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Tytuł:
Właściwości przeciwrzęsistkowe pochodnych eterów zawierających reszty aminowe i chlorowcoaryloalkilowe
Trichomonacidal properties of the derivatives of ethers containing amine and halogenaryloalkyl groups
Autorzy:
Białasiewicz, D.
Kotełko, B.
Kurnatowska, A.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2152441.pdf
Data publikacji:
1990
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia lekarska
rzesistek pochwowy
Trichomonas vaginalis
srodki lecznicze
pochodne eterow
reszty aminowe
reszty chlorowcoaryloalkilowe
substancje biologicznie czynne
zwiazki organiczne
dzialanie przeciwpasozytnicze
aktywnosc rzesistkobojcza
Opis:
The trichomonacidal activity in vitro of 6 new derivatives of theirs containing amine and halogenaryloalkyl groups in comparison with metronidazole, ornidazole and tinidazole has been examined. For all the examined compounds curves of action were obtained after 30 min. and lethal concentrations for 50% population (CL₅₀) of three strains of T. vaginalis used for experiments were calculated. The trichomonacidal action of the following compounds was especialy strong: 2-/1-methylpiperazin-4-yl/ethyl-4-chlorbenzhydryl ether dihydrochloride and 2-/1-benzylperhydro-1,4-diazepin-4-yl/ethyl 2,4-dichlorbenzyl ether dihydrochloride. The trichomonacidal action of these compounds was several times stronger than that of metronidazole and tinidazole.
Źródło:
Wiadomości Parazytologiczne; 1990, 36, 5-6; 281-285
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Właściwości przeciwrzęsistkowe pochodnych eterów zawierających reszty aminowe i chlorowcoaryloalkilowe
Trichomonacidal properties of the derivatives of ethers containing amine and halogenaryloalkyl groups
Autorzy:
Bialasiewicz, D.
Kotelko, B.
Kurnatowska, A.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/836304.pdf
Data publikacji:
1990
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parazytologia lekarska
rzesistek pochwowy
Trichomonas vaginalis
srodki lecznicze
pochodne eterow
reszty aminowe
reszty chlorowcoaryloalkilowe
substancje biologicznie czynne
zwiazki organiczne
dzialanie przeciwpasozytnicze
aktywnosc rzesistkobojcza
Opis:
The trichomonacidal activity in vitro of 6 new derivatives of theirs containing amine and halogenaryloalkyl groups in comparison with metronidazole, ornidazole and tinidazole has been examined. For all the examined compounds curves of action were obtained after 30 min. and lethal concentrations for 50% population (CL₅₀) of three strains of T. vaginalis used for experiments were calculated. The trichomonacidal action of the following compounds was especialy strong: 2-/1-methylpiperazin-4-yl/ethyl-4-chlorbenzhydryl ether dihydrochloride and 2-/1-benzylperhydro-1,4-diazepin-4-yl/ethyl 2,4-dichlorbenzyl ether dihydrochloride. The trichomonacidal action of these compounds was several times stronger than that of metronidazole and tinidazole.
Źródło:
Annals of Parasitology; 1990, 36, 5-6
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zdolnosc dezaminacji aminokwasow przez wybrane gatunki grzybow
Autorzy:
Bialasiewicz, D
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/841229.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
gatunki grzybow
grzyby
Candida
rozklad aminokwasow
dezaminacja
parazytologia
Trichosporon
Geotrichum
aminokwasy
Opis:
We have studied the capability of dissociation of 22 L-form aminoacids by 27 strains of fungi belonging to species: Candida, Cryptococcus, Geotrichum, Rhodotorula, Saccharomyces, Trichosporon. Fungal strains were cultured on agar medium with phenyl red and studied aminoacid. Disamination of an aminoacid by a fungus resulted in alkalisation of the medium and change of its colour from yellow to pink. Strains from genus Trichosporon and Geotrichum decomposed the most aminoacids (15-16), while fungi from genus Candida decomposed less aminoacid (1-8). Strains form species Candida famata, C. kefyr, C. lambica. C. rugosa, C. neoformans, R. mucilaginosa and S. cerevisiae did not show any ability to desaminate any of the 22 aminoacids used in the study. Aminoacids most frequently disaminated by the studied strains of fungi included acidic aliphatic aminoacids and their amides: L-aspartic acid, L-asparagine, L-glutaminic acid, L-glutamine and neutral aliphatic aminoacids: L-glycin, L-alanine, L-serine. Aromatic and sulphur aminoacids (L-cysteine, L-cystine) were not decomposed by the studied fungal strains.
