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Wyszukujesz frazę "Langner, E." wg kryterium: Autor


Wyświetlanie 1-3 z 3
Tytuł:
Tumour cell growth-inhibiting properties of water extract isolated from heated potato fi bre (Potex)
Autorzy:
Langner, E.
Rzeski, W.
Kaczor, J.
Kandefer-Szerszen, M.
Powiązania:
https://bibliotekanauki.pl/articles/3113.pdf
Data publikacji:
2009
Wydawca:
Instytut Medycyny Wsi
Źródło:
Journal of Pre-Clinical and Clinical Research; 2009, 03, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neuroprotective activity of 2-amino-1,3,4-thiadiazole derivative 4BrABT – an in vitro study
Autorzy:
Juszczak, M.
Walczak, K.
Langner, E.
Karpinska, M.
Matysiak, J.
Rzeski, W.
Powiązania:
https://bibliotekanauki.pl/articles/49999.pdf
Data publikacji:
2013
Wydawca:
Instytut Medycyny Wsi
Opis:
4BrABT (2-(4-Bromophenylamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole) is a compound known for its interesting in vitro anticancer profile. 4BrABT inhibited proliferation and motility of several cancer cell lines in concentrations which were not toxic to normal cells. A major problem associated with cancer chemotherapy, but also caused by environmental factors such as pesticides, is neurotoxicity. Therefore, the aim of the presented study was an in vitro evaluation of the neuroprotective activity of this compound. 4BrABT activity (1–100 μM) was tested in cultures of mouse neurons, rat astrocytes and rat oligodendrocytes. A possible protective action of the compound in different neurodegenerative models, as serum deprivation (SD), excitotoxicity (presence of 500 μM glutamate in culture medium), as well as cisplatin toxicity (astroglia – 50 μM and oligodendroglia – 100 μM) was investigated. Cell viability in the tested cultures was assessed with the use of LDH and MTT methods. Moreover, 4BrABT ability to prevent the cisplatin-induced apoptosis in astrocyte and oligodendrocyte cultures was analysed after Hoechst 33342 fluorostaining. The obtained results indicate that 4BrABT was not toxic to neurons, astrocytes and oligodendrocytes. Moreover, a decrease in the neuronal LDH level was observed, which may suggest the ability of 4BrABT to act as a trophic agent. Furthermore, the protective action of the studied compound was shown in neuronal cultures exposed to neurotoxic conditions (presence of glutamate and trophic stress) and in cisplatin-treated astrocytes and oligodendrocytes. The expression of anticancer and neuroprotective activity raises hopes for the potential use of 4BrABT as a safe anticancer drug, or neuroprotective agent in chemotherapy-associated neurotoxicity.
Źródło:
Annals of Agricultural and Environmental Medicine; 2013, 20, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Some problems of plasma-material interactions in fusion devices
Autorzy:
Glazunov, G.
Volkov, E.
Lapshin, V.
Tereshin, V.
Sadowski, M.
Langner, J.
Stanisławski, J.
Powiązania:
https://bibliotekanauki.pl/articles/146712.pdf
Data publikacji:
2000
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
boron-carbide erosion
plasma-material interaction
TiN-coated stainless-steel
Opis:
The paper concerns some questions connected with the interaction of high-temperature plasma-ion fluxes with solid materials inside experimental chambers used for fusion-oriented research, and particularly inside the Torsatron-type facilities. Mechanisms of the boron carbide erosion are described and discussed. Also described is the behaviour of TiN-coated stainlesssteel surfaces under the irradiation with hydrogen plasma-ion fluxes. In summary, there are described damages in the boron carbide layers and changes in the composition of the TiN-coatings.
Źródło:
Nukleonika; 2000, 45, 3; 209-213
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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