, virtual reality technology (VR) was touted as the “next big thing” that digital media would bring into our lives. Janet Murray’s influential book Hamlet on the Holodeck (1997) explored the possibility of turning narrative into the “immersive, interactive experience generated by a computer” that defines VR. But VR did not live up to its expectations, and after the year 2000, it faded from the radar of popular interest. It regained attention around 2011 when Mark Zuckerberg, the founder/CEO of Facebook, bought Oculus Rift, the maker of a relatively cheap and lightweight head-mounted display. Currently available VR narratives are distinguished from other digital narratives through three-dimensional images, interactive panoramic representations, and the ability to manipulate our experience of our own body. In this article I discuss three projects that use some of these resources in order to assess the storytelling potential of the medium: Clouds Over Sidra, a documentary about a camp for Syrian refugees in Jordan; Hard World for Small Things, a fictionalized version of the shooting of an unarmed black man by white policemen; and VRwandlung, a project that puts the user in the situation of the hero of Franz Kafka’s The Metamorphosis, who wakes up one day to discover that he has been transformed into a giant insect. Basing my judgment of this limited corpus, I assess the potential of VR narrative with respect to four kinds of immersion: ludic, spatial, temporal and emotional.
Źródło:
Facta Ficta. Journal of Theory, Narrative & Media; 2018, 2, 2; 91-111
2719-8278
Pojawia się w:
Facta Ficta. Journal of Theory, Narrative & Media
Dostawca treści:
Biblioteka Nauki
Artykuł

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