Źródło:
Annals of Parasitology; 2001, 47, 3; 339-344
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zdolność dezaminacji aminokwasów przez wybrane gatunki grzybów
THE CAPABILITY OF DISSOCIATION OF AMINOACIDS BY SELECTED STRAINS OF FUNGI
Autorzy:
Białasiewicz, D.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2147943.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
gatunki grzybow
grzyby
Candida
rozklad aminokwasow
dezaminacja
parazytologia
Trichosporon
Geotrichum
aminokwasy
Opis:
We have studied the capability of dissociation of 22 L-form aminoacids by 27 strains of fungi belonging to species: Candida, Cryptococcus, Geotrichum, Rhodotorula, Saccharomyces, Trichosporon. Fungal strains were cultured on agar medium with phenyl red and studied aminoacid. Disamination of an aminoacid by a fungus resulted in alkalisation of the medium and change of its colour from yellow to pink. Strains from genus Trichosporon and Geotrichum decomposed the most aminoacids (15-16), while fungi from genus Candida decomposed less aminoacid (1-8). Strains form species Candida famata, C. kefyr, C. lambica. C. rugosa, C. neoformans, R. mucilaginosa and S. cerevisiae did not show any ability to desaminate any of the 22 aminoacids used in the study. Aminoacids most frequently disaminated by the studied strains of fungi included acidic aliphatic aminoacids and their amides: L-aspartic acid, L-asparagine, L-glutaminic acid, L-glutamine and neutral aliphatic aminoacids: L-glycin, L-alanine, L-serine. Aromatic and sulphur aminoacids (L-cysteine, L-cystine) were not decomposed by the studied fungal strains.
Źródło:
Wiadomości Parazytologiczne; 2001, 47, 3; 339-344
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktualne mozliwosci stosowania lekow przeciwgrzybiczych w niektorych chorobach skory
Autorzy:
Choczaj-Kukula, A.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/838759.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
choroby skory
grzybica skory
leki przeciwgrzybicze
stosowanie
Źródło:
Annals of Parasitology; 2004, 50, 2; 125-133
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aktualne możliwości stosowania leków przeciwgrzybiczych w niektórych chorobach skóry
Current possibilities of using antimycotic drugs in the treatment of various skin disorders.
Autorzy:
Choczaj-Kukuła, A.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2146442.pdf
Data publikacji:
2004
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
choroby skory
grzybica skory
leki przeciwgrzybicze
stosowanie
Opis:
The purpose of this article is to review the literature data on the therapeutic protocols and the results of using some antimycotics in different skin diseases. In addition to the antimycotic action, particular antifungal drugs such as itraconazole, ketoconazole and terbinafine exhibit anti-inflammatory activity by inhibiting the synthesis of 5-lipooxygenase metabolites. As these metabolites are involved in a number of inflammatory and immunoreactive processes the dual action of the drugs may be suitably exploited in the treatment of some skin diseases which are otherwise difficult to cure. Another rationale for the use of antimycotics in certain skin disorders is their action against Malassezia. It has been recently demonstrated that Malassezia, present as a commensal in the epidermis, may play an important role in inducing certain inflammatory processes by stimulating cytokine production by keratinocytes. The antimycotics proved to be useful in the therapy of the following skin conditions: seborrheic dermatitis, Malassezia folliculitis, perioral dermatitis and papulopustular rosacea, as well as adult atopic dermatitis. The use of antimycotic drugs in amicrobial palmoplantar pustulosis and sebopsoriasis remains controversial. These medications are also an alternative in the treatment of leishmaniosis.
Źródło:
Wiadomości Parazytologiczne; 2004, 50, 2; 125-133
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Brachypodium distachyon – a model plant to study grass genome structure, dynamics and evolution
Autorzy:
Idziak, D.
Hasterok, R.
Betekhtin, A.
Borowska-Zuchowska, N.
Braszewska-Zalewska, A.
Chwialkowska, K.
Gorkiewicz, R.
Kus, A.
Kwasniewska, J.
Kwasniewski, M.
Robaszkiewicz, E.
Siwinska, D.
Wolny, E.
Chrominski, K.
Tkacz, M.
Powiązania:
https://bibliotekanauki.pl/articles/951271.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Brachypodium distachyon
model plant
grass
genome structure
Expressed Sequence Tag programme
fluorescent in situ hybridization
chromosome painting
DNA methylation
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Charakterystyka wartosci odżywczej i głównych cech jakościowych odtłuszczonego mleka w proszku z wytwórni krajowych
Characterostics of quality and nutritional value of skim milk powder from Polish factories
Autorzy:
Korolczuk, J.
Kwasniewska, I.
Kunachowicz, H.
Secomska, B.
Szkilladziowa, W.
Powiązania:
https://bibliotekanauki.pl/articles/875763.pdf
Data publikacji:
1974
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
mleko w proszku
produkty krajowe
mleko odtluszczone w proszku
wartosc odzywcza
cechy fizykochemiczne
barwa
sucha masa
azot ogolny
popiol
kwasowosc
tiamina
ryboflawina
kwas askorbinowy
sklad aminokwasowy
metionina
cystyna
Źródło:
Roczniki Państwowego Zakładu Higieny; 1974, 25, 6
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrazliwosc na mikonazol i itrakonazol szczepow grzybow z rodzaju Candida wyodrebnionych od pacjentow hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/840111.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Źródło:
Annals of Parasitology; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:
Kurnatowska, A.K.
Kwaśniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/2143561.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Opis:
It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
Źródło:
Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:
Wiadomości Parazytologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Big data significance in remote medical diagnostics based on deep learning techniques
Autorzy:
Kwaśniewska, A.
Giczewska, A.
Rumiński, J.
Powiązania:
https://bibliotekanauki.pl/articles/1940561.pdf
Data publikacji:
2017
Wydawca:
Politechnika Gdańska
Tematy:
telemedicine
deep learning
multimedia databases
big data
telemedycyna
uczenie głębokie
multimedialne bazy danych
duże zbiory danych
Opis:
In this paper we discuss the evaluation of neural networks in accordance with medical image classification and analysis. We also summarize the existing databases with images which could be used for training deep models that can be later utilized in remote home-based health care systems. In particular, we propose methods for remote video-based estimation of patient vital signs and other health-related parameters. Additionally, potential challenges of using, storing and transferring sensitive patient data are discussed.
Źródło:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2017, 21, 4; 309-319
1428-6394
Pojawia się w:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Termiczne pory roku w Hornsundzie (SW Spitsbergen)
Thermal seasons in Hornsund (SW Spitsbergen)
Autorzy:
Kwaśniewska, E.
Pereyma, J.
Powiązania:
https://bibliotekanauki.pl/articles/260633.pdf
Data publikacji:
2004
Wydawca:
Stowarzyszenie Klimatologów Polskich
Tematy:
pory roku
Spitsbergen
seasons
Opis:
In the studies on climate and its changes in the polar regions it is essential to determine climatic seasons which can be based on thermal, circular and phenological criteria but also according to different types of weather. The aim of this research is to determine thermal seasons, to characterize their structure and general regularities, which may make the more detailed environmental monitoring of these areas possible. According to many authors, a climatic characterization of a given area should be presented through defining its seasonal structure. This article attempts to find natural thermal periods in the polar climate, which differ from the conventional, fixed monthly or quarterly periods: spring III-V, summer VI-VIII, autumn IX-XI, winter XII-II; often accepted by many scientists in order to make the characterization of the course of selected meteorological elements easier. The analysis of the seasonal structure of the climate of Hornsund is based on the data from the period of 1990-1999. The indices that characterize the initial and final dates, the overall duration of the thermal seasons, and estimation of the seasons? changeability in thermal terms have been taken into consideration. Calendar boundaries have been set according to the method proposed by Kosiba (1958), in which the date that begins the period of the domination of days with the daily average air temperature (Ti) typical for a given season is accepted as the season?s boundary. As the quite significant changeability of the daily average air temperature complicates the choice of initial and final dates of seasons, additional criteria are used: the number of days proper for thermal season (w), days warmer than w?days, days colder than w-days, the average air temperature and other. This study provides a division into four seasons according to Baranowski?s criteria (1986) accepted on the basis of an analysis of the annual course of air temperature in Hornsund, the accepted thermal criteria are as follows: spring -2.5°C <= Ti <= 2.5°C, summer Ti >= 2.5°C, autumn -2,5°C <= Ti <= 2.5°C, winter Ti <= -2,5°C. The characteristics of a vegetative period are also defined. Its duration in the polar regions is difficult to estimate. If we accept the most commonly used criterion of the stabilization of the daily average air temperature over +5°C, we will face the situation in which the vegetative period in the polar regions is either very short or does not occur at all. Phenological observations of Sorkappland - S Spitsbergen (Dubiel, 1988) made it possible to estimate a natural thermal threshold 0?C which begins the vegetative period. The development of most plants and their first flower buds occurs in average air temperature of approximately 0?C. Blooming and producing seeds, on the other hand, occur when the air temperature exceeds 2.5°C. Seasons (fig. 17), determined on the basis of daily average air temperatures, characterize and emphasize the changeability of thermal conditions and the specifics of the polar climate very well, what results in the conclusions enumerated below: - in the researched decade the initial and final dates and the overall duration of the thermal seasons are characterized by great changeability, - the most stable, with regard to the initial date, are spring and summer, - the most changeable, with regard to duration, are autumn and summer, - the most thermally stable season is summer. The least thermally stable season is autumn, - transitional seasons have a tendency to prolong: mainly autumn (the effect is that winter becomes shorter) and to a lesser extent spring. Winter and summer shorten, - the analysis of the line of this trend reveals that summer gets slightly colder. Spring and winter do not show any significant changes, - the most visible tendency is a downward tendency of autumn temperatures - the effect of the prolonged duration towards winter, - a vegetative period shows a tendency to begin later and to finish slightly earlier. The final date, however, does not reveal any significant tendency for changes.
Źródło:
Problemy Klimatologii Polarnej; 2004, 14; 157-169
1234-0715
Pojawia się w:
Problemy Klimatologii Polarnej
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cryptococcus neoformans: occurrence in human environment and virulence factors
Autorzy:
Kwasniewska, J.
Powiązania:
https://bibliotekanauki.pl/articles/840419.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mouse
infection
mice
man
Cryptococcus neoformans
Filobasidiella
human environment
guinea pig
virulence factor
fungi
rat
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
DNA damage in Crepis capillaris cells in response to in vitro condition
Autorzy:
Kwasniewska, J.
Nawrocki, W.
Siwinska, D.
Maluszynska, J.
Powiązania:
https://bibliotekanauki.pl/articles/19251.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Opis:
We analyzed DNA damage, mitotic activity and polyploidization in Crepis capillaris callus cells during short- and long-term in vitro culture, and the influence of plant growth regulators on these processes. Changes in the concentration of growth regulators altered the stability of callus. The level of DNA damage was highly dependent on the growth regulator composition of the medium. Cytokinin at high concentrations damaged DNA in the absence of auxin. Short- and long-term callus differed in sensitivity to growth regulators. Mitotic activity changed when callus was transferred to medium with modified growth regulators. Callus cell nuclear DNA content increased with age and in response to plant growth regulators. Hormones played a role in the genetic changes in C. capillaris callus culture. We demonstrated the usefulness of C. capillaris callus culture as a model for analyzing the effect of culture conditions, including plant growth regulators, on genetic stability.
Źródło:
Acta Biologica Cracoviensia. Series Botanica; 2012, 54, 2
0001-5296
Pojawia się w:
Acta Biologica Cracoviensia. Series Botanica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Jubileusz 50-lecia pracy naukowej prof.zw.dr hab.n.med. Alicji Kurnatowskiej w dziedzinie parazytologii i mikologii lekarskiej
Autorzy:
Kwasniewska, J
Powiązania:
https://bibliotekanauki.pl/articles/838796.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
mikologia lekarska
dzialalnosc naukowa
parazytologia lekarska
biografie
jubileusz
Kurnatowska Alicja biografia
Źródło:
Annals of Parasitology; 2003, 49, 1; 105-110
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 30

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